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RNASEH1

  • RNASEH1
  • Protein-coding gene in the species Homo sapiens

    H1 also known as RNase H1 is an enzyme that in humans is encoded by the RNASEH1 gene. The RNase H1 is a non-specific endonuclease and catalyzes the cleavage

    RNASEH1

    RNASEH1

    RNASEH1

  • DNA replication
  • Biological process

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    DNA replication

    DNA replication

    DNA_replication

  • Mitochondrial myopathy
  • Muscle disorders caused by mitochondrial dysfunction

    mitochondrial DNA deletions, autosomal recessive/dominant) POLG, SLC25A4, RNASEH1, TWNK, TK2, POLG2, DGUOK, TOP3A, RRM2B AR/AD PS157640 Mitochondrial DNA

    Mitochondrial myopathy

    Mitochondrial myopathy

    Mitochondrial_myopathy

  • Retroviral ribonuclease H
  • Escherichia coli and Bacillus halodurans RNases H as well as to human RNaseH1. In general, the folded structures of retroviral RNase H domains take the

    Retroviral ribonuclease H

    Retroviral ribonuclease H

    Retroviral_ribonuclease_H

  • Ribonuclease H
  • Enzyme family

    Hart CE, Hung G, De Hoyos CL, et al. (June 2016). "Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver

    Ribonuclease H

    Ribonuclease H

    Ribonuclease_H

  • POLE (gene)
  • Protein-coding gene in humans

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    POLE (gene)

    POLE (gene)

    POLE_(gene)

  • Origin of replication
  • Sequence in a genome

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    Origin of replication

    Origin of replication

    Origin_of_replication

  • DNA polymerase epsilon
  • Class of enzymes

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    DNA polymerase epsilon

    DNA_polymerase_epsilon

  • Replicon (genetics)
  • DNA region replicating from a single origin

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    Replicon (genetics)

    Replicon_(genetics)

  • POLE2
  • Protein-coding gene in the species Homo sapiens

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    POLE2

    POLE2

    POLE2

  • POLD3
  • Protein-coding gene in the species Homo sapiens

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    POLD3

    POLD3

    POLD3

  • POLE4
  • Protein-coding gene in the species Homo sapiens

    replicating sequence Single-strand binding protein SSBP2 SSBP3 SSBP4 RNase H RNASEH1 RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon

    POLE4

    POLE4

    POLE4

  • DRIP-seq
  • DRIP-seq except for the use of MBP-RNASEH1 endonuclease instead of the S9.6 mAb for R-loops recovery. MBP-RNASEH1 provides an alternative to S9.6 mAb

    DRIP-seq

    DRIP-seq

  • List of human protein-coding genes 7
  • 13833 RNASE12 HGNC:24211; Q5GAN4 13834 RNASE13 HGNC:25285; Q5GAN3 13835 RNASEH1 HGNC:18466; O60930 13836 RNASEH2A HGNC:18518; O75792 13837 RNASEH2B HGNC:25671;

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • CHCHD10
  • Protein-coding gene in humans

    mitochondrial diseases. CHCHD10 has been known to interact with C1QBP, CLPX, FAF1, RNASEH1, ZNF444, KLF13, and other proteins. ENSG00000250479 GRCh38: Ensembl release

    CHCHD10

    CHCHD10

    CHCHD10

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RNASEH1

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RNASEH1