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Type of medication
A sympatholytic (sympathoplegic) drug is a medication that reduces activity of the sympathetic nervous system (SNS). They are indicated for various conditions;
Sympatholytic
Local anesthetic drug
blocker. Today, it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion-enhancing, and mood-enhancing effects
Procaine
Type of substances designed to affect the nervous system
which mimics the action of sympathetic nervous system activation; and sympatholytic drugs which reduce or interrupt the action of sympathetic nervous system
Autonomic_drug
Catecholamine hormone and neurotransmitter
effects of norepinephrine released by the sympathetic nervous system; sympatholytic drugs, in contrast, block at least some of the effects. Both of these
Norepinephrine
Sedative medication
buccal or sublingual film. Similar to clonidine, dexmedetomidine is a sympatholytic drug that acts as an agonist of α2-adrenergic receptors in certain parts
Dexmedetomidine
Class of medications used to alleviate anxiety
elderly, hypersalivation, ataxia, slurred speech, psychomotor effects. Sympatholytics are a group of anti-hypertensives which inhibit activity of the sympathetic
Anxiolytic
Chemical compound
potential treatment of central nervous system conditions. The drug has sympatholytic and hypotensive effects in animals. It is highly ionic and may not be
Pyridoxiphen
Treatment for erectile dysfunction
effective blockade of the epinephrine pressor response and a smaller sympatholytic effect (63). An alpha-adrenergic antagonist with equal affinity for
Trimix_(drug)
Substance that mimics effects of catecholamines
found in Ephedra species) Adrenergic storm Sympathetic nervous system Sympatholytic Kirov E (9 November 2021). Herlihy's the Human Body in Health and Illness
Sympathomimetic_drug
Class of drugs
has two subclasses, α1 and α2. Alpha 2 receptors are associated with sympatholytic properties, while alpha 1 receptors are associated with sympathomimetic
Alpha-adrenergic_agonist
Chemical compound
Bethanidine (or betanidine) is a sympatholytic drug. Phenoxybenzamine Prichard BN, Johnston AW, Hill ID, Rosenheim ML (January 1968). "Bethanidine, Guanethidine
Bethanidine
Dopamine agonist medication
1111/1440-1681.13678. PMID 35635035. Defronzo RA (April 2011). "Bromocriptine: a sympatholytic, d2-dopamine agonist for the treatment of type 2 diabetes". Diabetes
Bromocriptine
Group of stereoisomers
hyperplasia. The bladder neck is densely packed with alpha-1 receptors. Sympatholytic drugs, including prazosin and doxazosin, are used for nightmares and
Doxazosin
Typical antipsychotic medication
vertigo, and weight gain) α1- and α2-adrenergic receptors (accounting for sympatholytic properties, lowering of blood pressure, reflex tachycardia, vertigo
Chlorpromazine
Typical antipsychotic medication
akathisia. Levomepromazine has prominent sedative and anticholinergic/sympatholytic effects (dry mouth, hypotension, sinus tachycardia, night sweats) and
Levomepromazine
Medical condition
ulceration or large artery thrombotic events may be prescribed aspirin. Sympatholytic agents, such as the alpha-adrenergic blocker prazosin, may provide temporary
Raynaud_syndrome
Antihypertensive drug
Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist. Although an initial report
Urapidil
Substance related to dopamine functions
and deutetrabenazine act as dopamine depleting agents and are used as sympatholytics or antihypertensives, to treat tardive dyskinesia, and in the past as
Dopaminergic
Class of CNS depressant drugs
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Benzodiazepine
SSRI antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Escitalopram
Antidepressant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Trazodone
Medication used to treat anxiety disorders
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Buspirone
Beta blocker drug
warfarin. Propranolol is classified as a competitive non-cardioselective sympatholytic beta blocker that crosses the blood–brain barrier. It is lipid soluble
Propranolol
SSRI antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Sertraline
Chemical compound
Guanoxan is a sympatholytic drug that was marketed as Envacar by Pfizer in the UK to treat high blood pressure. It was not widely used and was eventually
Guanoxan
Chemical compound
Trimazosin is a sympatholytic alpha-1 blocker. van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin
Trimazosin
Class of antidepressant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Selective serotonin reuptake inhibitor
Selective_serotonin_reuptake_inhibitor
Chemical compound
trimethaphan camsylate (USAN), sold under the trade name Arfonad, is a sympatholytic drug that is infrequently used to lower blood pressure. Trimetaphan
Trimetaphan_camsilate
Antihypertensive medication
"Pharmacology and clinical use of moxonidine, a new centrally acting sympatholytic antihypertensive agent". Journal of Human Hypertension. 11 (Suppl 1):
Moxonidine
Anticonvulsant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Pregabalin
Serotonin modulator antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Vortioxetine
Tricyclic antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Amitriptyline
Heart rhythm medication
main action as a slowing of the rising phase of the action potential. Sympatholytic drugs (drugs blocking the effects of the sympathetic nervous system):
Antiarrhythmic_agent
Topics referred to by the same term
nuclear materials Tenex, a brand name for the medication guanfacine, a sympatholytic used to treat hypertension, ADHD and anxiety Tenex, a brand name for
TENEX
Pharmaceutical compound
International Nonproprietary Name; synonym Luvion) is a drug described as a sympatholytic, antihypertensive, and vasodilator of the ergoline family which was
Brazergoline
Class of depressant drugs derived from barbituric acid
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Barbiturate
Alpha-adrenergic agonist
nervous system, and I1 activation has been implicated in clonidine's sympatholytic effect. One proposed model is that I1 receptor activation in the brainstem
Clonidine
Class of chemical compounds
Marini-Bettolo, G. B., Chiavarelli, S., & Bovet, D. (1951). Synthetic Sympatholytic Substances of the Ergotamine Series. I. Nitrogen-Substituted Derivatives
Partial_lysergamide
Medication class with multiple uses
importance in congestive heart failure. Beta blockers, in addition to their sympatholytic β1 activity in the heart, influence the renin–angiotensin system at
Beta_blocker
SSRI antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Fluvoxamine
Substance that mimics stimulation of cholinergic receptors
Oxymetazoline (partial α2 adrenergic agonist) Sympathomimetic drug Sympatholytics Dowd, Frank (2017). Pharmacology and therapeutics for dentistry: Chapter
Parasympathomimetic_drug
Medical condition
pharmacology such as beta-blockers, calcium channel blockers, digoxin, sympatholytic medication, and other antiarrhythmics can alter sinus node function
Sinus_node_dysfunction
Chemical compound
Guanoclor (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes. When β-(2
Guanoclor
CNS depressant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Phenibut
Muscle relaxant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Baclofen
Pharmaceutical compound
Castagnoli, 1975, 1977). The p-hydroquinone 120 is an analog of the sympatholytic agent 6-hydroxydopamine (107) and has been shown to possess some of
2,5-DDM-DOM
Chemical compound
Treatment. 9 (6): 916–21. PMID 13533786. Turner, Robert A. (1965). "12. Sympatholytic Agents. VI. The Two Kinds of Receptors". Screening Methods in Pharmacology
Ethylnorepinephrine
SNRI antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Venlafaxine
Benzodiazepine medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Alprazolam
Atypical antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Tianeptine
Benzodiazepine medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Lorazepam
Benzodiazepine sedative
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Diazepam
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
AR-A000002
Tricyclic antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Clomipramine
Gamma-aminobutyric acid analogs
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Gabapentinoid
Chemical stimulant produced by some plants
Potential interaction with sympathomimetic drugs (adrenergic agonists) and sympatholytic drugs (alpha-blockers and beta-blockers). Nicotine and cigarette smoke
Nicotine
Veterinary anesthetic, sedative and analgesic
Helminen A, Karhuvaara S (September 1998). "Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist
Xylazine
SSRI antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Fluoxetine
Antihistamine drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Hydroxyzine
Gabapentin prodrug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Gabapentin_enacarbil
Calcium channel blocker used in the treatment of migraine
Lomerizine Verapamil Flunarizine Progestogens Flumedroxone acetate Sympatholytics Beta blockers Propranolol# Timolol Clonidine Tricyclic antidepressants
Dotarizine
Benzodiazepine medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Clonazepam
Benzodiazepine derivative medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Nordazepam
Psychedelic drug
exceedingly huge amounts. Administration of anticoagulants, vasodilators, and sympatholytics may be useful for treating ergotism.[better source needed] Although
LSD
Chemical compound
Lomerizine Verapamil Flunarizine Progestogens Flumedroxone acetate Sympatholytics Beta blockers Propranolol# Timolol Clonidine Tricyclic antidepressants
Lisuride
(amphetamine–pyridoxine; pyridoxylamphetamine) – amphetamine derivative, sympatholytic, hypotensive agent Quifenadine (Phencarol, Fencarol) – antihistamine
List_of_Russian_drugs
Disorder resulting in recurrent moderate–severe headaches
Lomerizine Verapamil Flunarizine Progestogens Flumedroxone acetate Sympatholytics Beta blockers Propranolol# Timolol Clonidine Tricyclic antidepressants
Migraine
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Pirlindole
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Aprepitant
Benzodiazepine medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Chlordiazepoxide
Active ingredient in fermented drinks
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Alcohol_(drug)
Gamma-aminobutyric acid analog
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Gabapentin
Antidepressant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Mirtazapine
Benzodiazepine medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Oxazepam
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Ethyl_loflazepate
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Emoxypine
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
L-838,417
Carbamate derivative used as an anxiolytic
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Meprobamate
Class of psychoactive drugs
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Nonbenzodiazepine
Irreversible non-selective MAO inhibitor and antidepressant drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Phenelzine
Effect of low temperature on skin and other tissues
people get treatment within 48 hours. In addition to vasodilators, sympatholytic drugs can be used to counteract the detrimental peripheral vasoconstriction
Frostbite
Antihypertensive drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Prazosin
Sedating antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Doxepin
Beta blocker medication
β-Adrenergic receptor antagonist; Selective β1-adrenergic receptor antagonist; Sympatholytic agent; Antihypertensive agent; Anxiolytic ATC code C07AB03 (WHO) Legal
Atenolol
Pharmaceutical compound
indole moiety, in the structure of the ergot alkaloids is essential for sympatholytic activity. [...] Marini-Bettolo and co-workers (70) resolved the 2-aminotetralin
Tochergamine
Anxiolytic drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Binospirone
Benzodiazepine analog drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Etizolam
Medication used for migraines & cluster headaches
Lomerizine Verapamil Flunarizine Progestogens Flumedroxone acetate Sympatholytics Beta blockers Propranolol# Timolol Clonidine Tricyclic antidepressants
Sumatriptan
Family of enzymes
MAOs. Examples include substituted phenethylamine sympathomimetics and sympatholytics like phenylephrine, propranolol, and pronethalol, substituted tryptamine
Monoamine_oxidase
Benzodiazepine used for anesthesia and procedural sedation
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Midazolam
Benzodiazepine drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Bromazepam
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
NS-2664
SSRI antidepressant
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Citalopram
Antidepressant medication
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Olanzapine/fluoxetine
Atypical antidepressant drug
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
Nefazodone
Hallucinogenic class of psychoactive drug
Castagnoli, 1975, 1977). The p-hydroquinone 120 is an analog of the sympatholytic agent 6-hydroxydopamine (107) and has been shown to possess some of
Psychedelic_drug
Chemical compound
phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine Sympatholytics (Antiadrenergics) Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists
NS-2710
Drug class
Lomerizine Verapamil Flunarizine Progestogens Flumedroxone acetate Sympatholytics Beta blockers Propranolol# Timolol Clonidine Tricyclic antidepressants
Ditan
Abandoned sympatholytic drug
of the pertine group described as an antiadrenergic (or adrenolytic/sympatholytic) and as also potentially possessing neuroleptic properties which was
Solypertine
Chemical compound
Lomerizine Verapamil Flunarizine Progestogens Flumedroxone acetate Sympatholytics Beta blockers Propranolol# Timolol Clonidine Tricyclic antidepressants
Atogepant
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