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Chemical compound
Toluidine blue, also known as TBO or tolonium chloride (INN) is a blue cationic (basic) dye used in histology (as the toluidine blue stain) and sometimes
Toluidine_blue
Property of chemical biologic staining
substances called chromotropes. For example, toluidine blue becomes dark blue (with a colour range from blue-red dependent on glycosaminoglycan content)
Metachromasia
Aryl amine
o-Toluidine (ortho-toluidine) is an organic compound with the chemical formula CH3C6H4NH2. It is the most important of the three isomeric toluidines. It
O-Toluidine
Chemical compound
(e.g. toluidine blue, methylene blue and azure A etc.), which are metachromatic due to switching from monomeric to stacked aggregates, Alcian blue is apparently
Alcian_blue_stain
Property of chemical dyeing or staining
chromatic (color). Toluidine blue is an example of a partially orthochromatic dye, as it stains nucleic acids by its orthochromatic color (blue), but stains
Orthochromasia
Technique used to enhance visual contrast of specimens observed under a microscope
complementing stains used alongside Bismark brown are Hematoxylin and Toluidine blue which provide better contrast within the histology sample. Carmine is
Staining
Immune cell found in connective tissue
been used with mast cells, including Toluidine blue, Giemsa, and combined Alcian Blue and Safranin O. Toluidine blue is one of the most common stains for
Mast_cell
Nervous system disease affecting nerves beyond the brain and spinal cord
Micrograph showing a vasculitic peripheral neuropathy; plastic embedded; Toluidine blue stain Specialty Neurology Symptoms Shooting pain, numbness, tingling
Peripheral_neuropathy
Lipid-containing residue associated with aging
Micrograph showing a cluster of lipofuscin particles (arrow) in a nerve cell of the brain; toluidine blue stain; scale bar = 10 microns (0.01 millimeters)
Lipofuscin
Babes. They appear reddish when stained with polychrome methylene blue or toluidine blue (metachromasia). Special staining techniques such as Albert's or
Volutin_granules
Lung inflammation due to fungal infection
organism in sputum or bronchoalveolar lavage (lung rinse). Staining with toluidine blue, silver stain, periodic acid-Schiff stain, or an immunofluorescence
Pneumocystis_pneumonia
Discontinued optical video disc format
methylene blue, prussian blue, brilliant cresyl blue, toluidine blue, Basic Blue 3, methylene green, Taylor's blue, Janus Green B, Meldola's blue, thionin
Flexplay
Histological staining method
that of nuclear staining by basic (cationic) dyes such as thionine or toluidine blue. Staining by basic dyes occurs only from solutions that are less acidic
H&E_stain
Study of disease of nervous system tissue
Micrograph of a vasculitic neuropathy. Plastic embedded. Toluidine blue stain.
Neuropathology
Surgery used to treat skin cancers
staining with hematoxylin and eosin (H&E) or other stains (Including Toluidine Blue) Interpretation of microscope slides (Pathology) Possible reconstruction
Mohs_surgery
White blood cell abnormality
Wright–Giemsa stain and, in mucopolysaccharidosis, stain metachromatically with toluidine blue. Metachromatic staining is not seen in Tay–Sachs disease. The granules
Alder–Reilly_anomaly
Type of connective tissue in animals
elastic stain in histological sections. The permanganate-bisulfite-toluidine blue reaction is a highly selective and sensitive method for demonstrating
Elastic_fiber
Mucus-producing cells in stomach lining protective against gastric acid
correctly the cells stain strongly with special techniques like PAS or toluidine blue, the last representing the anionic nature of foveolar cell secretions
Foveolar_cell
yellow Clayton yellow Direct yellow 9 19540 azo 1829-00-1 Toluidine blue Tolonium chloride Basic blue 17 52040 thiazin 92-31-9 Tropaeolin O Chrysoine resorcinol
List_of_dyes
Photochemical antimicrobial technology
of morbidity and mortality. Photosensitizers such as methylene blue and toluidine blue have been incorporated into silicone, the main polymer used in
Antimicrobial photodynamic therapy
Antimicrobial_photodynamic_therapy
Kidney disease
C3 trapping in areas of collapse/sclerosis. (F) Semi-fine stained in Toluidine Blue (63×) with collapse of the entire glomerular tuft and hyperplasia of
Focal segmental glomerulosclerosis
Focal_segmental_glomerulosclerosis
American drug technician, identifier of first known AIDS cluster
Pneumocystis jirovecii cysts from bronchoalveolar lavage, stained with Toluidine blue O stain
Sandy_Ford
Gastrointestinal endoscopic imaging with dyes
with methylene blue staining. Also, methylene blue has been used to identify dysplasia in patients with ulcerative colitis. Toluidine blue stains nuclei
Chromoendoscopy
Precancerous white or grey lesion within the mouth
from areas of dysplasia or carcinoma under blue light or by initially staining of the mucosa with toluidine blue or dilute acetic acid and examination under
Leukoplakia
Cancer of the lining of the lips, mouth, or upper throat
may also reduce diagnostic costs. Other screening methods, including toluidine blue staining and fluorescence imaging, have not shown enough evidence for
Oral_cancer
Blue-colored dye
exclusion method. Trypan blue is derived from toluidine, that is, any of several isomeric bases, C14H16N2, derived from toluene. Trypan blue is so-called because
Trypan_blue
Genus of bacteria
Longitudinal section of a Frankia nodule dyed with toluidine blue to highlight the vascular tissue in blue and purple.
Frankia
Medical condition
Blasts & immature/mature basophils with metachromasia on toluidine blue staining Blasts are negative for cytochemical MPO, SBB, and NSE No expression of
Acute_basophilic_leukemia
Specialized anatomy and physiology of bacteria
metachromatic effect; they appear red or blue when stained with the blue dyes methylene blue or toluidine blue. Gas vacuoles are membrane-bound, spindle-shaped
Bacterial_cell_structure
Imaging and diffraction using electrons that pass through samples
cut from the block face. The thick sections are crudely stained with toluidine blue and examined for specimen and block orientation before thin sectioning
Transmission electron microscopy
Transmission_electron_microscopy
Human disease
a considerable number of mast cells. Special stains, such Giemsa or toluidine blue, are highly helpful in the diagnostic evaluation because they aid to
Telangiectasia macularis eruptiva perstans
Telangiectasia_macularis_eruptiva_perstans
Interstitial cells
on toluidine blue stained semithin section (~1 μm thick ultramicrotome) Figure 14. Electron micrographs illustrates the relationships of TC (blue) with
Telocyte
Blood in the feces that is not visibly apparent
normal tissue, by either marking the abnormally increased DNA content (toluidine blue) or failing to stain the tumor, possibly due to decreased surface glycogen
Fecal_occult_blood
biosensors utilizing the small molecule cationic dye toluidine blue to detect miRNA-21. Toluidine blue acts as a miRNA intercalative label through electrostatic
MicroRNA_biosensors
Protein-coding gene in the species Homo sapiens
basophils: a comparative analysis using multi-color flow cytometry and toluidine blue/immunofluorescence staining techniques". Tissue Antigens. 54 (5): 499–507
P-selectin glycoprotein ligand-1
P-selectin_glycoprotein_ligand-1
Dye
acid and dermatan sulfate on agarose-gel by sequential staining with toluidine blue and Stains-All". Journal of Chromatography. B, Analytical Technologies
Stains-all
Topics referred to by the same term
Force (Tenaga Bantuan Operasi) of Indonesian National Armed Forces Toluidine blue O, a purple-staining chemical used clinically and for histology TBO
TBO
Rapid staining method for detection of malaria
Mrinalini, VazhayilRamunny (2013). "Rapid detection of malaria parasite by toluidine blue method: A new staining method". Journal of Global Infectious Diseases
Jaswant Singh–Bhattacharji stain
Jaswant_Singh–Bhattacharji_stain
Medical condition
Screening investigations may include adjunctive diagnostic tools such as toluidine blue staining, autofluorescence imaging, and brush cytology, which can be
Oral and maxillofacial pathology
Oral_and_maxillofacial_pathology
Canadian psychologist, microbiologis,t and plant biologist
McCully, M.E. (1964). "Polychromatic staining of plant cell walls by toluidine blue O" (PDF). Protoplasma. 59 (2): 368–373. doi:10.1007/BF01248568. S2CID 33072349
Margaret_E._McCully
using a light microscope by viewing semithin sections stained with toluidine blue. The block is then retrimmed and the specific area for observation is
Diagnostic electron microscopy
Diagnostic_electron_microscopy
Single-species lichen genus
the ascospores are colourless (hyaline). A standard laboratory stain (toluidine blue) does not produce the red-violet reaction seen in some superficially
Frigidopyrenia
DNA integrity using two cytochemical tests: Acridine orange test and toluidine blue assay". Andrologia. 49 (10) e12765. doi:10.1111/and.12765. PMID 28224638
Sperm Chromatin Structure Assay
Sperm_Chromatin_Structure_Assay
Chemical compound
conjunction with toluidine blue to help visualize H. pylori. The resulting structures are stained as follows: – Mucin: yellow – H. pylori: blue – Other cellular
Alcian_yellow
Protein-coding gene in the species Homo sapiens
basophils: a comparative analysis using multi-color flow cytometry and toluidine blue/immunofluorescence staining techniques". Tissue Antigens. 54 (5): 499–507
BST1
neurothekeoma) Extraskeletal chondroma Thioflavin T Amyloidosis Colloid milium Toluidine blue Mast cell Mastocytosis Mucopolysaccharidoses Papular mucinosis Scleredema
List of histologic stains that aid in diagnosis of cutaneous conditions
List_of_histologic_stains_that_aid_in_diagnosis_of_cutaneous_conditions
Type of skin cancer
showed that the majority of tumour cells were positive for PAS diastase, toluidine blue, cytokeratins (CAM5.2, CK7), S-100 protein and GCDFP-15." Although some
Malignant_chondroid_syringoma
Species of marine parasite
help of some stainings, such as periodic acid-Schiff (PAS), Giemsa or toluidine blue, or some lectins. However, when the parasite is in low numbers or with
Enteromyxum_leei
Chemical compound
(Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 669. doi:10.1039/9781849733069-00648. ISBN 978-0-85404-182-4. The names 'toluidine',
P-Anisidine
Application of fine-needle aspiration
For immediate interpretation, fixed slides are stained with undiluted toluidine blue and read with brightfield microscopy after 15 seconds. Patients take
FNA_mapping
Chemist
A. M.; Greer, A.; Fuentealba, D. (2021). "Fatty acid conjugates of toluidine blue O as amphiphilic photosensitizers: synthesis, solubility, photophysics
Angel_A._Martí
Local anesthetic of the amino amide type
some patients, ortho-toluidine, a metabolite of prilocaine, may cause methemoglobinemia, which may be treated with methylene blue. Prilocaine may also
Prilocaine
Class of autoantibodies found in mammals
potent antithrombin activity whose action could be inhibited by toluidine blue or methylene blue". Am. J. Hematol. 24 (2): 207–14. doi:10.1002/ajh.2830240212
Anti-thrombin_antibodies
Chemical compound
(Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 669. doi:10.1039/9781849733069-00648. ISBN 978-0-85404-182-4. The names 'toluidine',
M-Anisidine
Chemical compound
(Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 669. doi:10.1039/9781849733069-00648. ISBN 978-0-85404-182-4. The names 'toluidine',
O-Anisidine
Chemical compound
showed that toluidine must be present to make these dyes. Aniline dyes, including mauve, are prepared from aniline-containing amounts of toluidine. One can
History of synthetic colourants
History_of_synthetic_colourants
Classification of agents that are possibly carcinogenic to humans
(o-Tolidine) 1,1-Dimethylhydrazine Dimethyl hydrogen phosphite Dimethyl-p-toluidine 3,7-Dinitrofluoranthene 3,9-Dinitrofluoranthene 1,3-Dinitropyrene 1,6-Dinitropyrene
IARC_group_2B
Chemical compound
2-Tolidine (orthotolidine, o-tolidine; not to be confused with o-toluidine) is an organic compound with the chemical formula (C6H4(CH3)NH2)2. Several
Tolidine
Chloronitrobenzenes Chloropropham Chloroquine 5-Chloro-ortho-toluidine 2-Chloro-1,1,1-trifluoroethane Cholesterol Chromium(III) compounds Chromium
IARC_group_3
German chemist (1818–1892)
constitution of styrole. A subsequent paper, Muspratt and Hofmann's "On Toluidine", described some of the first "synthetical experiments" (synthetische
August_Wilhelm_von_Hofmann
Liquid additive
impurities in the product that are formed from the toluidine isomers (ortho-, meta-, and para-toluidine) and meta-diamino toluene which are side-products
Antifreeze
Heterocyclic aromatic organic compound
suffix idine was added in compliance with the chemical nomenclature, as in toluidine, to indicate a cyclic compound containing a nitrogen atom. The chemical
Pyridine
Organic compound (C6H5NH2); simplest aromatic amine
are known where the phenyl group is further substituted. These include toluidines, xylidines, chloroanilines, aminobenzoic acids, nitroanilines, and many
Aniline
Medical condition
include primaquine and tafenoquine. Dapsone, methylene blue, pegloticase, rasburicase, and toluidine should also be avoided by people with G6PD deficiency
Glucose-6-phosphate dehydrogenase deficiency
Glucose-6-phosphate_dehydrogenase_deficiency
Chemicals regulated in the United States
Chlorothalonil 1897-45-6 p-Chloro-o-toluidine 95-69-2 Strong acid salts of p-Chloro-o-toluidine – 5-Chloro-o-toluidine and its strong acid salts 95-79-4
California Proposition 65 list of chemicals
California_Proposition_65_list_of_chemicals
Chemical compound
bisulfite-reduction of HMF. Winkler photometric method is a colour-reaction using p-toluidine and barbituric acid (DIN 10751–1). Photometric test may be unspecific
Hydroxymethylfurfural
Urinary system cancer that begins in the urinary bladder
certain aromatic amines, namely benzidine, beta-naphthylamine, and ortho-toluidine used in the metalworking and dye industries, can increase the risk of
Bladder_cancer
Concentration of glucose present in the blood (Glycaemia)
other reducing substances interfere with reaction. B. Condensation Ortho-toluidine method Uses aromatic amines and hot acetic acid. Forms glycosylamine and
Blood_sugar_level
Antidepressant
reversible inhibitor of MAO-A (RIMA). The reaction between glycidol (1) and m-toluidine (2) gives 3-m-toluidinopropane-1,2-diol (3). Treatment with diethyl carbonate
Toloxatone
Medical condition
exposed to vinyl chloride, carbon disulfide, rotating shift work, and o-toluidine at a chemical manufacturing plant". American Journal of Industrial Medicine
Occupational cardiovascular disease
Occupational_cardiovascular_disease
one attempt, Perkin oxidized aniline using potassium dichromate, whose toluidine impurities reacted with the aniline and yielded a black solid—suggesting
History_of_chemistry
Chemical company in Bydgoszcz, Poland
launched in Bydgoszcz, manufacturing, among others, aniline, nitrobenzene, toluidine, hydrazine, colorants, polyvinite or phenol. Local brine from mines in
Zachem Chemical Plant in Bydgoszcz
Zachem_Chemical_Plant_in_Bydgoszcz
MeSH D02.092.146.755 – rosaniline dyes MeSH D02.092.146.859 – toluidines MeSH D02.092.146.859.717 – trifluralin MeSH D02.092.200.650 – pargyline
List_of_MeSH_codes_(D02)
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TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
TOLUIDINE BLUE
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