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The replication factor C, or RFC, is a five-subunit protein complex that is required for DNA replication. The subunits of this heteropentamer are named
Replication_factor_C
Proteine
is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase
RFC1
Biological process
near-perfect fidelity for DNA replication. DNA replication usually begins at specific locations known as origins of replication which are scattered across
DNA_replication
DNA replication in eukaryotic organisms
Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA
Eukaryotic_DNA_replication
Mammalian protein found in Homo sapiens
clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves
Proliferating cell nuclear antigen
Proliferating_cell_nuclear_antigen
Sequence in a genome
The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. Propagation of the
Origin_of_replication
Protein-coding gene in the species Homo sapiens
Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene. The elongation of primed DNA templates by DNA polymerase delta
RFC3
Protein-coding gene in the species Homo sapiens
Replication factor C subunit 4 is a protein that in humans is encoded by the RFC4 gene. The elongation of primed DNA templates by DNA polymerase delta
RFC4
Protein found in humans
replication factor 1) is a protein that in humans is encoded by the CDT1 gene. It is a licensing factor that functions to limit DNA from replicating more
DNA_replication_factor_CDT1
Protein-coding gene in the species Homo sapiens
checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro". Proc. Natl. Acad. Sci. U.S.A. 100 (4): 1633–8
Cell cycle checkpoint protein RAD1
Cell_cycle_checkpoint_protein_RAD1
Protein-coding gene in the species Homo sapiens
Replication factor C subunit 5 is a protein that in humans is encoded by the RFC5 gene. The elongation of primed DNA templates by DNA polymerase delta
RFC5
Protein-coding gene in the species Homo sapiens
Replication factor C subunit 2 is a protein that in humans is encoded by the RFC2 gene. The elongation of primed DNA templates by DNA polymerase delta
RFC2
Topics referred to by the same term
modification for Sid Meier's Civilization IV Regenerative fuel cell Replication factor C, a protein complex Radio frequency choke, a type of choke Reconstruction
RFC
Class of enzymes
presence of PCNA (proliferating cell nuclear antigen), RFC (replication factor C) and RPA (replication protein A). Either DNA polymerase epsilon or DNA polymerase
DNA_polymerase_epsilon
Protein-coding gene in the species Homo sapiens
consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA
HUS1
British biomedical researcher
within the four small subunits of human replication factor C required for complex formation and DNA replication". The Journal of Biological Chemistry.
Frank_Uhlmann
Enzyme complex
proliferating cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor C, through its role as the clamp loader for PCNA (which involves catalysing
DNA_polymerase_delta
never separate after replication. Another significant tie between DNA replication and cohesion pathways is through Replication Factor C (RFC). This complex
Establishment of sister chromatid cohesion
Establishment_of_sister_chromatid_cohesion
DNA region replicating from a single origin
replicon model for replication initiation. According to the replicon model, two components control replication initiation: the replicator and the initiator
Replicon_(genetics)
Medical condition
of CANVAS cases have been found to be caused by a mutation in the replication factor C subunit 1 gene. CANVAS is typically inherited in an autosomal recessive
Cerebellar ataxia, neuropathy, vestibular areflexia syndrome
Cerebellar_ataxia,_neuropathy,_vestibular_areflexia_syndrome
Protein-coding gene in humans
is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon". Nucleic Acids Res
POLE_(gene)
Sharing information to ensure consistency in computing
theorem. Replication in computing can refer to: Data replication, where the same data is stored on multiple storage devices Computation replication, where
Replication_(computing)
Protein-coding gene in the species Homo sapiens
This gene encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric
CTF8
Protein-coding gene in the species Homo sapiens
Tsurimoto T, Kamiya K (2007). "Dynamics of human replication factors in the elongation phase of DNA replication". Nucleic Acids Res. 35 (20): 6904–16. doi:10
POLD3
Protein-coding gene in humans
"Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway". Molecular
CHTF18
Observed inability to reproduce scientific studies
category, replication, involves repeating an experiment or study with new, independent data to verify the original conclusions. Replication has been called
Replication_crisis
DNA repair mechanism
helps reduce exposed single stranded DNA during the repair process. Replication factor C (RFC) loads the Proliferating Cell Nuclear Antigen (PCNA) onto the
Nucleotide_excision_repair
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
PMID 25200073. Delestienne N, Wauquier C, Soin R, Dierick JF, Gueydan C, Kruys V (June 2010). "The splicing factor ASF/SF2 is associated with
Stress_granule
Protein-coding gene in the species Homo sapiens
is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase ε". Nucleic Acids Res. 31 (19):
POLE2
Protein family
amino acids. The eukaryotic equivalent to the DNA clamp loader is replication factor C, with the subunits RFC1, RFC2, RFC3, RFC4, and RFC5. The domain is
DNA polymerase III subunit gamma/tau
DNA_polymerase_III_subunit_gamma/tau
Protein-coding gene in the species Homo sapiens
Lindsey-Boltz LA, Sancar A (May 2002). "Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low
RAD9A
Protein-coding gene in the species Homo sapiens
(September 2002). "A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase". Molecular and Cellular Biology
BRD4
Protein-coding gene in the species Homo sapiens
critical components of the replication machinery, such as proliferating cell nuclear antigen (PCNA) and replication factor C subunits RFC4 and RFC5, forming
LRDD
Protein
domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells". The EMBO
P21
Protein-coding gene in the species Homo sapiens
dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. GRCh38: Ensembl release 89: ENSG00000115350 – Ensembl
POLE4
Type of repeated DNA sequence
work to promote binding of replication machinery, replication can be halted in this form. Another factor used to stop replication is known as dimerization
Iteron
Protein-coding gene in the species Homo sapiens
Yokomori K, Hurwitz J (Sep 2003). "The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating
DCC1
Protein-coding gene in the species Homo sapiens
response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC) and can form a complex with RFCs. This protein binds to chromatin
RAD17
Molecular complex
bidirectional replication. The two replisomes continue replication at both forks in the middle of the cell. Finally, as the termination site replicates, the two
Replisome
Protein-coding gene in the species Homo sapiens
containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies
WRNIP1
Protein-coding gene in the species Homo sapiens
the PCNA (proliferating cell nuclear antigen) in conjunction with replication factor C (RFC) that acts as a stabilizer and places newly synthesized nucleotides
MUTYH
Protein-coding gene in the species Homo sapiens
function in proofreading to ensure replication accuracy during DNA synthesis, and in a number of types of replication-linked DNA repair following DNA damage
POLD1
Protein
chromosome called the replicator to start DNA replication. It is a replication initiation factor which promotes the unwinding of DNA at oriC. The DnaA proteins
DnaA
transcription factor MeSH D12.776.260.108.500.061.625 – oncogene protein v-maf MeSH D12.776.260.108.500.061.750 – proto-oncogene proteins c-maf MeSH D12
List of MeSH codes (D12.776.260)
List_of_MeSH_codes_(D12.776.260)
Family of viruses
be packaged and circularizes during DNA replication. The phycodnaviruses have compact genomes for replication efficiency with approximately one gene per
Phycodnaviridae
Protein domain
in DNA replication. The protein negatively regulates the initiation of DNA replication at the origin of replication, in Escherichia coli, OriC. Additionally
SeqA_protein
Protein complex
interacts with PCNA to attach to the replication fork. The CAF-1 complex adds the histones to the DNA ahead of the replication fork. A mutation in p150 that
Chromatin_assembly_factor_1
Process of copying a segment of DNA into RNA
are seen in DNA replication. This also removes the need for an RNA primer to initiate RNA synthesis, as is the case in DNA replication. The non-template
Transcription_(biology)
Undesirable occurrence in eukaryotic cells
successive generations. Replication of DNA always begins at an origin of replication. In yeast, the origins contain autonomously replicating sequences (ARS),
DNA_re-replication
Protein complex formed during initiation of DNA replication
A pre-replication complex (pre-RC) is a protein complex that forms at the origin of replication during the initiation step of DNA replication. Formation
Pre-replication_complex
Personality model consisting of five broad dimensions
psychology and psychometrics, the Big Five personality trait model or five-factor model (FFM), sometimes called by the mnemonic acronym OCEAN or CANOE, is
Big_Five_personality_traits
Investment approach in stock returns
Factor investing is an investment approach that targets measurable characteristics of securities, known as factors, which help explain differences in risk
Factor_investing
Experimental design in statistics
error. When the number of factors is large (typically more than about 5 factors, but this does vary by application), replication of the design can become
Factorial_experiment
Protein found in humans
Insulin-like growth factor 1 (IGF1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in
Insulin-like_growth_factor_1
DNA replication in prokaryotes
bacteria show many similarities. Replication is bi-directional and originates at a single origin of replication (OriC). It consists of three steps: Initiation
Prokaryotic_DNA_replication
Protein-coding gene in the species Homo sapiens
"The HeLa Pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication". Molecular and
PURA
Formation of biological viruses during the infection process
proteins and nucleic acids. Virus replication occurs in seven stages: Attachment Entry (penetration) Uncoating Replication Assembly Maturation Release (liberation
Viral_replication
Type of chromosome
bacteria chromosome replication is best understood in the well-studied bacteria Escherichia coli and Bacillus subtilis. Chromosome replication proceeds in three
Circular_chromosome
Rolling hairpin replication (RHR) is a unidirectional, strand displacement form of DNA replication used by parvoviruses, a group of viruses that constitute
Rolling_hairpin_replication
Type of DNA molecule
DNA viruses employ recombination-dependent replication to produce concatemers. In this mechanism, replication is initiated at multiple sites, followed by
Concatemer
DNA synthesis technique
Rolling circle replication (RCR) is a process of unidirectional nucleic acid replication that can rapidly synthesize multiple copies of circular molecules
Rolling_circle_replication
rate of DNA replication during S phase of the cell cycle is dependent on the processivity of the DNA polymerases performing the replication. DNA clamp
Processivity
Natural regrowth of damaged liver tissue
various growth factors, including two factors that play a major role in liver regeneration, EGFR (epidermal growth factor receptor) and c-Met. During this
Liver_regeneration
Catalase-positive bacterium
bacterial chromosome replication. Replication of the single circular chromosome initiates at a single locus, the origin (oriC). Replication proceeds bidirectionally
Bacillus_subtilis
Protein-coding gene in the species Homo sapiens
Carius B, Haque SJ, et al. (1999). "The DNA-binding subunit p140 of replication factor C is upregulated in cycling cells and associates with G1 phase cell
TCEAL1
Gene on human chromosome 5
upregulation of Replication Factor C". Cell Death & Disease. 12 (1) 12. doi:10.1038/s41419-020-03348-2. PMC 7791038. PMID 33414468. Wang P, Sun J, Sun C, Zhao H
BTF3
Second subphase of interphase
clamps. Loading of these factors completes the active replication fork and initiates synthesis of new DNA. Complete replication fork assembly and activation
S_phase
Protein-coding gene in the species Homo sapiens
PMID 12419806. Anderson LA, Perkins ND (August 2002). "The large subunit of replication factor C interacts with the histone deacetylase, HDAC1". The Journal of Biological
HDAC1
Cis-acting replication elements (cre) bring together the 5′ and 3′ ends during replication of positive-sense single-stranded RNA viruses (for example
Cis-acting replication element
Cis-acting_replication_element
Stage in cell cycle
phosphorylate several factors on the replication complex promoting DNA replication by causing inhibitory proteins to fall off of replication complexes or through
G1/S_transition
HIV-2 and SIV protein
enhances viral replication by inhibiting host antiviral factors. Vpx enhances HIV-2 replication in humans by counteracting the host factor SAMHD1. SAMHD1
Vpx
DNA replication licensing factor MCM6 is a protein that in humans is encoded by the MCM6 gene. MCM6 is one of the highly conserved mini-chromosome maintenance
MCM6
Protein-coding gene in humans
of the two predicted promoters binds transcription factors. There are many transcription factors predicted to bind to the promoter region of FAM216A
FAM216A
Protein-coding gene in the species Homo sapiens
with ERCC1, Replication protein A1 and XAB2. XPA4-97, the N-terminus, has binding regions for Replication protein A 34 and ERCC1. The C-terminal domain
XPA
Enzyme found in humans
effective in replication arrest recovery. WRN may also be important in telomere maintenance and replication, especially the replication of the G-rich
Werner_syndrome_helicase
Protein-coding gene in the species Homo sapiens
2003). "Regulation of RelA (p65) function by the large subunit of replication factor C". Molecular and Cellular Biology. 23 (2): 721–732. doi:10.1128/MCB
RELA
Protein-coding gene in the species Homo sapiens
and is necessary for origin licensing and DNA replication. KAT7 associates with origins of replication during G1 phase of the cell cycle through complexing
KAT7_(gene)
Enzymes that catalyze DNA formation
collapse of replication forks where replication polymerases have stalled. Telomerase is a ribonucleoprotein which functions to replicate ends of linear
DNA_polymerase
Protein-coding gene in humans
Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. The human TERF1 gene is located in the chromosome 8 at 73,921
Telomeric repeat-binding factor 1
Telomeric_repeat-binding_factor_1
RNA family
initiation factor for DNA replication. Mutant human Y RNAs lacking the conserved binding site for Ro60 protein still support DNA replication, indicating
Y_RNA
Nuclear protein inhibiting DNA replication
negative regulator of DNA replication. In many cancer cell lines, inhibition of geminin by RNA interference results in re-replication of portions of the genome
Geminin
Protein-coding gene in humans
DNA replication licensing factor MCM2 is a protein that in humans is encoded by the MCM2 gene. The protein encoded by this gene is one of the highly conserved
MCM2
Protein family
defective in the regulation of DNA replication initiation. The rationale behind this screen was that if replication origins were regulated in a manner
Minichromosome_maintenance
Protein-coding gene in the species Homo sapiens
MEN1, RPA3, Replication protein A1, STAT3, TP53BP1 and Uracil-DNA glycosylase. Single-stranded binding protein Replication protein A Replication protein A1
Replication_protein_A2
Protein-coding gene in the species Homo sapiens
Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene. ENSG00000022277 GRCh38: Ensembl release 89: ENSG00000137815,
RTFDC1
Protein-coding gene in the species Homo sapiens
excision repair Single-stranded binding protein Replication protein A Replication protein A1 Replication protein A2 GRCh38: Ensembl release 89: ENSG00000106399
Replication_protein_A3
Form factor for desktop computers and motherboards
Small form factor (SFF) is a classification of desktop computers and for some of their components, chassis and motherboard, to indicate that they are designed
Small_form_factor_PC
Protein-coding gene in humans
DNA replication licensing factor MCM3 is a protein that in humans is encoded by the MCM3 gene. The protein encoded by this gene is one of the highly conserved
MCM3
Family of viruses
complete their full replication cycle within the host cells cytoplasm. Replication of the poxvirus involves several stages. The replication can be divided
Poxviridae
Unusual DNA structures Conflicts between replication and transcription Insufficiency of essential replication factors Common fragile sites Overexpression or
DNA_replication_stress
Protein-coding gene in the species Homo sapiens
mitochondrial transcription factor that is a key activator of mitochondrial transcription and participates in mitochondrial genome replication. TFAM binds mitochondrial
TFAM
DNA located in cellular organelles called chloroplasts
dehydrogenase ribosomal proteins tRNA replication origin regions tRNA small RNA ribosomal protein replication origin regions ribosomal RNA tRNAs ribosomal
Plastid_DNA
Class of viruses in the Baltimore classification
after infection serve genome replication functions; they recruit the positive-strand viral genome to viral replication complexes formed in association
Positive-strand_RNA_virus
Gene that can be expressed in response to stimulation by interferon
act as an initial response to pathogen invasion, slowing down viral replication and increasing expression of immune signaling complexes. There are three
Interferon-stimulated_gene
Species of virus
the proteins needed for replication. Each virion sets up a region in the cytoplasm, called a 'viral factory' where DNA replication, transcription, and translation
Molluscum_contagiosum_virus
Protein-coding gene in humans
DNA replication licensing factor MCM7 is a protein that in humans is encoded by the MCM7 gene. The protein encoded by this gene is one of the highly conserved
MCM7
Species of flavivirus causing West Nile fever
without breaking viral replication, and are large enough to manipulate CpG and UpA frequencies, thereby preserving viral replication competence. Once WNV
West_Nile_virus
Proteins that bind with DNA
ISSN 0305-1048. PMC 4824100. PMID 26762975. Iftode C, Daniely Y, Borowiec J (1999). "Replication protein A (RPA): the eukaryotic SSB". Crit Rev Biochem
DNA-binding_protein
Concept in financial mathematics
Black–Scholes model, which requires dynamic replication and continual transaction in the underlying. Replication assumes one can enter into derivative transactions
Put–call_parity
Free and open-source database management system
in CQL 3.0: CREATE KEYSPACE MyKeySpace WITH REPLICATION = { 'class' : 'SimpleStrategy', 'replication_factor' : 3 }; USE MyKeySpace; CREATE COLUMNFAMILY
Apache_Cassandra
REPLICATION FACTOR-C
REPLICATION FACTOR-C
Male
English
Roman Latin name VICTOR means "conqueror."Â
Boy/Male
Hindu, Indian
Application
Boy/Male
American, Australian, British, Chinese, Christian, Danish, Dutch, English, French, German, Greek, Italian, Latin, Portuguese, Shakespearean, Spanish
Steadfast; Anchor; Holds Fast; Star; Coined from Esther Vanhomrigh; Tenacious; Defend; Hold Fast; Coined from Esther Vanho
Boy/Male
American, British, Christian, Danish, Dutch, English, Finnish, French, German, Greek, Hindu, Indian, Irish, Jamaican, Latin, Romanian, Slovenia, Spanish, Swedish, Swiss, Tamil, Ukrainian
Victorious; Conqueror; Winner; Champion; One who Conquers; Victory
Surname or Lastname
English
English : habitational name from places called Caistor, in Lincolnshire and Norfolk, Caister in Norfolk, or Castor in Cambridgeshire, all named with Old English cæster ‘Roman fort or town’.
Male
Spanish
Spanish name derived from Latin Pastor, PASTOR means "shepherd." St. Pastor was a 9-year-old boy who along with his 13-year-old brother, Justus, was martyred at Alcalá de Henares in the early 4th century.
Boy/Male
English American
Doctor; teacher.
Male
Arthurian
, sir Hector de Maris; (defender).
Boy/Male
Indian
Realisation
Male
Greek
(ΚάστωÏ) Greek name KASTOR means "beaver." In mythology, Castor/Kastor and Pollux/Polydeukes ("very sweet") are the twin sons of Leda and are known as the Gemini twins.
Male
English
 Anglicized form of Scottish Gaelic Eachann, HECTOR means "brown horse." Compare with another form of Hector.
Male
French
 French and German name derived from Occitan astor, ASTOR means "goshawk," itself from Latin acceptor, a variant of accipiter, meaning "hawk." It was originally a derogatory term for men with hawk-like, predatory characteristics.
Surname or Lastname
English (chiefly Northamptonshire)
English (chiefly Northamptonshire) : probably from the obsolete slang term facer, denoting a braggart or bully. The earliest citation for this term in OED is c. 1515.Americanized spelling of German Feeser.
Surname or Lastname
French and Italian
French and Italian : occupational name from French, northern Italian sartor ‘tailor’ (Latin sartor).English : topographic name denoting someone who lived on land which had been cleared for cultivation, Old French assart, essart ‘woodland cleared for cultivation’ + the habitational suffix -er.
Male
Icelandic
Perhaps a modern form of Icelandic Fylkir, FALKOR means "people, tribe."Â
Male
Spanish
Spanish form of Roman Latin Victor, VÃCTOR means "conqueror."
Girl/Female
Hindu, Indian
Realization
Surname or Lastname
English, Portuguese, Galician, Spanish, Catalan, and French
English, Portuguese, Galician, Spanish, Catalan, and French : occupational name for a shepherd, Anglo-Norman French pastre (oblique case pastour), Portuguese, Galician, Spanish, Catalan, pastor ‘shepherd’, from Latin pastor, an agent derivative of pascere ‘to graze’. The religious sense of a spiritual leader was rare in the Middle Ages, and insofar as it occurs at all it seems always to be a conscious metaphor; it is unlikely, therefore, that this sense lies behind any examples of the surname.German and Dutch : humanistic name, a Latinized form of various vernacular names meaning ‘shepherd’, for example Hirt or Schäfer (see Schafer).Americanized spelling of Hungarian Pásztor, an occupational name from pásztor ‘shepherd’.
Surname or Lastname
English
English : variant spelling of Canter.German and Jewish (Ashkenazic) : variant spelling of Kantor.French (Picardy) : learned form of chantre ‘singer’. Compare Canter 1.
Male
Spanish
Spanish form of Latin Hector, H�CTOR means "defend; hold fast."
REPLICATION FACTOR-C
REPLICATION FACTOR-C
Surname or Lastname
English (eastern counties)
English (eastern counties) : unexplained.
Boy/Male
Arabic, Indian, Muslim, Swedish
Kind; Willing and Wiseman; Noble Man
Boy/Male
Arabic, Muslim
Handsome; Comely
Male
Egyptian
, a priest of Amen Ra.
Surname or Lastname
English
English : from the Middle English and Old English personal name Brūning, originally a patronymic from the byname Brūn (see Brown).This name was brought independently to North America from England by numerous different bearers from the 17th century onward. William Browning was one of the free planters who assented to the ‘Fundamental Agreement’ of the New Haven Colony on June 4, 1639.
Boy/Male
Tamil
Female mountain goat
Surname or Lastname
English (East Anglia)
English (East Anglia) : metonymic occupational name for a fisherman or fish seller, or a nickname for someone supposedly resembling a fish in some way, from Old Norse fiskr ‘fish’ (cognate with Old English fisc).
Girl/Female
German
Little and Womanly; Female Version of Charles
Female
Finnish
Finnish pet form of Dutch/Finnish Marja, MARJUKKA means "obstinacy, rebelliousness" or "their rebellion."
Male
English
Another Anglicized form of Hebrew Yehuwdah, JUDE means "praised." In the bible, this is the name of the brother of James.Â
REPLICATION FACTOR-C
REPLICATION FACTOR-C
REPLICATION FACTOR-C
REPLICATION FACTOR-C
REPLICATION FACTOR-C
n.
The act of directing or referring something to a particular case, to discover or illustrate agreement or disagreement, fitness, or correspondence; as, I make the remark, and leave you to make the application; the application of a theory.
n.
One who transacts business for another; an agent; a substitute; especially, a mercantile agent who buys and sells goods and transacts business for others in commission; a commission merchant or consignee. He may be a home factor or a foreign factor. He may buy and sell in his own name, and he is intrusted with the possession and control of the goods; and in these respects he differs from a broker.
n.
See Faitour.
n.
The capacity of being practically applied or used; relevancy; as, a rule of general application.
n.
The act of fixing the mind or closely applying one's self; assiduous effort; close attention; as, to injure the health by application to study.
n.
The body of factors in any place; as, a chaplain to a British factory.
n.
The act or process of dividing by natural growth or spontaneous action; as, the duplication of cartilage cells.
adv.
In fact; by the act or fact.
pl.
of Factum
n.
A building, or collection of buildings, appropriated to the manufacture of goods; the place where workmen are employed in fabricating goods, wares, or utensils; a manufactory; as, a cotton factory.
n.
A request; a document containing a request; as, his application was placed on file.
n.
A house or place where factors, or commercial agents, reside, to transact business for their employers.
n.
The act of making request of soliciting; as, an application for an office; he made application to a court of chancery.
n.
Same as Radius vector.
v. t.
To resolve (a quantity) into its factors.
v. t.
To confer a doctorate upon; to make a doctor.
n.
The act of applying or laying on, in a literal sense; as, the application of emollients to a diseased limb.
n.
The reply of the plaintiff, in matters of fact, to the defendant's plea.
imp. & p. p.
of Factor