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Gamete-producing cell
A germ cell is any cell that gives rise to the gametes of an organism that reproduces sexually. In many animals, the germ cells originate in the primitive
Germ_cell
Medical condition
A germ cell tumor (GCT) is a neoplasm derived from primordial germ cells. Germ-cell tumors can be cancerous or benign. Germ cell tumors typically originate
Germ_cell_tumor
Primary layer of cells in embryonic development
A germ layer, primary germinal layer, or germinal layer is a primary layer of cells that forms during animal embryonic development. Germ layers form during
Germ_layer
Cancer originating in or on the ovary
cell types including epithelial cells, germ cells, and stromal cells. When these cells become abnormal, they can divide and form tumors. These cells can
Ovarian_cancer
Process in developmental biology
germ cell (PGC) migration is the process of distribution of primordial germ cells throughout the embryo during embryogenesis. Primordial germ cells are
Primordial germ cell migration
Primordial_germ_cell_migration
Haploid sex cell
gamete (/ˈɡæmiːt/ GAM-eet ), reproductive cell, or sex cell, is a haploid cell that fuses with another haploid cell during fertilization in organisms that
Gamete
Any biological cell forming the body of an organism
multicellular organism other than a gamete, germ cell, gametocyte or undifferentiated stem cell. Somatic cells compose the body of an organism and divide
Somatic_cell
Type of germ cell tumor
testicular torsion, or hydrops fetalis. They are a type of germ cell tumor (a tumor that begins in the cells that give rise to sperm or eggs). They are divided
Teratoma
Medical condition
disease, and previous history of testicular cancer. More than 95% are germ cell tumors which are divided into seminomas and non-seminomas. Other types
Testicular_cancer
The germ cell nest (germ-line cyst) forms in the ovaries during their development. The nest consists of multiple interconnected oogonia formed by incomplete
Germ_cell_nest
Biological concept
effect is one-way: germ cells produce somatic cells, and more germ cells; the germ cells are not affected by anything the somatic cells learn or any ability
Germ_plasm
Female reproductive organ that produces egg cells
organisms by which germ cells are formed, and it is likely an adaptation for removing DNA damage, especially double-strand breaks, from germ line DNA (see
Ovary
How an animal develops its sexual-reproduction cells
primordial germ cells, migrate to the location of the gonad, and form the germline of the animal. Cleavage in most animals segregates cells containing germ plasm
Germline_development
Medical condition
Mediastinal germ cell tumors are tumors that derive from germ cell rest remnants in the mediastinum. Germ cell tumors most commonly occur in the gonad
Mediastinal_germ_cell_tumor
Medical ultrasound examination of the scrotum
Primary intratesticular malignancy can be divided into germ cell tumors and non–germ cell tumors. Germ cell tumors are further categorized as either seminomas
Scrotal_ultrasound
Female reproductive cell
Human ova grow from primitive germ cells that are embedded in the substance of the ovaries. The ovum is one of the largest cells in the human body, typically
Egg_cell
Number of sets of chromosomes of a cell
haploid number are equal; in humans, both are equal to 23. When a human germ cell undergoes meiosis, the diploid 46 chromosome complement is split in half
Ploidy
Medical condition
associated risk factors for testicular germ cell tumor, the increase in risk of concurrent diagnosis of testicular germ cell tumor, or testicular carcinoma-in-situ
Testicular_microlithiasis
Male reproductive cell
unrepaired state as germ cells progress through DNA repair-competent phases of spermatogenic development. Such unrepaired DNA damages in sperm cells, after fertilization
Sperm
Cells of a multicellular organism that pass on genetic material to progeny
population of a multicellular organism's cells that develop into germ cells. In other words, they are the cells that form gametes (eggs and sperm), which
Germline
Medical condition
the anterior portion of the mediastinum can include thymoma, lymphoma, germ cell tumors including teratoma, thyroid tissue, and parathyroid lesions. Masses
Mediastinal_tumors
Haploid stage in the life cycle of plants and algae
of these cells is typically a germ cell and other cells may consist of a single tube cell which grows to form the pollen tube, sterile cells, and/or prothallial
Gametophyte
Medical condition
Sertoli cell-only syndrome (SCOS), also known as germ cell aplasia, is defined by azoospermia where the testicular seminiferous tubules are lined solely
Sertoli_cell-only_syndrome
Stem cell that gives rise to a gamete, such as a sperm or egg cell
Gametogonium (plural gametogonia) are stem cells for gametes located within the gonads. They originate from primordial germ cells, which have migrated to the gonads
Gametogonium
Medical condition
Germ cell neoplasia in situ (GCNIS) represents the precursor lesion for many types of testicular germ cell tumors. The term GCNIS was introduced with the
Germ_cell_neoplasia_in_situ
Ability of a cell to differentiate into other cell types
identical totipotent cells, which can later develop into any of the three germ layers of a human (endoderm, mesoderm, or ectoderm), or into cells of the placenta
Cell_potency
Internal organ in the male reproductive system
Sertoli cells are the true epithelium of the seminiferous epithelium, critical for the support of germ cell development into spermatozoa. Sertoli cells secrete
Testicle
Distinction between germ cell lineages producing gametes and somatic cells
strict distinction between the "immortal" germ cell lineages producing gametes and "disposable" somatic cells in animals (but not plants), in contrast
Weismann_barrier
Medical condition
sperm cells in the testes do not mature past an early stage, as sensitivity to androgens is required in order for spermatogenesis to complete. Germ cell malignancy
Complete androgen insensitivity syndrome
Complete_androgen_insensitivity_syndrome
Organism that consists of more than one cell
are called Weismannists, a separation between a sterile somatic cell line and a germ cell line evolved. However, Weismannist development is relatively rare
Multicellular_organism
Medical condition
Ovarian germ cell tumors (OGCTs) are heterogeneous tumors that are derived from the primitive germ cells of the embryonic gonad, which accounts for about
Ovarian_germ_cell_tumors
Process by which organisms develop cells
Germ-Soma Differentiation is the process by which organisms develop distinct germline and somatic cells. The development of cell differentiation has been
Germ-Soma_Differentiation
Metaclass used to distinguish between cell forms
cell types. List of distinct cell types in the adult human body List of human cell types derived from the germ layers Stem cell Types of plant cells Zeng
Cell_type
epithelial-stromal tumor) Ovarian germ cell tumor Penile cancer Prostate cancer Renal cell carcinoma Renal pelvis and ureter, transitional cell cancer* Seminoma Serous
List_of_cancer_types
Organism composed of cells of different genotypes
body, fetal-maternal, germ cell, and tumor chimeras. Cytomictical and whole body chimerism in humans are characterised by cells in the body demonstrating
Chimera_(genetics)
Cells found in human testes which help produce sperm
Sertoli cells shortly after birth and stimulates the production of factors derived from Sertoli cells that control the development of the testes and germ cells
Sertoli_cell
Topics referred to by the same term
Look up germ in Wiktionary, the free dictionary. Germ or germs may refer to: Germ (microorganism), an informal word for a pathogen Germ cell, cell that gives
Germ
Sex-specific adaptations
role for cell sex in stem cell-mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency". The Journal of Cell Biology
Sexual_dimorphism
Procreative biological processes of humanity
slightly cooler than body temperature, facilitating sperm production. Male germ cells produced in the testes are able to perform special DNA repair processes
Human_reproduction
Relatively uncommon type of germ cell tumour
Embryonal carcinoma is a relatively uncommon type of nonseminomatous germ cell tumour that occurs in the ovaries and testes. The presenting features may
Embryonal_carcinoma
Medical condition
Rarely, high MSAFP is due to endodermal sinus tumor (EST) or another germ cell tumor containing EST. These tumors can occur in the pregnant woman (often
Elevated_alpha-fetoprotein
Medical condition
thecal cells and fibrocytes. In contrast, the epithelial cells originate from the outer epithelial lining surrounding the gonad while the germ cell tumors
Sex cord–gonadal stromal tumour
Sex_cord–gonadal_stromal_tumour
Reproductive part of a grass seed
The germ of a cereal grain is the part that develops into a plant; it is the seed embryo. Along with bran, germ is often a by-product of the milling that
Cereal_germ
Form of human sexual intercourse
uterus into the fallopian tubes of the woman. If they meet a fertilisable egg cell after or during an ovulation, or if an ovulation occurs hours or days later
Penile–vaginal_intercourse
German evolutionary biologist (1834–1914)
takes place by means of the germ cells—the gametes such as egg cells and sperm cells. Other cells of the body—somatic cells—do not function as agents of
August_Weismann
Liquid mixture produced by the vagina
a mixture of liquid, cells, and bacteria that lubricate and protect the vagina. This mixture is constantly produced by the cells of the vagina and cervix
Vaginal_discharge
Mammalian protein found in Homo sapiens
suppressyn can regulate cell fusion rates and control placental development. Following gastrulation, suppressyn becomes expressed in two germ layers, the endoderm
Suppressyn
Canadian geneticist
developmental genetics. She is known for demonstrating that germ cells engage in cell to cell competition before becoming a gamete, which indicates that
Cassandra_Extavour
Malignant tumor of the testicle
A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a malignant neoplasm and is one
Seminoma
Malignant cancer, usually of the placenta
in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary. increased quantitative chorionic
Choriocarcinoma
Benign, borderline, or malignant neoplasm involving the ovary
epithelial, 3% germ cell, and 2% sex cord-stromal types. Tumor of the ovary vary remarkably as they may arise from any of the 3 cell types of the normal
Ovarian_tumor
Genes and regulatory proteins
genes were identified as regulatory proteins responsible for stem cell and germ cell differentiation. Piwi is an abbreviation of P-element Induced WImpy
Piwi
Condition present at birth regardless of cause
mutations in one of the germ cells that gave rise to the fetus. Male germ cells mutate at a much faster rate than female germ cells, and as the father ages
Birth_defect
Medical condition
include: endometriosis, ovarian cysts, ovarian epithelial cancer, ovarian germ cell tumors, ovarian low malignant potential tumors, and polyendocrine metabolic
Ovarian_disease
Atypical congenital variations of sex characteristics
Immunohistochemical Differences between Gonadal Maturation Delay and Early Germ Cell Neoplasia in Patients with Undervirilization Syndromes". J. Clin. Endocrinol
Intersex
German-American developmental and cell biologist
Isaac Perlmutter Professor of Cell Biology, and the Chair of the Department of Cell Biology. Her research focuses on germ cells and embryogenesis. Lehmann
Ruth_Lehmann
Undifferentiated female germ cell
in large numbers by mitosis early in fetal development from primordial germ cells. In humans they start to develop between weeks 4 and 8 and are present
Oogonium
Medical condition
Endodermal sinus tumor (EST) is a member of the germ cell tumor group of cancers. It is the most common testicular tumor in children under three, and
Endodermal_sinus_tumor
Trait that determines an organism's sexually reproductive function
male, while organisms that produce larger gametes (ova, often called egg cells) are called female. An organism that produces both types of gamete is a
Biological_sex
Australian biologist (born 1959)
McLaren spawned an interest in the regulation of the germ cells during fetal development—cells that later become sperm or oocytes. His group discovered
Peter_Koopman
primordial germ cells around week 7 of embryonic development and exist up until the postnatal period, when they become spermatogonia. Germ cells operate
Gonocyte
Medical technology
therapy (GGT), germ cells (sperm or egg cells) are modified by the introduction of functional genes into their genomes. Modifying a germ cell causes all the
Gene_therapy
Undifferentiated male germ cell
A spermatogonium (plural: spermatogonia) is an undifferentiated male germ cell. Spermatogonia undergo spermatogenesis to form mature spermatozoa in the
Spermatogonium
Medical condition
malignant teratoma. A teratoma is a tumor of germ cell origin, containing tissues from more than one germ cell line, It can be ovarian or testicular in its
Immature_teratoma
Medical condition
A germinoma is a type of germ-cell tumor, which is not differentiated upon examination. It may be benign or malignant. Germinomas are thought to originate
Germinoma
Type of tumor
An extracranial germ cell tumor (EGCT) occurs in the abnormal growth of germ cells in the gonads (testes or ovaries) and the areas other than the brain
Extracranial_germ_cell_tumor
French embryologist
Chironomus which eventually led to the general theory on the autonomy of the germ cell. Also, he conducted comprehensive biological research on the sexual habits
Édouard-Gérard_Balbiani
Specific location in the body containing stem cells
cells whereas germ cells do not contain this receptor- thus alluding to an important role of Leydig cells upstream in mediating renewal. Leydig cells
Stem-cell_niche
Free-living species of nematode
arise from a single primordial germ cell, called the P4 cell, established early in embryogenesis. This primordial cell divides to generate two germline
Caenorhabditis_elegans
Animal organ development
indirect inguinal hernia. Germ cells migrate from near the allantois and colonize the primordial gonads. In the female, the germ cells colonise the cortex and
Development_of_the_gonads
Method of determining sex
fish. All animals have a genome made of DNA, which forms chromosomes during cell division. In humans, most mammals, and some other species, two of the chromosomes
XY_sex-determination_system
Antiquated theory in biology
distinct germ cell line. In preformistic development, the germ line is present since early development. In epigenetic development, the germ line is present
Preformationism
American biologist and corporate director (born 1956)
independently acquiring and amplifying gene families expressed in testicular germ cells. Another study found that the mouse Y chromosome had acquired and massively
David_C._Page
Hormone for the maternal recognition of pregnancy
childbirth or pregnancy loss. Tests can be done to diagnose and monitor germ cell tumors and gestational trophoblastic diseases. Concentrations are commonly
Human_chorionic_gonadotropin
Immature ovum or egg cell
oöcyte, or ovocyte) is a female germ cell involved in sexual reproduction. An oocyte is an immature ovum, an immature egg cell produced in a female fetus in
Oocyte
Japanese biochemist and professor
biochemist and professor well known for developing the cell-free protein expression system based on wheat germ. Born Yaeta Endo (遠藤 弥重太, Endo Yaeta) in 1946 in
Yaeta_Endo
Production of sperm
spermatozoa develop from germ cells in the seminiferous tubules of the testicle. This process starts with the mitotic division of the stem cells located close to
Spermatogenesis
Androgen-producing cell adjacent to the seminiferous tubules of the testicle
Leydig cell tumour is always benign in children, it is malignant in 10% to 15% of adults. It is the most common testicular cancer of non-germ cell origin
Leydig_cell
Medical condition
complication of teratoma that can occur when an immature testicular or ovarian germ cell teratoma is treated by chemotherapy. The masses are benign, but can grow
Growing_teratoma_syndrome
Failure of the testicle(s) to descend into the scrotum
testes are associated with reduced fertility, increased risk of testicular germ-cell tumors, and psychological problems when fully-grown. Undescended testes
Cryptorchidism
Organs involved in reproduction
occurs when certain types of germ cells undergo meiosis to split the normal diploid number of chromosomes (n=46) into haploid cells containing only 23 chromosomes
Human_reproductive_system
and dendrites.[citation needed] List of human cell types derived from the germ layers Human Cell Atlas Cell Ontology List of organs of the human body List
List_of_human_cell_types
Medical condition
A dysgerminoma is a type of germ cell tumor; it usually is malignant and usually occurs in the ovary. A tumor of the identical histology but not occurring
Dysgerminoma
Surgical removal of one or both testicles
orchiectomy, as there is a risk of reduced fertility or infertility. Testicular germ cell tumors (TGCT) accounts for 95% of cases of testicular cancer in young
Orchiectomy
Inherited genetic variation
detectable variation within germ cells (cells that, when fully developed, become sperm and ova). Mutations in these cells are the only mutations that
Germline_mutation
Physical barrier between the blood vessels and the seminiferous tubules of animal testes
Sertoli cells of the seminiferous tubule and isolates the further developed stages of germ cells from the blood. A more correct term is the Sertoli cell barrier
Blood–testis_barrier
Type of pluripotent blastocystic stem cell
derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These germ layers generate each of the more than 220 cell types in the adult human
Embryonic_stem_cell
Congenital disorder of the reproductive system
reproductive system characterized by a progressive loss of primordial germ cells on the developing gonads of an embryo. One type of gonadal dysgenesis
Gonadal_dysgenesis
American football player (1943–1970)
Forest Demon Deacons. He died at age 26 from embryonal cell carcinoma, an aggressive form of germ cell testicular cancer, first diagnosed after it had spread
Brian_Piccolo
Body posture in mammals for sexual receptivity
Sexual reproduction Evolution of sexual reproduction Anisogamy Isogamy Germ cell Meiosis Gametogenesis Spermatogenesis Oogenesis Gamete spermatozoon ovum
Lordosis_behavior
Cell division producing haploid gametes
a special type of cell division of germ cells in sexually-reproducing organisms that produces the gametes, the sperm or egg cells. It involves two rounds
Meiosis
This is a list of cells in humans derived from the three embryonic germ layers – ectoderm, mesoderm, and endoderm. Trichocyte Keratinocyte Gonadotrope
List of human cell types derived from the germ layers
List_of_human_cell_types_derived_from_the_germ_layers
Type of mutation on somatic cell
somatic cell of a multicellular organism with dedicated reproductive cells; that is, any mutation that occurs in a cell other than a gamete, germ cell, or
Somatic_mutation
Founder Cells
formation of a germ cell line, while another study has estimated that, in humans, there are 2 to 3 founder cells responsible for germ line formation.
Founder_cell
Inactivation of copies of X chromosome
leading to: XaM XaP diploid germ cells in meiotic arrest. As the meiosis I only completes with ovulation, human germ cells exist in this stage from the
X-inactivation
State of having three germ layers in embryonic development
the gastrula in which there are three primary germ layers: the ectoderm, mesoderm, and endoderm. Germ cells are set aside in the embryo at the blastula
Triploblasty
Protein-coding gene in the species Homo sapiens
Germ cell-less, spermatogenesis associated 1 is a protein that in humans is encoded by the GMCL1 gene. This gene encodes a nuclear envelope protein that
GMCL1
End of the penis
(1997). "Sensory Innervation of the Human Penis". The Fate of the Male Germ Cell. Advances in Experimental Medicine and Biology. Vol. 424. pp. 265–6. doi:10
Glans_penis
English actor (born 1961)
respectively. On 16 October 2022, Cormac, a musician, died aged 25 from germ cell cancer. As of 2008, Roth was a supporter of the Green Party of England
Tim_Roth
Mammalian protein found in Homo sapiens
expressed in primordial germ cells, spermatogonia, and in primordial oocytes. It is also expressed in the primordial germ cells of females. SCF is expressed
Stem_cell_factor
GERM CELL
GERM CELL
Boy/Male
American, British, English, German
Form of Gerald; Rules by the Spear
Female
Icelandic
Icelandic form of Old Norse Gerðr, GERÃUR means "enclosure, stronghold."
Female
Norse
Old Norse name probably derived from the word garðr, GERÃR means "enclosure, stronghold." In mythology, this is the name of a frost giantess and wife of Freyr.
Girl/Female
Norse
Protection.
Male
German
Contracted form of Old High German Gerhard, GERD means "spear strong."
Girl/Female
Australian, Latin
Gem; A Jewel
Male
Hebrew
(גֵּרָ×) Hebrew name GERA means "a grain." In the bible, this is the name of several characters, including a son of Benjamin.
Female
Scandinavian
Scandinavian form of Old Norse Gerðr, GERD means "enclosure, stronghold."
Male
Spanish
Spanish form of Roman Latin Germanus, GERMÃN means "from Germany."
Female
Icelandic
Icelandic form of Old Norse Gerðr, GERÃA means "enclosure, stronghold."
Girl/Female
American, British, English, French, German
Mighty with a Spear; Rules with Spear; Spear Ruler
Girl/Female
English American
Surname or Lastname
Americanized form of German Gehr.English
Americanized form of German Gehr.English : perhaps a variant of Geary 3.Hungarian : from a reduced form of the personal name Gergely, Latin Gregorius (see Gregory).
Boy/Male
Norse
Guards the gate of Hell.
Boy/Male
Biblical
Pilgrimage, combat, dispute.
Boy/Male
English
Spear hard.
Girl/Female
German
From the Old German name, meaning strong spear.
Girl/Female
British, Dutch, English, French, German
Strength of a Spear; Diminutive of Gertrude
Male
German
Contracted form of Old High German Gerhardt, GERT means "spear strong."
Boy/Male
Teutonic
warrior.
GERM CELL
GERM CELL
Girl/Female
American, Australian, French, Spanish
Star
Boy/Male
Arabic, Muslim
Grace; Favourite
Boy/Male
Tamil
Srivatsan | à®·à¯à®°à¯€à®µà®¤à¯à®¸à®¨
Brilliant, Lord venkateswara
Boy/Male
Hindu
Parmeshwar ka Vardaan
Female
Native American
Native American Hopi name POLIKWAPTIWA means "butterfly sitting on a flower."
Male
Dutch
, father of height.
Boy/Male
Muslim
Glorious, Magnificent, Splendid, Brilliant, Shining
Female
English
Variant spelling of English Zoey, ZOIE means "life."
Boy/Male
Indian, Tamil
Lord Krishna
Girl/Female
Muslim
Beautiful
GERM CELL
GERM CELL
GERM CELL
GERM CELL
GERM CELL
n.
A point, line, or superficies, that limits; as, a line is the term of a superficies, and a superficies is the term of a solid.
n.
A theory of generation in which each germ is supposed to contain the germs of all subsequent generations; -- the opposite of epigenesis.
adv.
Term by term; every term.
n.
A small germ.
n.
That which is to develop a new individual; as, the germ of a fetus, of a plant or flower, and the like; the earliest form under which an organism appears.
n.
A word or expression; specifically, one that has a precisely limited meaning in certain relations and uses, or is peculiar to a science, art, profession, or the like; as, a technical term.
n.
The inner germ layer; endoderm. See Nucleolus.
n.
Germ history of cells, and of the tissues composed of cells.
n.
That from which anything springs; origin; first principle; as, the germ of civil liberty.
n.
A simple, minute organism; a primary cell, germ, or plastid.
n.
The time for which anything lasts; any limited time; as, a term of five years; the term of life.
n.
See Germ.
n.
A piece of carved work placed under each end of the taffrail.
v. t.
To daub, as the hands or clothing, with gorm; to daub with anything sticky.
n.
To apply a term to; to name; to call; to denominate.
n.
Anything of small size, or expressed within brief limits, which is regarded as a gem on account of its beauty or value, as a small picture, a verse of poetry, a witty or wise saying.
n.
A bud; a germ of a plant.
v. i.
To germinate.
n.
The limitation of an estate; or rather, the whole time for which an estate is granted, as for the term of a life or lives, or for a term of years.