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HYPERVARIABLE REGION

  • Hypervariable region
  • Highly polymorphic DNA region

    A hypervariable region (HVR) is a location within a sequence where polymorphisms frequently occur. It is used in two contexts: In the case of nucleic acids

    Hypervariable region

    Hypervariable_region

  • Complementarity-determining region
  • Part of the variable chains in immunoglobulins and T cell receptors

    H3-rules are empirical rules to build models of CDR3. Framework region Hypervariable region Osajima T, Suzuki M, Neya S, Hoshino T (September 2014). "Computational

    Complementarity-determining region

    Complementarity-determining region

    Complementarity-determining_region

  • Haplogroup K1a1b1a (mtDNA)
  • Human mitochondrial DNA haplogroup

    recognized in hypervariable-only samples by the following essential mutations: Hypervariable region 1: 16224C, 16234T, 16311C, 16519C Hypervariable region 2: 073G

    Haplogroup K1a1b1a (mtDNA)

    Haplogroup_K1a1b1a_(mtDNA)

  • 16S ribosomal RNA
  • RNA component

    sections of the 16S sequence across different taxa. Although no hypervariable region can accurately classify all bacteria from domain to species, some

    16S ribosomal RNA

    16S ribosomal RNA

    16S_ribosomal_RNA

  • Framework region
  • regions and three of which are hypervariable regions. The framework region makes up about 85% of the variable region. Located on the tips of the Y-shaped

    Framework region

    Framework region

    Framework_region

  • Hypervariable
  • Topics referred to by the same term

    loci Hypervariable locus, a locus with many alleles; especially those whose variation is due to variable numbers of tandem repeats Hypervariable region (HVR)

    Hypervariable

    Hypervariable

  • Hazara region
  • Region in northern Pakistan

    mtDNA) for determination of maternal affinities, diversity in the hypervariable region and availability of haplogroups, in different tribes. "Races and

    Hazara region

    Hazara_region

  • MtDNA control region
  • Non-coding region of the mitochondrial DNA

    found that mutations in the control region of mtDNA have been linked with aging as well. D-loop Hypervariable region McBride, Heidi M.; Neuspiel, Margaret;

    MtDNA control region

    MtDNA control region

    MtDNA_control_region

  • Hepatitis C virus
  • Species of virus

    interactions hepatitis C has with the immune system. A hypervariable region, the hypervariable region 1 (HVR1) can be found on the E2 glycoprotein. HVR1 is

    Hepatitis C virus

    Hepatitis C virus

    Hepatitis_C_virus

  • M protein (Streptococcus)
  • Protein family

    the hypervariable region, are extremely variable in sequence and account for the high variation in antigenicity of Streptococcus strains. This region binds

    M protein (Streptococcus)

    M_protein_(Streptococcus)

  • Mummy Juanita
  • Mummified Inca girl sacrifice

    Andes. Researchers also identified a unique genetic sequence within Hypervariable Region 2 (HV2) that was not present in the mitochondrial DNA databases available

    Mummy Juanita

    Mummy_Juanita

  • HVR
  • Topics referred to by the same term

    British Columbia, Canada Hotham Valley Railway, in Western Australia Hypervariable region, a location within nuclear or mitochondrial DNA Hypoxic ventilatory

    HVR

    HVR

  • Mitochondrial Eve
  • Matrilineal most recent common ancestor of all living humans

    1999). "Substitution rate variation among sites in mitochondrial hypervariable region I of humans and chimpanzees". Molecular Biology and Evolution. 16

    Mitochondrial Eve

    Mitochondrial Eve

    Mitochondrial_Eve

  • RHEB
  • Protein-coding gene in the species Homo sapiens

    up the GTPase domain, and the remaining amino acids are part of a hypervariable region ending at the C-terminus in a CAAX motif (C – cysteine, A – aliphatic

    RHEB

    RHEB

    RHEB

  • Index of genetics articles
  • zone Hybridoma Hydrogen bond Hydroxyapatite Hypermorph Hyperploid Hypervariable region Hypomorph Hypoploid Hypostatic gene Ichthyosis Identical twin Identity

    Index of genetics articles

    Index_of_genetics_articles

  • Basra
  • Port city in southern Iraq

    Muften; Al-Badran, Adnan Issa (11 April 2020). "Mitochondrial DNA (hypervariable region I) diversity in Basrah population - Iraq". Genomics. 112 (5): 3560–3564

    Basra

    Basra

    Basra

  • FamilyTreeDNA
  • Commercial genetic testing company

    [citation needed] FamilyTreeDNA's first mtDNA tests were for HVR1 (hypervariable region 1) of the mtDNA.[citation needed] Eventually, they added a Plus test

    FamilyTreeDNA

    FamilyTreeDNA

  • Moken language
  • Austronesian language spoken in southern Thailand and in western Burma

    (2009). "Origins of the Moken Sea Gypsies Inferred from Mitochondrial Hypervariable Region and Whole Genome Sequences". Journal of Human Genetics. 54 (2): 86–93

    Moken language

    Moken_language

  • Neanderthal genetics
  • Genetic study of ancient Neanderthal DNA

    Krainitzki, H.; Pääbo, S. (1999). "DNA sequence of the mitochondrial hypervariable region II from the Neandertal type specimen". Proceedings of the National

    Neanderthal genetics

    Neanderthal_genetics

  • Hypogammaglobulinemia
  • Human disease

    (1998). "Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic

    Hypogammaglobulinemia

    Hypogammaglobulinemia

  • Molecular mimicry
  • Proposed cause of autoimmunity

    example, the QKRAA sequence is an amino acid motif in the third hypervariable region of HLA-DRB1*04:01. This motif is also expressed on numerous proteins

    Molecular mimicry

    Molecular_mimicry

  • KRAS
  • Protein-coding gene in humans

    Hagmann J (September 2000). "Structure and function of the C-terminal hypervariable region of K-Ras4B in plasma membrane targetting and transformation". Oncogene

    KRAS

    KRAS

    KRAS

  • Robert Purcell (virologist)
  • American virologist

    virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. Proceedings of the National Academy

    Robert Purcell (virologist)

    Robert Purcell (virologist)

    Robert_Purcell_(virologist)

  • Syncytin-1
  • Protein found in humans

    contains at its C-terminus a 21 residue hypervariable region between human, mouse, and hamster receptors. This region was shown to confer specificity to receptor

    Syncytin-1

    Syncytin-1

    Syncytin-1

  • RALA
  • Protein-coding gene in the species Homo sapiens

    100% match in their effector-binding region. The two isoforms mainly differ in the C-terminal hypervariable region, which contains multiple sites for post-translational

    RALA

    RALA

    RALA

  • Protein–carbohydrate interaction
  • Intermolecular and intramolecular interactions between protein and carbohydrate moieties

    have the similar structure except the hypervariable region which is called the antigen binding site. This region is constituted by the combination of various

    Protein–carbohydrate interaction

    Protein–carbohydrate_interaction

  • Genetic studies of Jews
  • DNA analysis of Jewish populations

    research by M. Thomas et al. that was based on studying only the hypervariable region 1 (HVS-I) seemed to show that about 26%-27% of Moroccan Jews descend

    Genetic studies of Jews

    Genetic_studies_of_Jews

  • Etruscan origins
  • Theories on the ancient Italian civilization

    Etruscans were a native population. The study extracted and typed the hypervariable region of mitochondrial DNA of 14 individuals buried in two Etruscan necropoleis

    Etruscan origins

    Etruscan origins

    Etruscan_origins

  • Volvereviria
  • Realm of viruses

    prophage contains a hypervariable region that prevents superinfection of the same cell with other microviruses that have similar hypervariable regions. Microviruses

    Volvereviria

    Volvereviria

  • Hepatitis D
  • Human infectious disease

    position : the hypervariable region evolved faster (4.55×10−3 substitutions per site per year) than the hepatitis delta antigen coding region (2.60×10−3 substitutions

    Hepatitis D

    Hepatitis_D

  • Human mitochondrial molecular clock
  • Archaological dating based on mutation rate

    1999), "Substitution rate variation among sites in mitochondrial hypervariable region I of humans and chimpanzees", Mol. Biol. Evol., 16 (10): 1357–68

    Human mitochondrial molecular clock

    Human_mitochondrial_molecular_clock

  • Genealogical DNA test
  • DNA-based genetic test

    mitochondrial Haplogroup determination test based on mutations in Hypervariable Region 1 and 2 may establish whether a person's direct female line belongs

    Genealogical DNA test

    Genealogical_DNA_test

  • Coronavirus 3′ UTR
  • structure probing experiments. Downstream of this pseudoknot lies the hypervariable region (HVR), which is supported by many covarying base pairs in alphacoronaviruses

    Coronavirus 3′ UTR

    Coronavirus_3′_UTR

  • TNNT3
  • Protein-coding gene in the species Homo sapiens

    PMC 1794682. PMID 17260966. Amarasinghe C, Jin JP (Jun 2015). "N-Terminal Hypervariable Region of Muscle Type Isoforms of Troponin T Differentially Modulates the

    TNNT3

    TNNT3

    TNNT3

  • Antibody
  • Protein(s) forming a major part of an organism's immune system

    as the FV region. It is the subregion of Fab that binds to an antigen. More specifically, each variable domain contains three hypervariable regions –

    Antibody

    Antibody

    Antibody

  • Nucleolus organizer region
  • Baicharoen S, Hirai Y, Srikulnath K, Kongprom U, Hirai H (2016). "Hypervariability of Nucleolus Organizer Regions in Bengal Slow Lorises, Nycticebus bengalensis

    Nucleolus organizer region

    Nucleolus organizer region

    Nucleolus_organizer_region

  • Bile salt-dependent lipase
  • Mammalian protein found in Homo sapiens

    lipase-like (CELL) gene is ubiquitously expressed and contains a hypervariable region". Genomics. 17 (2): 416–22. doi:10.1006/geno.1993.1341. PMID 7691717

    Bile salt-dependent lipase

    Bile salt-dependent lipase

    Bile_salt-dependent_lipase

  • Peltigera islandica
  • Species of lichen

    Peltigera by a distinct molecular characteristic: the absence of the hypervariable region in the ITS1 (ITS1-HR), which is present in all other currently recognized

    Peltigera islandica

    Peltigera_islandica

  • Genetic saturation
  • Observation in evolutionary biology

    saturation occurs most rapidly on fast-evolving sequences, such as the hypervariable region of mitochondrial DNA, or in short tandem repeats such as on the Y-chromosome

    Genetic saturation

    Genetic_saturation

  • RAB11B
  • Protein-coding gene in the species Homo sapiens

    different from Rab11a. High sequence diversity in the C-terminal hypervariable region is responsible for variable membrane targeting between these proteins

    RAB11B

    RAB11B

    RAB11B

  • Algae DNA barcoding
  • Technique used for species identification and phylogenetic studies

    already been developed, mainly targeting the 18S rRNA. Using the V4 hypervariable region of the ribosomal small subunit DNA (SSU rDNA), DNA-based identification

    Algae DNA barcoding

    Algae DNA barcoding

    Algae_DNA_barcoding

  • RALB
  • Protein-coding gene in the species Homo sapiens

    100% match in their effector-binding region. The two isoforms mainly differ in the C-terminal hypervariable region, which contains multiple sites for post-translational

    RALB

    RALB

    RALB

  • Riccardo Cortese
  • Italian scientist and entrepreneur

    (1998). "Towards a solution for hepatitis C virus hypervariability: mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large

    Riccardo Cortese

    Riccardo Cortese

    Riccardo_Cortese

  • Okladnikov Cave
  • Cave and archaeological site in Russia

    individual, dubbed Okladnikov 2. The mtDNA sequences of the HVR I (hypervariable region I) from Okladnikov 2 confirmed that the individual was Neanderthal

    Okladnikov Cave

    Okladnikov Cave

    Okladnikov_Cave

  • TNNT1
  • Protein-coding gene in the species Homo sapiens

    PMID 26296490. S2CID 41713544. Amarasinghe C, Jin JP (Jun 2015). "N-Terminal Hypervariable Region of Muscle Type Isoforms of Troponin T Differentially Modulates the

    TNNT1

    TNNT1

    TNNT1

  • Sorenson Molecular Genealogy Foundation
  • DNA and genealogical research institution

    of the D-loop of mtDNA: HVR1, HVR2 and HVR3 which is called the Hypervariable region. Mutations in these areas of mtDNA are extremely rare and have likely

    Sorenson Molecular Genealogy Foundation

    Sorenson_Molecular_Genealogy_Foundation

  • Avibirnavirus
  • Genus of viruses

    mutation rate and inter-strain homologous recombination within a hypervariable region that is located in the vp2 gene. At approximately 3,200 bp in length

    Avibirnavirus

    Avibirnavirus

    Avibirnavirus

  • Peltigera hydrophila
  • Species of lichen

    sister species P. aubertii, by a unique internal transcribed spacer 1 hypervariable region (ITS1-HR). The close genetic relationship with P. aubertii was corroborated

    Peltigera hydrophila

    Peltigera hydrophila

    Peltigera_hydrophila

  • Novilara necropolis
  • Archaeological site in Marche, Italy

    multidimensional scaling (MDS) analysis comparing the mtDNA of the first hypervariable region in the Novilaran population to samples of Italians who lived in 1833

    Novilara necropolis

    Novilara_necropolis

  • Outline of immunology
  • Overview of and topical guide to immunology

    Regions Paratope Complementarity-determining region (CDRs) Hypervariable region Framework region Fab Region Fc Region Polyclonal B cell response Cell-mediated

    Outline of immunology

    Outline_of_immunology

  • Antigen-antibody interaction
  • Immune response chemical interaction

    that recognizes and binds to an antigen. The rest of the V region between the hypervariable regions are called framework regions. Each V domain has four

    Antigen-antibody interaction

    Antigen-antibody_interaction

  • DNA barcoding
  • Method of species identification using a short section of DNA

    different organismal groups using barcoding. The most commonly used barcode region for animals and some protists is a portion of the cytochrome c oxidase I

    DNA barcoding

    DNA barcoding

    DNA_barcoding

  • Southern Cone
  • Southern subregion of South America

    Jorquera, H; Cifuentes, L; Armanet, L (30 June 2002). "Frequency of the hypervariable DNA loci D18S849, D3S1744, D12S1090 and D1S80 in a mixed ancestry population

    Southern Cone

    Southern Cone

    Southern_Cone

  • Subclade
  • Subgroup of a haplogroup in genetics

    single-nucleotide polymorphism (SNP) markers in the hypervariable regions and the coding region of mitochondrial DNA. They are named with the capital

    Subclade

    Subclade

  • Minisatellite
  • Repeating segment of DNA (10-60 base pairs)

    (G)) and pyrimidines (cytosine (C) and thymine (T)).[citation needed] Hypervariable minisatellites have core units 9–64 bp long and are found mainly at

    Minisatellite

    Minisatellite

  • Phalaenopsis inscriptiosinensis
  • Species of epiphytic orchid

    (pp. 1-24). Kishor, R., & Sharma, G. J. (2018). The use of the hypervariable P8 region of trn L (UAA) intron for identification of orchid species: Evidence

    Phalaenopsis inscriptiosinensis

    Phalaenopsis inscriptiosinensis

    Phalaenopsis_inscriptiosinensis

  • Multicopy single-stranded DNA
  • many other bacteria revealed conserved and hypervariable domains reminiscent of conserved and hypervariable sequences found in allorecognition molecules

    Multicopy single-stranded DNA

    Multicopy single-stranded DNA

    Multicopy_single-stranded_DNA

  • Somalis
  • Cushitic ethnic group native to the Horn of Africa

    generated so far is limited to the analysis of the first hypervariable segment (HVS-1) of the control region (CR). Therefore, this study aimed on the investigation

    Somalis

    Somalis

    Somalis

  • Rock partridge
  • Species of bird

    are only weakly differentiated with regard to mtDNA D-loop and hypervariable control region sequences and microsatellite genotyping. As they nonetheless

    Rock partridge

    Rock partridge

    Rock_partridge

  • Immunoglobulin heavy constant alpha 1
  • Gene in the species Homo sapiens

    the beta-sandwich is connected by a series of loops, which define a hypervariable loop system, that may have a role in determining the specificity of

    Immunoglobulin heavy constant alpha 1

    Immunoglobulin heavy constant alpha 1

    Immunoglobulin_heavy_constant_alpha_1

  • Campylobacter
  • Genus of gram-negative bacteria

    A characteristic of most Campylobacter genomes is the presence of hypervariable regions, which can differ greatly between different strains. Studies

    Campylobacter

    Campylobacter

    Campylobacter

  • Vedda
  • Indigenous people in Sri Lanka

    Eurasian haplogroups." One phylogenetic study on mitochondrial DNA hypervariable segments HVI and part of HVII showed the Vedda to be "genetically distinct

    Vedda

    Vedda

    Vedda

  • Azerbaijanis
  • Turkic ethnic group

    contribution to Azerbaijan. A 2001 study which looked into the first hypervariable segment of the MtDNA suggested that "genetic relationships among Caucasus

    Azerbaijanis

    Azerbaijanis

    Azerbaijanis

  • Alec Jeffreys
  • British geneticist (born 1950)

    PMC 3909909. PMID 24490906. Jeffreys, A.; Wilson, V.; Thein, S. (1985). "Hypervariable 'minisatellite' regions in human DNA". Nature. 314 (6006): 67–73. Bibcode:1985Natur

    Alec Jeffreys

    Alec Jeffreys

    Alec_Jeffreys

  • Swee Lay Thein
  • Malaysian haematologist

    Sciences 2026 – Warren Alpert Foundation Prize Thein, Swee Lay (1985). "Hypervariable 'minisatellite'regions in human DNA". Nature. 314 (6006): 67–73. Bibcode:1985Natur

    Swee Lay Thein

    Swee Lay Thein

    Swee_Lay_Thein

  • T-cell receptor
  • Protein complex on the surface of T cells that recognizes antigens

    β-chain each have three hypervariable or complementarity-determining regions (CDRs). There is also an additional area of hypervariability on the β-chain (HV4)

    T-cell receptor

    T-cell receptor

    T-cell_receptor

  • Haplogroup HV
  • Human mitochondrial DNA grouping indicating common ancestry

    HV10 H Defining mutation C/T at location 16298 in segment I one of the hypervariable segment is labeled as HV0 as of 2012. The percentage of people that

    Haplogroup HV

    Haplogroup_HV

  • Microsatellite
  • Repeating sequences of 2–13 base pairs of DNA

    PMC 5785450. PMID 28949426. Jeffreys AJ; Wilson V; Thein SL (1985). "Hypervariable 'minisatellite' regions in human DNA". Nature. 314 (6006): 67–73. Bibcode:1985Natur

    Microsatellite

    Microsatellite

  • Biosensor
  • Probe which tests for biological molecules

    AgBPs are constituted by a set of hypervariable (or randomized) residue positions, located in a unique sub-region of the protein, and supported by a

    Biosensor

    Biosensor

  • Cannabis
  • Genus of flowering plants

    Robertson J (January 2003). "Short tandem repeat (STR) DNA markers are hypervariable and informative in Cannabis sativa: implications for forensic investigations"

    Cannabis

    Cannabis

    Cannabis

  • Catherine Eddowes
  • Whitechapel murder victim (1842–1888)

    alleged DNA match was based on one of seven small segments taken from the hypervariable regions within the DNA. The segment contained a sequence variation described

    Catherine Eddowes

    Catherine Eddowes

    Catherine_Eddowes

  • Somatic hypermutation
  • Cellular mechanism in B cells

    mutations occur mostly at "hotspots" in the DNA, which are concentrated in hypervariable regions. These regions correspond to the complementarity-determining

    Somatic hypermutation

    Somatic_hypermutation

  • CDR
  • Topics referred to by the same term

    expectations and their reality. Complementarity-determining region, one of six hypervariable loops which determine the antigen specificity of a given antibody

    CDR

    CDR

  • Linear Pottery culture
  • Archaeological horizon of Neolithic Europe

    additional sample each from Austria and Hungary. Although the full hypervariable segment I (HVSI) sequences were not published, the study identified

    Linear Pottery culture

    Linear Pottery culture

    Linear_Pottery_culture

  • Monoclonal antibody therapy
  • Form of immunotherapy

    crystallizable region) part of the molecule. The Fab fragments contain the variable domains, which consist of three antibody hypervariable amino acid domains

    Monoclonal antibody therapy

    Monoclonal antibody therapy

    Monoclonal_antibody_therapy

  • Humanized antibody
  • Antibodies from non-human species made nearly identical with human ones

    dubbed "Campath-1" was developed to bind CD52 using a mouse system. The hypervariable loops of Campath-1 (that contain its CDRs and thereby impart its ability

    Humanized antibody

    Humanized_antibody

  • Prenylation
  • Addition of hydrophobic moieties to proteins or other biomolecules

    of Rab proteins varies in length and sequence and is referred to as hypervariable. Thus Rab proteins do not have a consensus sequence, such as the CAAX

    Prenylation

    Prenylation

    Prenylation

  • Molecular anthropology
  • Field of anthropology

    the boundary has changed. Such recombinant changes in the non-recombinant region of Y are extremely rare.[citation needed] Mitochondrial DNA became an area

    Molecular anthropology

    Molecular_anthropology

  • Indo-Aryan migrations
  • Migrations of Indo-Aryans into the Indian subcontinent

    S.; Saha, A.; Rai, E.; Bhat, A.; Bamezai, R. (2005), "Human mtDNA hypervariable regions, HVR I and II, hint at deep common maternal founder and subsequent

    Indo-Aryan migrations

    Indo-Aryan_migrations

  • RASEF
  • Protein-coding gene in the species Homo sapiens

    Gorvel JP, Stelzer E, Simons K, Gruenberg J, Zerial M (October 1991). "Hypervariable C-terminal domain of rab proteins acts as a targeting signal". Nature

    RASEF

    RASEF

    RASEF

  • Demographics of the Southern Cone
  • Spanish). 130 (8). doi:10.4067/S0034-98872002000800006. "Frequency of the hypervariable DNA loci D18S849, D3S1744, D12S1090 and D1S80 in a mixed ancestry population

    Demographics of the Southern Cone

    Demographics of the Southern Cone

    Demographics_of_the_Southern_Cone

  • Adeno-associated virus
  • Species of virus

    serotypes described, the 11th in 2004. AAV capsid proteins contain 12 hypervariable surface regions, with most variability occurring in the threefold proximal

    Adeno-associated virus

    Adeno-associated virus

    Adeno-associated_virus

  • Signal transduction
  • Cascade of intracellular and molecular events for transmission/amplification of signals

    crystallizable region). An analysis of multiple V region sequences by Wu and Kabat identified locations within the V region that were hypervariable and which

    Signal transduction

    Signal transduction

    Signal_transduction

  • Cyclotide
  • Disulfide-rich ring peptides found in plants

    cyclotide architecture comprises a conserved core onto which a series of hypervariable loops is displayed suggest that cyclotides may be able to target many

    Cyclotide

    Cyclotide

    Cyclotide

  • DNA profiling
  • Technique used to identify individuals via DNA characteristics

    nucleotide substitutions in the first and second hypervariable segments of the human mtDNA control region". International Journal of Legal Medicine. 109

    DNA profiling

    DNA profiling

    DNA_profiling

  • Streptococcus dysgalactiae
  • Species of bacterium

    dysgalactiae subspecies equisimilis of human origin, and its hypervariability in the 5'-terminal region forms the basis for categorization into separate emm-types

    Streptococcus dysgalactiae

    Streptococcus dysgalactiae

    Streptococcus_dysgalactiae

  • Adaptive immune system
  • Subsystem of the immune system

    PMID 19840170. Dong Y, Taylor HE, Dimopoulos G (July 2006). "AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate

    Adaptive immune system

    Adaptive immune system

    Adaptive_immune_system

  • Mitochondrial DNA
  • DNA located in mitochondria

    is usually accomplished on human mitochondrial DNA by sequencing the hypervariable control regions (HVR1 or HVR2), and sometimes the complete molecule

    Mitochondrial DNA

    Mitochondrial DNA

    Mitochondrial_DNA

  • Lake St. Lucia
  • Lake system in KwaZulu-Natal, South Africa

    is a key factor underlying the system's distinctive environmental hypervariability. Lake St Lucia comprises three distinct sub-basins, each with differing

    Lake St. Lucia

    Lake St. Lucia

    Lake_St._Lucia

  • Flora of Madagascar
  • Plants endemic to Madagascar

    ISSN 0024-4074. Dewar, R.E.; Richard, A.F. (2007). "Evolution in the hypervariable environment of Madagascar". Proceedings of the National Academy of Sciences

    Flora of Madagascar

    Flora of Madagascar

    Flora_of_Madagascar

  • Neolithic Europe
  • Era of pre-history prior to copper & bronze ages in each region

    is Chikhi. In his 1998 study, utilising polymorphic loci from seven hypervariable autosomal DNA loci, an autocorrelation analysis produced a clinal pattern

    Neolithic Europe

    Neolithic Europe

    Neolithic_Europe

  • Phu Quoc Ridgeback
  • Vietnamese breed of dog

    DIVERSITY OF PHU QUOC RIDGEBACK DOGS BASED ON MITOCHONDRIAL DNA HYPERVARIABLE-1 REGION". Journal of Biotechnology. 14 (1A): 245–253. Quan, Q.D.; Nguyen

    Phu Quoc Ridgeback

    Phu Quoc Ridgeback

    Phu_Quoc_Ridgeback

  • Antigen processing
  • Immunological process

    chain. Each chain has a variable (V) region and a constant (C) region. The V regions each contain 3 hypervariable regions that make up the antigen-binding

    Antigen processing

    Antigen_processing

  • Diversity-generating retroelement
  • error-prone reverse transcriptase is responsible for generating these hypervariable regions in target proteins (Mutagenic retrohoming). In mutagenic retrohoming

    Diversity-generating retroelement

    Diversity-generating_retroelement

  • Potyvirus
  • Genus of positive-strand RNA viruses in the family Potyviridae

    as ITPase or HAM1). Such anomalies are often situated in the hypervariable P1-HC-Pro region. Most potyviruses are transmitted by aphids as they probe plant

    Potyvirus

    Potyvirus

    Potyvirus

  • Repeated sequence (DNA)
  • Patterns of nucleic acids that occur in multiple copies throughout the genome

    "Meiotic recombination hotspots: shaping the genome and insights into hypervariable minisatellite DNA change". Current Topics in Developmental Biology.

    Repeated sequence (DNA)

    Repeated_sequence_(DNA)

  • DSCAM
  • Protein-coding gene in the species Homo sapiens

    PMID 15780842. Dong Y, Taylor HE, Dimopoulos G (July 2006). "AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate

    DSCAM

    DSCAM

    DSCAM

  • Erika Hagelberg
  • British biologist and professor

    Nucleotide Substitutions in the First and Second Hypervariable Segments of the Human mtDNA Control Region', International Journal of Legal Medicine 109 (1996)

    Erika Hagelberg

    Erika Hagelberg

    Erika_Hagelberg

  • ORF8
  • Gene that encodes a viral accessory protein

    been described as "hypervariable" and a recombination hotspot. It has been suggested that RNA secondary structures in the region are associated with

    ORF8

    ORF8

    ORF8

  • Rab geranylgeranyltransferase
  • Class of enzyme complexes

    of Rab proteins varies in length and sequence and is referred to as hypervariable. Thus Rab proteins do not have a consensus sequence, such as the CAAX

    Rab geranylgeranyltransferase

    Rab geranylgeranyltransferase

    Rab_geranylgeranyltransferase

AI & ChatGPT searchs for online references containing HYPERVARIABLE REGION

HYPERVARIABLE REGION

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HYPERVARIABLE REGION

  • Mansell
  • Surname or Lastname

    English (chiefly West Midlands)

    Mansell

    English (chiefly West Midlands) : (of Norman origin): habitational or regional name from Old French mansel ‘inhabitant of Le Mans or the surrounding area of Maine’. The place was originally named in Latin (ad) Ceromannos, from the name of the Gaulish tribe living there, the Ceromanni. The name was reduced to Celmans and then became Le Mans as a result of the mistaken identification of the first syllable with the Old French demonstrative adjective.English (chiefly West Midlands) : status name for a particular type of feudal tenant, Anglo-Norman French mansel, one who occupied a manse (Late Latin mansa ‘dwelling’), a measure of land sufficient to support one family.English (chiefly West Midlands) : some early examples, such as Thomas filius Manselli (Northumbria 1256), point to derivation from a personal name, perhaps the Germanic derivative of Mann 2 Latinized as Manzellinus.

    Mansell

  • Lister
  • Surname or Lastname

    English

    Lister

    English : occupational name for a dyer, Middle English litster, an agent derivative (originally feminine; compare Baxter) of lit(t)e(n) ‘to dye’ (Old Norse lita). This term was used principally in East Anglia and northern and eastern England (areas of Scandinavian settlement), and to this day the surname is found principally in these regions, especially in Yorkshire.Scottish : Anglicized form of Gaelic Mac an Fhleisdeir ‘son of the arrow maker’.

    Lister

  • Manley
  • Surname or Lastname

    English

    Manley

    English : habitational name from places in Devon and Cheshire, named in Old English as ‘common wood or clearing’, from (ge)mǣne ‘common’, ‘shared’ + lēah ‘woodland clearing’. The surname is still chiefly found in the regions around these villages.English : nickname from Middle English mannly ‘manly’, ‘virile’, ‘brave’ (Old English mannlīc, originally ‘man-like’).Irish (County Cork) : Anglicized form of Ó Máinle (and often pronounced Mauly), of unexplained origin. Compare Malley.Irish (Connacht and Donegal) : shortened Anglicized form of Gaelic Ó Maonghaile ‘descendant of Maonghal’, a personal name derived from words meaning ‘wealth’ and ‘valor’.

    Manley

  • Janis
  • Surname or Lastname

    English

    Janis

    English : perhaps a variant spelling of Janice.French : unexplained.Latvian : from the first name Jānis, Latvian form of John.A Janis from the Champagne region of France is documented in 1704 in Trois Rivières, Quebec, with the secondary surname Sicard.

    Janis

  • Hughston
  • Surname or Lastname

    English

    Hughston

    English : of uncertain origin; it could be a Scottish habitational name from Hughston in the Highland region but is more likely a variant spelling of Houston.

    Hughston

  • Jeffrey
  • Surname or Lastname

    English

    Jeffrey

    English : from a Norman personal name that appears in Middle English as Geffrey and in Old French as Je(u)froi. Some authorities regard this as no more than a palatalized form of Godfrey, but early forms such as Galfridus and Gaufridus point to a first element from Germanic gala ‘to sing’ or gawi ‘region’, ‘territory’. It is possible that several originally distinct names have fallen together in the same form.

    Jeffrey

  • Jourdan
  • Surname or Lastname

    English and French

    Jourdan

    English and French : variant of Jordan.A Jourdain from the Saintonge region of France is recorded in Quebec City in 1676. Another, from the Savoie, is documented in 1688 in Lachine, Quebec, with the secondary surname Lafrizade. A third, from Provence, is documented in Champlain, Quebec, in 1688; and another, also called Labrosse, in Montreal in 1696. Other secondary surnames include Bellerose, Lafrance, and Saint-Louis.

    Jourdan

  • Lorraine
  • Surname or Lastname

    English and French

    Lorraine

    English and French : regional name from the border region of Lorraine in northeastern France, so called from the Germanic tribal name Lotharingi ‘people of Lothar’ (a personal name composed of the elements hlod ‘famous’, ‘renowned’ + hari, heri ‘army’).

    Lorraine

  • Jean
  • Surname or Lastname

    French

    Jean

    French : from the personal name Jean, French form of John.English : variant of Jayne.A Vivien Jean, recorded in Canada in 1681, was also known as Vien; some descendants adopted that surname and are now called Vien or Viens. Another Jean, from the Saintonge region of France, is documented in Quebec City in 1655 with the secondary surname Denis. Other secondary surnames associated with this name include Laforest, Godon, Tourangeau, Vincent, and Pierrejean.

    Jean

  • Manton
  • Surname or Lastname

    English

    Manton

    English : habitational name from any of the various places so called, for example in Leicestershire, Lincolnshire, Nottinghamshire, and Wiltshire. For the most part the first element is either Old English (ge)mǣne ‘common’, ‘shared’ (see Manley, Manship), or the Old English byname Mann(a) (see Mann). However, in the case of Manton in Lincolnshire the early forms show clearly that it was Old English m(e)alm ‘sand’, ‘chalk’, with reference to the poor soil of the region. The second element is in each case Old English tūn ‘enclosure’, ‘settlement’.Irish (Cork) : Anglicized form of Gaelic Ó Manntáin ‘descendant of Manntán’, a personal name derived from a diminutive of manntach ‘toothless’.

    Manton

  • Mason
  • Surname or Lastname

    English and Scottish

    Mason

    English and Scottish : occupational name for a stonemason, Middle English, Old French mas(s)on. Compare Machen. Stonemasonry was a hugely important craft in the Middle Ages.Italian (Veneto) : from a short form of Masone.French : from a regional variant of maison ‘house’.George Mason (1725–92), the American colonial statesman who framed the VA Bill of Rights and Constitution, which was used as a model by Thomas Jefferson when drafting the Declaration of Independence, was a VA planter, fourth in descent from George Mason (?1629–?86), a royalist soldier of the English Civil War who had received land grants in VA. As well as being prominent in the affairs of VA, the family also produced the first governor of MI.

    Mason

  • Litwin
  • Surname or Lastname

    Polish, German, and Jewish (eastern Ashkenazic)

    Litwin

    Polish, German, and Jewish (eastern Ashkenazic) : from Polish litwin, an ethnic name for someone from Lithuania (Polish Litwa, Lithuanian Lietuva, a word of uncertain etymology, perhaps a derivative of the river name Leità). In the 14th century Lithuania was an independent grand duchy which extended from the Baltic to the shores of the Black Sea. It was united with Poland in 1569, and was absorbed into the Russian empire in 1795. The region referred to as Lite in Ashkenazic culture encompassed not only Lithuania but also Latvia, Estonia, Belarus, parts of northern Ukraine, and parts of northeastern Poland.English : from an Old English personal name, Lēohtwine, composed of the elements lēoht ‘light’, ‘bright’ + wine ‘friend’.

    Litwin

  • Julien
  • Surname or Lastname

    French

    Julien

    French : from the personal name, French form of Julian.English : variant spelling of Julian.From the Dauphiné region of France, a Julien, also called Vantabon, is documented in Quebec City in 1654. A Julien or Jullien, from Poitou, France, is recorded in Quebec City in 1665. Other secondary surnames associated with this name include LeDragon and Saint-Julien.

    Julien

  • Lucas
  • Surname or Lastname

    English, French, Spanish, Portuguese, Dutch, etc.

    Lucas

    English, French, Spanish, Portuguese, Dutch, etc. : from the Latin personal name Lucas (Greek Loukas) ‘man from Lucania’. Lucania is a region of southern Italy thought to have been named in ancient times with a word meaning ‘bright’ or ‘shining’. Compare Lucio. The Christian name owed its enormous popularity throughout Europe in the Middle Ages to St. Luke the Evangelist, hence the development of this surname and many vernacular derivatives in most of the languages of Europe. Compare Luke. This is also found as an Americanized form of Greek Loukas.Scottish : reduced Anglicized form of Gaelic Mac Lùcais (see McLucas).As a French name Lucas has been recorded in Canada since 1653, taken to Trois Rivières, Quebec, by one Lucas-Lépine from Normandy.

    Lucas

  • Holland
  • Surname or Lastname

    Irish

    Holland

    Irish : reduced Anglicized form of Gaelic Ó hÓileáin, a variant of Ó hAoláin, from a form of Faolán (with loss of the initial F-), a personal name representing a diminutive of faol ‘wolf’. Compare Whelan.English and Scottish : habitational name from Holland, a division of Lincolnshire, or any of the eight villages in various parts of England so called, from Old English hōh ‘ridge’ + land ‘land’. The Scottish name may also be from places called Holland in Orkney, Houlland in Shetland, Hollandbush in Stirlingshire, and Holland-Hirst in the parish of Kirkintilloch.English, German, Jewish (Ashkenazic), Danish, and Dutch : regional name from Holland, a province of the Netherlands.

    Holland

  • Jarry
  • Surname or Lastname

    Southern French

    Jarry

    Southern French : topographic name for someone who lived by an oak tree or oak grove, from Occitan garric (masculine) ‘kermes oak’ or garrique (feminine) ‘grove of kermes oaks’.English (Norfolk) : variant of Geary 2.A bearer with the secondary surname Lahaye, from the Perche region of France, is documented in Montreal in 1654.

    Jarry

  • Hulin
  • Surname or Lastname

    English (Gloucestershire)

    Hulin

    English (Gloucestershire) : from a pet form of the personal name Hugh.French : from a pet form of Hue (see Hugh).French : from a reduced form of Hudelin, a double diminutive of the personal name Hude (see Houde).Possibly Swedish : from an unidentified first element + the common ornamental suffix -(l)in.A Hulin from the Brie region of France is recorded in Quebec City in 1659.

    Hulin

  • Jourdain
  • Surname or Lastname

    English and French

    Jourdain

    English and French : variant of Jordan.A Jourdain from the Saintonge region of France is recorded in Quebec City in 1676. Another, from the Savoie, is documented in 1688 in Lachine, Quebec, with the secondary surname Lafrizade. A third, from Provence, is documented in Champlain, Quebec, in 1688; and another, also called Labrosse, in Montreal in 1696. Other secondary surnames include Bellerose, Lafrance, and Saint-Louis.

    Jourdain

  • Huet
  • Surname or Lastname

    English

    Huet

    English : variant spelling of Hewitt 1.French : from a pet form of the Old French personal name Hue, Hughe (see Hugh).A Huet from the Anjou region of France is recorded in Trois Rivières, Quebec, in 1666, with the secondary surname Dulude.

    Huet

  • Joseph
  • Surname or Lastname

    English, German, French, and Jewish

    Joseph

    English, German, French, and Jewish : from the personal name, Hebrew Yosef ‘may He (God) add (another son)’. In medieval Europe this name was borne frequently but not exclusively by Jews; the usual medieval English vernacular form is represented by Jessup. In the Book of Genesis, Joseph is the favorite son of Jacob, who is sold into slavery by his brothers but rises to become a leading minister in Egypt (Genesis 37–50). In the New Testament Joseph is the husband of the Virgin Mary, which accounts for the popularity of the given name among Christians.A bearer of the name Joseph with the secondary surname Langoumois (and therefore presumably from the Angoumois region of France) is documented in Quebec City in 1718.

    Joseph

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Online names & meanings

  • Madhurank
  • Boy/Male

    Bengali, Hindu, Indian, Marathi, Traditional

    Madhurank

    Honey Bee; Lover

  • OMRI
  • Male

    English

    OMRI

    Anglicized form of Hebrew Omriy, OMRI means "pupil of Jehovah" or "servant of Jehovah." In the bible, this is the name of several characters, including a king of Israel.

  • TILDE
  • Female

    French

    TILDE

    Short form of Norman French Matilde, TILDE means "mighty in battle."

  • Wakeford
  • Surname or Lastname

    English

    Wakeford

    English : habitational name, possibly a variant of Wakefield; otherwise from a lost or unidentified place.

  • Owain
  • Boy/Male

    British, English, Greek, Swedish, Welsh

    Owain

    Well Born; Born from the Yew Tree; Youth

  • Prashan | ப்ரஷந
  • Boy/Male

    Tamil

    Prashan | ப்ரஷந

    Winner

  • Vithushan | விதுஷண
  • Boy/Male

    Tamil

    Vithushan | விதுஷண

  • Gurmithra
  • Girl/Female

    Indian, Punjabi, Sikh, Tamil

    Gurmithra

    Gods Friend

  • Abdus
  • Boy/Male

    Indian

    Abdus

    A narrator of Hadith

  • ZEBUWLUWN
  • Male

    Hebrew

    ZEBUWLUWN

    (זְבֻלוּן) Hebrew name ZEBUWLUWN means "habitation." In the bible, this is the name of the tenth son of Jacob and Leah.

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Other words and meanings similar to

HYPERVARIABLE REGION

AI search in online dictionary sources & meanings containing HYPERVARIABLE REGION

HYPERVARIABLE REGION

  • Tropic
  • n.

    The region lying between these parallels of latitude, or near them on either side.

  • Walk
  • n.

    That in or through which one walks; place or distance walked over; a place for walking; a path or avenue prepared for foot passengers, or for taking air and exercise; way; road; hence, a place or region in which animals may graze; place of wandering; range; as, a sheep walk.

  • Traversable
  • a.

    Capable of being traversed, or passed over; as, a traversable region.

  • Vomer
  • n.

    A bone, or one of a pair of bones, beneath the ethmoid region of the skull, forming a part a part of the partition between the nostrils in man and other mammals.

  • Transfer
  • n.

    A pathological process by virtue of which a unilateral morbid condition on being abolished on one side of the body makes its appearance in the corresponding region upon the other side.

  • Sciatic
  • a.

    Of or pertaining to the hip; in the region of, or affecting, the hip; ischial; ischiatic; as, the sciatic nerve, sciatic pains.

  • Turpentine
  • n.

    A semifluid or fluid oleoresin, primarily the exudation of the terebinth, or turpentine, tree (Pistacia Terebinthus), a native of the Mediterranean region. It is also obtained from many coniferous trees, especially species of pine, larch, and fir.

  • Regional
  • a.

    Of or pertaining to a particular region; sectional.

  • Trapezium
  • n.

    A region on the ventral side of the brain, either just back of the pons Varolii, or, as in man, covered by the posterior extension of its transverse fibers.

  • Sagittal
  • a.

    Of or pertaining to the sagittal suture; in the region of the sagittal suture; rabdoidal; as, the sagittal furrow, or groove, on the inner surface of the roof of the skull.

  • Undersky
  • n.

    The lower region of the sky.

  • Scapular
  • n.

    One of a special group of feathers which arise from each of the scapular regions and lie along the sides of the back.

  • Saxifrage
  • n.

    Any plant of the genus Saxifraga, mostly perennial herbs growing in crevices of rocks in mountainous regions.

  • Saphenous
  • a.

    Of, pertaining to, or in the region of, the saphenous veins; as, the saphenous nerves; the saphenous opening, an opening in the broad fascia of the thigh through which the internal saphenous vein passes.

  • Utes
  • n. pl.

    An extensive tribe of North American Indians of the Shoshone stock, inhabiting Colorado, Utah, New Mexico, Arizona, and adjacent regions. They are subdivided into several subordinate tribes, some of which are among the most degraded of North American Indians.

  • Vast
  • n.

    A waste region; boundless space; immensity.

  • Sagebrush
  • n.

    A low irregular shrub (Artemisia tridentata), of the order Compositae, covering vast tracts of the dry alkaline regions of the American plains; -- called also sagebush, and wild sage.

  • Transcend
  • v. t.

    To rise above; to surmount; as, lights in the heavens transcending the region of the clouds.

  • Transalpine
  • a.

    Being on the farther side of the Alps in regard to Rome, that is, on the north or west side of the Alps; of or pertaining to the region or the people beyond the Alps; as, transalpine Gaul; -- opposed to cisalpine.

  • Turcoman
  • n.

    A member of a tribe of Turanians inhabiting a region east of the Caspian Sea.