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Nucleotide or amino-acid sequence pattern
In biology, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function
Sequence_motif
Bioinformatic graphic
aligned protein or DNA/RNA sequences and conveys information about the conservation of each position of a sequence motif or sequence alignment . However, a
Sequence_logo
Succession of nucleotides in a nucleic acid
Frequently the primary structure encodes motifs that are of functional importance. Some examples of sequence motifs are: the C/D and H/ACA boxes of snoRNAs
Nucleic_acid_sequence
ATP-binding protein sequence motifs
The Walker A and Walker B motifs are protein sequence motifs, known to have highly conserved three-dimensional structures. These were first reported in
Walker_motifs
Topics referred to by the same term
creates a larger work Motif (visual arts), a repeated theme or pattern Sequence motif, a sequence pattern of nucleotides in a DNA sequence or amino acids in
Motif
Type of common three-dimensional structure in chain-like biological molecules
a sequence motif; it can be represented by different and completely unrelated sequences in different proteins or RNA. Depending upon the sequence and
Structural_motif
Type of amino acid sequence
A nuclear localization sequence, or signal (NLS) is an amino acid sequence motif that 'tags' a protein for import into the cell nucleus by nuclear transport
Nuclear_localization_sequence
Conserved RNA structure
protein-coding genes. Instances of the aspS RNA motif are often located nearby to the predicted Shine-Dalgarno sequence of the downstream gene. This arrangement
AspS_RNA_motif
Biomolecule consisting of chains of amino acid residues
acid sequences within proteins often act as recognition sites for other proteins. For instance, SH3 domains typically bind to short PxxP motifs (i.e.
Protein
Most common variant of a genetic sequence across samples
compared to each other and similar sequence motifs are calculated. Such information is important when considering sequence-dependent enzymes such as RNA polymerase
Consensus_sequence
Tools for the analysis of biomolecules
MEME suite is a collection of tools for the discovery and analysis of sequence motifs. It was developed by Timothy Bailey in the Department of Pharmacology
MEME_suite
Class of peptides
translation of a protein in a biological cell. These peptides share a core sequence motif of DxExNPGP, and are found in a wide range of viral families. 2A peptides
2A_peptides
Protein family
The IQ calmodulin-binding motif is an amino acid sequence motif containing the following sequence: [FILV]Qxxx[RK]Gxxx[RK]xx[FILVWY] The term "IQ" refers
IQ_calmodulin-binding_motif
Protein family
Dispanins in eukaryotes and bacteria have high sequence similarities and share several conserved sequence motifs indication a common evolutionary ancestor
Dispanin
Alignment of more than two molecular sequences
Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or
Multiple_sequence_alignment
Target peptide sequence
target peptide sequence motif in mammals and plants located on the C-terminal end of the amino acid structure of a protein. The KDEL sequence prevents a protein
KDEL_(amino_acid_sequence)
DNA sequence motif
In molecular biology, an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate
Exonic_splicing_enhancer
performed or conceived. Motif description: Depicts the most important elements, the essential aspects of the movement sequence. Motif description is often
Motif_description
American mathematician and statistician
several early software on biological sequence motif discovery.: MACAW, Gibbs Motif Sampler, BioProspector, Motif regressor, MDScan, Tmod; on genetic data
Jun_S._Liu
Protein family
The WH2 motif or WH2 domain is an evolutionarily conserved sequence motif contained in proteins. It is found in WASP proteins which control actin polymerisation
WH2_motif
RG/RGG sequence motiff
arginine-glycine or arginine-glycine-glycine (RG/RGG) motif is a repeating amino acid sequence motif commonly found in RNA-binding proteins (RBPs). RGG regions
RG/RGG_motif
Protein domain
The Kelch motif is a region of protein sequence found widely in proteins from bacteria and eukaryotes. This sequence motif is composed of about 50 amino
Kelch_motif
maximizations for Motif Elicitation (MEME) is a tool for discovering motifs in a group of related DNA or protein sequences. A motif is a sequence pattern that
Multiple EM for Motif Elicitation
Multiple_EM_for_Motif_Elicitation
Process in bioinformatics that identifies equivalent sites within molecular sequences
interpreted as a rough measure of how conserved a particular region or sequence motif is among lineages. The absence of substitutions, or the presence of
Sequence_alignment
RNA motif is a description of a group of RNAs that have a related structure. RNA motifs consist of a pattern of features within the primary sequence and
RNA_motif
Three-dimensional arrangement of atoms in an amino acid-chain molecule
unit. The structural and sequence motifs refer to short segments of protein three-dimensional structure or amino acid sequence that were found in a large
Protein_structure
In molecular biology short linear motifs (SLiMs), linear motifs or minimotifs are short stretches of protein sequence that mediate protein–protein interaction
Short_linear_motif
Protein domain
domain was discovered in 1999 and named after a conserved sequence motif found in its protein sequence. Roth and colleagues showed that the yeast Akr1p protein
DHHC_domain
sequence motifs or degrons found in its substrates. These degrons can be split into three major groups: destruction boxes, KEN boxes, and ABBA motifs
Motifs_targeted_by_APC/C
Protein sequence motif
A FFAT motif (FFAT being an acronym for two phenylalanines (FF) in an acidic tract) is a protein sequence motif of six defined amino acids plus neighbouring
FFAT_motif
Regions of DNA capable of binding to biomolecules
for sequence motif discovery. These methods rely on the hypothesis that a set of sequences share a binding motif for functional reasons. Binding motif discovery
DNA_binding_site
MochiView (Motif and ChIP Viewer) is software that integrates a genome browser and tools for data and Sequence motif visualization and analysis. The software
MochiView
RNA element found in Pospiviroids such as potato spindle tuber viroid (PSTVd)
Pospiviroid RY motif stem loop is an RNA element found in Pospiviroids such as potato spindle tuber viroid (PSTVd). The RY nucleotide sequence motif (5'-ACAGG
Pospiviroid RY motif stem loop
Pospiviroid_RY_motif_stem_loop
Protein fold
conserved Rossmann fold motif. In 1989, Israel Hanukoglu from the Weizmann Institute of Science discovered that the consensus sequence for NADP+ binding site
Rossmann_fold
An ATP-binding motif is a 250-residue sequence within an ATP-binding protein’s primary structure. The binding motif is associated with a protein’s structure
ATP-binding_motif
Type of motif in immunology
represent any immunoreceptor tyrosine-based inhibitory-like sequence motif, with the consensus sequence I/V/L/SxYxxL/V, found in a kinase and regulating its
Kinase tyrosine-based inhibitory motif
Kinase_tyrosine-based_inhibitory_motif
Series of music workstations
Motif (stylized in all-uppercase MOTIF) is a series of music workstation synthesizers, first released by Yamaha Corporation in August 2001. The Motif
Yamaha_Motif
Database of protein domains, families and functional sites
similarities. PROSITE offers tools for protein sequence analysis and motif detection (see sequence motif, PROSITE patterns). It is part of the ExPASy proteomics
PROSITE
In genetics and biochemistry, determining the structure of an unbranched biopolymer
genome sequencing Genetic code Pathogenomics RNA-Seq MicroRNA sequencing Sequence motif Wheeler, David A.; Srinivasan, Maithreyan; Egholm, Michael; Shen, Yufeng;
Sequencing
list of sequence alignment software is a compilation of software tools and web portals used in pairwise sequence alignment and multiple sequence alignment
List of sequence alignment software
List_of_sequence_alignment_software
Use of bioinformatic methods to correlate proteins with biofunctions
domains, families and functional sites') can be searched using a query sequence. Motifs can, for example, be used to predict subcellular localization of a
Protein_function_prediction
Repetitive DNA with distinct base composition
A fifth divergent domain in the RU sequence was characterized by variations of a symmetrical DNA sequence motif of alternating purines and pyrimidines
Satellite_DNA
Protein domain
receptors. The LysM domain is named after the Lysin Motif which was the original name given to the sequence motif identified in bacterial proteins. The region
LysM_domain
Statistical Markov model
of bio-sequences Time series analysis Activity recognition Protein folding Sequence classification Metamorphic virus detection Sequence motif discovery
Hidden_Markov_model
for DNA sequence analysis that is free and open to all users (without login requirement). For locating matches to a user-specified sequence motif for a
Phyloscan
22704. PMC 7610952. PMID 20310069. Suzuki, M (1989). "SPXX, a frequent sequence motif in gene regulatory proteins". Journal of Molecular Biology. 207 (1):
ST_motif
Small structural protein motif found mostly in transcriptional proteins
acid sequences of varying lengths. Zinc fingers often bind to a sequence of DNA known as the GC box. The modular nature of the zinc finger motif allows
Zinc_finger
Family of RNA-binding proteins
1995, comparisons between the various LSm homologs identified two sequence motifs, 32 nucleic acids long (14 amino acids), that were very similar in
LSm
Protein family
proteasomal degradation, and cell cycle regulation. UBA domains have a common sequence motif of approximately 45 amino acid residues. They fold into three-helix
UBA_protein_domain
Topics referred to by the same term
Moldovan political party (founded 2013) Pentatricopeptide repeat, a sequence motif in genetics Peste des petits ruminants, or ovine rinderpest, a disease
PPR
Protein-coding gene in the species Homo sapiens
National Library of Medicine. "Entrez Gene: Family with sequence similarity 19 member A4, C-C motif chemokine like". Retrieved 2017-12-09. Oguri M, Kato
Chemokine-like_protein_TAFA-4
Protein family
In molecular biology, the Ubiquitin-Interacting Motif (UIM), or 'LALAL-motif', is a sequence motif of about 20 amino acid residues, which was first described
Ubiquitin-interacting_motif
Protein structural motif
The beta sheet (β-sheet, also β-pleated sheet) is a common motif of the regular protein secondary structure. Beta sheets consist of beta strands (β-strands)
Beta_sheet
Protein domain
by X-ray crystallography by Das and colleagues showed that the TPR sequence motif was composed of a pair of antiparallel alpha helices. The PP5 structure
Tetratricopeptide_repeat
Cytosine-rich quadruplex DNA structure
structure, i-motif DNA stability is dependent on the nature of the sequence, temperature, and ionic strength. The structural stability of i-motif DNA is mainly
I-motif_DNA
Protein domain
alpha helix 1, alpha helix 2 the GXXG loop (contains a highly conserved sequence motif) and the variable loop. The binding cleft is hydrophobic in nature with
KH_domain
DNA sequence that binds activators to increase the likelihood of gene transcription
member of the dimer anchored to its binding motif on the enhancer and the other member anchored to its binding motif on the promoter (represented by the red
Enhancer_(genetics)
Class of enzymes
structural sequence. A 2015 crystallography experiment showed that E. coli Dam methylase was able to bind non-GATC DNA with the same sequence of motifs discussed;
DNA_adenine_methylase
Proto-oncogene derived from polyomavirus SV40
within the Leu – x – Cys – x – Glu sequence, nor in the positions immediately flanking this sequence. The pRb-binding motif and negatively charged region match
SV40_large_T_antigen
Class of enzymes
plants. All members of this class of phytase share a common active site sequence motif (Arg-His-Gly-X-Arg-X-Pro) and have a two-step mechanism that hydrolyzes
Phytase
Restatement of a musical passage
In music, a sequence is the restatement of a motif or longer melodic (or harmonic) passage at a higher or lower pitch in the same voice. It is one of the
Sequence_(music)
Protein family
N-terminal PDZ domain, a centrally positioned sequence motif termed ASD1 (Apx/Shrm Domain 1) and a C-terminal motif termed ASD2. Shrm2 and Shrm3 contain all
Shroom_protein_family
Protein family
binding specificities. There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding
RING_finger_domain
Type of biological prediction
site of the protein. Examples of sequence motif databases are the Prosite catalog and the Stanford Motifs Database. Motif (structural context) a combination
Protein_structure_prediction
Protein family
autophagosome complex. It carries a highly characteristic conserved FLKF sequence motif. GRCh38: Ensembl release 89: ENSG00000144848 – Ensembl, May 2017 GRCm38:
ATG3
Protein domain
Schellman loop at their N-terminus. The ankyrin-repeat sequence motif has been studied using multiple sequence alignment to determine conserved amino acid residues
Ankyrin_repeat
DNA located in mitochondria
within GC-skewed regions and in the close vicinity of the degenerate sequence motif YMMYMNNMMHM. Unlike nuclear DNA, which is inherited from both parents
Mitochondrial_DNA
Region within a prokaryotic cell containing genetic material
structural motif regardless of the sequence, IHF preferentially binds to a specific DNA sequence even though the specificity arises through the sequence-dependent
Nucleoid
Protein family
domain (pp-binding). It has been shown that mutations in the HHXXXDG sequence motif in this domain abolish activity suggesting this is part of the active
Condensation_domain
SELEX has been used to show that Hfq-binding RNAs are enriched in the sequence motif 5'-AAYAAYAA-3'. Hfq was also found to act on ribosome biogenesis in
Hfq_protein
Similar DNA, RNA or protein sequences within genomes or among species
conserved sequences are identical or similar sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences), or within
Conserved_sequence
Short recurring musical phrase
In music, a motif (/moʊˈtiːf/ ) or motive is a short musical idea, salient recurring figure, musical fragment, or succession of notes that has some special
Motif_(music)
Nucleic acid motif in molecular biology
The Kozak consensus sequence (Kozak consensus or Kozak sequence) is a nucleic acid motif that functions as the protein translation initiation site in most
Kozak_consensus_sequence
Structure in molecular biology
computationally predicted from DNA or RNA sequence motifs, but their actual structures can be quite varied within and between the motifs, which can number over 100,000
G-quadruplex
Region of DNA encouraging transcription
dominant Cs and As on one side and Gs and Ts on the other. A motif with the consensus sequence of TCTCGCGAGA, also called the CGCG element, was recently
Promoter_(genetics)
Proteins that substitute in eukaryotes
characterized. H2A.X is the most common H2A variant, with the defining sequence motif 'SQ(E/D)Φ' (where Φ-represents a hydrophobic residue, usually Tyr in
Histone_variants
James Bond signature device
James Chapman suggests that the sequence is a significant part of the James Bond mythos because it "foregrounds the motif of looking, which is central to
Gun_barrel_sequence
Protein-coding gene in the species Homo sapiens
extracellular environment. Biochemical studies have shown that a conserved sequence motif D-Y-L-S-F at the C-terminus, as well as the overall length of the C-terminal
PEN-2
Synthetic DNA transposon for vertebrate genetic modification
DNA-binding domain consists of two paired sequences, which are homologous to sequence motifs found in certain transcription factors. The paired subdomains in SB
Sleeping Beauty transposon system
Sleeping_Beauty_transposon_system
Type of protein domain
cofactors. This histidine is embedded in a DXHXXG sequence, the most conserved primary sequence motif of the domain. Proteins containing the cobalamin-binding
Vitamin_B12-binding_domain
Protein family
The pentatricopeptide repeat (PPR) is a 35-amino acid sequence motif. Pentatricopeptide-repeat-containing proteins are a family of proteins commonly found
Pentatricopeptide_repeat
appear to interact with the sequence. The kinesins KIF17 is implicated in transporting the CNGB1 protein which has a RVxP motif into human cilia, as is Rab8a
RVxP_motif
Convention where symbols represent concepts
delimiters. Nucleic acid notation Systems Biology Graphical Notation (SBGN) Sequence motif pattern-description notations Cytogenetic notation Energy Systems Language
Notation_system
Protein family
The MADS box is a conserved sequence motif. The genes which contain this motif are called the MADS-box gene family. The MADS box encodes the DNA-binding
MADS-box
Protein-coding gene in the species Homo sapiens
contains a C-(X)2-C motif (CLLC), which is mostly present in metal-binding proteins and oxidoreductases. A sorting-signal sequence motif, YXXphi, is also
SLC46A3
Protein-coding gene in the species Homo sapiens
organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists
LSM5
or similar sequence motifs. These periodic sequences are generated by internal duplications in both coding and non-coding genomic sequences. Repetitive
Protein_tandem_repeats
a 15-base-pair palindromic sequence of the TetA operator. These domains mainly consist of a helix-turn-helix (HTH) motif that is common in TetR protein
TetR
Musical composition by Ludwig van Beethoven
"short-short-short-long" motif, often characterized as "fate knocking at the door", the Schicksals-Motiv (fate motif). Sometimes this motif is remembered as "da-da-da-dum"
Symphony_No._5_(Beethoven)
Protein domain
domain in their N-terminal region, which seems to bind a different sequence motif present in the C-terminal part of RanGTP protein. Tertiary structure
WH1_domain
DNA structure
tandem intramolecular triplexes of the H-DNA type and has a repetitive sequence motif (ACCCTCCCC)4. The mutated NSE was examined for transcriptional activity
Triple-stranded_DNA
Protein-coding gene in humans
conserved, "acatalytic" carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11)
Carbonic anhydrase-related protein 11
Carbonic_anhydrase-related_protein_11
Type of base-pair DNA sequence
A protospacer adjacent motif (PAM) is a 2–6-base pair DNA sequence immediately following the DNA sequence targeted by the Cas9 nuclease in the CRISPR bacterial
Protospacer_adjacent_motif
Process of extracting design information from anything artificial
related although no causation can be simply inferred from coexpression. Sequence motif methods analyze gene promoters to find specific transcription factor
Reverse_engineering
Protein that regulates the rate of DNA transcription
information from DNA to messenger RNA, by binding to DNA sequences. Specificity can be due to sequence motifs, or epigenetic modifications. The function of TFs
Transcription_factor
Commonly used representation of patterns in biological sequences
commonly used representation of motifs (patterns) in biological sequences. PWMs are often derived from a set of aligned sequences that are thought to be functionally
Position_weight_matrix
Protein-coding gene in the species Homo sapiens
organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists
LSM6
Short, constantly recurring musical phrase
Leitmotiv (IPA: [ˈlaɪtmoˌtiːf] ), literally meaning "leading motif", or "guiding motif". A musical motif has been defined as a "short musical idea ... melodic
Leitmotif
RNA family
SELEX has been used to show that Hfq binding RNAs are enriched in the sequence motif 5′-AAYAAYAA-3′. Genome-wide study identified 40 candidate Hfq-dependent
Hfq_binding_sRNA
HbYX motif is a short, evolutionarily conserved peptide sequence found at the C‑termini of several proteasome activators. The "Hb" at the beginning of
HbYX_motifs
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SEQUENCE MOTIF
SEQUENCE MOTIF
Boy/Male
Tamil
Symbol, First word in a sentence
Boy/Male
Tamil
Sentence
Girl/Female
Indian, Sanskrit
Sentence
Boy/Male
Indian, Sanskrit
Order; Sequence
Girl/Female
Biblical
A dividing, a sentence.
Girl/Female
Indian
Sentence, Writing, Essay
Girl/Female
Tamil
Anuloma | அநà¯à®²à¯‹à®®à®¾
Sequence
Anuloma | அநà¯à®²à¯‹à®®à®¾
Girl/Female
Biblical
Dividing, sentence.
Girl/Female
Hindu
Line, Sentence
Biblical
a dividing; a sentence
Girl/Female
Tamil
Line, Sentence
Boy/Male
Hindu
Sentence
Boy/Male
Indian, Sikh
Music; In-sequence
Boy/Male
Tamil
Symbol, First word in a sentence
Girl/Female
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Telugu
Sequence
Girl/Female
Hindu, Indian
Sentence
Girl/Female
Hindu
Line, Sentence
Girl/Female
Tamil
Line, Sentence
Girl/Female
Muslim
Sentence, Writing, Essay
Biblical
dividing, sentence
SEQUENCE MOTIF
SEQUENCE MOTIF
SEQUENCE MOTIF
SEQUENCE MOTIF
SEQUENCE MOTIF
SEQUENCE MOTIF
SEQUENCE MOTIF
travel, tourism, insurance