Search references for OREXIN RECEPTOR-TYPE-2. Phrases containing OREXIN RECEPTOR-TYPE-2
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Protein-coding gene in the species Homo sapiens
Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2 (HcrtR2), is a protein that in humans is encoded by the HCRTR2 gene. It
Orexin_receptor_type_2
G-protein-coupled receptor
However, orexin-B shows a 5- to 10-fold selectivity for orexin receptor type 2, whilst orexin-A is equipotent at both receptors. Several orexin receptor antagonists
Orexin_receptor
Neuropeptide that regulates arousal, wakefulness, and appetite
feeding, and other behaviours. There are two types of orexin peptide and two types of orexin receptor. Orexin was discovered in 1998 almost simultaneously
Orexin
Protein found in humans
Orexin receptor type 1 (Ox1R or OX1), also known as hypocretin receptor type 1 (HcrtR1), is a protein that in humans is encoded by the HCRTR1 gene. The
Hypocretin (orexin) receptor 1
Hypocretin_(orexin)_receptor_1
Investigational insomnia drugs
– orexin OX1 and OX2 receptor antagonist HEC-83518 – orexin receptor antagonist IN-AQUL-001 – undefined mechanism of action JNJ-48816274 – orexin OX2
List of investigational insomnia drugs
List_of_investigational_insomnia_drugs
Chronic neurological sleep disorder
forms of narcolepsy: type 1 and type 2. Narcolepsy type 1 features EDS with either cataplexy or cerebrospinal fluid (CSF) orexin levels of less than 110
Narcolepsy
Mammalian protein found in humans
asthma, obesity and type 2 diabetes. The 3D crystallographic structure (see figure and links to the right) of the β2-adrenergic receptor has been determined
Beta-2_adrenergic_receptor
Medication
urgency to urinate, and increased saliva production. Oveporexton is an orexin OX2 receptor agonist. Oveporexton was approved for medical use in China in July
Oveporexton
Investigational narcolepsy and hypersomnia drugs
(TRN-257) – GABAB receptor agonist and GHB receptor agonist – narcolepsy, idiopathic hypersomnia [2] Alixorexton (ALKS-2680) – orexin OX2 receptor agonist – narcolepsy
List of investigational narcolepsy and hypersomnia drugs
List_of_investigational_narcolepsy_and_hypersomnia_drugs
G protein-coupled receptor
Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin
Melanocortin_receptor
Protein-coding gene in humans
Angiotensin II receptor type 2, also known as the AT2 receptor, is a protein that in humans is encoded by the AGTR2 gene. Angiotensin II is a potent pressor
Angiotensin II receptor type 2
Angiotensin_II_receptor_type_2
Protein-coding gene in the species Homo sapiens
Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. AVPR2 belongs
Vasopressin_receptor_2
Novel chemistry compound
it is in phase 2 clinical trials with planned advancement to a phase 3 study for the treatment of narcolepsy type 1. Orexin receptor § Agonists List
Alixorexton
Drug that increases wakefulness
and istradefylline Histamine H3 receptor antagonists and inverse agonists like pitolisant and samelisant Orexin receptor agonists like danavorexton and
Wakefulness-promoting_agent
Mammalian protein found in humans
The cannabinoid receptor 2 (CB2) is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It is
Cannabinoid_receptor_2
Medication used to treat insomnia
Suvorexant is a dual orexin receptor antagonist (DORA). It acts as a selective dual antagonist of the orexin OX1 and OX2 receptors. The medication has
Suvorexant
Brain region
cannabinoid receptor 1 (CB1) is colocalized on orexinergic projection neurons in the lateral hypothalamus and many output structures, where the CB1 and orexin receptor
Lateral_hypothalamus
Drug whose use induces sleep
Orexin receptor antagonists are drugs that block the orexin OX1 and/or OX2 receptors, hence reducing the wakefulness-promoting effects of the orexin system
Hypnotic
Integral membrane protein
An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine,
Acetylcholine_receptor
Histamine receptor
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. This receptor is activated by the biogenic
Histamine_H1_receptor
Neurological disorder
that are thought to play a role in the disease are the hypocretin/orexin receptor type 2 (HCRTR2), alcohol dehydrogenase 4 (ADH4), β3 subunit of G proteins
Cluster_headache
Protein found in humans
Angiotensin II receptor type 1 (AT1) is a Gq/11-coupled G protein-coupled receptor (GPCR) and the best characterized angiotensin receptor. It is encoded
Angiotensin II receptor type 1
Angiotensin_II_receptor_type_1
Protein found in humans
and calcitonin receptor agonists may be more effective than amylin receptor agonists for obesity and type II diabetes. Calcitonin receptor has been shown
Calcitonin_receptor
Projection neurons in the brain that synthesize and release dopamine
Biophysical Research Communications. 445 (2): 486–90. doi:10.1016/j.bbrc.2014.02.026. PMID 24530395. Orexin receptor subtypes readily formed homo- and hetero(di)mers
Dopaminergic_pathways
Protein family
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists
Alpha-2_adrenergic_receptor
Muscarinic acetylcholine receptor agonists (e.g., arecoline) Nicotinic acetylcholine receptor agonists (e.g., nicotine) Orexin receptor agonists (e.g., danavorexton
List_of_psychoactive_drugs
Chemical substance that enables neurotransmission
405–11. doi:10.1016/j.mad.2011.06.005. PMC 3367503. PMID 21729715. Orexin receptor antagonists a new class of sleeping pill, National Sleep Foundation
Neurotransmitter
Protein-coding gene in the species Homo sapiens
Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. The SSTR2 gene is located on chromosome 17 on the long arm in position
Somatostatin_receptor_2
Type of cellular receptor that facilitates taste
A taste receptor is a type of cellular receptor that facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact
Taste_receptor
Mammalian protein found in humans
Cannabinoid receptor 1 (CB1), is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. It was discovered by determination
Cannabinoid_receptor_1
Protein-coding gene in the species Homo sapiens
Endothelin receptor type B, (ET-B) is a protein that in humans is encoded by the EDNRB gene. Endothelin receptor type B is a G protein-coupled receptor which
Endothelin_receptor_type_B
Protein-coding gene in the species Homo sapiens
receptors: somatostatin receptor 5, dopamine receptor type 2 (DRD2), melanocortin-3 receptor (MC3R), and serotonin receptor type 2C (5-HT2c receptor)
Growth hormone secretagogue receptor
Growth_hormone_secretagogue_receptor
Biological system of neurotransmitters
colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1)
Endocannabinoid_system
Chemical compound
Danavorexton (developmental code name TAK-925) is a selective orexin 2 receptor agonist. It is a small-molecule compound and is administered intravenously
Danavorexton
Type of glutamate receptor
The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members
Metabotropic glutamate receptor
Metabotropic_glutamate_receptor
Class of cell surface receptors coupled to G-protein-associated intracellular signaling
protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G
G_protein-coupled_receptor
Central nervous system stimulant
emotion, and learning. In fact, orexin is thought to promote feeding primarily by promoting arousal. Mutations in orexin receptors are responsible for narcolepsy
Amphetamine
Protein and coding gene in humans
neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene. TrkB is a receptor for brain-derived neurotrophic factor
Tropomyosin_receptor_kinase_B
Irish-domiciled healthcare company
In October 2023, Alkermes announced its first data related to its orexin 2 receptor (OXR2) agonist, alixorexton, previously known as ALKS 2680. Alixorexton
Alkermes_plc
Class of drugs
selectively stimulate alpha adrenergic receptors. The alpha-adrenergic receptor has two subclasses, α1 and α2. Alpha 2 receptors are associated with sympatholytic
Alpha-adrenergic_agonist
Receptors that respond to gamma-aminobutyric acid
of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled
GABA_receptor
Class of G protein-coupled receptors
beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example. Many cells have these receptors, and
Adrenergic_receptor
Type of membrane receptor that acts through a second messenger
A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic
Metabotropic_receptor
Chemical compound
Nonproprietary Name; development code TAK-994) is an experimental orexin 2 (OX2) receptor agonist first described in a 2019 patent filed by Takeda Pharmaceutical
Firazorexton
Class of G protein-coupled receptors
"The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophy"
Angiotensin_II_receptor
Protein-coding gene in the species Homo sapiens
Neuropeptide Y receptor type 2 (Y2R) is a member of the neuropeptide Y receptor family of G-protein coupled receptors, that in humans is encoded by the
Neuropeptide Y receptor type 2
Neuropeptide_Y_receptor_type_2
Investigational anxiety disorder drugs
Tebideutorexant (JNJ-3215; JNJ-61393215; Orexin-1) – orexin OX1 receptor antagonist [57] WAY-100135 – serotonin 5-HT1A receptor antagonist [58] Ziprasidone (CP-88059-01;
List of investigational anxiety disorder drugs
List_of_investigational_anxiety_disorder_drugs
Protein-coding gene in the species Homo sapiens
Free fatty acid receptor 1 (FFAR1), also known as G-protein coupled receptor 40 (GPR40), is a rhodopsin-like G-protein coupled receptor that is coded (i
Free_fatty_acid_receptor_1
Central nervous system stimulant prodrug
emotion, and learning. In fact, orexin is thought to promote feeding primarily by promoting arousal. Mutations in orexin receptors are responsible for narcolepsy
Lisdexamfetamine
Type of protein
A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside
Neurotransmitter_receptor
Acetylcholine receptors named for their selective binding of muscarine
Muscarinic acetylcholine receptors (mAChRs) are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain
Muscarinic acetylcholine receptor
Muscarinic_acetylcholine_receptor
Protein controlling mammalian coloration
melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a
Melanocortin_1_receptor
Group of receptors to cannabinoid compounds
to determination in 1993 of a second brain cannabinoid receptor named cannabinoid receptor type 2 or CB2. A neurotransmitter for a possible endocannabinoid
Cannabinoid_receptor
Family of proteins
Neuropeptide FF receptor 1 (NPFFR1, FF1R) Neuropeptide FF receptor 2 (NPFFR2, FF2R) Orexin receptor InterPro: IPR000204 Hypocretin (orexin) receptor 1 (HCRTR1
Rhodopsin-like_receptors
Protein-coding gene in the species Homo sapiens
Free Fatty acid receptor 4 (FFAR4), also termed G-protein coupled receptor 120 (GPR120), is a protein that in humans is encoded (i.e., its formation is
Free_fatty_acid_receptor_4
Protein-coding gene in the species Homo sapiens, named for ketazocine
Besides KOR-DOR the receptor heterodimerizes with μ-opioid (preferentially forms in females), nociceptin (NOP), orexin receptor 1 (OX1), dopamine transporter
Κ-opioid_receptor
Protein-coding gene in humans
Dopamine receptor D1, also known as DRD1, is one of the two types of D1-like receptor family—receptors D1 and D5. It is a protein that in humans is encoded
Dopamine_receptor_D1
Drug mixture used mainly to treat ADHD and narcolepsy
either type 1 or type 2, with only the former presenting cataplexy symptoms. Type 1 narcolepsy results from the loss of approximately 70,000 orexin-releasing
Adderall
Receptor activated by peptide hormone GLP-1
PF-06372222 GLP-1 receptor agonists are a class of medications that mimic the actions of the endogenous incretin hormone GLP-1, and are used in type 2 diabetes
Glucagon-like peptide-1 receptor
Glucagon-like_peptide-1_receptor
Receptor protein found in humans
muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded
Muscarinic acetylcholine receptor M2
Muscarinic_acetylcholine_receptor_M2
Mammalian protein found in Homo sapiens
H2 receptors are a type of histamine receptor found in many parts of the anatomy of humans and other animals. They are positively coupled to adenylate
Histamine_H2_receptor
Class of opioid receptors found in humans
The μ-opioid receptors (using the Greek letter mu, abbreviated MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin
Mu-opioid_receptor
G-protein coupled receptor
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA). GABAB receptors are found in the central nervous system and
GABAB_receptor
Investigational antimigraine drugs
(MK-6096) – orexin OX1 and OX2 receptor antagonist – migraine [49] Flunarizine (XEN-007) – calcium channel blocker, non-selective monoamine receptor modulator
List of investigational headache and migraine drugs
List_of_investigational_headache_and_migraine_drugs
G protein-coupled receptor
The alpha-1 (α1) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G protein. It consists
Alpha-1_adrenergic_receptor
Protein found in humans
Melatonin receptor 1B, also known as MTNR1B, is a protein that in humans is encoded by the MTNR1B gene. This gene encodes the MT2 protein, one of two high-affinity
Melatonin_receptor_1B
Subtype of serotonin receptor
5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)
5-HT2A_receptor
Protein-coding gene in the species Homo sapiens
adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and
Alpha-1A_adrenergic_receptor
Protein and coding gene in humans
acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the
Muscarinic acetylcholine receptor M3
Muscarinic_acetylcholine_receptor_M3
Protein-coding gene in the species Homo sapiens
The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4 has
Dopamine_receptor_D4
Class of light-sensitive proteins
opsins (also known as type 2 opsins) are members of the seven-transmembrane-domain proteins of the G protein-coupled receptor (GPCR) superfamily. Animal
Opsin
Protein-coding gene in humans
Cysteinyl leukotriene receptor 1, also termed CYSLTR1, is a receptor for cysteinyl leukotrienes (LT) (see cysteinyl leukotrienes). CYSLTR1, by binding
Cysteinyl leukotriene receptor 1
Cysteinyl_leukotriene_receptor_1
Protein-coding gene in the species Homo sapiens
Hydroxycarboxylic acid receptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B, is a protein which in humans is encoded by the HCAR3 gene
Hydroxycarboxylic acid receptor 3
Hydroxycarboxylic_acid_receptor_3
Subfamily of related G protein-coupled receptors
across a range of tissues and cell types. They are also members of the seven-transmembrane G-protein-coupled receptor superfamily, and are expressed throughout
Protease-activated_receptor
Protein-coding gene in the species Homo sapiens
The Apelin Receptor is a G protein-coupled receptor which in humans is encoded by the gene APLNR (and also known as APJ). The structure of APLNR was resolved
Apelin_receptor
Mammalian protein found in Homo sapiens
The histamine H4 receptor, like the other three histamine receptors, is a member of the G protein-coupled receptor superfamily that in humans is encoded
Histamine_H4_receptor
Protein-coding gene in the species Homo sapiens
The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH)
Follicle-stimulating hormone receptor
Follicle-stimulating_hormone_receptor
There are two known parathyroid hormone receptors in mammals termed PTH1R and PTH2R. These receptors bind parathyroid hormone and are members of the GPCR
Parathyroid_hormone_receptor
Class of receptor proteins that bind histamine
physiological processes. There are four main types of histamine receptors: H1, H2, H3, and H4. H1 receptors are linked to allergic responses, H2 to gastric
Histamine_receptor
CNS stimulant and isomer of amphetamine
either type 1 or type 2, with only the former presenting cataplexy symptoms. Type 1 narcolepsy results from the loss of approximately 70,000 orexin-releasing
Dextroamphetamine
Receptor protein that binds with somatcrinin
The growth-hormone-releasing hormone receptor (GHRHR) is a G-protein-coupled receptor that binds growth hormone-releasing hormone. The GHRHR activates
Growth-hormone-releasing hormone receptor
Growth-hormone-releasing_hormone_receptor
Neuron membrane protein
Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base
Glutamate_receptor
Protein-coding gene in the species Homo sapiens
Hydroxycarboxylic acid receptor 2 (HCA2), also known as GPR109A and niacin receptor 1 (NIACR1), is a protein which in humans is encoded (its formation
Hydroxycarboxylic acid receptor 2
Hydroxycarboxylic_acid_receptor_2
Protein-coding gene in the species Homo sapiens
Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of
Prostaglandin_EP2_receptor
Mammalian protein found in humans
The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ions. It is primarily expressed
Calcium-sensing_receptor
Chemoreceptors expressed in cell membranes of olfactory receptor neurons
Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible
Olfactory_receptor
Protein found in humans
receptor type 2 is a protein that in humans is encoded by the NTSR2 gene. The protein encoded by this gene belongs to the G protein-coupled receptor family
Neurotensin_receptor_2
Type of G-protein coupled receptor
The bombesin receptors are a group of G-protein coupled receptors which bind bombesin. Three bombesin receptors are currently known: BB1, previously known
Bombesin_receptor
Protein-coding gene in the species Homo sapiens
the GCGR gene is associated with diabetes mellitus type 2. Inactivating mutation of glucagon receptor in humans causes resistance to glucagon and is associated
Glucagon_receptor
G protein-coupled receptor
are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation
Endothelin_receptor
Protein-coding gene in the species Homo sapiens
Melanin-concentrating hormone receptor (MCHR) Melanin-concentrating hormone receptor 1 (MCHR1) Melanin-concentrating hormone receptor 2 (MCHR2) Orexin (OX) GRCh38: Ensembl
Melanin-concentrating_hormone
Protein-coding gene in the species Homo sapiens
Prostanoid receptors (see Eicosanoid receptor#Prostenoid receptors). DP2 was found to stimulate the directed movement or chemotaxis of human T-helper type 2 cells
Prostaglandin_DP2_receptor
Class of 33 human protein receptors
Adhesion G protein-coupled receptors (adhesion GPCRs) are a class of 33 human protein receptors with a broad distribution in embryonic and larval cells
Adhesion G protein-coupled receptor
Adhesion_G_protein-coupled_receptor
Class of G protein-coupled receptors
amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a family of G protein-coupled receptors that were discovered
Trace amine-associated receptor
Trace_amine-associated_receptor
Protein-coding gene in the species Homo sapiens
The Muscarinic Acetylcholine receptor M1, also known as the Cholinergic receptor, Muscarinic 1, is a muscarinic receptor that in humans is encoded by
Muscarinic acetylcholine receptor M1
Muscarinic_acetylcholine_receptor_M1
Index of articles associated with the same name
acid receptor 2 (LPAR2; formerly known as EDG4) Lysophosphatidic acid receptor 3 (LPAR3; formerly known as EDG7) Lysophosphatidic acid receptor 4 (LPAR4;
Lysophosphatidic acid receptor
Lysophosphatidic_acid_receptor
G protein-coupled receptor
G protein-coupled receptors (GPCRs) called vasopressin receptors that are classified into the V1 (V1A), V2, and V3 (V1B) receptor subtypes. These three
Vasopressin_receptor
Class of G protein-coupled receptors
dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors. The existence of multiple types of receptors for
Dopamine_receptor
Sleep disorder in children
various areas brain through its interaction with orexin receptors, a type of G protein-coupled receptor. Importantly, the dorsal raphe nucleus, locus coeruleus
Pediatric_narcolepsy
Subtype of Dopamine Receptor
Dopamine receptor D3 (DRD3) is a protein belonging to the dopamine receptor family of G protein-coupled receptors. In humans, it is encoded by the DRD3
Dopamine_receptor_D3
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OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
Boy/Male
Biblical Latin
Strength; rock; sharp.
Surname or Lastname
English (Devon)
English (Devon) : unexplained.
Girl/Female
Danish, German, Swedish
A City in Phoenicia
Surname or Lastname
English (Cornish)
English (Cornish) : habitational name from Trewin in Cornwall.
Boy/Male
Indian, Sanskrit
The Preceptor
Girl/Female
Christian & English(British/American/Australian)
River
Boy/Male
English French
Fiery.
Surname or Lastname
Scottish
Scottish : reduced form of McIntyre.English : variant spelling of Tyer.
Boy/Male
Arabic
Educator; Preceptor
Girl/Female
English
River.
Male
English
English surname transferred to forename use, derived from the Middle English word tye, TYE means "pasture."
Male
Welsh
Welsh form of Celtic Brennus, BRENIN means "king."
Surname or Lastname
English (mainly East Anglia)
English (mainly East Anglia) : topographic name for someone who lived by a common pasture, Middle English tye (Old English tēag).North German : from a short form, Tide, of the personal name Dietrich.
Surname or Lastname
English (Leicestershire)
English (Leicestershire) : of uncertain origin; perhaps variant spelling of Bruin, or alternatively the Irish name (see 2).Irish : Anglicized form of Gaelic Ó Braion ‘descendant of Braon’, a byname meaning ‘moisture’, ‘drop’.
Girl/Female
American, British, English, Jamaican
A River in England; River
Male
English
Variant spelling of English Oran, ORRIN means "little sallow one."
Male
Welsh
Variant spelling of Welsh Owain, OWEIN means "born of yew."
Male
Danish
, a female dog; or, the mad, raging.
Male
Danish
, a female dog; or, the mad, raging.
Surname or Lastname
Irish
Irish : reduced Anglicized form of Gaelic Ó Teimhin ‘descendant of Teimhean’, from teimhean ‘dark’, an adjective from teimhe ‘dusk’, ‘darkness’.English : probably a habitational name for someone from Tyneside in northeast England.
OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
OREXIN RECEPTOR-TYPE-2
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