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OREXIN RECEPTOR-TYPE-2

  • Orexin receptor type 2
  • Protein-coding gene in the species Homo sapiens

    Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2 (HcrtR2), is a protein that in humans is encoded by the HCRTR2 gene. It

    Orexin receptor type 2

    Orexin receptor type 2

    Orexin_receptor_type_2

  • Orexin receptor
  • G-protein-coupled receptor

    However, orexin-B shows a 5- to 10-fold selectivity for orexin receptor type 2, whilst orexin-A is equipotent at both receptors. Several orexin receptor antagonists

    Orexin receptor

    Orexin_receptor

  • Orexin
  • Neuropeptide that regulates arousal, wakefulness, and appetite

    feeding, and other behaviours. There are two types of orexin peptide and two types of orexin receptor. Orexin was discovered in 1998 almost simultaneously

    Orexin

    Orexin

    Orexin

  • Hypocretin (orexin) receptor 1
  • Protein found in humans

    Orexin receptor type 1 (Ox1R or OX1), also known as hypocretin receptor type 1 (HcrtR1), is a protein that in humans is encoded by the HCRTR1 gene. The

    Hypocretin (orexin) receptor 1

    Hypocretin (orexin) receptor 1

    Hypocretin_(orexin)_receptor_1

  • List of investigational insomnia drugs
  • Investigational insomnia drugs

    – orexin OX1 and OX2 receptor antagonist HEC-83518 – orexin receptor antagonist IN-AQUL-001 – undefined mechanism of action JNJ-48816274 – orexin OX2

    List of investigational insomnia drugs

    List_of_investigational_insomnia_drugs

  • Narcolepsy
  • Chronic neurological sleep disorder

    forms of narcolepsy: type 1 and type 2. Narcolepsy type 1 features EDS with either cataplexy or cerebrospinal fluid (CSF) orexin levels of less than 110

    Narcolepsy

    Narcolepsy

    Narcolepsy

  • Beta-2 adrenergic receptor
  • Mammalian protein found in humans

    asthma, obesity and type 2 diabetes. The 3D crystallographic structure (see figure and links to the right) of the β2-adrenergic receptor has been determined

    Beta-2 adrenergic receptor

    Beta-2 adrenergic receptor

    Beta-2_adrenergic_receptor

  • Oveporexton
  • Medication

    urgency to urinate, and increased saliva production. Oveporexton is an orexin OX2 receptor agonist. Oveporexton was approved for medical use in China in July

    Oveporexton

    Oveporexton

    Oveporexton

  • List of investigational narcolepsy and hypersomnia drugs
  • Investigational narcolepsy and hypersomnia drugs

    (TRN-257) – GABAB receptor agonist and GHB receptor agonist – narcolepsy, idiopathic hypersomnia [2] Alixorexton (ALKS-2680) – orexin OX2 receptor agonist – narcolepsy

    List of investigational narcolepsy and hypersomnia drugs

    List_of_investigational_narcolepsy_and_hypersomnia_drugs

  • Melanocortin receptor
  • G protein-coupled receptor

    Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin

    Melanocortin receptor

    Melanocortin_receptor

  • Angiotensin II receptor type 2
  • Protein-coding gene in humans

    Angiotensin II receptor type 2, also known as the AT2 receptor, is a protein that in humans is encoded by the AGTR2 gene. Angiotensin II is a potent pressor

    Angiotensin II receptor type 2

    Angiotensin II receptor type 2

    Angiotensin_II_receptor_type_2

  • Vasopressin receptor 2
  • Protein-coding gene in the species Homo sapiens

    Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. AVPR2 belongs

    Vasopressin receptor 2

    Vasopressin receptor 2

    Vasopressin_receptor_2

  • Alixorexton
  • Novel chemistry compound

    it is in phase 2 clinical trials with planned advancement to a phase 3 study for the treatment of narcolepsy type 1. Orexin receptor § Agonists List

    Alixorexton

    Alixorexton

    Alixorexton

  • Wakefulness-promoting agent
  • Drug that increases wakefulness

    and istradefylline Histamine H3 receptor antagonists and inverse agonists like pitolisant and samelisant Orexin receptor agonists like danavorexton and

    Wakefulness-promoting agent

    Wakefulness-promoting agent

    Wakefulness-promoting_agent

  • Cannabinoid receptor 2
  • Mammalian protein found in humans

    The cannabinoid receptor 2 (CB2) is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It is

    Cannabinoid receptor 2

    Cannabinoid receptor 2

    Cannabinoid_receptor_2

  • Suvorexant
  • Medication used to treat insomnia

    Suvorexant is a dual orexin receptor antagonist (DORA). It acts as a selective dual antagonist of the orexin OX1 and OX2 receptors. The medication has

    Suvorexant

    Suvorexant

    Suvorexant

  • Lateral hypothalamus
  • Brain region

    cannabinoid receptor 1 (CB1) is colocalized on orexinergic projection neurons in the lateral hypothalamus and many output structures, where the CB1 and orexin receptor

    Lateral hypothalamus

    Lateral hypothalamus

    Lateral_hypothalamus

  • Hypnotic
  • Drug whose use induces sleep

    Orexin receptor antagonists are drugs that block the orexin OX1 and/or OX2 receptors, hence reducing the wakefulness-promoting effects of the orexin system

    Hypnotic

    Hypnotic

    Hypnotic

  • Acetylcholine receptor
  • Integral membrane protein

    An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine,

    Acetylcholine receptor

    Acetylcholine receptor

    Acetylcholine_receptor

  • Histamine H1 receptor
  • Histamine receptor

    The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. This receptor is activated by the biogenic

    Histamine H1 receptor

    Histamine H1 receptor

    Histamine_H1_receptor

  • Cluster headache
  • Neurological disorder

    that are thought to play a role in the disease are the hypocretin/orexin receptor type 2 (HCRTR2), alcohol dehydrogenase 4 (ADH4), β3 subunit of G proteins

    Cluster headache

    Cluster headache

    Cluster_headache

  • Angiotensin II receptor type 1
  • Protein found in humans

    Angiotensin II receptor type 1 (AT1) is a Gq/11-coupled G protein-coupled receptor (GPCR) and the best characterized angiotensin receptor. It is encoded

    Angiotensin II receptor type 1

    Angiotensin II receptor type 1

    Angiotensin_II_receptor_type_1

  • Calcitonin receptor
  • Protein found in humans

    and calcitonin receptor agonists may be more effective than amylin receptor agonists for obesity and type II diabetes. Calcitonin receptor has been shown

    Calcitonin receptor

    Calcitonin receptor

    Calcitonin_receptor

  • Dopaminergic pathways
  • Projection neurons in the brain that synthesize and release dopamine

    Biophysical Research Communications. 445 (2): 486–90. doi:10.1016/j.bbrc.2014.02.026. PMID 24530395. Orexin receptor subtypes readily formed homo- and hetero(di)mers

    Dopaminergic pathways

    Dopaminergic pathways

    Dopaminergic_pathways

  • Alpha-2 adrenergic receptor
  • Protein family

    The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists

    Alpha-2 adrenergic receptor

    Alpha-2 adrenergic receptor

    Alpha-2_adrenergic_receptor

  • List of psychoactive drugs
  • Muscarinic acetylcholine receptor agonists (e.g., arecoline) Nicotinic acetylcholine receptor agonists (e.g., nicotine) Orexin receptor agonists (e.g., danavorexton

    List of psychoactive drugs

    List_of_psychoactive_drugs

  • Neurotransmitter
  • Chemical substance that enables neurotransmission

    405–11. doi:10.1016/j.mad.2011.06.005. PMC 3367503. PMID 21729715. Orexin receptor antagonists a new class of sleeping pill, National Sleep Foundation

    Neurotransmitter

    Neurotransmitter

    Neurotransmitter

  • Somatostatin receptor 2
  • Protein-coding gene in the species Homo sapiens

    Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. The SSTR2 gene is located on chromosome 17 on the long arm in position

    Somatostatin receptor 2

    Somatostatin receptor 2

    Somatostatin_receptor_2

  • Taste receptor
  • Type of cellular receptor that facilitates taste

    A taste receptor is a type of cellular receptor that facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact

    Taste receptor

    Taste receptor

    Taste_receptor

  • Cannabinoid receptor 1
  • Mammalian protein found in humans

    Cannabinoid receptor 1 (CB1), is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. It was discovered by determination

    Cannabinoid receptor 1

    Cannabinoid receptor 1

    Cannabinoid_receptor_1

  • Endothelin receptor type B
  • Protein-coding gene in the species Homo sapiens

    Endothelin receptor type B, (ET-B) is a protein that in humans is encoded by the EDNRB gene. Endothelin receptor type B is a G protein-coupled receptor which

    Endothelin receptor type B

    Endothelin receptor type B

    Endothelin_receptor_type_B

  • Growth hormone secretagogue receptor
  • Protein-coding gene in the species Homo sapiens

    receptors: somatostatin receptor 5, dopamine receptor type 2 (DRD2), melanocortin-3 receptor (MC3R), and serotonin receptor type 2C (5-HT2c receptor)

    Growth hormone secretagogue receptor

    Growth hormone secretagogue receptor

    Growth_hormone_secretagogue_receptor

  • Endocannabinoid system
  • Biological system of neurotransmitters

    colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1)

    Endocannabinoid system

    Endocannabinoid system

    Endocannabinoid_system

  • Danavorexton
  • Chemical compound

    Danavorexton (developmental code name TAK-925) is a selective orexin 2 receptor agonist. It is a small-molecule compound and is administered intravenously

    Danavorexton

    Danavorexton

    Danavorexton

  • Metabotropic glutamate receptor
  • Type of glutamate receptor

    The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members

    Metabotropic glutamate receptor

    Metabotropic glutamate receptor

    Metabotropic_glutamate_receptor

  • G protein-coupled receptor
  • Class of cell surface receptors coupled to G-protein-associated intracellular signaling

    protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G

    G protein-coupled receptor

    G protein-coupled receptor

    G_protein-coupled_receptor

  • Amphetamine
  • Central nervous system stimulant

    emotion, and learning. In fact, orexin is thought to promote feeding primarily by promoting arousal. Mutations in orexin receptors are responsible for narcolepsy

    Amphetamine

    Amphetamine

    Amphetamine

  • Tropomyosin receptor kinase B
  • Protein and coding gene in humans

    neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene. TrkB is a receptor for brain-derived neurotrophic factor

    Tropomyosin receptor kinase B

    Tropomyosin receptor kinase B

    Tropomyosin_receptor_kinase_B

  • Alkermes plc
  • Irish-domiciled healthcare company

    In October 2023, Alkermes announced its first data related to its orexin 2 receptor (OXR2) agonist, alixorexton, previously known as ALKS 2680. Alixorexton

    Alkermes plc

    Alkermes_plc

  • Alpha-adrenergic agonist
  • Class of drugs

    selectively stimulate alpha adrenergic receptors. The alpha-adrenergic receptor has two subclasses, α1 and α2. Alpha 2 receptors are associated with sympatholytic

    Alpha-adrenergic agonist

    Alpha-adrenergic agonist

    Alpha-adrenergic_agonist

  • GABA receptor
  • Receptors that respond to gamma-aminobutyric acid

    of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled

    GABA receptor

    GABA receptor

    GABA_receptor

  • Adrenergic receptor
  • Class of G protein-coupled receptors

    beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example. Many cells have these receptors, and

    Adrenergic receptor

    Adrenergic receptor

    Adrenergic_receptor

  • Metabotropic receptor
  • Type of membrane receptor that acts through a second messenger

    A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic

    Metabotropic receptor

    Metabotropic_receptor

  • Firazorexton
  • Chemical compound

    Nonproprietary Name; development code TAK-994) is an experimental orexin 2 (OX2) receptor agonist first described in a 2019 patent filed by Takeda Pharmaceutical

    Firazorexton

    Firazorexton

    Firazorexton

  • Angiotensin II receptor
  • Class of G protein-coupled receptors

    "The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophy"

    Angiotensin II receptor

    Angiotensin_II_receptor

  • Neuropeptide Y receptor type 2
  • Protein-coding gene in the species Homo sapiens

    Neuropeptide Y receptor type 2 (Y2R) is a member of the neuropeptide Y receptor family of G-protein coupled receptors, that in humans is encoded by the

    Neuropeptide Y receptor type 2

    Neuropeptide Y receptor type 2

    Neuropeptide_Y_receptor_type_2

  • List of investigational anxiety disorder drugs
  • Investigational anxiety disorder drugs

    Tebideutorexant (JNJ-3215; JNJ-61393215; Orexin-1) – orexin OX1 receptor antagonist [57] WAY-100135 – serotonin 5-HT1A receptor antagonist [58] Ziprasidone (CP-88059-01;

    List of investigational anxiety disorder drugs

    List_of_investigational_anxiety_disorder_drugs

  • Free fatty acid receptor 1
  • Protein-coding gene in the species Homo sapiens

    Free fatty acid receptor 1 (FFAR1), also known as G-protein coupled receptor 40 (GPR40), is a rhodopsin-like G-protein coupled receptor that is coded (i

    Free fatty acid receptor 1

    Free fatty acid receptor 1

    Free_fatty_acid_receptor_1

  • Lisdexamfetamine
  • Central nervous system stimulant prodrug

    emotion, and learning. In fact, orexin is thought to promote feeding primarily by promoting arousal. Mutations in orexin receptors are responsible for narcolepsy

    Lisdexamfetamine

    Lisdexamfetamine

    Lisdexamfetamine

  • Neurotransmitter receptor
  • Type of protein

    A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside

    Neurotransmitter receptor

    Neurotransmitter receptor

    Neurotransmitter_receptor

  • Muscarinic acetylcholine receptor
  • Acetylcholine receptors named for their selective binding of muscarine

    Muscarinic acetylcholine receptors (mAChRs) are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain

    Muscarinic acetylcholine receptor

    Muscarinic acetylcholine receptor

    Muscarinic_acetylcholine_receptor

  • Melanocortin 1 receptor
  • Protein controlling mammalian coloration

    melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a

    Melanocortin 1 receptor

    Melanocortin 1 receptor

    Melanocortin_1_receptor

  • Cannabinoid receptor
  • Group of receptors to cannabinoid compounds

    to determination in 1993 of a second brain cannabinoid receptor named cannabinoid receptor type 2 or CB2. A neurotransmitter for a possible endocannabinoid

    Cannabinoid receptor

    Cannabinoid receptor

    Cannabinoid_receptor

  • Rhodopsin-like receptors
  • Family of proteins

    Neuropeptide FF receptor 1 (NPFFR1, FF1R) Neuropeptide FF receptor 2 (NPFFR2, FF2R) Orexin receptor InterPro: IPR000204 Hypocretin (orexin) receptor 1 (HCRTR1

    Rhodopsin-like receptors

    Rhodopsin-like receptors

    Rhodopsin-like_receptors

  • Free fatty acid receptor 4
  • Protein-coding gene in the species Homo sapiens

    Free Fatty acid receptor 4 (FFAR4), also termed G-protein coupled receptor 120 (GPR120), is a protein that in humans is encoded (i.e., its formation is

    Free fatty acid receptor 4

    Free fatty acid receptor 4

    Free_fatty_acid_receptor_4

  • Κ-opioid receptor
  • Protein-coding gene in the species Homo sapiens, named for ketazocine

    Besides KOR-DOR the receptor heterodimerizes with μ-opioid (preferentially forms in females), nociceptin (NOP), orexin receptor 1 (OX1), dopamine transporter

    Κ-opioid receptor

    Κ-opioid receptor

    Κ-opioid_receptor

  • Dopamine receptor D1
  • Protein-coding gene in humans

    Dopamine receptor D1, also known as DRD1, is one of the two types of D1-like receptor family—receptors D1 and D5. It is a protein that in humans is encoded

    Dopamine receptor D1

    Dopamine receptor D1

    Dopamine_receptor_D1

  • Adderall
  • Drug mixture used mainly to treat ADHD and narcolepsy

    either type 1 or type 2, with only the former presenting cataplexy symptoms. Type 1 narcolepsy results from the loss of approximately 70,000 orexin-releasing

    Adderall

    Adderall

    Adderall

  • Glucagon-like peptide-1 receptor
  • Receptor activated by peptide hormone GLP-1

    PF-06372222 GLP-1 receptor agonists are a class of medications that mimic the actions of the endogenous incretin hormone GLP-1, and are used in type 2 diabetes

    Glucagon-like peptide-1 receptor

    Glucagon-like peptide-1 receptor

    Glucagon-like_peptide-1_receptor

  • Muscarinic acetylcholine receptor M2
  • Receptor protein found in humans

    muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded

    Muscarinic acetylcholine receptor M2

    Muscarinic acetylcholine receptor M2

    Muscarinic_acetylcholine_receptor_M2

  • Histamine H2 receptor
  • Mammalian protein found in Homo sapiens

    H2 receptors are a type of histamine receptor found in many parts of the anatomy of humans and other animals. They are positively coupled to adenylate

    Histamine H2 receptor

    Histamine H2 receptor

    Histamine_H2_receptor

  • Mu-opioid receptor
  • Class of opioid receptors found in humans

    The μ-opioid receptors (using the Greek letter mu, abbreviated MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin

    Mu-opioid receptor

    Mu-opioid receptor

    Mu-opioid_receptor

  • GABAB receptor
  • G-protein coupled receptor

    GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA). GABAB receptors are found in the central nervous system and

    GABAB receptor

    GABAB_receptor

  • List of investigational headache and migraine drugs
  • Investigational antimigraine drugs

    (MK-6096) – orexin OX1 and OX2 receptor antagonist – migraine [49] Flunarizine (XEN-007) – calcium channel blocker, non-selective monoamine receptor modulator

    List of investigational headache and migraine drugs

    List_of_investigational_headache_and_migraine_drugs

  • Alpha-1 adrenergic receptor
  • G protein-coupled receptor

    The alpha-1 (α1) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G protein. It consists

    Alpha-1 adrenergic receptor

    Alpha-1_adrenergic_receptor

  • Melatonin receptor 1B
  • Protein found in humans

    Melatonin receptor 1B, also known as MTNR1B, is a protein that in humans is encoded by the MTNR1B gene. This gene encodes the MT2 protein, one of two high-affinity

    Melatonin receptor 1B

    Melatonin receptor 1B

    Melatonin_receptor_1B

  • 5-HT2A receptor
  • Subtype of serotonin receptor

    5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)

    5-HT2A receptor

    5-HT2A receptor

    5-HT2A_receptor

  • Alpha-1A adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and

    Alpha-1A adrenergic receptor

    Alpha-1A adrenergic receptor

    Alpha-1A_adrenergic_receptor

  • Muscarinic acetylcholine receptor M3
  • Protein and coding gene in humans

    acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the

    Muscarinic acetylcholine receptor M3

    Muscarinic acetylcholine receptor M3

    Muscarinic_acetylcholine_receptor_M3

  • Dopamine receptor D4
  • Protein-coding gene in the species Homo sapiens

    The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4 has

    Dopamine receptor D4

    Dopamine receptor D4

    Dopamine_receptor_D4

  • Opsin
  • Class of light-sensitive proteins

    opsins (also known as type 2 opsins) are members of the seven-transmembrane-domain proteins of the G protein-coupled receptor (GPCR) superfamily. Animal

    Opsin

    Opsin

    Opsin

  • Cysteinyl leukotriene receptor 1
  • Protein-coding gene in humans

    Cysteinyl leukotriene receptor 1, also termed CYSLTR1, is a receptor for cysteinyl leukotrienes (LT) (see cysteinyl leukotrienes). CYSLTR1, by binding

    Cysteinyl leukotriene receptor 1

    Cysteinyl leukotriene receptor 1

    Cysteinyl_leukotriene_receptor_1

  • Hydroxycarboxylic acid receptor 3
  • Protein-coding gene in the species Homo sapiens

    Hydroxycarboxylic acid receptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B, is a protein which in humans is encoded by the HCAR3 gene

    Hydroxycarboxylic acid receptor 3

    Hydroxycarboxylic acid receptor 3

    Hydroxycarboxylic_acid_receptor_3

  • Protease-activated receptor
  • Subfamily of related G protein-coupled receptors

    across a range of tissues and cell types. They are also members of the seven-transmembrane G-protein-coupled receptor superfamily, and are expressed throughout

    Protease-activated receptor

    Protease-activated_receptor

  • Apelin receptor
  • Protein-coding gene in the species Homo sapiens

    The Apelin Receptor is a G protein-coupled receptor which in humans is encoded by the gene APLNR (and also known as APJ). The structure of APLNR was resolved

    Apelin receptor

    Apelin receptor

    Apelin_receptor

  • Histamine H4 receptor
  • Mammalian protein found in Homo sapiens

    The histamine H4 receptor, like the other three histamine receptors, is a member of the G protein-coupled receptor superfamily that in humans is encoded

    Histamine H4 receptor

    Histamine H4 receptor

    Histamine_H4_receptor

  • Follicle-stimulating hormone receptor
  • Protein-coding gene in the species Homo sapiens

    The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH)

    Follicle-stimulating hormone receptor

    Follicle-stimulating hormone receptor

    Follicle-stimulating_hormone_receptor

  • Parathyroid hormone receptor
  • There are two known parathyroid hormone receptors in mammals termed PTH1R and PTH2R. These receptors bind parathyroid hormone and are members of the GPCR

    Parathyroid hormone receptor

    Parathyroid_hormone_receptor

  • Histamine receptor
  • Class of receptor proteins that bind histamine

    physiological processes. There are four main types of histamine receptors: H1, H2, H3, and H4. H1 receptors are linked to allergic responses, H2 to gastric

    Histamine receptor

    Histamine receptor

    Histamine_receptor

  • Dextroamphetamine
  • CNS stimulant and isomer of amphetamine

    either type 1 or type 2, with only the former presenting cataplexy symptoms. Type 1 narcolepsy results from the loss of approximately 70,000 orexin-releasing

    Dextroamphetamine

    Dextroamphetamine

    Dextroamphetamine

  • Growth-hormone-releasing hormone receptor
  • Receptor protein that binds with somatcrinin

    The growth-hormone-releasing hormone receptor (GHRHR) is a G-protein-coupled receptor that binds growth hormone-releasing hormone. The GHRHR activates

    Growth-hormone-releasing hormone receptor

    Growth-hormone-releasing hormone receptor

    Growth-hormone-releasing_hormone_receptor

  • Glutamate receptor
  • Neuron membrane protein

    Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base

    Glutamate receptor

    Glutamate receptor

    Glutamate_receptor

  • Hydroxycarboxylic acid receptor 2
  • Protein-coding gene in the species Homo sapiens

    Hydroxycarboxylic acid receptor 2 (HCA2), also known as GPR109A and niacin receptor 1 (NIACR1), is a protein which in humans is encoded (its formation

    Hydroxycarboxylic acid receptor 2

    Hydroxycarboxylic acid receptor 2

    Hydroxycarboxylic_acid_receptor_2

  • Prostaglandin EP2 receptor
  • Protein-coding gene in the species Homo sapiens

    Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of

    Prostaglandin EP2 receptor

    Prostaglandin EP2 receptor

    Prostaglandin_EP2_receptor

  • Calcium-sensing receptor
  • Mammalian protein found in humans

    The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ions. It is primarily expressed

    Calcium-sensing receptor

    Calcium-sensing receptor

    Calcium-sensing_receptor

  • Olfactory receptor
  • Chemoreceptors expressed in cell membranes of olfactory receptor neurons

    Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible

    Olfactory receptor

    Olfactory receptor

    Olfactory_receptor

  • Neurotensin receptor 2
  • Protein found in humans

    receptor type 2 is a protein that in humans is encoded by the NTSR2 gene. The protein encoded by this gene belongs to the G protein-coupled receptor family

    Neurotensin receptor 2

    Neurotensin receptor 2

    Neurotensin_receptor_2

  • Bombesin receptor
  • Type of G-protein coupled receptor

    The bombesin receptors are a group of G-protein coupled receptors which bind bombesin. Three bombesin receptors are currently known: BB1, previously known

    Bombesin receptor

    Bombesin_receptor

  • Glucagon receptor
  • Protein-coding gene in the species Homo sapiens

    the GCGR gene is associated with diabetes mellitus type 2. Inactivating mutation of glucagon receptor in humans causes resistance to glucagon and is associated

    Glucagon receptor

    Glucagon receptor

    Glucagon_receptor

  • Endothelin receptor
  • G protein-coupled receptor

    are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation

    Endothelin receptor

    Endothelin_receptor

  • Melanin-concentrating hormone
  • Protein-coding gene in the species Homo sapiens

    Melanin-concentrating hormone receptor (MCHR) Melanin-concentrating hormone receptor 1 (MCHR1) Melanin-concentrating hormone receptor 2 (MCHR2) Orexin (OX) GRCh38: Ensembl

    Melanin-concentrating hormone

    Melanin-concentrating hormone

    Melanin-concentrating_hormone

  • Prostaglandin DP2 receptor
  • Protein-coding gene in the species Homo sapiens

    Prostanoid receptors (see Eicosanoid receptor#Prostenoid receptors). DP2 was found to stimulate the directed movement or chemotaxis of human T-helper type 2 cells

    Prostaglandin DP2 receptor

    Prostaglandin DP2 receptor

    Prostaglandin_DP2_receptor

  • Adhesion G protein-coupled receptor
  • Class of 33 human protein receptors

    Adhesion G protein-coupled receptors (adhesion GPCRs) are a class of 33 human protein receptors with a broad distribution in embryonic and larval cells

    Adhesion G protein-coupled receptor

    Adhesion G protein-coupled receptor

    Adhesion_G_protein-coupled_receptor

  • Trace amine-associated receptor
  • Class of G protein-coupled receptors

    amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a family of G protein-coupled receptors that were discovered

    Trace amine-associated receptor

    Trace_amine-associated_receptor

  • Muscarinic acetylcholine receptor M1
  • Protein-coding gene in the species Homo sapiens

    The Muscarinic Acetylcholine receptor M1, also known as the Cholinergic receptor, Muscarinic 1, is a muscarinic receptor that in humans is encoded by

    Muscarinic acetylcholine receptor M1

    Muscarinic acetylcholine receptor M1

    Muscarinic_acetylcholine_receptor_M1

  • Lysophosphatidic acid receptor
  • Index of articles associated with the same name

    acid receptor 2 (LPAR2; formerly known as EDG4) Lysophosphatidic acid receptor 3 (LPAR3; formerly known as EDG7) Lysophosphatidic acid receptor 4 (LPAR4;

    Lysophosphatidic acid receptor

    Lysophosphatidic_acid_receptor

  • Vasopressin receptor
  • G protein-coupled receptor

    G protein-coupled receptors (GPCRs) called vasopressin receptors that are classified into the V1 (V1A), V2, and V3 (V1B) receptor subtypes. These three

    Vasopressin receptor

    Vasopressin_receptor

  • Dopamine receptor
  • Class of G protein-coupled receptors

    dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. The existence of multiple types of receptors for

    Dopamine receptor

    Dopamine receptor

    Dopamine_receptor

  • Pediatric narcolepsy
  • Sleep disorder in children

    various areas brain through its interaction with orexin receptors, a type of G protein-coupled receptor. Importantly, the dorsal raphe nucleus, locus coeruleus

    Pediatric narcolepsy

    Pediatric_narcolepsy

  • Dopamine receptor D3
  • Subtype of Dopamine Receptor

    Dopamine receptor D3 (DRD3) is a protein belonging to the dopamine receptor family of G protein-coupled receptors. In humans, it is encoded by the DRD3

    Dopamine receptor D3

    Dopamine receptor D3

    Dopamine_receptor_D3

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  • Tyre
  • Boy/Male

    Biblical Latin

    Tyre

    Strength; rock; sharp.

    Tyre

  • Tope
  • Surname or Lastname

    English (Devon)

    Tope

    English (Devon) : unexplained.

    Tope

  • Tyre
  • Girl/Female

    Danish, German, Swedish

    Tyre

    A City in Phoenicia

    Tyre

  • Trewin
  • Surname or Lastname

    English (Cornish)

    Trewin

    English (Cornish) : habitational name from Trewin in Cornwall.

    Trewin

  • Brahman
  • Boy/Male

    Indian, Sanskrit

    Brahman

    The Preceptor

    Brahman

  • Tyne
  • Girl/Female

    Christian & English(British/American/Australian)

    Tyne

    River

    Tyne

  • Tyce
  • Boy/Male

    English French

    Tyce

    Fiery.

    Tyce

  • Tyre
  • Surname or Lastname

    Scottish

    Tyre

    Scottish : reduced form of McIntyre.English : variant spelling of Tyer.

    Tyre

  • Muallam
  • Boy/Male

    Arabic

    Muallam

    Educator; Preceptor

    Muallam

  • Tyne
  • Girl/Female

    English

    Tyne

    River.

    Tyne

  • TYE
  • Male

    English

    TYE

    English surname transferred to forename use, derived from the Middle English word tye, TYE means "pasture."

    TYE

  • BRENIN
  • Male

    Welsh

    BRENIN

    Welsh form of Celtic Brennus, BRENIN means "king."

    BRENIN

  • Tye
  • Surname or Lastname

    English (mainly East Anglia)

    Tye

    English (mainly East Anglia) : topographic name for someone who lived by a common pasture, Middle English tye (Old English tēag).North German : from a short form, Tide, of the personal name Dietrich.

    Tye

  • Brewin
  • Surname or Lastname

    English (Leicestershire)

    Brewin

    English (Leicestershire) : of uncertain origin; perhaps variant spelling of Bruin, or alternatively the Irish name (see 2).Irish : Anglicized form of Gaelic Ó Braion ‘descendant of Braon’, a byname meaning ‘moisture’, ‘drop’.

    Brewin

  • Tyne
  • Girl/Female

    American, British, English, Jamaican

    Tyne

    A River in England; River

    Tyne

  • ORRIN
  • Male

    English

    ORRIN

    Variant spelling of English Oran, ORRIN means "little sallow one."

    ORRIN

  • OWEIN
  • Male

    Welsh

    OWEIN

    Variant spelling of Welsh Owain, OWEIN means "born of yew."

    OWEIN

  • TYKE
  • Male

    Danish

    TYKE

    , a female dog; or, the mad, raging.

    TYKE

  • TYGE
  • Male

    Danish

    TYGE

    , a female dog; or, the mad, raging.

    TYGE

  • Tyne
  • Surname or Lastname

    Irish

    Tyne

    Irish : reduced Anglicized form of Gaelic Ó Teimhin ‘descendant of Teimhean’, from teimhean ‘dark’, an adjective from teimhe ‘dusk’, ‘darkness’.English : probably a habitational name for someone from Tyneside in northeast England.

    Tyne

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