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Amino acid
Sarcosine, also known as N-methylglycine, or monomethylglycine, is a non-proteinogenic amino acid with the formula CH3N(H)CH2CO2H. It is the N-methyl
Sarcosine
Class of enzymes
enzymology, sarcosine dehydrogenase (EC 1.5.8.3) is a mitochondrial enzyme that catalyzes the chemical reaction N-demethylation of sarcosine to give glycine
Sarcosine_dehydrogenase
Sarcosine oxidase is an enzyme (EC 1.5.3.1) that catalyzes the oxidative demethylation of sarcosine to yield glycine. sarcosine + H2O O2 H2O2
Sarcosine_oxidase
In enzymology, a sarcosine reductase (EC 1.21.4.3) is an enzyme that catalyzes the chemical reaction acetyl phosphate + methylamine + thioredoxin disulfide
Sarcosine_reductase
Glycine/sarcosine N-methyltransferase (EC 2.1.1.156, ApGSMT, glycine-sarcosine methyltransferase, GSMT, GMT, glycine sarcosine N-methyltransferase,
Glycine/sarcosine N-methyltransferase
Glycine/sarcosine_N-methyltransferase
Sarcosine/dimethylglycine N-methyltransferase (EC 2.1.1.157, ApDMT, sarcosine-dimethylglycine methyltransferase, SDMT, sarcosine dimethylglycine N-methyltransferase
Sarcosine/dimethylglycine N-methyltransferase
Sarcosine/dimethylglycine_N-methyltransferase
Chemical compound
MagneINNO. Retrieved 12 August 2026. Clulow R, Lightfoot P (2018). "New sarcosine–metal halide complexes related to ferroelectric TSCC". CrystEngComm. 20
Magnesium_glycinate
dimethylglycine + electron-transferring flavoprotein H2O H2O sarcosine + H2C=O + reduced flavoprotein The three substrates of this enzyme
Dimethylglycine_dehydrogenase
Glycine/sarcosine/dimethylglycine N-methyltransferase (EC 2.1.1.162, GSDMT, glycine sarcosine dimethylglycine N-methyltransferase) is an enzyme with systematic
Glycine/sarcosine/dimethylglycine N-methyltransferase
Glycine/sarcosine/dimethylglycine_N-methyltransferase
Short-acting barbiturate
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Pentobarbital
Class of enzymes
Specifically, this enzyme breaks the amidino C-N bond in creatine, producing sarcosine and urea. Creatinase activity has been described in several bacteria species
Creatinase
Class of enzymes
sarcosine + SAH The enzyme catalyses a methylation reaction in which the amino acid glycine is converted to sarcosine. The methyl group
Glycine_N-methyltransferase
Medical condition
increased concentration of sarcosine in blood plasma and urine ("sarcosinuria"). It can result from an inborn error of sarcosine metabolism, or from severe
Sarcosinemia
Surfactant
(INCI), also known as sarcosyl, is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste
Sodium_lauroyl_sarcosinate
Index of chemical compounds with the same molecular formula
Propyl nitrite Lactamide Nitropropanes 1-Nitropropane 2-Nitropropane Sarcosine This set index page lists chemical structure articles associated with
C3H7NO2
Chemical compound
Peptide bonds to proline, and to other N-substituted amino acids (such as sarcosine), are able to populate both the cis and trans isomers. Most peptide bonds
Proline
Aminosulfonic acid
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Taurine
Benzodiazepine medication
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Clonazepam
Chemical compound
to indigo dye. It is a non-proteinogenic alpha amino acid related to sarcosine, but with an N-phenyl group in place of N-methyl. It is prepared by the
N-Phenylglycine
Widely distributed inhibitory receptor in the central nervous system
Hypotaurine Ivermectin L-Alanine L-Proline L-Serine Milacemide Quisqualamine Sarcosine Taurine THC L-Theanine Ethanol Toluene Zonisamide Bicuculline Brucine
Glycine_receptor
Benzodiazepine sedative
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Diazepam
Amino acids containing a secondary amine
N-substituted amino acids. In nature, proline, hydroxyproline, pipecolic acid and sarcosine are well-known secondary amino acids. Proline is the only proteinogenic
Secondary_amino_acid
Intravenous medication used in anesthesia
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Propofol
Medication of the barbiturate type
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Phenobarbital
Type of protein secondary structure
bonds that replace proline with another N-substituted amino acid (such as sarcosine) are also likely to adopt the cis isomer. The PPII helix is defined by
Polyproline_helix
Chemical compound
(MAE), diethanolamine (DEA), amino acids bicine, glycine and hydroxyethyl sarcosine (HES), formyl amides of MAE and DEA, ammonia, and stable salts formate
Methyldiethanolamine
Barbiturate general anesthetic
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Sodium_thiopental
Chemical compound
N-Oleoylsarcosine (Sarkosyl O) is an amphiphilic oleic acid derivative having a sarcosine head group (N-methylglycine) which is used as a water-in-oil emulsifier
N-Oleoylsarcosine
Salt or ester of formic acid
systems. It is formed from many precursors including choline, serine, and sarcosine. It provides a C-1 source in the biosynthesis of some nucleic acids. Formate
Formate
Protein-coding gene in the species Homo sapiens
Sarcosine dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the SARDH gene. GRCh38: Ensembl release 89: ENSG00000123453 – Ensembl
SARDH
Spice made from crocus flowers
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Saffron
Class of depressant drugs derived from barbituric acid
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Barbiturate
Experimental psychiatric drug
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
SNG-12
Chemical compound, neurotoxin
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Corymine
Amino acid
ALS symptoms has yet to be shown. A 2011 meta-analysis found adjunctive sarcosine to have a medium effect size for negative and total symptoms of schizophrenia
Serine
sarcocele, sarcoid, sarcoidosis, sarcoma, sarcophagus, Sarcopterygii, sarcosine, sarcosinemia, sarcosome sarc- tailor Latin sartor "tailor", from sarcire
List of Greek and Latin roots in English/P–Z
List_of_Greek_and_Latin_roots_in_English/P–Z
Dissociative anesthetic and anti-depressant
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Ketamine
Chemical element with atomic number 12 (Mg)
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Magnesium
Dissociative hallucinogenic drug, mostly used recreationally
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Phencyclidine
Organic chemical compound
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Diethyl_ether
Chemical compound
ingredients. A guanidino group is introduced by reaction of cyanamide with sarcosine In the industrial synthesis of creatine:. This synthesis route mostly
Cyanamide
Example of the well-known 1,3-dipolar cycloaddition of azomethine ylides to olefins
to the functionalization of fullerenes and nanotubes. The amino acid sarcosine reacts with paraformaldehyde when heated at reflux in toluene to an ylide
Prato_reaction
It involves both oxidation and reduction in process
Clostridioides difficile, C. sporogenes, and C. botulinum. Additionally, sarcosine and betaine can act as electron acceptors. Nisman, B. (1954). "The Stickland
Stickland_fermentation
O2 H2O2 sarcosine + H2C=O The three substrates of this enzyme are dimethylglycine, water and oxygen. Its products are sarcosine, hydrogen peroxide
Dimethylglycine_oxidase
Benzodiazepine sedative
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Flunitrazepam
Glutamate receptor and ion channel protein found in nerve cells
agonist Milacemide – synthetic glycine site agonist; prodrug of glycine Sarcosine (monomethylglycine) – endogenous glycine site agonist Serine (D-serine
NMDA_receptor
Diuretic medication
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Hydrochlorothiazide
Α-amino acid that is used in the biosynthesis of proteins
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Alanine
Carboxylic acid with chemical formula (CH3)2CHCO2H
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Isobutyric_acid
Class of enzymes
acid (N-carbamoylsarcosine) to sarcosine, carbon dioxide, and ammonia: 3-methylhydantoic acid H2O NH3 sarcosine + CO2 The reaction is part of
N-carbamoylsarcosine_amidase
Amino acid
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Aspartic_acid
Chemical compound
analogous to the synthesis of creatine starting from 2-methylaminoethanol via sarcosine. This synthetic route suppresses the formation of toxic dihydrotriazine
Glycocyamine
Large biological molecule that acts as a catalyst
amino-terminal methionine in new proteins while creatinase hydrolyses creatine to sarcosine and urea). In addition, MAP is metal-ion dependent while creatinase is
Enzyme
Medication mainly used to treat gout
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Colchicine
CHCl3, historical anaesthetic and common solvent
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Chloroform
Opioid analgesic
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Pethidine
Class of drugs
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
AMPA receptor positive allosteric modulator
AMPA_receptor_positive_allosteric_modulator
Class of anesthetics
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
NMDA_receptor_antagonist
Topics referred to by the same term
railway station, in England GMT (TV programme), United Kingdom Glycine/sarcosine N-methyltransferase, an enzyme G:MT – Greenwich Mean Time, a 1999 British
GMT_(disambiguation)
Amino acids not naturally encoded in the genome
than of vitamins (cofactor auxotrophy). [citation needed] The osmolytes, sarcosine and glycine betaine are derived from amino acids, but have a secondary
Non-proteinogenic_amino_acids
Psychoactive component of cannabis
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Tetrahydrocannabinol
Type 1 Glycine transporter inhibitor
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
ASP2535
Typical antipsychotic medication
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Haloperidol
Pyridine-2-carboxylic acid; bidentate chelating agent
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Picolinic_acid
Active ingredient in fermented drinks
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Alcohol_(drug)
Poisonous alkaloid similar to strychnine
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Brucine
Molecule able to contain another molecule within itself
functionalized with tetraphosphonate cavitands have been used to singularly detect sarcosine in water and urine solutions. Molecular recognition Freeman, Wade A. (1984)
Cavitand
Vitamin
adds a 1C unit to THF to yield 10-formyl-THF. Glycine, histidine, and sarcosine can also directly contribute to the THF-bound 1C pool. The antifolate
Folate
Chemical compound
data sheet (SDS) ChemicalBook Related compounds Related alkanoic acids Sarcosine Dimethylglycine Glycocyamine N-Methyl-D-aspartic acid beta-Methylamino-L-alanine
Creatine
Pharmaceutical compound
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
CX1739
Protein-coding gene in the species Homo sapiens
2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN 1cwk: HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN 1cwl:
Peptidylprolyl_isomerase_A
Blue dye also used as a medication
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Methylene_blue
Psychoactive substance found in plants in the family Apocynaceae
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Ibogaine
Organic compounds that influence the properties of biological fluids
osmoprotectants include trimethylamine N-oxide (TMAO), dimethylsulfoniopropionate, sarcosine, betaine, glycerophosphorylcholine, myo-inositol, taurine, glycine, and
Osmolyte
Central nervous system stimulant
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Caffeine
Calcium channel blocker medication
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Nifedipine
Ubiquitous antioxidant compound in living organisms
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Glutathione
Cough suppressant and dissociative drug
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Dextromethorphan
Experimental antidepressant
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Osavampator
Chemical compound
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Piracetam
Chemical compound
1.883 Basicity (pKb) 12.114 Related compounds Related alkanoic acids Sarcosine Dimethylglycine Glycocyamine Creatine N-Methyl-d-aspartic acid Guanidinopropionic
Β-Methylamino-L-alanine
Human chromosome
exonuclease 4 RNF183: encoding protein Ring finger protein 183 SARDH: sarcosine dehydrogenase, mitochondrial SIT1: signaling threshold regulating transmembrane
Chromosome_9
Autoantibodies against liver mitochondria, indicating primary biliary cholangitis
– outer mitochondrial membrane M6 – outer mitochondrial membrane M7 – sarcosine dehydrogenase M8 – outer mitochondrial membrane M9 – glycogen phosphorylase
Anti-mitochondrial_antibody
Supramolecular structures held together other than by covalent bonds
functionalized with tetraphosphonate cavitands have been used to singularly detect sarcosine in water and urine solutions. Traditionally, chemical sensing has been
Host–guest_chemistry
Chemical compound
catalytic oxidation of N-methylaminoethanol, the non-proteinogenic amino acid sarcosine is obtained. N-methylaminoethanol plays a role as a building block for
N-Methylethanolamine
Pharmaceutical drug
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Dextromethorphan/quinidine
Benzodiazepine drug
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Bromazepam
Chemical compound
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Dehydroepiandrosterone
Chemical compound
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Tert-Butyl_alcohol
Medication used to treat dyskinesia
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Amantadine
Organic compound with a –C≡N functional group
alcohols in the Pinner reaction. with amines, e.g. the reaction of the amine sarcosine with cyanamide yields creatine with arenes to form ketones in the Houben–Hoesch
Nitrile
Medication used to treat Alzheimer's disease
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Memantine
Chemical element with atomic number 54 (Xe)
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Xenon
Colourless non-flammable greenhouse gas
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Nitrous_oxide
Calcium channel blocker medication
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Verapamil
Pain medication of the opiate family
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Morphine
Medication used to treat ADHD
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
Atomoxetine
Chemical compound
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Β-Alanine
Chemical compound
L-Threonine MDL-27531 Milacemide Picolinic acid Propofol Quisqualamine Sarcosine Taurine Positive modulators: Alcohols (e.g., brometone, chlorobutanol
Nipecotic_acid
Chemical compound
L-Alanine L-Serine Milacemide Neboglamine (nebostinel) Rapastinel (GLYX-13) Sarcosine; Polyamine site agonists: Neomycin Spermidine Spermine; Other positive
2F-NENDCK
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