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Long-term biobank study of 500,000 people
UK Biobank is a long-term prospective biobank study in the United Kingdom (UK) that houses the de-identified biological samples and health-related data
UK_Biobank
Far-right organization
accessed UK Biobank data. Hidden camera footage revealed Matthew Frost in 2023 claiming that "they've managed to get access to the UK Biobank," and to
Human_Diversity_Foundation
A biobank is a physical place which stores biological specimens. In some cases, participant data is also collected and stored. Access policies details
List_of_biobanks
British neurologist
Informatics at the University of Edinburgh. She is the Chief Scientist of UK Biobank, an honorary Consultant Neurologist in the Division of Clinical Neurosciences
Cathie_Sudlow
British epidemiologist and academic
is based in the Clinical Trial Service Unit, and Chief Scientist for UK Biobank. She is interested in the role of diet and obesity in cancer development
Naomi_Allen_(scientist)
British physician
2005, he has been the Principal Investigator and Chief Executive of the UK Biobank, a prospective study of 500,000 British people aged 40–69 at recruitment
Rory_Collins
Material from an organism used for biological research
and Biobanking. 8 (3): 153–162. doi:10.1089/bio.2010.0009. PMC 3129811. PMID 21743826. Elliott, P.; Peakman, T. C.; Uk, B. (2008). "The UK Biobank sample
Biological_specimen
autosomal genome above a specified length, termed Froh. A research study in UK Biobank, All of Us and Million Veteran Program found that FROH declined over time
Runs_of_homozygosity
Online database providing biobank data
virtual biobank is a virtual repository which provides data extracted from and characterizing samples stored at classical biobanks. Virtual biobanks are large
Virtual_biobank
Canadian and Dutch sociologist
the Economy, is a Trustee of the UK Biobank, on the Scientific and Ethics Advisory Boards of Our Future Health UK and Data and Management Committee
Melinda_Mills
Aberration of vision due to asymmetry in the eye's lens or cornea
A.; UK Biobank Eye and Vision Consortium (December 2018). "Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate
Astigmatism
Personality hypothesis which describes two contrasting personality types
"The influence of personality on the risk of myocardial infarction in UK Biobank cohort". Scientific Reports. 12 (1): 6706. Bibcode:2022NatSR..12.6706D
Type A and Type B personality theory
Type_A_and_Type_B_personality_theory
Percent of variation in IQ scores in a given population associated with genetic variation
Nonadopted Individuals Reveals Gene–Environment Interplay for Education in the UK Biobank". Psychological Science. 31 (5): 582–591. doi:10.1177/0956797620904450
Heritability_of_IQ
Large-scale brain network active when not focusing on an external task
default. Recent evidence from a population brain-imaging study of 10,000 UK Biobank participants further suggests that each DMN node can be decomposed into
Default_mode_network
British healthcare research charity established in 1936
Institute, a non-profit, British genomics and genetics research institute. UK Biobank. The KEMRI-Wellcome Trust Research Programme, established in 1989 in partnership
Wellcome_Trust
Flexitarian diet
all-cause mortality and a reduced cancer risk in participants from NHANES and UK Biobank. Poor diets are a major cause of health problems and death, due to both
Planetary_health_diet
British scientist
Strategy in January 2012. In this capacity she was a director of both UK Biobank and the Francis Crick Institute. Ewart retired as the Deputy Chief Executive
Wendy_Ewart
Chromosome disorder in women
estimated 2% of cases medically recognized. Amongst the 244,000 women in the UK Biobank research sample, 110 were found to have 47,XXX karyotypes, corresponding
Trisomy_X
retrospective cohort analyses performed in that study, using men from the UK BioBank who shared Beethoven’s genetic risk factors, did not reveal a high prevalence
Death_of_Ludwig_van_Beethoven
British radio and television presenter (born 1947)
Advisory Board, a member of the ethics committee of UK Biobank, and a Trustee of Crimestoppers and of the UK Stem Cell Foundation. He was one of the founders
Nick_Ross
Octogenarian who is cognitively much younger
predictors of potential super-ager and cognitive decline trajectories—a UK Biobank Random Forest classification study". GeroScience. 45 (1): 491–505. doi:10
Superager
Proportion of variance that two traits share due to genetic causes
and humans, and showed they are of similar sizes; for example, in the UK Biobank, of 118 continuous human traits, only 29% of their intercorrelations have
Genetic_correlation
British politician (born 1958)
Prinsley co-authored a study entitled "Epidemiology of Cholesteatoma in the UK Biobank", published in Clinical Otolaryngology. Prinsley has been a regional director
Peter_Prinsley
DNA located in mitochondria
phenotypes including lifespan and disease risks. In 2021, the largest, UK Biobank-based, genome-wide association study of mitochondrial DNA unveiled 260
Mitochondrial_DNA
Human hair color
Jackson, Ian J. (10 December 2018). "Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability". Nature Communications. 9 (1):
Red_hair
Short period of sleep during typical waking hours
cognitive function, and brain volume? A Mendelian randomization study in the UK Biobank". Sleep Health. 9 (5): 786–793. doi:10.1016/j.sleh.2023.05.002. PMID 37344293
Nap
British physician and academic (born 1950)
of the GMC, elected deputy chair of UK Biobank in 2005, and was on the board of trustees at Arthritis Research UK and at the Picker Institute. With his
Mike_Pringle_(physician)
Symptoms that occur after discontinuing antidepressant medication
and cardiometabolic correlates of ketohexokinase gene variants among UK Biobank participants". PLOS ONE. 16 (2) e0247683. Bibcode:2021PLoSO..1647683J
Antidepressant discontinuation syndrome
Antidepressant_discontinuation_syndrome
X chromosome monosomy
affects height in Turner syndrome; a large population sample drawn from the UK Biobank found women with 45,X0 karyotypes to have an average height of 145 cm
Turner_syndrome
Sequencing all the DNA of an individual at once
biomedical studies by U.K. effort". www.science.org. Retrieved 11 December 2021. "Whole Genome Sequencing data on 200,000 UK Biobank participants available
Whole_genome_sequencing
Medication against high blood pressure
Channel Blocker Use and Associated Glaucoma and Related Traits Among UK Biobank Participants". JAMA Ophthalmology. 141 (10): 956–964. doi:10.1001/jamaophthalmol
Amlodipine
Discipline in genetics
critical component of the precision medicine research platform and the UK Biobank initiative has studied more than 500.000 individuals with deep genomic
Genomics
Lung disease involving long-term poor airflow
Smokers Are at Greater Risk of Airflow Obstruction Than Male Smokers. UK Biobank" (PDF). American Journal of Respiratory and Critical Care Medicine. 195
Chronic obstructive pulmonary disease
Chronic_obstructive_pulmonary_disease
Effect of alcohol consumption on the brain
and MRI markers of brain structure and function: Cohort study of 25,378 UK Biobank participants". NeuroImage: Clinical. 35 103066. doi:10.1016/j.nicl.2022
Long-term impact of alcohol on the brain
Long-term_impact_of_alcohol_on_the_brain
Compression of the ulnar nerve in the elbow
Akira (2026-03-11). "The epidemiology of cubital tunnel syndrome: a UK Biobank case-control study". The Journal of Hand Surgery (European Volume) 17531934261426700
Cubital_tunnel_syndrome
American neuroscientist and academic
combination of MRI with light and electron microscopy. Miller developed the UK Biobank brain imaging protocols, which could help to identify new biomarkers of
Karla_Miller
Mammalian protein found in humans
immune parameters in humans: Evidence from 329,261 participants of the UK Biobank cohort". iScience. 24 (4) 102255. doi:10.1016/j.isci.2021.102255. PMC 8010467
C-reactive_protein
Fold in the surface of the brain
2022). "Genetic map of regional sulcal morphology in the human brain from UK biobank data". Nature Communications. 13 (1): 6071. Bibcode:2022NatCo..13.6071S
Sulcus_(neuroanatomy)
Time spent on any device with a screen
attenuated by strength, fitness and physical activity: findings from the UK Biobank study". BMC Medicine. 16 (1): 77. doi:10.1186/s12916-018-1063-1. ISSN 1741-7015
Screen_time
minimum term of 23 years. The UK government confirms that medical information of 500,000 participants in the UK's Biobank programme was offered for sale
2026_in_the_United_Kingdom
Provisioner of scientific consumables, equipment, and services
biotechnology field. In January 2025, Thermo Fisher partnered with the UK Biobank Pharma Proteomics Project (UKB-PPP) to support the world’s largest human
Thermo_Fisher_Scientific
Brain imaging software package
tool in the processing pipelines of the Human Connectome Project, the UK Biobank, the Adolescent Brain Cognitive Development Study, and the Alzheimer's
FreeSurfer
DNA sequences with no known biological function
Ulfarsson MO, et al. (July 2022). "The sequences of 150,119 genomes in the UK Biobank". Nature. 607 (7920): 732–740. Bibcode:2022Natur.607..732H. doi:10
Junk_DNA
Risks and possible benefits of drinking coffee
Improved Liver Outcomes: Clinical, Imaging, and Proteomic Evidence From the UK Biobank". Clinical Gastroenterology and Hepatology. 2026 (0). Cedars-Sinai Medical
Health_effects_of_coffee
Medical condition of the brain
(2022). "Prediagnostic Progressive Supranuclear Palsy: Insights from the UK Biobank". Parkinsonism & Related Disorders. 96: 56–61. doi:10.1016/j.parkreldis
Progressive supranuclear palsy
Progressive_supranuclear_palsy
for the purpose of storing and analyzing DNA sample. For example; The UK Biobank contains DNA samples of 500,000 individuals aged between 40 and 69 when
DNA_bank
relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study. - PubMed - NCBI". Nature Communications. 9 (1): 1612. doi:10
Protein-truncating_variants
Mammalian protein found in humans
disease. A genome-wide association study involving subjects from the UK Biobank further established an association of alcoholic-related liver disease
Mitochondrial amidoxime reducing component 1
Mitochondrial_amidoxime_reducing_component_1
Central nervous system disease
records indicates that 45 (with 22 of these being replicated with the UK Biobank) viral exposures can significantly elevate risks of neurodegenerative
Neurodegenerative_disease
Neurological factors responsible for intelligence
high-quality tests are used. A large scale study (n = 29k) using the UK Biobank found a correlation of .275. The strength of this relationship did not
Neuroscience_and_intelligence
Study of genetic variants in different individuals
GWAS summary statistics from seventeen pain susceptibility traits in the UK Biobank and revealed 99 genome-wide significant risk loci, among which 34 loci
Genome-wide_association_study
Person's daily sleep preferences
"Sleep and cognitive performance: cross-sectional associations in the UK Biobank". Sleep Medicine. 38: 85–91. doi:10.1016/j.sleep.2017.07.001. PMC 5930168
Chronotype
Branch of genomics concerned with the genome of an individual
Orleans. "Personal Genome Project". Retrieved 26 August 2025. "UK Biobank". UK Biobank. Retrieved 26 August 2025. "Genomic Vault". Switzerland Omics.
Personal_genomics
American physicist (born 1966)
traits (height, bone density, cognitive ability), using data from the UK Biobank. Their genotype height predictor estimated adult height within an accuracy
Stephen_Hsu
National medical research agency
(HDBR) Regulatory Support Centre Research Complex at Harwell UK Biobank UK Stem Cell Bank UK Clinical Research Collaboration (UKCRC) Tissue Directory International
Medical Research Council (United Kingdom)
Medical_Research_Council_(United_Kingdom)
Science collective
2017). "Professor Richard Durbin, FRS". www.gen.cam.ac.uk. Retrieved 19 August 2022. "Professor Tim Hubbard". www.kcl.ac.uk. Retrieved 19 August 2022.
Genome_Reference_Consortium
Genetic condition in which a male has an extra Y chromosome
"Detection and characterization of male sex chromosome abnormalities in the UK Biobank study". Genetics in Medicine. 24 (9). Elsevier: 1909–1919. doi:10.1016/j
XYY_syndrome
Longitudinal cohort study
Germany. Million Women Study, UK. Rotterdam Study, Netherlands. Tsimane’ Amazonian Panel Study, Bolivia The UK biobank , UK Retrospective cohort study Blinded
Prospective_cohort_study
Scottish psychiatrist and researcher
impact of mild cognitive impairment on healthcare utilization and costs: A UK Biobank study." Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Craig_Ritchie
Type of paternal lineage
of Y Chromosome Variation on Coronary Artery Disease and Mortality in UK Biobank—Brief Report". Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Haplogroup_R1b
Long-term high blood pressure in the arteries
urate, gout and comorbidities: a case–control study using data from the UK Biobank". Rheumatology. 60 (7): 3243–3251. doi:10.1093/rheumatology/keaa773. ISSN 1462-0324
Hypertension
Protein found in humans
food group intakes and circulating insulin-like growth factor-I in the UK Biobank: a cross-sectional analysis". European Journal of Nutrition. 62 (1): 115–124
Insulin-like_growth_factor_1
Scottish neuroscientist
and Mendelian Randomisation Study of Polygenic Risk for Depression in UK Biobank Shen X, et al. Nature Communications, 2020 11 (1) The neurobiology of
Heather_Whalley
Topics referred to by the same term
UKBB may refer to: UK Biobank University Children's Hospital Basel, an independent, university-based centre of competence for paediatric and juvenile medicine
UKBB
Biological evolution of Homo sapiens from 50,000 years ago until present
Kaiser Permanente in Northern California, and of 150,000 people in the UK Biobank, evolutionary geneticist Joseph Pickrell and evolutionary biologist Molly
Recent_human_evolution
British genomics research institute
created in 2019 to investigate the diversity of complex organisms found in the UK through sequencing and cellular technologies. It also compares and contrasts
Wellcome_Sanger_Institute
Sequencing of all the exons of a genome
September 2021). "Rare variant contribution to human disease in 281,104 UK Biobank exomes". Nature. 597 (7877): 527–532. Bibcode:2021Natur.597..527W. doi:10
Exome_sequencing
Vertebrate brain region
"Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank". NeuroImage Clin. 23 101904. doi:10.1016/j.nicl.2019.101904. PMC 6603440
Hippocampus
Biological process of getting older
predictors of potential super-ager and cognitive decline trajectories—a UK Biobank Random Forest classification study". GeroScience. 45 (1): 491–505. doi:10
Ageing
Biomedical research centre in London
The Francis Crick Institute (formerly the UK Centre for Medical Research and Innovation) is a biomedical research centre in London, which was established
Francis_Crick_Institute
Characteristics of the brain that differentiate the male brain and the female brain
(2018). "Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants". Cerebral Cortex. 28 (8): 6–7. bioRxiv 10.1101/123729. doi:10
Neuroscience of sex differences
Neuroscience_of_sex_differences
Open-access scientific journal
Human Genome Project Malawi Liverpool Wellcome Trust MEROPS Pfam Rfam UK Biobank Wellcome Collection Wellcome Genome Campus Wellcome Library WormBase Board
ELife
British epidemiologist and professor (born c. 1968)
informatics team that enabled the collection and management of data for the UK Biobank on over half a million people. Landray was born the son of a general practitioner
Martin_Landray
Canadian immunologist and geneticist (born 1952)
trustees of the Oxford Health Alliance and the science committee of the UK Biobank. He chairs the Global Health Scientific advisory board of the Bill & Melinda
John_Bell_(physician)
British large-scale health project
disease, and analysing the genetic data linked to immune dysfunction. UK Biobank, a similar project "Home page". Our Future Health. Retrieved 11 April
Our_Future_Health
Alzheimer's disease developed before the age of 65
et al. (December 26, 2023). "Risk Factors for Young-Onset Dementia in the UK Biobank". JAMA Neurology. 81 (2): 134–142. doi:10.1001/jamaneurol.2023.4929. ISSN 2168-6149
Early-onset Alzheimer's disease
Early-onset_Alzheimer's_disease
Unpleasant emotion
the common genetic architecture of anxiety have been facilitated by the UK Biobank, the ANGST consortium and the CRC Fear, Anxiety and Anxiety Disorders
Anxiety
Former Director General of MI5 (born 1948)
information which the Service may have about extraordinary renditions using UK airports". On 9 November 2006, Manningham-Buller gave a speech to the Mile
Eliza_Manningham-Buller
Chemical database of bioactive molecules also having drug-like properties
Biology Laboratory (EMBL), based at the Wellcome Trust Genome Campus, Hinxton, UK. The database, originally known as StARlite, was developed by a biotechnology
ChEMBL
Anatomical composition of the Neanderthal body
populations are associated with lighter or darker skin colour in the UK Biobank. DNA analysis of three Neanderthal females from southeastern Europe indicates
Neanderthal_anatomy
Chemical compound
C, Ducamp S, Zhu Z, Feng YC, Naik H, et al. (2021). "Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria". Genetics in
Afamelanotide
Vibratory sound made while asleep
aetiology of snoring from observational and genetic investigations in the UK Biobank". Nature Communications. 11 (1) 817. Bibcode:2020NatCo..11..817C. doi:10
Snoring
Medical imaging technique
using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort". Journal of Cardiovascular Magnetic Resonance. 19 (1)
Magnetic_resonance_imaging
by U.K. effort". Science.org. Retrieved 11 December 2021. "Whole Genome Sequencing data on 200,000 UK Biobank participants available now". UkBiobank.ac
2021_in_science
Luso-British epidemiologist
October 2024). "Small Airways Obstruction and Mortality: Findings From the UK Biobank". CHEST. 166 (4): 712–720. doi:10.1016/j.chest.2024.04.016. Amaral, Andre
André_Amaral
Professor of Statistical Genomics
responsible for the haplotype estimation and genotype imputation for the UK Biobank dataset. He co-leads the Haplotype Reference Consortium. He has been an
Jonathan_Marchini
Australian physician (born 1959)
years as a member of the International Scientific Advisory Board of the UK Biobank Research Project based at Oxford University. From 2008–10, he was the
Michael_Kidd_(physician)
Unpleasant emotional response to social or physical isolation
relationships reduced the risk by three-fifths. And based on the large UK Biobank cohort, a study found that individuals who reported feeling lonely had
Loneliness
Theory of sexual orientation
Jan; Blanchard, Ray (January 2025). "Birth Order and Family Size of UK Biobank Subjects Identified as Asexual, Bisexual, Heterosexual, or Homosexual
Fraternal birth order and male sexual orientation
Fraternal_birth_order_and_male_sexual_orientation
mass index, and socioeconomic status: mendelian randomisation study in UK Biobank". BMJ. 352: i582. doi:10.1136/bmj.i582. PMC 4783516. PMID 26956984. Taki
Height_and_intelligence
Museum and library in London, England
On Show In London At Wellcome Collection". culture24.org.uk. "Antony Gormley". Telegraph.co.uk. 13 March 2007.{{cite news}}: CS1 maint: deprecated archival
Wellcome_Collection
Icelandic biopharmaceutical company
informed the authorization of the UK Biobank in 2003 and then Genomics England in 2013. Other early, large-scale biobank and genomics efforts linked to major
DeCODE_genetics
British farming organisation
Human Genome Project Malawi Liverpool Wellcome Trust MEROPS Pfam Rfam UK Biobank Wellcome Collection Wellcome Genome Campus Wellcome Library WormBase Board
Farmcare
brain stem of COVID-19 patients. Brain-scans and cognitive tests of 785 UK Biobank participants (401 positive cases) suggests COVID-19 is associated with
Impact of COVID-19 on neurological, psychological and other mental health outcomes
Impact_of_COVID-19_on_neurological,_psychological_and_other_mental_health_outcomes
Evolutionary effects of sexual selection on humans
"Polygenic signals of sex differences in selection in humans from the UK Biobank". PLOS Biol. 20 (9) e3001768. doi:10.1371/journal.pbio.3001768. PMC 9481184
Sexual_selection_in_humans
Protein controlling mammalian coloration
Sims D, et al. (December 2018). "Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability". Nature Communications. 9 (1) 5271
Melanocortin_1_receptor
Anglo-American businessman (1853–1936)
departments to educate and train the researchers of the future. After changes in UK charity law the foundation was sold to GSK and the receipts invested in a
Henry_Wellcome
Finnish genomic research organisation
getting older, so they can be related to many more disease events than the UK Biobank. The concept of ‘broad consent’ means that participants do not have to
FinnGen
International scientific research project (1990–2003)
government through the National Institutes of Health in the United States, and a UK charity organization, the Wellcome Trust, as well as numerous other groups
Human_Genome_Project
Scientific project at the European Bioinformatics Institute
Human Genome Project Malawi Liverpool Wellcome Trust MEROPS Pfam Rfam UK Biobank Wellcome Collection Wellcome Genome Campus Wellcome Library WormBase Board
Ensembl genome database project
Ensembl_genome_database_project
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