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Process of biological interventions on extracted fragments of organisms
Ex vivo (Latin for 'out of the living') is a term for biological studies involving tissues, organs, or cells maintained outside their native organism
Ex_vivo
Process of testing biological interventions on whole, living organisms
exact natural state In vivo ("in the living"), with a living being (usually the whole organism, in a controlled environment) Ex vivo ("out of the living")
In_vivo
Surgical technique
Ex vivo reconstruction, short for ex vivo renal artery reconstruction and autotransplantation, is a technique mainly used for complex disease involving
Ex_vivo_reconstruction
Medical technology
viruses (AAVs) and lentiviruses for performing gene insertions, in vivo and ex vivo, respectively. AAVs are characterized by stabilizing the viral capsid
Gene_therapy
Type of vaccine
response against cancer cells in mice. The first human clinical trial using ex vivo dendritic cells transfected with mRNA encoding tumor antigens (therapeutic
MRNA_vaccine
Theory of life arising from non-living matter
Generation of Animals), he denied spontaneous generation with the motto omnia ex ovo ("everything from eggs"). The ancient beliefs were subjected to testing
Spontaneous_generation
Contraction of the uterus
donated human uterine tissues can be used to measure uterine contractility ex vivo. In these experiments, sections of myometrium are set up in an organ bath
Uterine_contraction
Protein–protein interaction screening refers to the identification of Protein–protein interaction with high-throughput screening methods such as computer-
Protein–protein interaction screening
Protein–protein_interaction_screening
Rare autosomal-recessive human disease
in human and mouse fibroblasts. PPL-001 (Papillon Therapeutics) is an ex vivo gene-edited cell therapy in preclinical development. CRISPR Therapeutics
Friedreich's_ataxia
Canadian surgeon
transplantation. The solution is made from low-potassium dextran and is used in the Ex Vivo.[citation needed] The LPD solution is applied in both the Toronto lung
Shaf_Keshavjee
Route by which substances can enter the body through the skin
of this ex vivo technique is the isolated perfused porcine flap. This method was first described in 1986 as a humane alternative to in vivo animal testing
Absorption_(skin)
Technique involving the temporary sharing of circulatory systems for medical purposes
rehabilitate injured donor organs and bioengineer transplantable grafts ex vivo. In the early 1950s, open-heart surgery was limited by the lack of extracorporeal
Cross-circulation
Donor lung preservation technique
Ex vivo lung perfusion (abbreviated EVLP) is a form of machine perfusion aimed at sustaining the active aerobic cellular metabolism of donor lungs outside
Ex_vivo_lung_perfusion
Describing conditions present in a non-laboratory environment
non-laboratory environment, to differentiate it from in vivo (experiments on live organisms in a lab) and ex vivo (experiments on cultivated cells isolated from
In_natura
through leukapheresis and after maturation/stimulation of these precursors ex vivo, fully mature DCs are injected back into the patient. There are different
Dendritic cell-based cancer vaccine
Dendritic_cell-based_cancer_vaccine
due to major improvements in mass spectrometry and separation science. Ex vivo blood stimulation is the process by which researchers can analyse the immunological
Biomarker_discovery
Pharmaceutical compound
to stimulate hair growth in genetically modified mice in vivo and in excised human skin ex vivo. Another related approach to promoting hair growth is application
PP405
Pathogenic type of misfolded protein
2-D crystalline arrays have also been reported at lower resolution in ex vivo preparations of prions. In the prion amyloids, the glycolipid anchors and
Prion
Experimental lentiviral approach to generating CAR-T cells inside the body
than modifying cells ex vivo and reinfusing them. Conventional autologous CAR-T therapy generally involves leukapheresis, ex vivo gene transfer, cell expansion
Targeted lentiviral delivery for in vivo CAR T-cell generation
Targeted_lentiviral_delivery_for_in_vivo_CAR_T-cell_generation
Optical imaging modality
Wax conducted a couple of qualitative studies. Firstly, they examined ex-vivo porcine ear skin using DA-OCT and traditional OCT. The epidermis appears
Dual-axis optical coherence tomography
Dual-axis_optical_coherence_tomography
System to collect samples for cancer tests
based cancer detection and diagnosis system that can be used for ex vivo and in vivo tissue sample analysis. The system collects biological molecules
MasSpec_Pen
American biotechnology company
disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy by using engineered human cells
Intellia_Therapeutics
American gene editing company
Carolina. Founded in 2006, Precision is focused on developing both in vivo and ex vivo gene editing therapies using its proprietary "ARCUS" genome editing
Precision_BioSciences
Therapy and pharmacy for the common infectious disease
Berenson RJ, Bonyhadi M (2004). "Optimization of human T-cell expansion ex vivo using magnetic beads conjugated with anti-CD3 and Anti-CD28 antibodies"
Treatment_of_influenza
Latin term meaning outside a natural biological environment
result, anything that is not in vivo is in vitro. This includes animal organ cultures, animal tissue cultures (ex vivo), animal cell cultures, prokaryotic
In_vitro
Pharmaceutical compound
causing them to move from the telogen phase to the anagen phase. In human ex vivo scalp model studies, ABS-201 stimulated hair regrowth, prolonged anagen
ABS-201
Topics referred to by the same term
Look up vivo, vivő, or vívó in Wiktionary, the free dictionary. Vivo or VIVO may refer to: Vivo (technology company), a Chinese consumer electronics company
Vivo
Surgically moving tissue to a different part of the same body
selected organs is often preceded by ex vivo (also bench, back-table, or extracorporeal) surgery. For example, ex vivo liver resection and autotransplantation
Autotransplantation
etc.) that cannot be manipulated in vivo. M Plodinec et al.[citation needed] extended this work using ex vivo breast cancer biopsies that were analysed
Physical_oncology
American biotechnology company
formed in 2002. Crown Bioscience is known for capabilities in in vivo, in vitro, ex vivo, and in silico preclinical models. It works with companies in the
Crown_Bioscience
Pharmaceutical compound
UM171 is a small molecule that was initially developed to facilitate the ex vivo expansion of hematopoietic stem and progenitor cells (HSPCs), but is now
UM171
Device for artificial gestation
of these technologies forward and combine them to establish the first ex vivo fetal maturation system for clinical use. This project, coordinated by
Artificial_womb
combinations. These techniques can be performed either in vivo, ex vivo, or in vitro. Ex vivo techniques enable a more accurate count of the T cells in
T-cell_depletion
Variety of white blood cells
for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments. TH2 and ILC2 cells both express the transcription
Eosinophil
Species of shrub endemic to New Zealand
which causes pungency on the tongue in concentrations as low as 0.1 μg. An ex vivo study used a horopito and aniseed mixture (Kolorex) to inhibit the growth
Pseudowintera_colorata
Main inhibitory neurotransmitter in the mammalian brain
rat pineal glands (removed from the body, ex vivo). It also depolarizes the GnRH-producing neurons ex vivo via their GABAA receptors. Melatonin modulates
GABA
Measure the amount of a target entity
vivo, whole organism (e.g. mouse or other subject injected with a drug) ex vivo body part (e.g. leg of a frog) ex vivo organ (e.g. heart of a dog) ex
Assay
Bulge in the wall of a blood vessel
reliable approximation of dissection layers in sutureless aortic anastomosis. Ex vivo experimental study". Interactive Cardiovascular and Thoracic Surgery. 10
Aneurysm
Measurement and interpretation of the polarization of transverse waves
light–matter interactions. Early studies demonstrated the feasibility of ex vivo cancer characterization using Mueller polarimetric imaging, for example
Polarimetry
Video game publisher
Interactive Windows Fragile Existence Fragile Continuum Windows TBA Espiocracy Ex Vivo Studios Windows, Mac, Linux Darkwood 2 Ice-Pick Lodge Windows, Xbox Series
Hooded_Horse
American biotechnology company
transplantation of autologous CD34+ stem cells modified by prime editing ex vivo. PM359 also received Rare Pediatric Disease and Orphan Drug designations
Prime_Medicine
Academic journal
tissue, target organ, and whole body level, both in vivo (by all routes of exposure) and in vitro/ex vivo. The current editor-in-chief is Philip W. Harvey
Journal_of_Applied_Toxicology
Biotechnology for gene delivery
viral vectors can be performed by in vivo delivery by directly administering the vector to the patient, or ex vivo by extracting cells from the patient
Viral_vector
Preparation technique for ex vivo experiments
The Langendorff heart or isolated perfused heart assay is an ex vivo technique used in pharmacological and physiological research using animals and also
Langendorff_heart
Thin sections of lung tissue used in respiratory research
stimuli. Ensuring the viability of Precision-cut Lung Slices (PCLS) during ex vivo maintenance presents several challenges. Typically, PCLS are submerged
Precision_cut_lung_slices
(opinion), The New York Times, 9 August 2025 (without the 'ex'). Retrieved 2025-08-10.; "ex proprio vigore", The New York Times, 10 March 1900, p. 8 facsimile
List_of_Latin_phrases_(E)
(THAM). It has been used experimentally, for instance to study arteries ex vivo, in Langendorff heart preparations, and during isolated muscle testing
Krebs–Henseleit_solution
Biological process
and the repair of damaged tissues. Later, more extensive in vitro and ex vivo studies have shown that macrophage phenotypes are much more diverse, overlapping
Macrophage_polarization
Human with cells of different genotypes
contribution of human extended pluripotent stem cells to monkey embryos ex vivo". Cell. 184 (8): 2020–2032.e14. doi:10.1016/j.cell.2021.03.020. PMID 33861963
Human_chimera
Method of gene modification
methods of gene therapy using lentiviruses have been proposed. In the ex vivo methodology, cells are extracted from a patient and then cultured. A lentiviral
Lentiviral vector in gene therapy
Lentiviral_vector_in_gene_therapy
together, and measuring the reaction that occurs. Technically, it is an ex-vivo cellular immune assay that occurs between two allogeneic lymphocyte populations
Mixed_lymphocyte_reaction
Hypothesized microbiome in the brain
technologies, some scientists have claimed to identify microbial RNA in ex vivo brain tissue, including some healthy brains. However, critics argue that
Brain_microbiome
Latin phrase that translates literally to 'on site'
e.g., laboratory experiments), in vivo ('within the living', e.g., experiments on living organisms), and ex vivo ('out of the living', e.g., experiments
In_situ
Chemical compound
slices ex vivo. Similarly, EPPTB enhances electrically evoked dopamine release in nucleus accumbens (NAcc) but not dorsal striatum (DStr) slices ex vivo. However
EPPTB
Group of brain diseases induced by prions
PMID 36028585. Artikis E, Kraus A, Caughey B (August 2022). "Structural biology of ex vivo mammalian prions". The Journal of Biological Chemistry. 298 (8) 102181
Transmissible spongiform encephalopathy
Transmissible_spongiform_encephalopathy
Genetically engineered T cell
expression. However, in vivo CAR T therapy might mitigate some of the associated risks of systemic toxicities of classic ex vivo CAR T therapy like cytokine
CAR_T_cell
Chemical compound
Despite detection of gut-produced folate being incorporated into mammals, ex vivo folate synthesis capacity of fecal bacteria have no correlation with the
4-Aminobenzoic_acid
Menstrual hygiene device, an elastomeric cup worn inside the vagina to catch menses
consulting a doctor. The stated capacity of menstrual cup is generally measured ex vivo (outside the body). It is the volume of fluid that will fill the cup to
Menstrual_cup
Miniaturized and simplified version of an organ
Peng H, Poovaiah N, Forrester M, Cochran E, Wang Q (December 2014). "Ex Vivo Culture of Primary Intestinal Stem Cells in Collagen Gels and Foams". ACS
Organoid
Disease causing insufficient blood cells of all types
pro-inflammatory cytokines, such as interferon-γ and tumor necrosis factor-α. Ex vivo bone marrow models show an expansion of dysregulated CD8+ T cell populations
Aplastic_anemia
Species of bacterium
increases adherence of macrophages to endothelial cells in vitro and aortas ex vivo. However, most current research and data are insufficient and do not define
Chlamydia_pneumoniae
Cancer of epithelial cells with glandular origin or characteristics
"Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models". Disease Models & Mechanisms. 10 (2): 89–104. doi:10.1242/dmm
Adenocarcinoma
Gene therapy
gene into a recipient's blood-producing hematopoietic stem cells (HSC) ex vivo. The resulting engineered HSCs are then reintroduced to the recipient.
Betibeglogene_autotemcel
Medical procedure
infectious and immunologic risks), machine perfusion, and normothermic ex-vivo perfusion systems that have extended preservation intervals and improved
Transplantation_(medicine)
Culture of cells from fresh tissues
Primary cell culture is the ex vivo culture of cells freshly obtained from a multicellular organism, as opposed to the culture of immortalized cell lines
Primary_cell_culture
Paraphyletic group of mammals
Susan L. (2014-12-15). "Utility of cell viability assays for use with ex vivo vocal fold epithelial tissue". The Laryngoscope. 125 (5): E180–E185. doi:10
Big_cat
Nonionic surfactant and emulsifier used in food and cosmetics
texture that holds its shape as the ice cream melts. Research using an ex vivo model suggests it may "profoundly impact intestinal microbiota in a manner
Polysorbate_80
Method in molecular biology to make pores in cell membranes
role in the ex vivo manipulation of immune cells for the development of cell-based therapies, such as CAR T-cell therapy. Moreover, in vivo applications
Electroporation
British applied bioscientist
faecalis Demonstrates Pathogenicity through Increased Attachment in an Ex Vivo Polymicrobial Pulpal Infection. Infect Immun. Melling GE, Colombo JS, Avery
Alastair_J._Sloan
Human arterial disease
affected artery or if PTA does not resolve the issue.[citation needed] Ex vivo renal artery reconstruction is sometimes used for complex diseases where
Fibromuscular_dysplasia
Multipotent adult stem cells present in multiple tissues
myogenic (muscle) tissue and bone and named them mesenchymal stem cells. An ex vivo assay for examining the clonogenic potential of multipotent marrow cells
Mesenchymal_stem_cell
Medication for psoriasis and psoriatic arthritis
many others, and up-regulates the anti-inflammatory interleukin 10. In ex vivo models of arthritis, IL-12/IL-23p40 was specifically identified as a downstream
Apremilast
Solid form of plant resin
biocompatibility of rosin and rosin-based biomaterials has been examined in vitro and ex vivo. Treatment of rosin with sodium hydroxide or sodium carbonate converts
Rosin
Main anion present in sea water
precipitated via this reaction. Chlorided silver electrodes are commonly used in ex vivo electrophysiology. Chlorine can assume oxidation states of −1, +1, +3,
Chloride
phrase meaning "within likenesses." The phrase is used similarly to in vivo or ex vivo to denote the context of an experiment. In this case, the phrase denotes
In_simulacra
Pharmaceutical compound
the isolated rat brain stem ex vivo. However, it was 5-fold more potent than PPAP and selegiline as a MAE in rodents in vivo in terms of the minimum dose
Methylenedioxyphenylpropylaminopentane
Methylenedioxyphenylpropylaminopentane
Laboratory method involving brain slices
from various brain regions in isolation from the rest of the brain, in an ex-vivo condition. Brain tissue is initially sliced via a tissue slicer then immersed
Slice_preparation
Pleasurable phenomenon elicited via direct stimulation of specific brain regions
"Neurochemical correlates of brain-stimulation reward measured by ex vivo and in vivo analyses". Neuroscience and Biobehavioral Reviews. 13 (2–3): 99–104
Brain_stimulation_reward
Genetic disorder that causes early aging
skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies". Aging. 10 (7): 1758–1775. doi:10.18632/aging.101508. PMC 6075434
Progeria
Gene therapy medication
autologous CD34+ hematopoietic stem cell enriched population transduced ex vivo with a lentiviral vector encoding the human Wiskott–Aldrich syndrome gene
Etuvetidigene_autotemcel
Opening in the tip of the root of a tooth
visualization of accessory foramina is best achieved using high-resolution ex vivo imaging techniques like micro-CT, which is considered a gold standard for
Apical_foramen
TAAR1 agonist
core (NAcc) brain slices ex vivo. Conversely, RO5263397 by itself had no effect on dopamine overflow in rat NAcc slices ex vivo. RO5263397 alone has no
RO5263397
Transparent front layer of the eye
Krishnakumar, S.; Mori, Yuichi; Yoshioka, Hiroshi; Abraham, Samuel (2009). "Ex Vivo Cultivation of Corneal Limbal Epithelial Cells in a Thermoreversible Polymer
Cornea
with the T cells. Superparamagnetic particles can be used as aAPC for ex-vivo T cell expansion. These particles can be covalently bound to stimulatory
Artificial antigen-presenting cell
Artificial_antigen-presenting_cell
would otherwise cause further biological changes to the tissue sample ex vivo. Due to the permanent inactivation of enzymes, heat stabilization overcomes
Heat_stabilization
Culturing cells removed from the organism
to perform experiments and easily visualize the impact of tests. This ex vivo model requires a highly maintained environment in order to recreate original
Explant_culture
Specialized subtype of cytotoxic lymphocyte
long-term persistence for up to 3 months in vivo, high IFN-γ production, potent cytotoxic activity upon ex vivo restimulation, and protective memory responses
Adaptive_NK_cell
which can include in-vitro metabolite monitoring, in addition to in-vivo or ex-vivo MRI demonstrations. Conventional non 1H NMR and MRI signals can be
Parahydrogen-induced polarization
Parahydrogen-induced_polarization
American biotechnology company
"involving the delivery of genes or drugs via ex vivo, intratumoral and intramuscular electroporation... The ex-vivo patents are relevant to the delivery of
Inovio_Pharmaceuticals
Theoretical conditions under which life on the Earth might have begun
could enter, but not in a closed-lid jar. He concluded that: omne vivum ex vivo (All life comes from life). The experiment of French chemist Louis Pasteur
Primordial_soup
Surgical procedure that removes organs or tissues for reuse
hours, although shorter times generally improve outcomes. Advances in ex-vivo perfusion and normothermic preservation (e.g., portable organ perfusion
Organ_procurement
Moreover, Ag-specific tolerance in humans can be induced in vivo via vaccination with Ag-pulsed ex vivo generated tolerogenic DCs. For that reason, tolerogenic
Tolerogenic_dendritic_cell
Use of stem cells to treat or prevent a disease or condition
of these ailments. Fully mature human red blood cells may be generated ex vivo by hematopoietic stem cells (HSCs), which are precursors of red blood cells
Stem-cell_therapy
Activation or suppression of the immune system to treat disease
Rosenberg and colleagues in 1988, when they showed that TILs expanded ex vivo and reinfused into patients, together with high-dose interleukin-2, could
Immunotherapy
T- and natural killer (NK) cell-like phenotype. They are generated by ex vivo incubation of human peripheral blood mononuclear cells (PBMC) or cord blood
Cytokine-induced_killer_cell
Yellow food coloring
(2025). "Transient Optical Clearing Using Absorbing Molecules for Ex Vivo and In Vivo Imaging". Journal of Visualized Experiments (221). bioRxiv 10.1101/2025
Tartrazine
Gene therapy medication
treatment they rarely survive more than two years. Strimvelis is the first ex vivo autologous gene therapy approved by the European Medicines Agency (EMA)
Strimvelis
Dutch organisation
Charlotte (eds.), The Impact of Food Bioactives on Health: in vitro and ex vivo models, Cham (CH): Springer, pp. 37–46, doi:10.1007/978-3-319-16104-4_5
Netherlands Organisation for Applied Scientific Research
Netherlands_Organisation_for_Applied_Scientific_Research
Cell-surface glycoprotein
human hematopoietic stem cells and mesenchymal stem cells to bone marrow. Ex vivo glycan engineering of the surface of live cells has been used to enforce
CD44
naive T cells. They can be differentiated ex vivo and in vivo. The ways of Tr1 cells induction in vivo, ex vivo and in vitro differ and also envelop many
Type_1_regulatory_T_cell
EX VIVO
EX VIVO
EX VIVO
EX VIVO
Boy/Male
Indian, Tamil, Telugu
Lord Siva; Lord Hari
Girl/Female
Arabic, Australian, Iranian, Muslim, Parsi
Daughter of the Moon
Boy/Male
Hindu, Indian, Kannada, Telugu
Crystal Clear
Girl/Female
Hindu, Indian, Marathi
Bestowing Gifts; Kind
Girl/Female
Indian
Friendly
Boy/Male
Indian, Punjabi, Sikh
Of Pishawar
Boy/Male
Latin
Constant.
Girl/Female
Australian, Hindu, Indian
Flower
Boy/Male
Indian
God of Fame
Female
Italian
Italian form of French Mireille, MIRELLA means "to admire."
EX VIVO
EX VIVO
EX VIVO
EX VIVO
EX VIVO
n.
An offering to a church in fulfillment of a vow.
v. i.
To exist actually, or in the world of fact; to have ex/stence.
a.
Proceeding from office or authority.
pl.
of Ex officio
pl.
of Ex-voto
n.
An alkaloid ex tracted from the seeds of the vetch (Vicia sativa) as a white crystalline substance.