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Bile acid
Deoxycholic acid is a bile acid. Deoxycholic acid is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. The two primary
Deoxycholic_acid
Steroid acid in the bile of animals
derivatives, deoxycholic acid and lithocholic acid, are also found, with derivatives of cholic, chenodeoxycholic and deoxycholic acids accounting for
Bile_acid
Medication and metabolite of cholesterol
cells. While some bile acids are known to be colon tumor promoters (e.g. deoxycholic acid), others such as ursodeoxycholic acid are thought to be chemopreventive
Ursodeoxycholic_acid
Non-invasive non-surgical technique
results with the pressurized injection system. In the United States, deoxycholic acid, under the brand name Kybella, is approved by the Food and Drug Administration
Mesotherapy
Dark greenish-brown fluid aiding in the digestion of fats
Cholic acid Chenodeoxycholic acid Glycocholic acid Taurocholic acid Deoxycholic acid Lithocholic acid Medicine portal Animals portal Bile acid sequestrant
Bile
Chemical compound
sarcomas were induced in mice with injection of deoxycholic acid. The salts and esters of apocholic acid are known as apocholates.[citation needed] Apocholate
Apocholic_acid
Physiological molecule and therapeutic drug
Hyaluronic acid (/ˌhaɪ.əljʊəˈrɒnɪk/; HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed
Hyaluronic_acid
Yellowish crystalline bile acid
taurocholic acid in newborn rats is 380 mg/kg.[citation needed] Deoxycholic acid Anwer, M. Sawkat (2004). "Cellular regulation of hepatic bile acid transport
Taurocholic_acid
Chemical compound
Glycodeoxycholic acid is a bile acid derived from deoxycholic acid and glycine. Except where otherwise noted, data are given for materials in their standard
Glycodeoxycholic_acid
Cosmetic surgery to remove unwanted adipose tissue
substances, such as deoxycholic acid (branded as Kybella in the United States), directly into the targeted fat tissue. Deoxycholic acid is a naturally occurring
Fat_removal_procedures
Substance that stimulates the immune system
hormone and vitamin D. Some publications point towards the effect of deoxycholic acid (DCA) as an immunostimulant of the non-specific immune system, activating
Immunostimulant
target of the cytotoxic bile acid deoxycholic acid. The mitochondrial membranes were more sensitive to deoxycholic acid induced structural changes than
Mitochondrial outer membrane permeabilization
Mitochondrial_outer_membrane_permeabilization
One of the main bile acids
group to produce cholic acid. Some other mammals have muricholic acid or deoxycholic acid rather than chenodeoxycholic acid. It occurs as a white crystalline
Chenodeoxycholic_acid
Chemical compound
reactive compounds. It is typically stored with a stabilizer in a weakly acidic solution in an opaque bottle. Hydrogen peroxide is found in biological systems
Hydrogen_peroxide
Chemical compound
differs from deoxycholic acid in that the 6α-hydroxyl is in the 12 position in the former. The 6α-hydroxyl group makes HDCA a hydrophilic acid, a property
Hyodeoxycholic_acid
Community of microorganisms in the gut
of colorectal cancer. The secondary bile acid deoxycholic acid, produced from the primary bile acid cholic acid by the gut microbiota, is elevated in the
Gut_microbiota
Medical condition
of deoxycholic acid, a product of bile acid alteration by certain gut microbes, and these microbes are increased with obesity. The excess deoxycholic acid
Liver_disease
Topics referred to by the same term
5-Dimethoxy-4-chloroamphetamine, a psychedelic amphetamine DOC, Deoxycholic acid, a bile acid Day-old cockerel, a term in falconry Diesel Oxidation Catalyst
Doc
Nonsteroidal anti-inflammatory drug
United States, with more than 9 million prescriptions. It is available as its acid or in two salts, as either diclofenac sodium or potassium. Diclofenac is
Diclofenac
Surfactants with cleansing properties
surfactants are produced annually for the domestic markets. Bile acids, such as deoxycholic acid (DOC), are anionic surfactants produced by the liver to aid
Detergent
Species of bacterium
unconjugated secondary bile acids, like deoxycholic acid and lithocholic acid respectively. Primary bile acids are conjugated to either taurine or glycine
Clostridium_scindens
Chemical compound
prepare actodigin. In Lednicer's book on steroids, it is made from deoxycholic acid. http://www.sigmaaldrich.com/catalog/ProductDetail.do
Digitoxigenin
Index of chemical compounds with the same molecular formula
refer to: Chenodeoxycholic acid, a bile acid Deoxycholic acid, a bile acid Hyodeoxycholic acid, a bile acid Ursodiol, a bile acid This set index page lists
C24H40O4
Medical condition
well known risk factor for hypopharyngeal cancer, in combination with deoxycholic acid in bile reflux, promotes hypopharyngeal squamous cell carcinoma via
Hypopharyngeal_cancer
Cancer of the colon or rectum
of bile acids, particularly deoxycholic acid, are higher. Higher fecal concentrations of the bile acids cholic acid and chenodeoxycholic acid are associated
Colorectal_cancer
Body hair removal
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Hair_removal
Bears kept in captivity to harvest their bile
L, Schoonjans K, Keely SJ (September 2017). "Bile acids deoxycholic acid and ursodeoxycholic acid differentially regulate human β-defensin-1 and −2 secretion
Bile_bear
American scientist and entrepreneur
including alogliptin, trelagliptin, gemigliptin, plazomicin, and deoxycholic acid. David earned an A.B. in Biology from Harvard University and a Ph.D
Nathaniel_David
Process of cells digesting parts of themselves
diet is linked to elevated levels of bile acids in the colon, particularly deoxycholic acid. Deoxycholic acid induces autophagy in non-cancer colon epithelial
Autophagy
Chemical compound
4-Aminobenzoic acid (also known as para-aminobenzoic acid or PABA because the two functional groups are attached to the benzene ring across from one another
4-Aminobenzoic_acid
Chemical compound
Calcium gluconate is the calcium salt of gluconic acid and is used as a mineral supplement and medication. As a medication it is used by injection into
Calcium_gluconate
Chemical compound
Cromoglicic acid (INN)—also referred to as cromolyn (USAN), cromoglycate (former BAN), or cromoglicate—is traditionally described as a mast cell stabilizer
Cromoglicic_acid
Class of steroid hormones
process that started with deoxycholic acid, which was extracted from ox bile. The low efficiency of converting deoxycholic acid into cortisone led to a
Corticosteroid
Agent directly involved in causing cancer
bile acids as an important factor in colon cancer. Twelve studies (summarized in Bernstein et al.) indicate that the bile acids deoxycholic acid (DCA)
Carcinogen
Controversial cosmetic procedure
Lipostabil injection. In 2015, the US Food and Drug Administration approved deoxycholic acid (branded as Kybella) for use as an injection lipolysis product when
Injection_lipolysis
Species of bacterium
jejuni. When C. jejuni is grown in a medium containing the bile acid deoxycholic acid, a component of bile, the DNA of C. jejuni is damaged by a process
Campylobacter_jejuni
Malignant neoplastic disease of the esophagus
adenocarcinoma. Bile reflux containing unconjugated bile acids, including deoxycholic acid and chenodeoxycholic acid, appears to contribute to esophageal adenocarcinoma
Esophageal_cancer
Bacteriophage genome that is integrated into a bacterial cell
prophage release from the bacterial chromosome is common. The presence of deoxycholic acid in the intestinal environment can promote induction of C. difficle
Prophage
Precancerous tissue formation in the esophagus
Individuals with GERD and BE are exposed to high concentrations of deoxycholic acid that has cytotoxic effects and can cause DNA damage. This mechanism
Barrett's_esophagus
Disease caused by C. difficile bacteria
multiply into vegetative cells in the colon. The presence of the bile acid deoxycholic acid in the intestinal environment can promote the induction of C. difficile
Clostridioides difficile infection
Clostridioides_difficile_infection
Dehydroepiandrosterone (DHEA) Deoxycholic acid DON (DeoxyNivalenol) Deoxyribofuranose Deoxyribose Deoxyribonucleic acid (DNA) Dextran Dextrin Dicer Dihydrotestosterone
List_of_biomolecules
Medical condition
decreased abundance of secondary bile acids such as lithocholic acid and deoxycholic acid. The human microbiota consists of 10–100 trillion microorganisms. Several
Inflammatory_bowel_disease
Chemical compound with both hydrophilic and lipophilic properties
composed of a polar-phosphate based head group and two hydrophobic fatty acid chains. Phospholipid bilayers are the major structural component of cell
Amphiphile
Pharmaceutical compound
activity in hair follicle stem cells (HFSCs). As a result of this, lactic acid levels and glycolysis increase within the cells and more energy for cellular
Suvomipic
State in which a body lacks enough iron to supply its needs
mediated, in part, through altered bile acid production including an increase in deoxycholic acid, a secondary bile acid implicated in colon cancer and other
Iron_deficiency
Type of medicine which removes warts
swelling and hydrolysis of skin), salicylic acid, urea, lactic acid, allantoin, glycolic acid, and trichloroacetic acid. While cytostatic agents such as zinc
Keratolytic
Skin disease
topically to the affected area. Keratolytics include urea, salicylic acid, coal tar, lactic acid, pyrithione zinc and propylene glycol. Coal tar shampoo formulations
Seborrhoeic_dermatitis
Impaired flow of bile from the liver to the small intestine
microbes into deconjugated secondary bile acids, predominantly deoxycholic acid (DCA) and lithocholic acid (LCA). DCA and LCA are then reabsorbed into
Cholestasis
Monoclonal antibody
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Lebrikizumab
Flow of stomach contents into the throat (larynx and pharynx)
2022). "Noxious Combination of Tobacco Smoke Nitrosamines with Bile, Deoxycholic Acid, Promotes Hypopharyngeal Squamous Cell Carcinoma, via NFκB, In Vivo"
Laryngopharyngeal_reflux
Drug used to treat allergic diseases
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Dupilumab
Antiandrogen medication
progesterone [57-83-0] oxidizes the 17-acetyl group into a carboxylic acid to give etienic acid [302-97-6] (2). A Schotten–Baumann reaction with tert-butylamine
Finasteride
Steroidal antiandrogen and antimineralocorticoid
acid γ-lactone 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17β-carbolactone 3-(3-Oxo-7α-acetylthio-17β-hydroxyandrost-4-en-17α-yl)propionic acid lactone
Spironolactone
Concept in toxicology
bile acids are implicated by substantial evidence as an important genotoxic factor in colon cancer. In particular, the bile acid deoxycholic acid causes
Genotoxicity
Organ system cancer located in gastrointestinal tract
important factor in the development of colorectal cancer. The bile acid deoxycholic acid is increased in the colonic contents of humans consuming a high
Gastrointestinal_cancer
Subdiscipline of microbiology that studies bacteria
such as salmonella, XLD agar which contains, among other ingredients deoxycholic acid is used. Bacteria were first observed by the Dutch microscopist Antonie
Bacteriology
Chemical compound
which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone. A second route involves hydroxylation of
Hydroquinone
Chemical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Zinc_pyrithione
Medication to treat hair loss
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Ritlecitinib
Chemical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Monobenzone
Medication to treat high blood pressure and alopecia
conversion of minoxidil into its active form minoxidil sulfate. Salicylic acid is also a sulfotransferase inhibitor and could likewise affect the effectiveness
Minoxidil
Antiseptic solution
adverse events, and the combination of sodium hypochlorite and hypochlorous acid in very low concentration is significantly superior for wound healing. Consequently
Povidone-iodine
Chemical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Sofpironium_bromide
Immunosuppressive drug
L-pipecolic acid formed from L-lysine and catalyzed through fkbL enzyme synthesizes with the molecule from the module 10. The process of L-pipecolic acid synthesis
Tacrolimus
Oils with fatty acids that has been studied to prevent dermatitis includes: Corn oil: Linoleic acid (LA) Fish oil: Eicosapentaenoic acid (EPA) and docosahexaenoic
Management_of_hair_loss
Quaternary ammonium surfactant and antiseptic agent
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Cetrimide
Claveliimonas bilis is a newly described species of anaerobic, deoxycholic acid-producing bacteria belonging to the family Lachnospiraceae. First isolated
Claveliimonas_bilis
Damage in DNA which occurs naturally
aneuploidy and chromosome breakage. High-normal levels of the bile acid deoxycholic acid cause apoptosis in human colon cells, but may also lead to colon
DNA damage (naturally occurring)
DNA_damage_(naturally_occurring)
Topical decongestant
Müller-Calgan H, "2-(2,6-dimethyl-3-hydroxy-4-tert-butyl-benzyl)-2-imidazoline, and acid addition salts thereof, and process for their manufacture", issued 23 November
Oxymetazoline
Medication
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Oclacitinib
Monoclonal antibody
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Tralokinumab
Chemical compound
of the class of benzoxaboroles characterized by the presence of a boronic acid hemiester with a phenolic ether and a nitrile. Crisaborole crystallizes into
Crisaborole
Pharmaceutical drug classification
Aminobenzoate potassium D11AX24 Deoxycholic acid D11AX25 Hydrogen peroxide D11AX26 Caffeine D11AX27 Oxymetazoline D11AX52 Gamolenic acid, combinations D11AX57 Collagen
ATC_code_D11
Androgen and anabolic steroid
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Metandienone
Chemical compound
Alitretinoin, or 9-cis-retinoic acid, is a form of vitamin A. It is also used in medicine as an antineoplastic (anti-cancer) agent developed by Ligand
Alitretinoin
Drug or agent applied to the skin to control seborrhea or seborrheic dermatitis
zinc pyrithione, corticosteroids, imidazole antifungals, and salicylic acid are common anti-seborrheics. An ideal antiseborrheic should have the following
Anti-seborrheic
Medication
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Atinvicitinib
Chemical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Brimonidine
Antifungal chemical compound
ketoconazole is best absorbed at highly acidic levels, so antacids or other causes of decreased stomach acid levels will lower the drug's absorption.
Ketoconazole
Immunosuppressive drug
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Pimecrolimus
Pharmaceutical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Finasteride/latanoprost/minoxidil
Finasteride/latanoprost/minoxidil
Medication for parasite infestations
1038/ncomms2924. PMID 23728580. Kim SG, Kim BK, Kim K, Fang S (December 2016). "Bile Acid Nuclear Receptor Farnesoid X Receptor: Therapeutic Target for Nonalcoholic
Ivermectin
Solid mineral mass formed in the gastrointestinal system
calcium phosphate, and calcium carbonate and reports choleic acid. Deoxycholic acid and cholic acid have also been reported. In simple cases of obstruction
Enterolith
Antiandrogen and hormone replacement medication
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Dutasteride
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Magnesium sulfate (medication)
Magnesium_sulfate_(medication)
Association between obesity and risk of cancer
alterations of the gut microbiota that result in an increased level of deoxycholic acid, a gut bacterial metabolite considered to cause DNA damage leading
Obesity_and_cancer
Investigational hair loss drugs
inhibitor SCO-240 – oral – alopecia – somatostatin receptor 5 modulator Squaric acid dibutyl ester (SQX-770) – topical – alopecia areata – immunomodulator VDAA
List of investigational hair loss drugs
List_of_investigational_hair_loss_drugs
Chemical compound
quickly broken down into shorter peptide fragments and amino acids. Afamelanotide has the amino acid sequence; Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Afamelanotide
Chemical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Eflornithine
Process whereby cells acquire the properties of cancer
rural South Africans increased their secondary bile acids (including the carcinogenic deoxycholic acid) by 400%, and also changed the colonic microbiota
Malignant_transformation
Chemical compound
Lithium succinate (C4H4Li2O4), the dilithium salt of succinic acid, is a drug used in the treatment of seborrhoeic dermatitis and proposed for the treatment
Lithium_succinate
American research chemist (1899–1975)
synthesis developed by chemist Lewis Sarett, starting with deoxycholic acid from cattle bile acids. On September 30, 1949, Julian announced an improved process
Percy_Lavon_Julian
Pharmaceutical drug classification
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
ATC_code_D
Chemical compound
of 5 : 6-dimethyl-1 : 2-benzanthraquinone, a degradation product of deoxycholic acid". Journal of the Chemical Society. p. 428. Jacobs SA, Harvey RG (1981)
Methylcholanthrene
Monoclonal antibody
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Lokivetmab
Monoclonal antibody
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
Nemolizumab
Chemical compound
bile acid metabolic processes which lead to an increase in multiple acids such as deoxycholic acid, glycocholic acid, taurochenodeoxycholic acid, tauromuricholic
2,3,7,8-Tetrachlorodibenzofuran
2,3,7,8-Tetrachlorodibenzofuran
Polymeric drug carrier
temperature, and redox conditions. Micelles composed of dextran grafted with deoxycholic acid or polycaprolactone via a disulfide bond are responsive to a redox
Dextran_drug_delivery_systems
Pharmaceutical compound
Cromoglicic acid Delgocitinib Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium bromide Glycopyrronium tosylate Hyaluronic acid Hydrogen
AB-103
Chemical compound
treatment of osteoarthritis. It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration
Oxaceprol
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DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
Male
English
 English form of Welsh Kai, KAY means "lord." In Arthurian legend, this is the name of one of the first Knights of the Round Table. He was the son of Sir Ector, the foster brother of King Arthur, and is noted for having an acid tongue and boorish behavior, but mostly for trying to take credit when Arthur pulled the sword from the stone. Compare with another form of Kay.Â
Girl/Female
Latin
Named for Venus.
DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
DEOXYCHOLIC ACID
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