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Occurrence of a disease with no recognisable pattern
In infectious disease epidemiology, a sporadic disease is an infectious disease which occurs only infrequently, haphazardly, irregularly, or occasionally
Sporadic_disease
Neurodegenerative disease caused by prions
that sporadic CJD can spread among people via normal contact or blood transfusions, although this is possible in variant Creutzfeldt–Jakob disease. Diagnosis
Creutzfeldt–Jakob_disease
Topics referred to by the same term
do not fit into any infinite family of groups Sporadic disease, one with no recognisable pattern Sporadic E propagation, an unusual form of radio propagation
Sporadic
Prion disease of the human brain
treatment-resistant constipation is a highly common clinical feature. The sporadic form of the disease (sFI) often presents atypically compared to the familial form
Fatal_insomnia
Group of neurological disorders affecting motor neurons
Is the disease sporadic or inherited? Is there involvement of the upper motor neurons (UMN), the lower motor neurons (LMN), or both? Sporadic or acquired
Motor_neuron_diseases
Degenerative brain disease caused by prions
Creutzfeldt–Jakob disease. There are three main categories of CJD disease: sporadic CJD, hereditary CJD, and acquired CJD, with variant CJD being in the
Variant Creutzfeldt–Jakob disease
Variant_Creutzfeldt–Jakob_disease
Rare neurodegenerative disease caused by prions
The outbreak likely originated from a villager developing sporadic Creutzfeldt–Jakob disease, which then spread to others via the consumption of the deceased's
Kuru_(disease)
Progressive neurodegenerative disease
not familial, and so they are termed sporadic Alzheimer's disease. Of the cases of sporadic Alzheimer's disease, most are classified as late onset where
Alzheimer's_disease
Rare neurodegenerative disease
genetic cause of familial ALS and are also found in a subset of sporadic cases. Four disease-linked genes are responsible for approximately half of all genetic
ALS
Progressive neurodegenerative disease
"Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort". eBioMedicine. 119 105866
Parkinson's_disease
Group of brain diseases induced by prions
Creutzfeldt–Jakob disease has been divided into four subtypes: sporadic (idiopathic), hereditary, iatrogenic, and variant. These diseases form a spectrum
Transmissible spongiform encephalopathy
Transmissible_spongiform_encephalopathy
Disease of the kidney
Berger's disease is 25% and 73% for non-aggressive Berger's disease.[citation needed] IgA nephropathy (IgAN) is primarily a sporadic disease, with over
IgA_nephropathy
Genetic theory of cancer formation
both as an inherited disease and sporadically. He noted that inherited retinoblastoma occurs at a younger age than the sporadic disease. In addition, the
Two-hit_hypothesis
Prion disease affecting the deer family
transmissible North American form of the disease, but similar to the Norwegian variant of CWD, an atypical or sporadic form which occurs incidentally in individual
Chronic_wasting_disease
Inherited neurodegenerative disorder
Huntington's or Huntington disease (HD), also known as Huntington's chorea, is a fatal neurodegenerative disease that is usually inherited. It typically
Huntington's_disease
Medical condition
lymphadenitis, necrotizing lymphadenitis and Kikuchi-Fujimoto disease (KFD). Kikuchi disease occurs sporadically in people with no family history of the condition
Kikuchi_disease
Dementia involving the frontal or temporal lobes
conditions; this is known as sporadic FTD. While environmental causes and unidentified gene variants are suspected causes of sporadic FTD, research in this area
Frontotemporal_dementia
Prion disease of mink
Transmissible mink encephalopathy (TME) is a rare sporadic disease that affects the central nervous system of ranch-raised adult mink. It is a transmissible
Transmissible mink encephalopathy
Transmissible_mink_encephalopathy
Medical condition
prevent early-onset disease in these contacts and usually is not recommended following sporadic cases of invasive meningococcal disease. Unlike developed
Meningococcal_disease
Disorders of adaptive immune system
An autoimmune disease is a condition causing disease that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets
Autoimmune_disease
Infection transmitted through human sexual behavior
transmitted infection (STI), also known as a sexually transmitted disease (STD) or venereal disease (VD), is an infection that is spread by sexual activity, especially
Sexually transmitted infection
Sexually_transmitted_infection
Invasion of an organism's body by pathogenic agents
such as gender and race. Researchers also may assess whether a disease outbreak is sporadic, or just an occasional occurrence; endemic, with a steady level
Infection
Disease caused by Yersinia pestis bacterium
Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness, headache and black lips. Usually, this begins
Plague_(disease)
Alzheimer's disease developed before the age of 65
cases.[citation needed] The rest are sporadic and not based on genetic mutations. Early-onset Alzheimer's disease strikes earlier in life, defined as before
Early-onset Alzheimer's disease
Early-onset_Alzheimer's_disease
Pathogenic type of misfolded protein
diseases, which are fatal and transmissible neurodegenerative diseases affecting animals, including humans. These proteins can misfold sporadically,
Prion
Birth defect in which the intestine lacks certain nerves
with Hirschsprung's disease[citation needed] The RET proto-oncogene accounts for the highest proportion of both familial and sporadic cases, with a wide
Hirschsprung's_disease
Medical condition caused by bacterial toxins
year. TSS was considered a sporadic disease that occurred in immunocompromised people. It was not a more well-known disease until the 1980s, when high-absorbency
Toxic_shock_syndrome
Group of diseases involving cell growth
Cancer is a group of diseases involving uncontrolled cell growth typically resulting in tumors with the potential to invade or spread to other parts of
Cancer
Inflammatory muscle disease in older adults
(sometimes called sporadic inclusion body myositis, sIBM) is the most common inflammatory muscle disease in older adults. The disease is characterized
Inclusion_body_myositis
Elimination of a disease from all hosts
these diseases remained at a low prevalence in parts of Asia, Africa and the Americas with sporadic outbreaks. In 2012, the WHO targeted the disease for
Eradication of infectious diseases
Eradication_of_infectious_diseases
Medical condition
first described in 1962 in secluded mountainous regions of Tanzania, with sporadic outbreaks in the decades since in South Sudan, Uganda, and again in Sudan
Nodding_disease
Species of bacterium
that were mainly isolated from watermelon.[citation needed] BFB is a sporadic disease but under favorable environment, it becomes devastating and may cause
Acidovorax_citrulli
Disease characterized by constriction of brain arteries
moyamoya disease, short stature, hypergonadotropic hypogonadism, and facial dysmorphism, and linked to q25.3, on chromosome 17. Both familial and sporadic moyamoya
Moyamoya_disease
Medical condition
Sickle cell disease (SCD), also simply called sickle cell, is a group of inherited hemoglobin-related blood disorders. Sickle cell disease is caused by
Sickle_cell_disease
Medical condition
study, a genetic cause was suspected. Some have suggested the disease may be a sporadic form of Gerstmann–Sträussler–Scheinker syndrome (GSS). The inability
Variably protease-sensitive prionopathy
Variably_protease-sensitive_prionopathy
Infectious disease
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever
Influenza
Disease in which fibrous connective tissue turns into bone
also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease. Fibrous connective tissue
Fibrodysplasia ossificans progressiva
Fibrodysplasia_ossificans_progressiva
Progressive cystic lung disease
progressive and systemic disease that typically results in cystic lung destruction. It predominantly affects women. The term sporadic LAM is used for patients
Lymphangioleiomyomatosis
Central nervous system disease
in some cases of the disease, and a mutation in chromosome 9 (C9orf72) is thought to be the most common known cause of sporadic ALS. Early diagnosis of
Neurodegenerative_disease
Region with a lack of blood flow due to vein malformation
Somatic mutations in MAP3K3 and PIK3CA have been identified in sporadic lesions; familial disease arises from germline mutations in the CCM genes. In 2025,
Cavernous_hemangioma
Type of blood cancer
development of Waldenström macroglobulinemia. Although believed to be a sporadic disease, studies have shown increased susceptibility within families, indicating
Waldenström_macroglobulinemia
Genetic disorder
tumours associated with VHL disease can be found sporadically, at least two tumours must be identified to diagnose VHL disease in a person without a family
Von_Hippel–Lindau_disease
Red rash due to infection with parvovirus B19
Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, is a common and contagious disease caused by infection with parvovirus B19
Fifth_disease
Infectious disease readily spread by pathogen transmission
A contagious disease is an infectious disease that can be spread rapidly in several ways, including direct contact, indirect contact, and droplet contact
Contagious_disease
Malaria-like parasitic disease
the Northeastern and Midwestern United States and parts of Europe, and sporadic throughout the rest of the world. It occurs in warm weather. People can
Babesiosis
Disease transmission by airborne particles
transmission is transmission of an infectious disease through small particles suspended in the air. Infectious diseases capable of airborne transmission include
Airborne_transmission
Disease which is constantly present in an area
that disease. Hypoendemic An endemic disease with a low rate of infection. Typhoid fever is a hypoendemic disease in the US. Sporadic A disease that appears
Endemic_(epidemiology)
Viral disease affecting parrots
are likely susceptible to sporadic spill-over infection, and there is unpublished evidence of BFDV-associated feather disease in the laughing kookaburra
Psittacine beak and feather disease
Psittacine_beak_and_feather_disease
Disease caused by agents transmitted by water
Waterborne diseases are diseases caused by pathogenic micro-organisms, such as bacteria, viruses, protozoa, and parasitic worms, that are transmitted
Waterborne_disease
Medical condition
first symptom of the disease, and it is noteworthy that some FTDP-17 patients have been misdiagnosed with Parkinson's disease or sporadic progressive supranuclear
Frontotemporal dementia and parkinsonism linked to chromosome 17
Frontotemporal_dementia_and_parkinsonism_linked_to_chromosome_17
Group of disorders
Epstein–Barr virus–associated lymphoproliferative diseases (also abbreviated EBV-associated lymphoproliferative diseases or EBV+ LPD) are a group of disorders in
Epstein–Barr virus–associated lymphoproliferative diseases
Epstein–Barr_virus–associated_lymphoproliferative_diseases
Metabolic disease involving abnormal deposited amyloid proteins
there is normally an early age of onset. Half of amyloid-related diseases are sporadic and have a late age of onset – in these cases, the protein aggregation
Amyloidosis
Rare neuromuscular disease
Sporadic late-onset nemaline myopathy, or SLONM, is a very rare disease, one of the nemaline myopathies, causing loss of muscle bulk and weakness in the
Sporadic late-onset nemaline myopathy
Sporadic_late-onset_nemaline_myopathy
First documented patient in the population of an epidemiological investigation
Retrieved 18 November 2017. "Sporadic STEC O157 Infection: Secondary Household Transmission in Wales". CDC.gov. Centers for Disease Control and Prevention,
Index_case
Abnormal connection between arteries and veins, bypassing the capillaries
needed] Bleeding (45% of cases) "parkinsonism" 4 symptoms in Parkinson's disease Acute onset of severe headache. May be described as the worst headache
Arteriovenous_malformation
Viral disease
typically affected by EEE. The first human case in Michigan was in 1980. Sporadic disease outbreaks have occurred in eastern Connecticut and Rhode Island since
Eastern_equine_encephalitis
Illness from eating spoiled or contaminated food
Foodborne illness (also known as foodborne disease and food poisoning) is any illness resulting from the contamination of food by pathogenic bacteria
Foodborne_illness
Medical condition
A blood-borne disease is a disease that can be spread through contamination by blood and other body fluids. Blood can contain pathogens of various types
Blood-borne_disease
Viral disease caused by the varicella zoster virus
previously thought. For example, sporadic meningoencephalitis (ME) caused by varicella-zoster was regarded as a rare disease, mostly related to childhood
Shingles
Abscess adjacent to the anus
are sporadic, though there are certain situations which elevate the risk for developing the disease, such as diabetes mellitus, Crohn's disease, chronic
Anorectal_abscess
Vascular anomaly
PMID 19588535. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 582–3. ISBN 0-7216-2921-0
Port-wine_stain
Group of disorders of bone and cartilage development
growths projecting from the surfaces of bones. Maffucci syndrome is a sporadic disease characterized by the presence of multiple enchondromas associated with
Osteochondrodysplasia
Viral disease caused by herpes simplex viruses
occur before the blisters appear. Herpes cycles between periods of active disease followed by periods without symptoms. The first episode is often more severe
Herpes
Infection caused by the chikungunya virus
aegypti to maintain its sylvatic cycle. Prior to this, the disease may have caused sporadic epidemics in other regions, which had been incorrectly ascribed
Chikungunya
Rare genetic disorder of the white matter of the brain
the disease has a 50% chance of inheriting the condition, if the parent is heterozygotic. However, most cases arise de novo as the result of sporadic mutations
Alexander_disease
Medical condition
of muscle function. PMA is classified among motor neuron diseases (MND) and it sporadically appears during adulthood. It is speculated that about 2.5%-11%
Progressive_muscular_atrophy
Agent that carries and transmits pathogens
In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen such as a parasite or microbe, to another living
Disease_vector
Medical condition
Systemic-onset juvenile idiopathic arthritis (sJIA), also known as Still disease, Still's disease, and systemic juvenile idiopathic arthritis, is a subtype of juvenile
Systemic-onset juvenile idiopathic arthritis
Systemic-onset_juvenile_idiopathic_arthritis
Spherical inclusion commonly found in damaged neurons
E (March–April 2003). "Staging of brain pathology related to sporadic Parkinson's disease". Neurobiology of Aging. 24 (2): 197–211. doi:10.1016/S0197-4580(02)00065-9
Lewy_body
Disease caused by the bacteria Salmonella typhi
Typhoid fever, also known as typhoid, is an orally contracted disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella Typhi
Typhoid_fever
Genetic condition causing non-cancerous tumours
through routine medical care. The prevalence of the disease is estimated to be 7 to 12 in 100,000. The disease is often abbreviated to tuberous sclerosis, which
Tuberous_sclerosis
Placeholder infectious disease name from the World Health Organization
Disease X is a placeholder name that was adopted by the World Health Organization (WHO) in February 2018 on their shortlist of blueprint priority diseases
Disease_X
Amphibian disease
Old World is also at risk of the disease arriving within the coming years. The fungus is capable of causing sporadic deaths in some amphibian populations
Chytridiomycosis
Medical condition
reddishness. In addition to the skin lesions, chronic liver disease is very common in patients with sporadic PCT. This involves hepatic fibrosis (scarring of the
Porphyria_cutanea_tarda
Medical condition
Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. They are caused by infection with
Tick-borne_disease
Factors causing Parkinson's disease
of developing either familial or sporadic PD. More penetrant PD mutations with a higher risk of developing the disease, tend to be rare but are often associated
Causes_of_Parkinson's_disease
Passing of a pathogen from one organism to another
biology, transmission is the passing of a pathogen causing communicable disease from an infected host individual or group to a particular individual or
Pathogen_transmission
Infection by a pathogen of non-human origin
zoonosis (/zoʊˈɒnəsɪs, ˌzoʊəˈnoʊsɪs/ ; pl.: zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as
Zoonosis
Group of genetic disorders resulting in fragile bones
/ˌɒstioʊˈdʒɛnəsɪs ˌɪmpɜːrˈfɛktə/; OI), colloquially known as brittle bone disease, is a group of genetic disorders that all result in bones that break easily
Osteogenesis_imperfecta
Disease transmission via pathogens from fecal particles
transmission of a disease wherein pathogens in fecal particles pass from one person to the mouth of another person. Main causes of fecal–oral disease transmission
Fecal–oral_route
Cancer of cattle
specific causative agent has yet been discovered, as the disease appears to occur sporadically in cattle population, as the name suggests. This condition
Sporadic_bovine_lymphosarcoma
Medical condition
Sporadic hemiplegic migraine (SHM) is a form of hemiplegic migraine headache isolated cases of which are observed. It is a rare disease. It is considered
Sporadic_hemiplegic_migraine
Severe lung infection
soon as possible. So far, they have done exactly that. There have been sporadic cases reported around the country in the last few years so the authorities
Pneumonic_plague
Medical condition
lower extremity. It belongs to the PIK3CA-related overgrowth spectrum of diseases which are caused by mutations in the PIK3CA gene. The birth defect is diagnosed
Klippel–Trénaunay_syndrome
pathogens, vectors and disease hosts interact. These changes are altering the geographic ranges and seasonal activity of disease-carrying organisms such
Climate change and infectious diseases
Climate_change_and_infectious_diseases
Fungal infection of the lungs
Histoplasma capsulatum. Symptoms of this infection vary greatly, but the disease affects primarily the lungs. Occasionally, other organs are affected; called
Histoplasmosis
Medical condition
since a positive family history or consanguinity has been noted. However, sporadic cases also have been reported. Ongoing research has identified some implicated
XX_gonadal_dysgenesis
New or rapidly increasing disease
An emerging infectious disease (EID) refer to infectious diseases that have either newly appeared in a population or have existed but are rapidly increasing
Emerging_infectious_disease
Medical condition
Ollier disease is a rare sporadic nonhereditary skeletal disorder in which typically benign cartilaginous tumors (enchondromas) develop near the growth
Ollier_disease
Infectious disease = Invasion of an organism's body by pathogenic agents
are located and spread across different regions. Sporadic – scattered, irregular occurrence of disease cases without any recognizable pattern in space
Outline of infectious disease concepts
Outline_of_infectious_disease_concepts
Congenital abnormality involving a single higher shoulder blade
properly from the neck to its final position. The majority of cases are sporadic, with very few having autosomal dominant inheritance. The deformity is
Sprengel's_deformity
Time between infection and the onset of disease symptoms
on the disease. A person may carry a disease, such as Streptococcus in the throat, without exhibiting any symptoms. Depending on the disease, the person
Incubation_period
Obstruction of the lungs' small airways (bronchioles) due to inflammation
obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a disease that results in obstruction of the smallest airways of the lungs (bronchioles)
Bronchiolitis_obliterans
beginning to rebound, although it continues to be confronted by minor and sporadic disease outbreaks. Domestic grain production is increasing, and the government
Economy_of_Georgia_(country)
Non-living object capable of carrying infectious agents
infectious agents (such as pathogenic bacteria, viruses or fungi), can transfer disease to a new host. A fomite is any inanimate object (also called passive vector)
Fomite
Disease outbreaks in New York City, United States
in Patients with Sporadic Community‐Acquired Legionellosis: An International Collaborative Survey". The Journal of Infectious Diseases. 186 (1): 127–8
2015 Bronx Legionnaires' disease outbreaks
2015_Bronx_Legionnaires'_disease_outbreaks
Neurodegenerative disorder
as Parkinson's disease. However, those with MSA generally show little response to the dopamine agonists used to treat Parkinson's disease and only about
Multiple_system_atrophy
Sudden increase in occurrences of a disease
In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season
Disease_outbreak
Epidemiological studies have shown lower age-related prevalence of Parkinson's disease in South Asians, with the rate of prevalence being around 52.7 per 100
Parkinson's disease in South Asians
Parkinson's_disease_in_South_Asians
Condition involving an enlarged, ineffective heart
pain or fainting. Complications can include heart failure, heart valve disease, or an irregular heartbeat. Causes include genetics, alcohol, cocaine,
Dilated_cardiomyopathy
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SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
SPORADIC DISEASE
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