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Family of intracellular transcription factors
Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects
STAT_protein
Biological signaling pathway h
The JAK-STAT signaling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell
JAK-STAT_signaling_pathway
Topics referred to by the same term
attributes of an inode Stat (TV series), an American sitcom that aired in 1991 Stat (website), a health-oriented news website STAT protein, a signal transducer
STAT
Genetic abnormality in leukemia cancer cells
JAK proteins naturally phosphorylate each other, prompting a STAT protein to bind to the JAK tyrosine phosphorylated domain. The STAT protein is in
Philadelphia_chromosome
Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals. PIAS proteins
Protein inhibitor of activated STAT
Protein_inhibitor_of_activated_STAT
Drug class
STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors
STAT_inhibitors
Protein-coding gene in humans
encoded by the STAT3 gene. It is a member of the STAT protein family. STAT3 is a member of the STAT protein family. In response to cytokines and growth factors
STAT3
InterPro Family
more commonly referred to as the JAK-STAT pathway. In the JAK-STAT pathway, activated JAK1 and JAK2 proteins regulate the phosphorylation of tyrosine
Interferon_gamma
Protein
(SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known
SOCS3
Transcription factor and coding gene in humans
humans is encoded by the STAT1 gene. It is a member of the STAT protein family. All STAT molecules are phosphorylated by receptor associated kinases
STAT1
Non-receptor tyrosine kinase and coding gene in humans
Horsch K, Daly JM, Hynes NE (June 1999). "ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases". The Journal of
Janus_kinase_2
Protein-coding gene in the species Homo sapiens
Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene. Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent
Poly(ADP-ribose) polymerase family member 14
Poly(ADP-ribose)_polymerase_family_member_14
Protein-coding gene in the species Homo sapiens
transcription factor belonging to the STAT protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6. STAT proteins are key activators of gene
STAT4
Hormone that inhibits hunger
λεπτός leptos, "thin" or "light" or "small"), also known as obese protein, is a protein hormone predominantly made by adipocytes (cells of adipose tissue)
Leptin
Protein that stimulates red blood cell production
often be detected in blood, due to slight differences from the endogenous protein; for example, in features of posttranslational modification. EPO is highly
Erythropoietin
Mammalian protein found in Homo sapiens
activation of the JAK/STAT (Janus kinase/signal transducer and activator of transcription) and MAPK (mitogen activated protein kinase) cascades.[citation
Leukemia_inhibitory_factor
Mammalian protein found in Homo sapiens
Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein is also known as IL-23p19. It is one of the two subunits
Interleukin_23_subunit_alpha
Form of localized cell signaling
attract STAT proteins. The STAT proteins dimerize and enter the nucleus to act as transcription factors to alter gene expression. In particular, the STATs transcribe
Paracrine_signaling
Mammalian protein found in Homo sapiens
members of the family Signal Transducer and Activator of Transcription (STAT protein); phosphorylated STAT1 and STAT2 bind IRF9 forming a complex named "IFN-Stimulated
IFNA2
Protein-coding gene in the species Homo sapiens
Interleukin-31 receptor A is a protein that in humans is encoded by the IL31RA gene. IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor
IL31RA
Protein-coding gene in the species Homo sapiens
complete genome data are available. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS)
Suppressor of cytokine signaling 1
Suppressor_of_cytokine_signaling_1
Cytokine with structural similarity to Interleukin-2
Phosphorylation STATs form transcription factors and activate transcription of appropriate genes. The β chain of IL-15R recruits and also activates protein tyrosine
Interleukin_15
Protein-coding gene in Homo sapiens
transcription 2 is a protein that in humans is encoded by the STAT2 gene. It is a member of the STAT protein family. This protein is critical to the biological
STAT2
Protein-coding gene in the species Homo sapiens
SUMO-protein ligase PIAS4 is one of several protein inhibitor of activated STAT (PIAS) proteins. It is also known as a protein inhibitor of activated STAT
PIAS4
Mammalian protein found in humans
other proteins" signal. The proteins expressed by means of the three pathways include bcl-6 (the PI3K/Akt/mTOR pathway), CD25 & prdm-1 (the JAK-STAT pathway)
Interleukin_2
Enzyme that adds phosphate groups to other proteins
is Janus kinase (JAK), many of whose effects are mediated by STAT proteins. (See JAK-STAT pathway.) Some kinases have dual-specificity kinase (EC 2.7.12
Protein_kinase
Mammalian protein found in Homo sapiens
cytoskeletal protein. In humans, it is a tumor suppressor protein involved in neurofibromatosis type II. Sequence data reveal its similarity to the ERM protein family
Merlin_(protein)
Mammalian protein found in humans
Cluster of differentiation 40, CD40 is a type I transmembrane protein found on antigen-presenting cells and is required for their activation. The binding
CD40
Mammalian protein
the RET gene results in the production of 3 different isoforms of the protein RET. RET51, RET43 and RET9 contain 51, 43 and 9 amino acids in their C-terminal
RET_proto-oncogene
Protein found in humans
was termed "nonsuppressible insulin-like activity" (NSILA). IGF1 is a protein that in humans is encoded by the IGF1 gene. IGF1 consists of 70 amino acids
Insulin-like_growth_factor_1
Protein and coding gene in humans
Interleukin 13 (IL-13) and its relative interleukin-4 are signalling proteins of the adaptive immune systems of vertebrates. They are immunoregulatory
Interleukin_13
Medical condition
encodes for the 770 amino acid protein, STAT3. STAT3 is part of a family of proteins known as the STAT protein. These proteins play an essential role in chemical
STAT3_GOF
Mammalian protein found in Homo sapiens
the complementary DNA and purification of the natural and recombinant proteins". Science. 228 (4701): 810–815. doi:10.1126/science.3923623. PMID 3923623
Granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage_colony-stimulating_factor
Cytokine, alarmin, and growth factor
leading to the activation of signal transducer and activator of transcription (STAT)5A and 5B and, to a lesser extent, STAT1 and 3. These transcription factors
Thymic_stromal_lymphopoietin
Protein-coding gene in the species Homo sapiens
length and includes 12 exons. The translated protein contains 629 amino acids; it is a type I penetrating protein and includes a signal peptide, an N-terminal
Interleukin-23_receptor
Protein-coding gene in the species Homo sapiens
known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene. The protein encoded by this gene is a proinflammatory cytokine
Interleukin_18
Mammalian protein found in humans
Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. The gene has been discovered in 1990 by in situ hybridisation
CCL5
Protein-coding gene in the species Homo sapiens
Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene. It has been shown to localize to the centrosome and has
PIBF1
Cytokine protein
acute phase response. IL-6 is responsible for stimulating acute phase protein synthesis, as well as the production of neutrophils in the bone marrow
Interleukin_6
Mammalian protein found in Homo sapiens
absence of cytokine, JAKs lack protein tyrosine kinase activity. Once activated, the JAKs create docking sites for the STAT transcription factors by phosphorylation
Janus_kinase_3
Protein-coding gene in humans
opposing receptor to recruit a STAT protein. JAK3 and JAK1 subsequently phosphorylate the recruited STAT, allowing the STAT to form a dimer or tetramer with
Common_gamma_chain
Mammalian protein found in humans
molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome17q23.3
CD31
Protein-coding gene in the species Homo sapiens
melanocytes IL6R gene expression may be regulated by MITF. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6
Interleukin-6_receptor
Protein and coding gene in humans
the Signal Transducer and Activator of Transcription (STAT) family of proteins. The proteins of STAT family transmit signals from a receptor complex to the
STAT6
Protein-coding gene in the species Homo sapiens
24 (IL-24) is a protein in the interleukin family, a type of cytokine signaling molecule in the immune system. In humans, this protein is encoded by the
Interleukin_24
Mammalian protein found in Mus musculus
IL-4 was isolated four years later confirming its similarity to a mouse protein called B cell stimulatory factor-1 (BCSF-1). IL-4 has been found to mediate
Interleukin_4
Protein-coding gene in humans
activator 1 is an enzyme that in humans is encoded by the CDK5R1 gene. The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent
CDK5R1
Mammalian protein found in Homo sapiens
sequence identity than LIFR and OSMR. Of the proteins recruited to type I cytokine receptors STAT proteins remain the best studied. Homodimerisation of
Oncostatin_M
Protein family
domain include the human pias family (protein inhibitor of activated STAT protein). The name MIZ is derived from Msx-interacting-zinc finger. The crystal
MIZ_zinc_finger
Family of intracellular tyrosine kinases
non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially named "just another kinase" 1 and 2 (since they
Janus_kinase
Hormone that regulates growth and development
simply as growth hormone (GH) somatotropin, is a protein that in humans is encoded by the GH1 gene. The protein encoded by this gene is a member of the somatotropin/prolactin
Growth_hormone_1
Mammalian protein found in humans
Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. Interleukin-21 is a cytokine that has potent regulatory effects on cells
Interleukin_21
Protein-coding gene in the species Homo sapiens
in that proteins encoded by these genes bind to a shared co-receptor complex. Formation of this complex leads to activation of the JAK-STAT signalling
Interferon_lambda_4
Mammalian protein and protein-coding gene
Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation 117) or mast/stem
KIT_(gene)
Buildup of metabolic waste due to kidney dysfunction
Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine. Protein toxicity has
Protein_toxicity
Protein-coding gene in the species Homo sapiens
lymphocyte maturation factor p40, or interleukin-12 subunit p40) is a protein subunit that in humans is encoded by the IL12B gene. IL-12B is a common
Interleukin-12_subunit_beta
Protein found in humans
(M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor
Colony stimulating factor 1 receptor
Colony_stimulating_factor_1_receptor
Protein-coding gene in the species Homo sapiens
kinases, a [phosphorylation] cascade will progress and is regulated by the STAT protein. Different responses result from the binding of each type I Interferon
IFNW1
American virologist
PMID: 1548771; PMCID: PMC289040. Horvath CM, Wen Z, Darnell JE, Jr. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding
Curt_M._Horvath
Gene involved in the most common form of dwarfism
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster
Fibroblast growth factor receptor 3
Fibroblast_growth_factor_receptor_3
Protein-coding gene in humans
Novel Neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a protein that in humans is encoded by the CLCF1 gene. CLCF1 is a cytokine. It induces
CLCF1
Medical condition
protein with excessive ALK activity. ALK is a tyrosine kinase that activities PI3K/AKT/mTOR, Ras-activated ERKs, Janus kinase-activated STAT proteins
Anaplastic large-cell lymphoma
Anaplastic_large-cell_lymphoma
Protein-coding gene in humans
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the PPP2CA gene. This gene encodes
PPP2CA
Protein-coding gene in the species Homo sapiens
Tyrosine-protein kinase 6 is an enzyme that in humans is encoded by the PTK6 gene. Tyrosine-protein kinase 6—also known as BRK (breast tumor kinase)—is
PTK6
Membrane receptor protein found in humans
(TNFα). The protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. This protein is one of
Tumor necrosis factor receptor 1
Tumor_necrosis_factor_receptor_1
Enzyme
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform is an enzyme that in humans is encoded by the PPP2R1A gene. In the plant
PPP2R1A
Protein family
refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are
STAT5
Protein-coding gene in the species Homo sapiens
activation. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family
STAT5A
Mammalian protein found in Homo sapiens
other proteins. The phosphorylation leads to association with JAK/Tyk tyrosine kinases and STAT protein transcription factors. In particular, STAT-3 is
Glycoprotein_130
Protein-coding gene in the species Homo sapiens
classes has yet to be elucidated. HDAC2 is broadly regulated by protein kinase 2 (CK2) and protein phosphatase 1 (PP1), but biochemical analysis suggests its
Histone_deacetylase_2
Protein-coding gene in the species Homo sapiens
cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known
SOCS2
Human protein linked to hemoglobin
by the HPX gene and belongs to the hemopexin family of proteins. Hemopexin is the plasma protein with the highest binding affinity for heme. Hemoglobin
Hemopexin
Protein involved in the binding of the growth hormone
Growth hormone receptor is a protein that in humans is encoded by the GHR gene. GHR orthologs have been identified in most mammals. Growth hormone receptor
Growth_hormone_receptor
Protein-coding gene in the species Homo sapiens
Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene. GRCh38: Ensembl release 89: ENSG00000120242 – Ensembl, May 2017 GRCm38: Ensembl
IFNA8
Protein found in humans
Zinc finger protein 226 is a protein that in humans is encoded by the ZNF226 gene. The zinc finger protein 226 is also known as the Kruppel-associated
Zinc_finger_protein_226
Type of signaling molecule
signal proteins of the signal transducer and activator of transcription (STAT) protein family – which include transcription factors for target genes that serve
Inflammatory_cytokine
Protein-coding gene in the species Homo sapiens
Inositol polyphosphate-5-phosphatase F is a protein that in humans is encoded by the INPP5F gene. The protein encoded by this gene is an inositol 1,4,5-trisphosphate
INPP5F
Protein-coding gene in the species Homo sapiens
Interleukin 3 (IL-3) is a protein that in humans is encoded by the IL3 gene localized on chromosome 5q31.1. Sometimes also called colony-stimulating factor
Interleukin_3
Protein-coding gene in the species Homo sapiens
factor ligand superfamily member 18 is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs
TNFSF18
Protein-coding gene in the species Homo sapiens
Signal-transducing adaptor protein 2 is a protein that in humans is encoded by the STAP2 gene. This gene encodes the substrate of breast tumor kinase,
STAP2
Heterodimeric receptor
is impacted by different STAT protein expression levels and activation of STAT heterodimers and STAT homodimers; reducing STAT expression levels alters
Interferon-alpha/beta receptor
Interferon-alpha/beta_receptor
Protein involved in blood vessel growth
Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. The chemical formula is C3914H6252N1212O1278S52
Vascular endothelial growth factor A
Vascular_endothelial_growth_factor_A
Class of cell surface receptors coupled to G-protein-associated intracellular signaling
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors
G_protein-coupled_receptor
Protein that binds to a cytokine
cells in diseases such as kidney disease or certain types of anemia. STAT protein Brooks, Andrew J.; Dehkhoda, Farhad; Kragelund, Birthe B. (2017). "Cytokine
Cytokine_receptor
Protein-coding gene in the species Homo sapiens
signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and production of antiviral proteins. Further consequences
Interleukin_29
Type I cytokine receptor and coding gene in humans
functions in the second messenger cascades, including: JAK-STAT pathway – the STAT protein family has been shown to have a key transduction role in cytokine
Prolactin_receptor
Protein-coding gene in the species Homo sapiens
SH2B adapter protein 3 (SH2B3), also known as lymphocyte adapter protein (LNK), is a protein that in humans is encoded by the SH2B3 gene on chromosome
SH2B3
Protein ranking for human nutrition
Protein quality is the digestibility and quantity of essential amino acids for providing the proteins in correct ratios for human consumption. There are
Protein_quality
Protein found in humans
Cyclin-dependent kinase 5 is a protein, and more specifically an enzyme, that is encoded by the Cdk5 gene. It was discovered 15 years ago,[when?] and
Cyclin-dependent_kinase_5
Protein-coding gene in the species Homo sapiens
PMID 9256341. S2CID 11835268. "Entrez Gene: PIAS2 protein inhibitor of activated STAT, 2". Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne
Protein inhibitor of activated STAT2
Protein_inhibitor_of_activated_STAT2
Protein-coding gene in the species Homo sapiens
phosphorylate receptor intracellular domains, leading to the activation of STAT protein family intracellular transcription factors STAT1 and STAT3. In addition
Interleukin_26
Protein-coding gene in the species Homo sapiens
Periodic tryptophan protein 1 homolog is a protein that in humans is encoded by the PWP1 gene. GRCm38: Ensembl release 89: ENSMUSG00000001785 – Ensembl
PWP1
Assembly of proteins inside biological cells
Protein biosynthesis, or protein synthesis, is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation
Protein_biosynthesis
Human chromosome
proteins: RNF43, RNF112, RNF135, RNF157, RNF167, RNF213, RNF222, RNF227 Schlafen family: SLFN5, SLFN11, SLFN12, SLFN12L, SLFN13, SLFN14 STAT proteins:
Chromosome_17
Family of genes
SOCS (suppressor of cytokine signaling proteins) refers to a family of genes involved in inhibiting the JAK-STAT signaling pathway. CISH SOCS1 SOCS2 SOCS3
Suppressor of cytokine signalling
Suppressor_of_cytokine_signalling
Protein-coding gene in the species Homo sapiens
Interferon alpha-4 is a protein that in humans is encoded by the IFNA4 gene. GRCh38: Ensembl release 89: ENSG00000236637 – Ensembl, May 2017 GRCm38: Ensembl
IFNA4
Protein that regulates the rate of DNA transcription
nuclear receptors). phosphorylation – Many transcription factors such as STAT proteins must be phosphorylated before they can bind DNA. interaction with other
Transcription_factor
Protein found in humans
Caveolin-1 is a protein that in humans is encoded by the CAV1 gene. The scaffolding protein encoded by this gene is the main component of the caveolae
Caveolin_1
Protein found in humans
McDonough sarcoma"), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene
CD135
Variant of somatotropin produced by placenta
placental growth hormone (PGH) or growth hormone variant (GH-V), is a protein that in humans is encoded by the GH2 gene. It is produced by and secreted
Growth_hormone_2
STAT PROTEIN
STAT PROTEIN
Boy/Male
English American
Stony field; lives by the stony grove.
Boy/Male
Bengali, Indian
Loop; Autumn
Boy/Male
Hindu
Praise
Boy/Male
Hindu, Indian, Marathi
Constant
Girl/Female
Indian
Moment, Time, Occasion, Truth, Essence, Worthy, Handsome, Strength honest, Existing, Real learned, A sage
Girl/Female
British, English
Star
Surname or Lastname
English
English : habitational name from any of the various minor places, for example Start Point in Devon, named from Old English steort ‘tail’, in the transferred sense of a promontory or spur of a hill.
Male
Swedish
Pet form of Swedish Gustaf, GÖSTA means "meditation staff."
Surname or Lastname
English and Welsh
English and Welsh : unexplained.
Girl/Female
Indian, Punjabi, Sikh
Praise
Girl/Female
American, Australian, British, Christian, English, Greek, Jamaican, Latin
Star; Esther; Stella; Inspiring
Male
Russian
(СтаÑ) Russian pet form of Slavic Stanislav, STAS means "glorious government."
Girl/Female
British, English, Jamaican
Star
Girl/Female
Muslim
Moment, Time, Occasion, Truth, Essence, Worthy, Handsome, Strength honest, Existing, Real learned, A sage
Male
English
Short form of English Stanley, STAN means "stone clearing," and other names containing Old English stan, meaning "stone."
Boy/Male
Slavic
Military glory.
Surname or Lastname
English
English : perhaps a variant of Sait, from the Old English personal name Sǣgēat (‘sea Geat’).
Girl/Female
Arabic, Muslim
Occasion; Moment; Time
Boy/Male
Anglo, Australian, British, English
Star
Girl/Female
English Latin
Star.
STAT PROTEIN
STAT PROTEIN
Boy/Male
Hindu, Indian, Telugu
Lord Krishna
Girl/Female
Gujarati, Hindu, Indian
Enjoyment; Full of Joy
Boy/Male
Shakespearean
Antony and Cleopatra'. Friend to Mark Antony.
Girl/Female
American, Australian, Chinese, Danish, German, Norse, Scandinavian, Swedish
Lime; Linden Tree
Girl/Female
Muslim
Proud
Surname or Lastname
English
English : occupational name for someone who made and drove in stakes, or a topographic name for someone who lived near a boundary post for example, from a derivative of Middle English stake ‘post’, ‘stake’.
Boy/Male
German Italian French
Power of an eagle.
Boy/Male
Tamil
Ragupathi | ரகà¯à®ªà®¤à¯€
God rathis husband
Girl/Female
American, Australian, British, Christian, Danish, Dutch, English, French, German, Greek, Hebrew
Dawn; Bright; Star
Girl/Female
Ukrainian American Teutonic Spanish
noble.
STAT PROTEIN
STAT PROTEIN
STAT PROTEIN
STAT PROTEIN
STAT PROTEIN
v. t.
Fig.: To injure secretly or by malicious falsehood or slander; as, to stab a person's reputation.
n.
A wound with a sharp-pointed weapon; as, to fall by the stab an assassin.
v. t.
To assign a seat to, or the seats of; to give a sitting to; as, to seat a church, or persons in a church.
n.
A castrated bull; -- called also bull stag, and bull seg. See the Note under Ox.
v. t.
To cause to move or act; to set going, running, or flowing; as, to start a railway train; to start a mill; to start a stream of water; to start a rumor; to start a business.
v. i.
To continue in a state.
v. t.
To put a seat or bottom in; as, to seat a chair.
v. i.
To fasten or secure with stays; as, to stay a flat sheet in a steam boiler.
a.
Belonging to the state, or body politic; public.
n.
The polestar; the north star.
n.
Fig.: An injury inflicted covertly or suddenly; as, a stab given to character.
n.
Rank; condition; quality; as, the state of honor.
v. t.
To place on a seat; to cause to sit down; as, to seat one's self.
v. i.
To be bright, or attract attention, as a star; to shine like a star; to be brilliant or prominent; to play a part as a theatrical star.
v. t.
To settle; to plant with inhabitants; as to seat a country.
v. i.
To be fixed or set; to stay.
n.
That part of a thing on which a person sits; as, the seat of a chair or saddle; the seat of a pair of pantaloons.
v. i.
To act as a "stag", or irregular dealer in stocks.
n.
A sitting; a right to sit; regular or appropriate place of sitting; as, a seat in a church; a seat for the season in the opera house.
n.
A part or surface on which another part or surface rests; as, a valve seat.