Search references for GENOME MINING. Phrases containing GENOME MINING
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Research process
Genome mining describes the exploitation of genomic information for the discovery of biosynthetic pathways of natural products and their possible interactions
Genome_mining
Group of chemical compounds
Franken, Philipp; Stallforth, Pierre (2023). "Ecological Niche-Inspired Genome Mining Leads to the Discovery of Crop-Protecting Nonribosomal Lipopeptides
Keanumycin
Natural organic compounds derived from a [C(O)–CH2] chain
advancements in biotechnology have allowed for the use of metagenomics and genome mining to find new polyketides using similar enzymes to known polyketides.
Polyketide
Species of actinobacterium
antifungal activity, was isolated from a coal mining site in Mongolia (Nalaikh coal mining site). The genome mining for biosynthetic gene clusters of secondary
Amycolatopsis_mongoliensis
Class of chemical compounds
1000 Da. The advent of next-generation sequencing methods has made genome mining of RiPPs a common strategy. In part due to their increased discovery
Ribosomally synthesized and post-translationally modified peptides
Ribosomally_synthesized_and_post-translationally_modified_peptides
interest in natural product drug discovery using machine learning and genome mining approaches. This work included the development of an open source tool
Exploratory_Science_Center
Japanese-British biologist
publications include; antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters Tanako, Eriko (2011). "antiSMASH: rapid
Eriko_Takano
Nepali chemist
protein engineering, and computational chemistry. His work includes genome mining, metabolomics and in silico studies of bioactive compounds. He has published
Niranjan_Parajuli
Study of genes found in the environment
Joint Genome Institute sequenced DNA extracted from an acid mine drainage system. This effort resulted in the complete, or nearly complete, genomes for
Metagenomics
Type of transposable element
of each Starship. Large-scale genome mining using the software has identified hundreds of Starships across fungal genomes. Horizontal gene transfer (HGT)
Starship_(genetics)
Class of enzymes
nerolidyl diphosphate. Hu Y, Chou WK, Hopson R, Cane DE (January 2011). "Genome mining in Streptomyces clavuligerus: expression and biochemical characterization
(+)-T-muurolol_synthase
Class of enzymes
nerolidyl diphosphate. Hu Y, Chou WK, Hopson R, Cane DE (January 2011). "Genome mining in Streptomyces clavuligerus: expression and biochemical characterization
(−)-delta-cadinene_synthase
Study of genetic variants in different individuals
In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals
Genome-wide_association_study
Chemical compound
first part of the sequence is established. Using transcriptome and genome mining and phylogenetic and homologous analysis, candidate genes were identified
Azadirachtin
German chemist
substances and to understand how they are assembled. Genetic methods (genome mining) and are primarily used to discover new active substances. To modify
Christian_Hertweck
Species of bacterium
associated with fermentation, stress response, and adhesion were found from genome mining of B. coagulans VHBAX-04. This strain also lacks pathogenicity-related
Heyndrickxia_coagulans
protease inhibitors produced by various genera of cyanobacteria. Recent genome mining has shown that the biosynthetic gene cluster responsible for microviridin
Microviridin
Species of fungus
Francis. p. 343. ISBN 978-0-412-17050-8. Yan D, Matsuda Y (April 2021). "Genome Mining-Driven Discovery of 5-Methylorsellinate-Derived Meroterpenoids from
Aspergillus_funiculosus
Software for understanding biological data
a bioinformatics resource for decoding RiPP chemical structures by genome mining. The RiPPMiner web server consists of a query interface and the RiPPDB
Machine_learning_in_biology
Species of bacterium
Dickschat, J. S.; Challis, G. L.; Leblond, P; Pernodet, J. L. (2014). "Genome mining of Streptomyces ambofaciens" (PDF). Journal of Industrial Microbiology
Streptomyces_ambofaciens
Family of enzymes
Zhu, Tianjiao; Li, Dehai; Gu, Qianqun; Li, Wenli (December 2018). "Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene
Cyclodipeptide_synthases
WK, Fanizza I, Uchiyama T, Komatsu M, Ikeda H, Cane DE (July 2010). "Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76
Avermitilol_synthase
Glycopeptide antibiotic used to treat various cancers
Yang D, Teng Q, Dong LB, Crnovčić I, Huang T, et al. (March 2017). "Genome Mining of Streptomyces mobaraensis DSM40847 as a Bleomycin Producer Providing
Bleomycin
Group of chemical compounds from fungi
Keller NP, Wang CC, Oakley BR (August 2016). "Resistance Gene-Guided Genome Mining: Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic
Fellutamide
Species of bacterium
Dickschat, J. S.; Challis, G. L.; Leblond, P; Pernodet, J. L. (2014). "Genome mining of Streptomyces ambofaciens" (PDF). Journal of Industrial Microbiology
Streptomyces_albofaciens
Chemical compound
A, Bibb M, Davis B (2010). "Dissecting tunicamycin biosynthesis by genome mining: cloning and heterologous expression of a minimal gene cluster". Chemical
Tunicamycin
Chemical compound
found to be a highly modified ribosomal peptide by a combination of genome mining and gene deletion studies. In ribosomal peptide synthesis, the final
Bottromycin
Scientific project at the European Bioinformatics Institute
Ensembl genome database project is a scientific project at the European Bioinformatics Institute, which provides a centralized resource for geneticists
Ensembl genome database project
Ensembl_genome_database_project
All genes of all strains in a clade
pan-genome (pangenome or supragenome) is the entire set of genes from all strains within a clade. More generally, it is the union of all the genomes of
Pan-genome
Streptomyces sp MA37, Norcardia brasiliensis, and Actinoplanes sp N902-109 by genome mining". ChemBioChem. 15 (3): 364–8. doi:10.1002/cbic.201300732. PMID 24449539
Fluorinase
Chemical compound
analogue, cyclothiazomycin C, was discovered in 2014 with the aid of genome mining, nucleophilic 1,4-addition labeling reactions, high resolution mass
Cyclothiazomycin
Organisms on the ocean's surface
Irigoien, Xabier (2014). "Carotenoid metabolic profiling and transcriptome-genome mining reveal functional equivalence among blue-pigmented copepods and appendicularia"
Ocean_surface_ecosystem
Family of fungi
Rachel A.; Aime, M. Catherine (January 2016). "Tales from the crypt: genome mining from fungarium specimens improves resolution of the mushroom tree of
Tricholomataceae
Chemical compound
represents an example of a “genome mining” approach. Cluster of genes encoding KLB biosynthetic pathway was found in genome database using low-level homology
Klebsazolicin
Enzyme
PMID 20039019. Wallwey C, Heddergott C, Xie X, Brakhage AA, Li SM (June 2012). "Genome mining reveals the presence of a conserved gene cluster for the biosynthesis
Chanoclavine-I_dehydrogenase
Genome database
of mining and extracting genomic data from the Ensembl databases in table formats like HTML, TSV, CSV or XLS. Release 45 (2019) of Ensembl Genomes has
Ensembl_Genomes
Class of bacterially produced peptide antibiotics
JJ, Kok J, Kuipers OP (July 2006). "BAGEL: a web-based bacteriocin genome mining tool". Nucleic Acids Research. 34 (Web Server issue): W273-9. doi:10
Bacteriocin
Protein family
PMID 27145839. Letzel AC, Pidot SJ, Hertweck C (November 2014). "Genome mining for ribosomally synthesized and post-translationally modified peptides
Radical_SAM_enzymes
Class of enzymes
protein-only RNase P: insights into the functional diversity of RNase P from genome mining". mBio. 16 (6): e0044925. doi:10.1128/mbio.00449-25. PMC 12153264. PMID 40298408
Ribonuclease_P
Class of enzymes
\rightleftharpoons } thalianol Fazio GC, Xu R, Matsuda SP (May 2004). "Genome mining to identify new plant triterpenoids". Journal of the American Chemical
Thalianol_synthase
Field of study in genomics
use of computational and statistical analysis to decipher biology from genome sequences and related data, including both DNA and RNA sequence as well
Computational_genomics
The Cancer Genome Project is part of the cancer, aging, and somatic mutation research based at the Wellcome Trust Sanger Institute in the United Kingdom
Cancer_Genome_Project
Class of enzymes
(2005). "Discovery of a thermostable Baeyer-Villiger monooxygenase by genome mining". Appl. Microbiol. Biotechnol. 66 (4): 393–400. doi:10.1007/s00253-004-1749-5
Phenylacetone_monooxygenase
Phylum of aquatic bacteria
Petersen, Jörn; Sikorski, Johannes; Jogler, Christian (2013-10-01). "From genome mining to phenotypic microarrays: Planctomycetes as source for novel bioactive
Planctomycetota
Research institution at the University of Michigan, Ann Arbor
a library of more than 45,000 natural product extracts, as well as genome mining and bioinformatics services.[citation needed] The LSI is a 235,000 square
Life_Sciences_Institute
Salinosporamide K from the Marine Bacterium "Salinispora pacifica" by Genome Mining Gives Insight into Pathway Evolution". ChemBioChem. 12 (1): 61–4. doi:10
Salinosporamide
Genus of bacteria
pharmaceutical or other industrial applications. In addition, with the genome mining of the Roseobacter, it was believed that Roseobacter are also capable
Roseobacter
Class of enzymes
enzyme requires Mg2+ for activity. Lin X, Hopson R, Cane DE (May 2006). "Genome mining in Streptomyces coelicolor: molecular cloning and characterization of
Epi-isozizaene_synthase
Drimentine G and its biosynthesis
Liu Z, Li T, Li H, Che Q, Zhu T, Li D, Gu Q, Li W (October 2018). "Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene
Drimentine_G
Genus of bacteria
Duggan BM, Dorrestein PC, Moore BS (May 2013). "Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica"
Salinispora
Peptide with Cancer Cell Migration Inhibitory Activity Discovered by the Genome Mining Approach". Journal of Natural Products. 81 (10): 2205–2211. doi:10.1021/acs
Complex_lasso_proteins
he was promoted to associate professor with tenure. Natural products Genome-mining Antibiotic resistance Mechanistic enzymology NIH Director’s New Innovator
Douglas_Mitchell_(scientist)
its action. Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE (March 2011). "Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases
Pentalenolactone_F_synthase
normal laboratory growth conditions. However, the new discipline of “genome mining” has been exploring ways to activate the expression of these “cryptic
Society for Industrial Microbiology and Biotechnology
Society_for_Industrial_Microbiology_and_Biotechnology
Discipline in genetics
focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as
Genomics
Type B lantibiotic produced by Streptomyces cinnamoneus
new lantibiotic cinnamycin B from Actinomadura atramentaria based on genome mining". Journal of Industrial Microbiology and Biotechnology. 43 (8): 1159–1165
Cinnamycin
Species of lichen-forming fungus
whole-genome sequencing. Genome mining of L. lupina has suggested extensive potential for secondary metabolism: one analysis of its published genome predicted
Letharia_lupina
Enzyme
1021/ja00167a059. Zhu D, Seo MJ, Ikeda H, Cane DE (February 2011). "Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative
Pentalenolactone_synthase
them. Genome mining for biosynthetic gene clusters (BGCs) has become an integral part of natural product discovery. The >200,000 microbial genomes now publicly
Metabolic_gene_cluster
Chemical compound
with three elongation modules and a lactonizing thioesterase domain. Genome mining of Streptomyces sp. BYK identified a scopranone biosynthetic gene cluster
Prescopranone
American pathologist (died 2021)
text-mining to the interpretation of gene expression profiles. In the 2001 Genome Issue of Nature, they followed the first publication of the human genome
Mark_Boguski
Family of large biological molecules
specific proteins. Many viruses encode their genetic information using an RNA genome. Some RNA molecules play an active role within cells by catalyzing biological
RNA
Whole genome bisulfite sequencing is a next-generation sequencing technology used to determine the DNA methylation status of single cytosines by treating
Whole genome bisulfite sequencing
Whole_genome_bisulfite_sequencing
Class of enzymes
alternative lactone. Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE (March 2011). "Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases
Neopentalenolactone D synthase
Neopentalenolactone_D_synthase
Professor of biology
develop a novel opportunity to discover natural product pathways through genome mining. The natural products include terpenes, which can be used in the pharmaceutical
Anne_Osbourn
Class of enzymes
alternative lactone. Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE (March 2011). "Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases
Pentalenolactone_D_synthase
Combustible sedimentary rock composed primarily of carbon
mines. The coal mining industry employs almost 2.7 million workers. More accidents occur during underground mining than surface mining. Not all countries
Coal
Computational analysis of large, complex sets of biological data
data mining, machine learning algorithms, and visualization. Major research efforts in the field include sequence alignment, gene finding, genome assembly
Bioinformatics
Field of biological research
Comparative genomics is a branch of biological research that examines genome sequences across a spectrum of species, spanning from humans and mice to a
Comparative_genomics
Outflow of acidic water from metal or coal mines
but is exacerbated by large-scale earth disturbances characteristic of mining and other large construction activities, usually within rocks containing
Acid_mine_drainage
Biomedical text analysis to extract relevant information and knowledge
Biomedical text mining (including biomedical natural language processing or BioNLP) refers to the methods and study of how text mining may be applied to
Biomedical_text_mining
Last phase of the Naqada culture of ancient Egyptian prehistory
4% ± 3.8%) was most closely related to known genomes from Neolithic Mesopotamia (dated to 9000–8000 BC). Genomes from the Neolithic/Chalcolithic Levant only
Naqada_III
Genus of viruses
transcribes the genome to produce messenger RNA (mRNA) for translation by host ribosomes to produce viral proteins and replicates the genome for progeny viruses
Hantavirus
Period in ancient Egyptian history (c. 2686–2181 BC)
a whole-genome genetic study was able to give insights into the genetic background of Old Kingdom individuals, by sequencing the whole genome of an Old
Old_Kingdom_of_Egypt
their own software, four major MODs--FlyBase, Saccharomyces Genome Database, Mouse Genome Database, and at or run off a Chado schema database. The Chado
Generic Model Organism Database
Generic_Model_Organism_Database
Indian microbioligist (1961–2025)
N. J.; Tamang, J. P. (2023). "Metagenomics and metagenome-assembled genomes mining of health benefits in Jalebi batter, a naturally fermented cereal-based
Jyoti_Prakash_Tamang
Species of fungus
produce industrial citric acid (CA). The A. niger ATCC 1015 genome was sequenced by the Joint Genome Institute in a collaboration with other institutions. Completed
Aspergillus_niger
Gene editing system
the journal Science in February 2025. The discovery involved structural mining for domains similar to the RNA binding domain of Cas9, which identified
TIGR-Tas
English TV presenter, journalist and broadcaster
column for the Daily Express. Malone was born on 14 October 1954 in the mining village of West Allotment, near Newcastle upon Tyne. She started her career
Carole_Malone
Technique of extracting metals from ores using prokaryotes or fungi
materials. The largest application currently being used is the treatment of mining waste containing iron, copper, zinc, and gold. It may also be useful in
Biomining
cost-effective procedure that will allow mining genomes of any species without prior knowledge of its genome structure. Restriction site associated DNA
Genotyping_by_sequencing
1915 novel by John Buchan
in London from Rhodesia early in 1914, having made a modest fortune as a mining engineer. Disillusioned with his uneventful life as a man about town, he
The_Thirty-Nine_Steps
Sequence Data Library (now known as European Nucleotide archive). Human Genome Project began in 1988. The project's goal was sequence and map all the genes
Sequence_database
Process of determining the nucleic acid sequence
identify and study the virus. Viral genomes can be based in DNA or RNA. RNA viruses are more time-sensitive for genome sequencing, as they degrade faster
DNA_sequencing
Subset of artificial intelligence
optimisation methods compose the foundations of machine learning. Data mining is a related field of study, focusing on exploratory data analysis (EDA)
Machine_learning
Genus of millipede
of this species is based on specimens discovered in drill holes bored by mining companies searching for minerals in the Great Western Woodlands of Australia
Eumillipes
the genome of the Anzick Clovis child, which sits squarely on the branch of Ancestral Native American peoples. No ancient or present-day genome (or mtDNA
Indigenous peoples of the Americas
Indigenous_peoples_of_the_Americas
Use of technology in agriculture
pp. 539–553. doi:10.1016/B978-0-323-91001-9.00016-5. ISBN 978-0-323-91001-9. Genome, Startup. "Startup Genome". Startup Genome. Retrieved 2024-06-17.
Agricultural_technology
oblanceolata, a fern ally plant, was found to contain the largest known genome. Promising results of health and medical research are reported: a mRNA vaccine-like
2024_in_science
Global disease outbreak since September 2023
by September 2023, with several of them being identified in Kamituga, a mining town in the province of South Kivu. A nationwide outbreak was reported in
2023–2026_mpox_epidemic
Field of science that uses cells for the creation of products
application of biotechnology to basic science (for example through the Human Genome Project) has also dramatically improved our understanding of biology and
Biotechnology
Statistical measure of a binary classification
sense of true negative rate would have little, if any, application in the genome analysis research area. Science portal Biology portal Medicine portal Brier
Sensitivity_and_specificity
Mummified corpse from the Atacama Desert, Chile
premature human fetus discovered in 2003 near La Noria, an abandoned nitrate-mining settlement in Chile's Atacama Desert. The remains attracted international
Atacama_skeleton
2025 American television series
genetics researcher Hobie McSorley (Nat Faxon) (who had hacked his own genome to make his own chest luminescent) to devise a non-FDA-approved treatment
Watson_(TV_series)
Miscegenation history
Bradley, D. G.; Bhak, J.; Pinhasi, R.; Manica, A. (2015). "Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa". Science. 350 (6262):
History_of_miscegenation
a certain level of analysis (processed data) or even offer online data mining. The table below gives an overview of databases for that serve specifically
List of databases for oncogenomic research
List_of_databases_for_oncogenomic_research
American bioinformatician
mining and machine learning, molecular simulation, and database design. His research group has a number of foci including annotating the human genome
Mark_B._Gerstein
Application of computer science in biology
computational biology, the Human Genome Project, officially began in 1990. By 2003, the project had mapped around 85% of the human genome, satisfying its initial
Computational_biology
Genus of coniferous evergreen trees
glauca, whole genome shotgun sequencing project". National Center for Biotechnology Information. 13 March 2015. "Picea glauca, whole genome shotgun sequencing
Spruce
Episode list for an American late-night talk show
commercial promoting safe sex in Norway Guests: Bobby Moynihan 136 17 CRISPR and genome editing July 1, 2018 (2018-07-01) 1.12 Other segment: Retirement of Anthony
List of Last Week Tonight with John Oliver episodes
List_of_Last_Week_Tonight_with_John_Oliver_episodes
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GENOME MINING
GENOME MINING
GENOME MINING
GENOME MINING
GENOME MINING
GENOME MINING
GENOME MINING
GENOME MINING
GENOME MINING
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