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BITOPERTIN

  • Bitopertin

    • Chemical compound

    Bitopertin (developmental code names RG1678; RO-4917838) is a glycine reuptake inhibitor which was under development by Roche as an adjunct to antipsychotics

    Bitopertin

    Bitopertin

    Bitopertin

  • Pentobarbital

    • Short-acting barbiturate

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pentobarbital

    Pentobarbital

    Pentobarbital

  • Alcohol (drug)

    • Active ingredient in fermented drinks

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Alcohol (drug)

    Alcohol (drug)

    Alcohol_(drug)

  • Clonazepam

    • Benzodiazepine medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Clonazepam

    Clonazepam

    Clonazepam

  • Propofol

    • Intravenous medication used in anesthesia

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Propofol

    Propofol

    Propofol

  • Sodium thiopental

    • Barbiturate general anesthetic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Sodium thiopental

    Sodium thiopental

    Sodium_thiopental

  • Diazepam

    • Benzodiazepine sedative

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Diazepam

    Diazepam

    Diazepam

  • Barbiturate

    • Class of depressant drugs derived from barbituric acid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Barbiturate

    Barbiturate

    Barbiturate

  • Nitrous oxide

    • Colourless non-flammable greenhouse gas

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Nitrous oxide

    Nitrous oxide

    Nitrous_oxide

  • Chloroform

    • CHCl3, historical anaesthetic and common solvent

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Chloroform

    Chloroform

  • Mesylate

    • Salt or ester of methanesulfonic acid (CH3–SO2–OH)

    sotalol, ibutilide, sematilide, dronedarone, dofetilide, E-4031, and bitopertin.[citation needed] Mesylate salts are often used in preparing the dosage

    Mesylate

    Mesylate

    Mesylate

  • Taurine

    • Aminosulfonic acid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Taurine

    Taurine

    Taurine

  • SNG-12

    • Experimental psychiatric drug

    molecule, but its chemical structure does not appear to have been disclosed. Bitopertin Iclepertin Tilapertin "SNG 12". AdisInsight. 23 September 2022. Retrieved

    SNG-12

    SNG-12

  • Xenon

    • Chemical element with atomic number 54 (Xe)

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Xenon

    Xenon

    Xenon

  • Caffeine

    • Central nervous system stimulant

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Caffeine

    Caffeine

    Caffeine

  • Iclepertin

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Iclepertin

    Iclepertin

    Iclepertin

  • Diethyl ether

    • Organic chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Diethyl ether

    Diethyl ether

    Diethyl_ether

  • Glycine reuptake inhibitor

    • or more of the glycine transporters (GlyTs). Examples of GRIs include bitopertin (RG1678), iclepertin (BI-425809), ORG-24598, ORG-25935, ALX-5407, and

    Glycine reuptake inhibitor

    Glycine_reuptake_inhibitor

  • Toluene

    • Aromatic hydrocarbon

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Toluene

    Toluene

    Toluene

  • Chloral hydrate

    • Chemical sedative and hypnotic drug

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Chloral hydrate

    Chloral hydrate

    Chloral_hydrate

  • Flunitrazepam

    • Benzodiazepine sedative

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Flunitrazepam

    Flunitrazepam

    Flunitrazepam

  • Strychnine

    • Poisonous substance used as pesticide

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Strychnine

    Strychnine

    Strychnine

  • Glycinergic

    • Class of chemical compounds

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Glycinergic

    Glycinergic

  • Threonine

    • Amino acid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Threonine

    Threonine

    Threonine

  • Etomidate

    • Short-acting anaesthetic and sedative drug

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Etomidate

    Etomidate

    Etomidate

  • Ivermectin

    • Medication for parasite infestations

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Ivermectin

    Ivermectin

    Ivermectin

  • Pethidine

    • Opioid analgesic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pethidine

    Pethidine

    Pethidine

  • Furosemide

    • Loop diuretic medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Furosemide

    Furosemide

    Furosemide

  • Colchicine

    • Medication mainly used to treat gout

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Colchicine

    Colchicine

    Colchicine

  • Morphine

    • Pain medication of the opiate family

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Morphine

    Morphine

    Morphine

  • Benzylpenicillin

    • Antibiotic medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Benzylpenicillin

    Benzylpenicillin

    Benzylpenicillin

  • Alanine

    • Α-amino acid that is used in the biosynthesis of proteins

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Alanine

    Alanine

    Alanine

  • Proline

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Proline

    Proline

    Proline

  • Clomethiazole

    • Sedative/Hypnotic medication for alcohol withdrawal

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Clomethiazole

    Clomethiazole

    Clomethiazole

  • Verapamil

    • Calcium channel blocker medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Verapamil

    Verapamil

    Verapamil

  • Tetrahydrocannabinol

    • Psychoactive component of cannabis

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Tetrahydrocannabinol

    Tetrahydrocannabinol

    Tetrahydrocannabinol

  • Codeine

    • Opiate and prodrug of morphine used to treat pain

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Codeine

    Codeine

    Codeine

  • Bromazepam

    • Benzodiazepine drug

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Bromazepam

    Bromazepam

    Bromazepam

  • Nifedipine

    • Calcium channel blocker medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Nifedipine

    Nifedipine

    Nifedipine

  • Erythropoietic protoporphyria

    • Medical condition

    analysis of carotene treatment has called its effectiveness into question. Bitopertin has been undergoing trials in Australia since 2022 with some success in

    Erythropoietic protoporphyria

    Erythropoietic protoporphyria

    Erythropoietic_protoporphyria

  • Flurazepam

    • Hypnotic medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Flurazepam

    Flurazepam

    Flurazepam

  • Thebaine

    • Opiate alkaloid constituent of opium

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Thebaine

    Thebaine

    Thebaine

  • Allopregnanolone

    • Endogenous inhibitory neurosteroid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Allopregnanolone

    Allopregnanolone

    Allopregnanolone

  • Isobutyric acid

    • Carboxylic acid with chemical formula (CH3)2CHCO2H

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Isobutyric acid

    Isobutyric acid

    Isobutyric_acid

  • List of investigational obsessive–compulsive disorder drugs

    • Investigational obsessive–compulsive disorder drugs

    atypical antipsychotic (non-selective monoamine receptor modulator [13] Bitopertin (DISC-1459; R-1678; RG-6178; RG1678; RO-4917838) – glycine transporter

    List of investigational obsessive–compulsive disorder drugs

    List_of_investigational_obsessive–compulsive_disorder_drugs

  • Tert-Butyl alcohol

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Tert-Butyl alcohol

    Tert-Butyl alcohol

    Tert-Butyl_alcohol

  • Methoxyflurane

    • Volatile anaesthesia medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Methoxyflurane

    Methoxyflurane

    Methoxyflurane

  • Sevoflurane

    • Inhalational anaesthetic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Sevoflurane

    Sevoflurane

    Sevoflurane

  • Pesampator

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pesampator

    Pesampator

    Pesampator

  • Serine

    • Amino acid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Serine

    Serine

    Serine

  • Halothane

    • General anaesthetic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Halothane

    Halothane

    Halothane

  • Glycine

    • Amino acid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Glycine

    Glycine

    Glycine

  • Isoflurane

    • Inhalational anesthetic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Isoflurane

    Isoflurane

    Isoflurane

  • Tropisetron

    • Serotonin antagonist/antiemetic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Tropisetron

    Tropisetron

    Tropisetron

  • Trichloroethylene

    • C2HCl3, widely used industrial solvent

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Trichloroethylene

    Trichloroethylene

    Trichloroethylene

  • Anandamide

    • Chemical compound (fatty acid neurotransmitter)

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Anandamide

    Anandamide

    Anandamide

  • Dehydroepiandrosterone sulfate

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Dehydroepiandrosterone sulfate

    Dehydroepiandrosterone sulfate

    Dehydroepiandrosterone_sulfate

  • Alkylbenzene sulfonate

    • Class of chemical compounds

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Alkylbenzene sulfonate

    Alkylbenzene sulfonate

    Alkylbenzene_sulfonate

  • Hypotaurine

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Hypotaurine

    Hypotaurine

    Hypotaurine

  • Picrotoxin

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Picrotoxin

    Picrotoxin

    Picrotoxin

  • Isoflurothyl

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Isoflurothyl

    Isoflurothyl

    Isoflurothyl

  • Alfaxalone

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Alfaxalone

    Alfaxalone

    Alfaxalone

  • Β-Alanine

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Β-Alanine

    Β-Alanine

    Β-Alanine

  • Desflurane

    • Inhalational anesthesia medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Desflurane

    Desflurane

    Desflurane

  • ASP2535

    • Type 1 Glycine transporter inhibitor

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    ASP2535

    ASP2535

    ASP2535

  • Levorphanol

    • Opioid analgesic drug

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Levorphanol

    Levorphanol

    Levorphanol

  • 2-Arachidonoylglycerol

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    2-Arachidonoylglycerol

    2-Arachidonoylglycerol

    2-Arachidonoylglycerol

  • Bilobalide

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Bilobalide

    Bilobalide

    Bilobalide

  • 1,1,1-Trichloroethane

    • Solvent, now banned for ozone depletion

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    1,1,1-Trichloroethane

    1,1,1-Trichloroethane

    1,1,1-Trichloroethane

  • 3-Phosphoglyceric acid

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    3-Phosphoglyceric acid

    3-Phosphoglyceric acid

    3-Phosphoglyceric_acid

  • 2,2,2-Trifluoroethanol

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    2,2,2-Trifluoroethanol

    2,2,2-Trifluoroethanol

    2,2,2-Trifluoroethanol

  • Pharmacology of ethanol

    • Pharmacodynamics and pharmacokinetics of ethanol

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pharmacology of ethanol

    Pharmacology of ethanol

    Pharmacology_of_ethanol

  • Pregnenolone (medication)

    • Medication and supplement

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pregnenolone (medication)

    Pregnenolone (medication)

    Pregnenolone_(medication)

  • Chlorobutanol

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Chlorobutanol

    Chlorobutanol

  • Pregnenolone

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pregnenolone

    Pregnenolone

    Pregnenolone

  • Riluzole

    • Medication used to treat amyotrophic lateral sclerosis

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Riluzole

    Riluzole

    Riluzole

  • Ginkgolide

    • Biologically active terpenic lactone

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Ginkgolide

    Ginkgolide

    Ginkgolide

  • Sarcosine

    • Amino acid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Sarcosine

    Sarcosine

    Sarcosine

  • Nicardipine

    • Antihypertensive drug of the calcium channel blocker class

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Nicardipine

    Nicardipine

    Nicardipine

  • Brucine

    • Poisonous alkaloid similar to strychnine

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Brucine

    Brucine

    Brucine

  • Glycine receptor

    • Widely distributed inhibitory receptor in the central nervous system

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Glycine receptor

    Glycine receptor

    Glycine_receptor

  • THAZ

    • Pharmaceutical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    THAZ

    THAZ

    THAZ

  • Gelsemine

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Gelsemine

    Gelsemine

    Gelsemine

  • Corymine

    • Chemical compound, neurotoxin

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Corymine

    Corymine

    Corymine

  • Glycine transporter

    • Protein family

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Glycine transporter

    Glycine_transporter

  • Amoxapine

    • Tricyclic antidepressant medication

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Amoxapine

    Amoxapine

    Amoxapine

  • Nifoxipam

    • Benzodiazepine designer drug

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Nifoxipam

    Nifoxipam

    Nifoxipam

  • Levomethorphan

    • Opioid analgesic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Levomethorphan

    Levomethorphan

    Levomethorphan

  • Glycine receptor agonist

    • chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Glycine receptor agonist

    Glycine_receptor_agonist

  • Pregnanolone

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Pregnanolone

    Pregnanolone

    Pregnanolone

  • Daidzein

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Daidzein

    Daidzein

    Daidzein

  • Genistein

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Genistein

    Genistein

    Genistein

  • Levomethadone

    • Synthetic opioid

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Levomethadone

    Levomethadone

    Levomethadone

  • ORG-24598

    • Selective inhibitor of Glycine transporter 1

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    ORG-24598

    ORG-24598

    ORG-24598

  • Picolinic acid

    • Pyridine-2-carboxylic acid; bidentate chelating agent

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Picolinic acid

    Picolinic acid

    Picolinic_acid

  • Enflurane

    • Obsolete anaesthetic

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Enflurane

    Enflurane

    Enflurane

  • Tribromoethanol

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Tribromoethanol

    Tribromoethanol

    Tribromoethanol

  • Nipecotic acid

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Nipecotic acid

    Nipecotic acid

    Nipecotic_acid

  • Bicuculline

    • Chemical compound

    chloride-dependent glycine transporter 1 ACPPB ALX-5407 (NFPS) ASP2535 Bitopertin (RG1678/RO4917838) CP-802079 Ethanol (alcohol) Glycyldodecylamide GSK1018921

    Bicuculline

    Bicuculline

    Bicuculline

  • List of investigational antipsychotics

    • Investigational antipsychotics

    partial agonist and serotonin 5-HT1A receptor agonist – schizophrenia [151] Bitopertin (DISC-1459; R-1678; RG-6718; RG-6178; RG1678; RO-4917838; RO4917838) –

    List of investigational antipsychotics

    List_of_investigational_antipsychotics

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