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Rare genetic disorder of the white matter of the brain
Alexander disease is a very rare autosomal dominant leukodystrophy, which are neurological conditions caused by anomalies in the myelin which protects
Alexander_disease
Medication
the brand name Zanvastro, is a medication used for the treatment of Alexander disease. It is a glial fibrillary acidic protein (GFAP)-directed antisense
Zilganersen
Death of the Macedonian king in 323 BC
infectious disease, dying on June 10, 323 BC at the age of 32. Some accounts propose causes of Alexander's death such as alcoholic liver disease, and poisoning
Death_of_Alexander_the_Great
Abnormally large head size
leukodystrophies (brain white matter degeneration) such as Alexander disease, Canavan disease, and megalencephalic leukoencephalopathy with subcortical
Macrocephaly
Group of disorders characterised by degeneration of white matter in the brain
leukodystrophy (MLD), (2) Krabbe disease, (3) X-Linked adrenoleukodystrophy (ALD), (4) Canavan disease, and (5) Alexander disease. Each type of leukodystrophy
Leukodystrophy
Sign of a few neurodegenerative disorders
astrocytoma), and rarely in lysosomal storage diseases such as fucosidosis. They may be seen in Alexander disease. Rosenthal fibers can also be seen in craniopharyngioma
Rosenthal_fiber
Topics referred to by the same term
drink made with Cognac Alexander Technique, a method of removing muscular tension Alexander disease, a very rare disease Alexander violin, a string instrument
Alexander_(disambiguation)
Type III intermediate filament protein
up-regulation of GFAP. Another condition directly related to GFAP is Alexander disease, a rare genetic disorder. Its symptoms include mental and physical
Glial fibrillary acidic protein
Glial_fibrillary_acidic_protein
United States government public health agency
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under
Centers for Disease Control and Prevention
Centers_for_Disease_Control_and_Prevention
Autoimmune disease
Multiple sclerosis (MS) is a chronic and neurodegenerative autoimmune disease in which the immune system attacks myelin, the insulating cover of nerve
Multiple_sclerosis
Progressive neurodegenerative disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor and non-motor
Parkinson's_disease
Diseases named after a person
An eponymous disease is a disease, disorder, condition, or syndrome named: usually, after the physician or health care professional who first identified
List_of_eponymous_diseases
Diseases caused by abnormal protein structure
-pathy [suff. disease]; proteinopathies pl.; proteinopathic adj), or proteopathy, protein conformational disorder, or protein misfolding disease, is a class
Proteinopathy
Medical condition
acquired insult.)[citation needed] Examples include: Alexander disease Canavan disease Krabbe disease leukoencephalopathy with vanishing white matter megalencephalic
Hereditary CNS demyelinating disease
Hereditary_CNS_demyelinating_disease
Postural awareness technique
Alexander technique may be helpful for long-term back pain and for long-term neck pain, and that it could help people cope with Parkinson's disease.
Alexander_technique
Rare neurodegenerative disease
lateral sclerosis (ALS), also known as motor neuron disease (MND), Lou Gehrig's disease or Charcot's disease (English: /ʃɑːrˈkoʊ/ shar-KOH, French: [ʃaʁko])
ALS
Inherited neurodegenerative disorder
Huntington's or Huntington disease (HD), also known as Huntington's chorea, is a fatal neurodegenerative disease that is usually inherited. It typically
Huntington's_disease
Akinetopsia Alexander Disease Alien hand syndrome Allan–Herndon–Dudley syndrome Alternating hemiplegia of childhood Alzheimer's disease Amaurosis fugax
List of neurological conditions and disorders
List_of_neurological_conditions_and_disorders
Form of treatment for genetic disorders and other illnesses
investigated in disease models for Alexander disease, ATXN2 (gene) and FUS (gene) amyotrophic lateral sclerosis, Angelman syndrome, Lafora disease, lymphoma
Antisense_therapy
King of Macedon from 336 to 323 BC
S; Calisher, Charles H (2003). "Alexander the Great and West Nile Virus Encephalitis". Emerging Infectious Diseases. 9 (12): 1599–1603. doi:10.3201/eid0912
Alexander_the_Great
Progressive neurodegenerative disease
Alzheimer's disease (AD) is a neurodegenerative disease and is the most common cause of dementia, accounting for around 60–70% of cases. The most common
Alzheimer's_disease
Common human disease caused by a group of viruses
Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of enteroviruses. It typically begins with a fever and feeling generally
Hand,_foot,_and_mouth_disease
Reduction of blood flow to the heart
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of heart disease involving the reduction
Coronary_artery_disease
Aldosteronism, glucocorticoid-remediable; 103900; CYP11B1 Alexander disease; 203450; GFAP Alexander disease; 203450; NDUFV1 Alkaptonuria; 203500; HGD Allan–Herndon–Dudley
List_of_OMIM_disorder_codes
Scottish physician and microbiologist (1881–1955)
B. Lee (2004). "Sir Alexander Fleming: Scottish researcher who discovered penicillin". Seminars in Pediatric Infectious Diseases. 15 (1): 58–64. doi:10
Alexander_Fleming
Medical condition
Adult polyglucosan body disease (APBD) is a rare monogenic glycogen storage disorder (GSD type IV) caused by an inborn error of metabolism. Symptoms can
Adult polyglucosan body disease
Adult_polyglucosan_body_disease
type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the
List_of_genetic_disorders
Contagious disease caused by SARS-CoV-2
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. Starting in January 2020, the disease spread worldwide
COVID-19
Emperor of Russia from 1881 to 1894
this incident.[self-published source] In 1894, Alexander III became ill with terminal kidney disease (nephritis). His first cousin, Queen Olga of Greece
Alexander_III_of_Russia
cirrhosis Aldolase A deficiency Aldred syndrome Aleukemic leukemia cutis Alexander disease Alexia (acquired dyslexia) Alien hand syndrome Alkaptonuria Allain–Babin–Demarquez
List_of_diseases_(A)
American infectious disease physician
Barbara Dudley Alexander is an American infectious disease physician. She is a professor of medicine and pathology at the Duke University School of Medicine
Barbara_Dudley_Alexander
Stem cell biologist
Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease". Cell Stem Cell. 23 (2): 239–251.e6. doi:10.1016/j.stem.2018.07.009
Valentina_Fossati
Biotechnology company
treatment for a rare neurological condition called Alexander disease (AxD). Meanwhile, its potential heart disease medication, Wainua did not outperform placebos
Ionis_Pharmaceuticals
American epidemiologist (1910–1993)
lead the US Army's Commission on Acute Respiratory Diseases during World War II, he recruited Alexander Langmuir to serve at Fort Bragg in North Carolina
Alexander_Langmuir
Invasion of an organism's body by pathogenic agents
toxins they produce. An infectious disease is an illness resulting from an infection, and some infectious diseases are also communicable (transmissible)
Infection
British neurologist
research of hepatolenticular degeneration led the disease to be named after him as Wilson's disease. He was the father of British Assyriologist James
Samuel Alexander Kinnier Wilson
Samuel_Alexander_Kinnier_Wilson
Medical research and advocacy organization
Projects. Alexander disease Canavan disease Krabbe disease Metachromatic leukodystrophy Pelizaeus–Merzbacher disease Phenylketonuria Refsum disease Transverse
The_Myelin_Project
Abnormal growth of scar tissue within the penis
Peyronie's disease (PD) is a benign, acquired penile connective tissue disease characterized by the occurrence of fibrotic plaques within the tunica albuginea—the
Peyronie's_disease
Grand Duke of Russia
Grand Duke Alexander Alexandrovich of Russia (Russian: Александр Александрович; 7 June 1869 – 2 May 1870) was the second son of the Tsesarevich and Tsesarevna
Grand Duke Alexander Alexandrovich of Russia
Grand_Duke_Alexander_Alexandrovich_of_Russia
Prevailing theory about diseases
The germ theory of disease is the currently accepted scientific theory explaining the cause of infectious diseases. It states that microorganisms known
Germ_theory_of_disease
Sexually transmitted infection
"the great imitator", because it may cause symptoms similar to many other diseases. Syphilis is most commonly spread through sexual activity. It may also
Syphilis
Genetic multisystem copper-transport disease
Wilson's disease (also called hepatolenticular degeneration) is a genetic disorder characterized by the excess build-up of copper in the body. Symptoms
Wilson's_disease
Network of filamentous proteins that forms the internal framework of cells
issues such as premature aging, desmin mutations compromising organs, Alexander Disease, and muscular dystrophy. Different intermediate filaments are: made
Cytoskeleton
(see Artery of Adamkiewicz). W. Stewart Alexander, contemporary British pathologist (see Alexander disease). Dame Ingrid Allen, Northern Irish neuropathologist
List_of_pathologists
Common viral infectious disease
infected by the virus as children, when the disease produces few or no symptoms. In young adults, the disease often results in fever, sore throat, enlarged
Infectious_mononucleosis
American Founding Father (died 1804)
Alexander Hamilton (January 11, 1755, or 1757 – July 12, 1804) was an American military officer, statesman, and Founding Father who served as the first
Alexander_Hamilton
American author (1954–2026)
His book subjects included the Philadelphia Zoo, his family history, Alexander Hamilton's duel with Aaron Burr, railroad companies competing to link
John_Sedgwick_(author)
Medical conditions that cannot transmit from one individual to another
non-communicable disease (NCD) is a disease that is not transmissible directly from one person to another. NCDs include Parkinson's disease, autoimmune diseases, strokes
Non-communicable_disease
Roman emperor from 222 to 235
Marcus Aurelius Severus Alexander (1 October 208 AD – March 235 AD), also known as Alexander Severus, was Roman emperor from 222 until 235 AD. He was the
Severus_Alexander
Difference in coloration, usually of the iris but also of hair or skin
pigment). It may be inherited or caused by genetic mosaicism, chimerism, disease, or injury. It occurs in humans and certain breeds of domesticated animals
Heterochromia
Group of lymphoproliferative disorders
Whether Castleman disease should be considered an autoimmune disease, cancer, or infectious disease is currently unknown. Castleman disease includes at least
Castleman_disease
Emperor of Russia from 1801 to 1825
Alexander I of Russia (Russian: Александр I Павлович, romanized: Aleksandr I Pavlovich, IPA: [ɐlʲɪkˈsandr ˈpavləvʲɪtɕ]; 23 December [O.S. 12 December]
Alexander_I_of_Russia
Inventor of the telephone (1847–1922)
Alexander Graham Bell (/ˈɡreɪ.əm/ ; born Alexander Bell; March 3, 1847 – August 2, 1922) was a Scottish-born Canadian-American inventor, scientist, and
Alexander_Graham_Bell
British doctor (1779–1866)
the mental disease; later extended to cover diseases connected with the nervous system. Wikimedia Commons has media related to Alexander Morison. Lee
Alexander_Morison
Human chromosome
The following diseases are related to genes on chromosome 17: 17q12 microdeletion syndrome Koolen–de Vries syndrome Alexander disease Andersen–Tawil
Chromosome_17
Metabolic disease involving abnormal deposited amyloid proteins
Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs
Amyloidosis
American football player (1970–2010)
persistent pain in his feet, before his diagnosis. The disease was discovered after Alexander had bloodwork in Costa Rica while on a golfing vacation
Elijah_Alexander
Birth defect in which the intestine lacks certain nerves
Hirschsprung's disease (HD or HSCR) is a birth defect in which nerves are missing from parts of the intestine. The most prominent symptom is constipation
Hirschsprung's_disease
Statistical geneticist
Alexander (Sasha) Gusev is a research scientist and associate professor of medicine at Harvard Medical School and the Dana Farber Cancer Institute. At
Alexander_Gusev_(professor)
English consultant obstetrician and gynaecologist (1908–2001)
research on the use of penicillin in the treatment of venereal disease with Sir Alexander Fleming in London. He was the father of television news journalist
Jack_Suchet
Infectious diseases with high prevalence are separately (sometimes in addition to their epidemics), such as malaria, which may have killed 50–60 million
List of epidemics and pandemics
List_of_epidemics_and_pandemics
American gynecologist and sculptor (1837–1900)
Generationi Inservientibus (in Latin). Leiden. Skene, Alexander J. C. (1890) [1888]. Treatise on the Diseases of Women: For the Use of Students and Practitioners
Alexander_Skene
Type of arthritis of the spine
Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. The term comes from the Greek ankylos meaning
Ankylosing_spondylitis
Health problem from genome abnormalities
inherited from one or both parents, it is also classified as a hereditary disease. Some disorders are caused by a mutation on the X chromosome and have X-linked
Genetic_disorder
British physician
George Alexander Sutherland CBE FRCP (11 April 1861, Old Machar, Aberdeen – 10 October 1939, Amersham) was a British physician, specializing in paediatrics
George_Alexander_Sutherland
Human retrovirus, cause of AIDS
name for the disease, often referring to it by way of the diseases that were associated with it, for example, lymphadenopathy, the disease after which
HIV
Type of brain cell
encephalitis, Alexander disease, and amyotrophic lateral sclerosis. Studies have shown that astrocytes may be implied in neurodegenerative diseases, such as
Astrocyte
Rise of salaries in jobs that have seen little rise of productivity
In economics, the Baumol effect, or Baumol's cost disease, first described by William J. Baumol and William G. Bowen in the 1960s, is the tendency for
Baumol_effect
Infectious disease caused by poliovirus
commonly shortened to polio, is a vaccine-preventable infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic;
Polio
Tuberculosis of the spine
Pott's disease (also known as tuberculous spondylitis) is tuberculosis of the spine, usually due to hematogenous spread from other sites, often the lungs
Pott's_disease
Capacity of an organism to defend itself against pathological processes
Disease resistance is the ability to prevent or reduce the presence of diseases in otherwise susceptible hosts. It can arise from genetic or environmental
Disease_resistance
Genetic disorder in European royalty
Victoria's youngest son, Prince Leopold, Duke of Albany, also had the disease, though none of her three elder sons did. Tests on the remains of the Romanov
Haemophilia in European royalty
Haemophilia_in_European_royalty
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range
List_of_autoimmune_diseases
leukodystrophy Adrenoleukodystrophy Krabbe disease Alexander disease Canavan disease Pelizaeus–Merzbacher disease The Stennis Foundation's home page v t e
The_Stennis_Foundation
Greek research organization
The Biomedical Sciences Research Center "Alexander Fleming" (BSRC Al. Fleming, Greek: Ερευνητικό Κέντρο Βιοϊατρικών Επιστημών "Αλέξανδρος Φλέμινγκ") is
Alexander Fleming Biomedical Sciences Research Center
Alexander_Fleming_Biomedical_Sciences_Research_Center
English actor (1923–2009)
Terence Joseph Alexander (11 March 1923 – 28 May 2009) was an English film and television actor, best known for his role as Charlie Hungerford in the
Terence_Alexander
American actor (born 1959)
1989. Alexander was the national spokesman for the Scleroderma Foundation, a leading organization dedicated to raising awareness of the disease and assisting
Jason_Alexander
American actor (born 1958)
Alexander Rae Baldwin III (born April 3, 1958) is an American actor and film producer. He is known for his leading and supporting roles in a variety of
Alec_Baldwin
Bacteria harming plants, including crops
sap-feeding insects such as sharpshooters and spittlebugs. Many plant diseases are due to infections of X. fastidiosa, including bacterial leaf scorch
Xylella_fastidiosa
English poet (1688–1744)
Alexander Pope (21 May 1688 O.S. – 30 May 1744) was an English poet, translator, and satirist of the Enlightenment era who is considered one of the most
Alexander_Pope
Scottish physician and writer (1853–1924)
S2CID 220025450. "Reviewed Work: Uric Acid As A Factor In The Causation Of Disease by Alexander Haig". The British Medical Journal. 2 (2483): 263. 1908. Kiple, Kenneth
Alexander_Haig_(physician)
Condition of impaired digestion
Peptic Ulcer Disease and H. pylori Infection". American Family Physician. 91 (4): 236–242. ISSN 1532-0650. PMID 25955624. Ford, Alexander C.; Tsipotis
Indigestion
Medical condition
Idiopathic multicentric Castleman disease (iMCD) is a subtype of Castleman disease (also known as giant lymph node hyperplasia, lymphoid hamartoma, or
Idiopathic multicentric Castleman disease
Idiopathic_multicentric_Castleman_disease
and people across political and geographic boundaries, allows infectious diseases to rapidly spread around the world, while also allowing the alleviation
Globalization_and_disease
Contagious viral avian disease
Virulent Newcastle disease (VND), formerly exotic Newcastle disease, is a contagious viral avian disease affecting many domestic and wild bird species;
Virulent_Newcastle_disease
Infectious disease = Invasion of an organism's body by pathogenic agents
as an overview of and topical guide to concepts related to infectious diseases in humans. Infection – Subsequent to their transmission via environment
Outline of infectious disease concepts
Outline_of_infectious_disease_concepts
Ancient Greek military campaign in Indus Valley
provide remedies for snake-bites to Alexander, the king gathered Indian healers who were also able to cure other diseases and painful conditions. The Greek
Indian campaign of Alexander the Great
Indian_campaign_of_Alexander_the_Great
Human eye disease causing full or partial blindness
Coats' disease is a rare congenital, nonhereditary eye disorder, causing full or partial blindness, characterized by abnormal development of blood vessels
Coats'_disease
Increase in astrocytes in response to brain injury
syndrome autoantibody destruction of astrocytes causes seizures In Alexander's disease, a dominant, gain-of-function mutation of the gene encoding GFAP
Astrogliosis
Medical condition
Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland. The thyroid gland is located at the front of the
Thyroid_disease
Medical condition of the eye
Wagner's disease is a familial disease of the eye that can cause reduced visual acuity. Wagner's disease was originally described in 1938. This disorder
Wagner's_disease
Infectious disease
as the "white death", or historically as consumption, is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis
Tuberculosis
American academic (1920–2009)
unfinished computer-generated film "The Works". Alexander Schure died from complications of Alzheimer's disease on Long Island on October 29, 2009, at the
Alexander_Schure
Disease of walnut trees
Thousand cankers disease (TCD) is a recently recognized disease of certain walnuts (Juglans spp.). The disease results from the combined activity of the
Thousand_cankers_disease
Childhood spinal disorder
Copenhagen disease, sometimes known as Copenhagen syndrome or progressive non-infectious anterior vertebral fusion (PAVF), is a very rare spinal disorder
Copenhagen_disease
Fatal childhood genetic condition
Batten disease is a fatal disease of the nervous system that typically begins in childhood. Onset of symptoms is usually between 5 and 10 years of age
Batten_disease
Infectious disease
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever
Influenza
2021 studio album by Nas
King's Disease II is the thirteenth studio album by American rapper Nas. It was released on August 6, 2021, through Mass Appeal Records. Serving as a
King's_Disease_II
American infectious disease specialist
Nicole Alexander-Scott is an American infectious disease specialist who served as Director of the Rhode Island Department of Health from April 2015 to
Nicole_Alexander-Scott
American medical doctor (1940–2020)
his MD from Johns Hopkins. On February 16, 2020, Alexander died after having battled Alzheimer's disease for several years. Who's Who in America 1986-1987
Duane_Alexander
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ALEXANDER DISEASE
ALEXANDER DISEASE
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