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Pharmaceutical compound
2C-E, also known as 4-ethyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally. The drug acts
2C-E
Airborne early warning and control aircraft
piston-engined E-1 Tracer, which was rapidly becoming obsolete. The aircraft's performance has been upgraded with the E-2B and E-2C versions, where most
Grumman_E-2_Hawkeye
Family of phenethylamine psychedelics
including 2C-C, 2C-D, 2C-E, 2C-I, and 2C-T-2 among others, are inactive as monoamine releasing agents and reuptake inhibitors. Most of the 2C drugs are
2C_(psychedelics)
Psychedelic drug
(α-methyl-2C-B) DOM (α-methyl-2C-D) 4C-B (α-ethyl-2C-B) β-Methyl-2C-B (BMB) BOH-2C-B (BOHB; β-hydroxy-2C-B) BOB (β-methoxy-2C-B) βk-2C-B (β-keto-2C-B) 2C-DB
2C-B
Psychedelic designer drug
2C-E-FLY is a recreational designer drug with psychedelic effects of the phenethylamine, 2C, and FLY families. It is slightly less potent than 2C-E or
2C-E-FLY
Pharmaceutical compound
2C-I, also known as 4-iodo-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally. 2C-I was first
2C-I
Naturally occurring psychedelic compound
most important phenethylamine compounds together with mescaline, 2C-E, 2C-T-7, and 2C-T-2. Bryan Wynter produced Mars Ascends after trying the substance
Mescaline
Pharmaceutical compound
2C-D has been described. Analogues of 2C-D include 2C-B, 2C-E, 2C-P, other 2Cs, DOM (α-methyl-2C-D), Ariadne (4C-D; α-ethyl-2C-D), 5C-D (α-propyl-2C-D)
2C-D
Pharmaceutical compound
2C-G, or 2C-G-0, also known as 3,4-dimethyl-2,5-dimethoxyphenethylamine or as 3-methyl-2C-D, is a psychedelic phenethylamine of the 2C family. First synthesized
2C-G
Pharmaceutical compound
chemical synthesis of 2C-P has been described. Analogues of 2C-P include 2C-D, 2C-E, 2C-Bu, 2C-iP, 2C-iBu, DOPR, and 4C-P, among others. 2C-P was first described
2C-P
South American psychoactive decoction
non-religious adaptations, and the development of ayahuasca analogues (i.e., variants) using local or synthetic ingredients. While DMT is internationally
Ayahuasca
Synthetic hallucinogen
25I-NBOMe, also known as 2C-I-NBOMe, Cimbi-5, and shortened to "25I", is a psychedelic drug of the phenethylamine, 2C, and NBOMe (25-NB) families. Since
25I-NBOMe
Pharmaceutical compound
2C-5-TOET, also known as 2-methoxy-4-ethyl-5-methylthiophenethylamine or as 5-thio-2C-E, is a chemical compound and possible psychedelic drug of the phenethylamine
2C-5-TOET
Chemical compound found in some species of mushrooms
doi:10.1016/j.aca.2004.08.071. Lindenblatt H, Krämer E, Holzmann-Erens P, Gouzoulis-Mayfrank E, Kovar KA (May 1998). "Quantitation of psilocin in human
Psilocybin
Reciprocating internal combustion engine
Camry/Vista 1983-1985 The 2C was a long running diesel engine, with some models (e.g. Corona, Townace, Liteace) receiving the turbo version 2C-T which provided
Toyota_C_engine
Pharmaceutical compound
These drugs include 2C-B, 2C-C, 2C-D, 2C-E, and 2C-I, among others. The N-methyl derivative of 2C-H, N-methyl-2C-H, has reduced activational potency
2C-H
Psychedelic drug
tolerance (see Subsect. E.III). Canal CE, Olaghere da Silva UB, Gresch PJ, Watt EE, Sanders-Bush E, Airey DC (April 2010). "The serotonin 2C receptor potently
Dimethyltryptamine
Monoamine neurotransmitter
receptors, including the serotonin 5-HT1 (1A, 1B, 1D, 1E, 1F), 5-HT2 (2A, 2B, 2C), 5-HT3, 5-HT4, 5-HT5 (5A, 5B), 5-HT6, and 5-HT7 receptors. Except for the
Serotonin
Pharmaceutical compound
2C-C, also known as 4-chloro-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally. 2C-C was first
2C-C
Chemical compound
25E-NBOMe, also known as 2C-E-NBOMe or NBOMe-2C-E, is a derivative of the phenethylamine 2C-E. It acts in a similar manner to related compounds such as
25E-NBOMe
Hallucinogenic class of psychoactive drug
the 2C drugs like 2C-B, 2C-E, and 2C-I, the DOx drugs like DOM, DOB, DOI, certain MDxx drugs like MDA and MDMA (weak psychedelics), FLY drugs like 2C-B-FLY
Psychedelic_drug
March 2024. "LSD, MDMA & 2C-B use and combination in Therapy". Chemical-Collective. 12 March 2023. Retrieved 1 May 2023. "DXM & 2C-B - Erowid Exp - 'Nexuswalk
List_of_drug_combinations
Psychoactive substance found in plants in the family Apocynaceae
the synaptogenesis induced by ibogaine is blocked by ketanserin, a 5-HT2A/2C antagonist (Ly et al., 2018). Ly C, Greb AC, Cameron LP, Wong JM, Barragan
Ibogaine
Muscle relaxant medication
43 nM), adrenergic α-1A (5.6 and 34 nM), α-2B (Ki = 21 and 150 nM) and α-2C (Ki = 21 and 48 nM,); H1 (1.3 and 5.6 nM); and M1 (7.9 and 30 nM). Like CBP
Cyclobenzaprine
Antidepressant medication
Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Mirtazapine
Common name for more than 1,000 species of flowering plants in the family Convolvulaceae
cold. Some species are strictly annual (e.g. Ipomoea nil), producing many seeds, and some perennial species (e.g. I. indica) are propagated by cuttings
Morning_glory
Psychedelic phenthylamine drug
2C-T-7, also known as 4-propylthio-2,5-dimethoxyphenethylamine or as Blue Mystic or 7th Heaven, is a psychedelic drug of the phenethylamine and 2C families
2C-T-7
Species of psychoactive cactus
S. E. & Malenka, R. C. (2001). "Addiction and the brain: The neurobiology of compulsion and its persistence." Neuroscience. 2;696 K B Nolte and R E Zumwalt
Peyote
Medication used for high blood pressure and ADHD
alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors". The Journal of Pharmacology and
Guanfacine
Chemical compound
25E-NBOH (2C-E-NBOH, NBOH-2C-E) is a derivative of the phenethylamine derived hallucinogen 2C-E. It was first developed by Martin Hansen at the University
25E-NBOH
Medication mainly used for depression and smoking cessation
PMC 5947828. PMID 29377409. Livingstone-Banks J, Norris E, Hartmann-Boyce J, West R, Jarvis M, Chubb E, et al. (October 2019). "Relapse prevention interventions
Bupropion
Pharmaceutical compound
compound of the 2C-T series of psychedelic phenethylamines, with derivatives such as 2C-T-2, 2C-T-4, 2C-T-7, and 2C-T-21, among many others. 2C-T was first
2C-T
Chemical compound
This profile of effects has been described as being analogous to the case of 2C-B. In addition to its use on its own, 4-HO-MET, along with the related tryptamine
4-HO-MET
Atypical antipsychotic medication
was sometimes an antagonist (e.g., at 5-HT6), sometimes an inverse agonist (e.g., 5-HT2B), sometimes a partial agonist (e.g., D2S, D3S, D4S, D2L). Aripiprazole
Aripiprazole
Antidepressant medication
characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors". Naunyn-Schmiedeberg's Arch. Pharmacol. 370 (2): 114–23. doi:10
Trazodone
Chemical compound
Central nervous system Khat Substituted cathinone Hosseinian A, Vessally E, Bekhradnia A, Nejati K, Rahimpour G (31 October 2017). "Benzoylethanamine
Cathinone
Genus of plants
original on 5 May 2015. Retrieved 17 November 2015. Nambiar, E.K. Sadanandan; Harwood, Christopher E.; Kien, Nguyen Duc (2015). "Acacia plantations in Vietnam:
Acacia
Psychedelic drug
2C-B-FLY is a psychedelic and designer drug of the phenethylamine, 2C, and FLY families. It was first described in 1995 by Aaron Monte, Professor of Chemistry
2C-B-FLY
Mushrooms containing psychoactive indole alkaloids
mushrooms (in that case, among the Mexican [Nahuatl] Indians). Brande E. (1799). "Mr. E. Brande, on a poisonous species of Agaric". The Medical and Physical
Psilocybin_mushroom
Species of fungus native to Europe
Science Series. 49 (4): 747––752. doi:10.26692/Surj/2017.12.52. Brande E. (1799). "Mr. E. Brande, on a poisonous species of Agaric". The Medical and Physical
Psilocybe_semilanceata
Pharmaceutical compound
2C-DB, also known as 2,5-dimethoxy-4,6-dibromophenethylamine or as 6-bromo-2C-B, is a psychedelic drug of the phenethylamine and 2C families related to
2C-DB
Species of amphibian
troughs. The Colorado River toad is known to breed in artificial water bodies (e.g., flood control impoundments, reservoirs) and as a result, the distributions
Colorado_River_toad
Fungi of the genus Claviceps
culminating on the one hand in development of drugs both legal (e.g., bromocriptine) and illegal (e.g., LSD), and on the other hand in extensive knowledge of
Ergot
Species of fungus
considered a "container" for psilocybin based on how the law is written, i.e., it does not specifically state that psilocybin mushrooms themselves are
Psilocybe_cubensis
Psychedelic drug
psychedelic drug of the phenethylamine and 2C families. It was first synthesized in the laboratory of David E. Nichols. Later, it was tested in humans and
2C-TFM
CHCl3, historical anaesthetic and common solvent
(This had caused me to impose the name "chloroform" upon this substance [i.e., formyl chloride or chloride of formic acid].) In 1835, Dumas prepared the
Chloroform
Catecholamine hormone and neurotransmitter
colleague Arturo Rosenblueth developed a theory of two sympathins, sympathin E (excitatory) and sympathin I (inhibitory), responsible for these actions.
Norepinephrine
Antihistamine drug
British Medical Association. 2017. p. X. ISBN 978-0-85711-298-9. Shorter E (2009). Before Prozac: the troubled history of mood disorders in psychiatry
Hydroxyzine
Psychoactive drug, often called ecstasy
LSD, psilocybin mushrooms, 2C-B, and ketamine. The combination with LSD is called "candy-flipping". The combination with 2C-B is called "nexus flipping"
MDMA
Pharmaceutical compound
2C-iBu, or 2C-IB, also known as 4-isobutyl-2,5-dimethoxyphenethylamine or by its developmental code name ELE-02, is a serotonin 5-HT2A receptor agonist
2C-iBu
Atypical antipsychotic medication
Wallace TJ, Zai CC, Brandl EJ, Müller DJ (18 August 2011). "Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain". Pharmacogenomics
Olanzapine
Weight loss medication
No. 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Phentermine
Mescaline-containing cactus
one reason it is widely cultivated as an ornamental and landscaping plant. E. pachanoi is normally 3–6 m (10–20 ft) tall and has multiple branches, usually
Echinopsis_pachanoi
Medication to prevent nausea and vomiting
September 2020. "Zofran Product and Consumer Medicine Information Licence". TGA eBS. Archived from the original on 29 August 2022. Retrieved 28 August 2022
Ondansetron
Chemical element with atomic number 54 (Xe)
(PDF). Chinese Physics C. 45 (3) 030001. doi:10.1088/1674-1137/abddae. Aprile E, Abe K, Agostini F, Ahmed Maouloud S, Alfonsi M, Althueser L, et al. (August
Xenon
Atypical antipsychotic medication
extrapyramidal side-effect liability. Owing to the risks associated with clozapine (e.g. agranulocytosis, diabetes mellitus, etc.), clinicians often attempt treatment
Quetiapine
Medication used to treat anxiety disorders
Structures and Bibliographies. Springer. pp. 192–. ISBN 978-1-4757-2085-3. "TGA eBS - Product and Consumer Medicine Information Licence". "Anksilon (Orion Pharma
Buspirone
Pharmaceutical compound
including of the serotonin 5-HT2A receptor. Analogues of DOM include mescaline, 2C-D, DOET, DOB, DOI, and Ariadne (4C-D), among others. DOM was first synthesized
2,5-Dimethoxy-4-methylamphetamine
2,5-Dimethoxy-4-methylamphetamine
Pharmaceutical compound
2C-G-5, also known as 3,4-norbornyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is one of several homologues
2C-G-5
Psychedelic drug
(October 2005). "SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist". Bioorganic & Medicinal Chemistry Letters. 15 (20): 4555–4559. doi:10
Psilocin
Psychoactive substance that induces spiritual experiences
2004; Sobiecki 2002, 2008, 2012). Among the amaXhosa, the artificial drug 2C-B is used as entheogen by traditional healers or amagqirha over their traditional
Entheogen
Pharmaceutical compound
2C-T-2, also known as 4-ethylthio-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally. The drug
2C-T-2
Pharmaceutical compound
UCD0120-2C-D is a possible serotonergic psychedelic of the phenethylamine and 2C families. It is a cyclized phenethylamine and a partial or simplified
UCD0120-2C-D
Central nervous system stimulant
can precipitate unpredictable and rapid mood swings, stimulant psychosis (e.g., paranoia, hallucinations, delirium, and delusions), and aggression. Recreationally
Methamphetamine
Antipsychotic medication
autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are long-acting
Risperidone
Entactogen, stimulant, and psychedelic drug of the amphetamine family
robust self-report VAS changes in both MDMA-like (e.g., "closeness to others") and hallucinogen-like (e.g., "familiar things seem unfamiliar", time distortions
3,4-Methylenedioxyamphetamine
Psychedelic drug
The DEA performed a chromatographic analysis of blotter paper containing 2C-C which showed that the paper contained a much greater concentration of the
LSD
Atypical antidepressant classified primarily as a melatonin receptor agonist
ISSN 1432-2072. Norman TR (May 2012). "The effect of agomelatine on 5HT(2C) receptors in humans: a clinically relevant mechanism?". Psychopharmacology
Agomelatine
Antihistamine medication
Heisler LK, Zhou L, Bajwa P, Hsu J, Tecott LH (July 2007). "Serotonin 5-HT(2C) receptors regulate anxiety-like behavior". Genes, Brain and Behavior. 6 (5):
Diphenhydramine
Psychedelic drug
Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists
5-MeO-DMT
Medication mainly used to treat gout
number of chromosomes (i.e., tetraploid instead of diploid), and lead to cell nuclei with double the usual number of chromosomes (i.e., tetraploid instead
Colchicine
Perennial flowering plant in the coffee family Rubiaceae
side of this scar there is a dense, usually furry line of fine trichomes (i.e., plant hairs) usually 0.5–1 mm (0.020–0.039 in) long that are reddish brown
Psychotria_viridis
Drug mixture used mainly to treat ADHD and narcolepsy
cause rapid muscle breakdown, provoke panic attacks, or induce psychosis (e.g., paranoia, delusions, hallucinations). The side effects vary widely among
Adderall
1991 book by Alexander Shulgin and Ann Shulgin
follows: 2C-B (2,5-dimethoxy-4-bromophenethylamine) 2C-E (2,5-dimethoxy-4-ethylphenethylamine) 2C-T-2 (2,5-dimethoxy-4-ethylthiophenethylamine) 2C-T-7 (2
PiHKAL
Chemical compound responsible for rotten fish odor
1–9, doi:10.1002/3527600418.mb7550e0914, ISBN 978-3-527-60041-0 Cramer, R. E.; Bopp, T. T. (1977). "Graphical display of the enthalpies of adduct formation
Trimethylamine
Pharmaceutical compound
other notable 2C psychedelics including 2C-B, 2C-D, 2C-T, 2C-P, and 2C-T-7. The chemical synthesis of 2C-CN has been described. 2C-CN is the 2C parent compound
2C-CN
Species of fungus
2022.01.003. ISSN 1878-6146. PMID 35314062. Windsor, Coleton; Kreynes, Anna E; Chilton, Jeff S; Chioffi, William A; Niebergall, Christopher; Dodds, Kelsey
Psilocybe_azurescens
2C-B 2CB-2OCD3 2CB-5OCD3 2C-Bu 2C-C 2C-CN 2C-CP 2C-D 2C-E 2C-EF 2C-F 2C-H 2C-I 2C-iBu 2C-iP 2C-N 2C-P 2C-Se 2C-Se-TFM 2C-tBu 2C-TFE 2C-TFM 2C-YN 2C-V
List_of_psychedelic_drugs
Serotonin modulator antidepressant
interactions with a variety of assessed cytochrome P450 enzymes and transporters (e.g., P-glycoprotein), hence vortioxetine is not expected to influence the pharmacokinetics
Vortioxetine
Class of chemical compounds
David E. Nichols and colleagues at Purdue University by 1995. 2C-B-FLY 2C-B-ButterFLY (2C-B-MOTH) 2C-B-DragonFLY (2C-B-DFLY) 2C-B-5-hemiFLY 2C-C-FLY 2C-I-FLY
FLY_(psychedelics)
CNS stimulant and isomer of amphetamine
anxiety, and irritability, among others. At excessive doses, psychosis (i.e., hallucinations, delusions), addiction, and rapid muscle breakdown may occur
Dextroamphetamine
Beta blocker drug
Propranolol is useful in the treatment of acute cardiovascular toxicity (e.g. in overdose) caused by sympathomimetics like amphetamine, methamphetamine
Propranolol
Pharmaceutical compound
2C-Ph, or 2C-Phenyl, also known as 2C-BI-1 or as 2,5-dimethoxy-4-phenylphenethylamine, is a serotonin receptor modulator of the phenethylamine and 2C
2C-Ph
Chemical compound
N-Ethyl-2C-B, also known as 2C-B-E, is a psychedelic drug of the phenethylamine and 2C families related to 2C-B. It is the N-ethyl derivative of 2C-B. The
N-Ethyl-2C-B
Pharmaceutical compound
2-OH-2C-B, also known as 2-O-desmethyl-2C-B (2-DM-2C-B) or as 4-bromo-2-hydroxy-5-methoxyphenethylamine (B-2-HMPEA), is a serotonin receptor modulator
2-OH-2C-B
Synthetic opioid pain medication
(May 2004). "The inhibitory effects of tramadol on 5-hydroxytryptamine type 2C receptors expressed in Xenopus oocytes". Anesthesia and Analgesia. 98 (5):
Tramadol
Chemical compound
βk-2C-B, or bk-2C-B, also known as 4-bromo-2,5-dimethoxy-β-ketophenethylamine or as β-keto-2C-B, is a psychedelic drug of the phenethylamine and 2C family
Βk-2C-B
Sedating antihistamine
1016/j.ejmech.2016.03.045. PMID 27043269. Bolshan Y, Getlik M, Kuznetsova E, Wasney GA, Hajian T, Poda G, et al. (March 2013). "Synthesis, Optimization
Promethazine
Species of flowering plant
improvements in sleep and mild nervous tension symptoms. Germany's Commission E, the scientific advisory board responsible for evaluating the safety and efficacy
Valerian_(herb)
Chemical compound
effects having not yet been explored. Analogues of 2C-CP include 2C-CPE, 2C-IP, 2C-P, 2C-T-15, 2C-V, and 2C-YN, among others. The drug is a controlled substance
2C-CP
Central nervous system stimulant
stimulant therapy for ADHD is effective for reducing the core symptoms of ADHD (i.e., hyperactivity, inattention, and impulsivity), enhancing quality of life
Amphetamine
Pharmaceutical compound
drug of the phenethylamine, 2C, and TWEETIO families related to the psychedelic drug 2C-E. It is the derivative of 2C-E in which the methoxy group at
2CE-5-EtO
SSRI antidepressant
NSAIDs, antiplatelet drugs, anticoagulants, omega-3 fatty acids, vitamin E, and garlic supplements must be careful when taking fluoxetine or other SSRIs
Fluoxetine
Class of chemical compounds
Fitzpatrick, D.; Hall, W. C.; LaMantia, A. S.; McNamara, J. O.; White, L. E., eds. (2008). Neuroscience (4th ed.). Sinauer Associates. pp. 137–138.
Catecholamine
Pharmaceutical compound
Division, January 2026 2C-B-AN - Isomer Design The Small & Handy 2C-B-AN / 2C-B-Aminonitrile Thread (2C-B-prodrug) - Bluelight 2C-B-AN - TripSit v t e
2C-B-AN
Species of fungus
(2): 181–95. doi:10.33585/cmy.64207. Borovička, Jan; Noordeloos, Machiel E.; Gryndler, Milan; Oborník, Miroslav (2010). "Molecular phylogeny of Psilocybe
Psilocybe_cyanescens
Pharmaceutical compound
93%. 2C-Bu follows 2C-D, 2C-E, and 2C-P in the homologous series of 4-alkylated 2C derivatives. Higher homologues of 2C-Bu including 2C-Am and 2C-Hx are
2C-Bu
Species of plant
ISSN 0102-695X. Archived (PDF) from the original on 2010-08-21. Rivera-Arce E, Chávez-Soto MA, Herrera-Arellano A, et al. (February 2007). "Therapeutic
Mimosa_tenuiflora
Pharmaceutical compound
However, the HTR induced by 2C-T-27 is relatively weak. Analogues of 2C-T-27 include 2C-T-6, 2C-T-31, and 2C-T-33, among others. 2C-T-27 was first synthesized
2C-T-27
Typical antipsychotic medication
Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Chlorpromazine
travel, tourism, insurance
2C E
2C E
2C E
2C E
2C E
2C E
2C E
2C E
2C E
travel, tourism, insurance