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Genetic information manifested elsewhere
Ectopic is a word used with a prefix ecto-, meaning "out of", and the suffix -topic, meaning "place." Ectopic expression is an abnormal gene expression
Ectopic_expression
Protein and coding gene in humans
are members of the ATP:guanido phosphotransferase protein family. Ectopic expression (CKBE) of the B (brain) type of creatine kinase (CK-BB) in red cells
CKB_(gene)
Cats with genetic anomaly that causes extra toes
mirroring smaller ectopic expression in a new organizer region is seen on the posterior side of the limb. This ectopic expression causes cell proliferation
Polydactyl_cat
Protein-coding gene in mammals
mutation (Ay) and the viable yellow mutation (Avy) which are caused by ectopic expression of agouti. These mutations are also associated with yellow obese syndrome
Agouti-signaling_protein
Type of gene involved in flagellin reception of bacteria
performed to show involvement of FLS2 in flagellin perception was an ectopic expression of FLS2 using the CaMV 35S gene promoter in one wild type Arabidopsis
FLS2
Attachment of an embryo outside the uterus
Ectopic pregnancy is a complication of pregnancy in which the embryo attaches outside the uterus. This complication has also been referred to as an extrauterine
Ectopic_pregnancy
Physical anomaly involving extra fingers or toes
the mutant, smaller ectopic expression in a new organiser region is seen on the anterior side of the limb. This ectopic expression causes cell proliferation
Polydactyly
Protein-coding gene in the species Homo sapiens
small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine
Ubiquitin carboxy-terminal hydrolase L1
Ubiquitin_carboxy-terminal_hydrolase_L1
Chinese fluffy breed of chicken
of the SHH gene, called the ZPA regulatory sequence. This causes ectopic SHH expression in the anterior of the developing limb bud, leading to increased
Silkie_(chicken_breed)
Displacement or malposition of an organ or other body part
Ectopic enamel, a tooth abnormality, where enamel is found in an unusual location, such as at the root of a tooth Ectopic expression, the expression of
Ectopia_(medicine)
Critical protein in embryonic development
signaling activities of the notochord and floor plate. Studies involving ectopic expression of SHH in vitro and in vivo result in floor plate induction and differentiation
Sonic_hedgehog_protein
Class of enzymes
gene protein CKB creatine kinase, brain, BB-CK CKBE creatine kinase, ectopic expression CKM creatine kinase, muscle, MM-CK CKMT1A, CKMT1B creatine kinase
Creatine_kinase
Promiscuous gene expression (PGE), formerly referred to as ectopic expression, is a process specific to the thymus that plays a pivotal role in the establishment
Promiscuous_gene_expression
Domesticated subspecies of red junglefowl
2016). "A Complex Structural Variation on Chromosome 27 Leads to the Ectopic Expression of HOXB8 and the Muffs and Beard Phenotype in Chickens". PLOS Genetics
Chicken
Process by which light activates retinal cells
1999). "Blue- and green-absorbing visual pigments of Drosophila: ectopic expression and physiological characterization of the R8 photoreceptor cell-specific
Visual_phototransduction
Class of transport proteins
J, Ma YP, Olshevskaya E, Pu M, Dizhoor AM, et al. (April 2006). "Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with
Channelrhodopsin
Process of stem cells differentiating into fat cells
differentiation is a change of gene expression patterns which multipotent gene expression alters to cell type specific gene expression. Therefore, transcription
Adipogenesis
Structure in early amniote embryogenesis
hypoblast, Nodal is unable to induce ectopic streaks in the chick embryo, while its removal, induces expression of Nodal, Chordin, and Brachyury, suggesting
Primitive_streak
Nitrogen-fixing cells
PMID 11133933. Higa, Kelly C.; Callahan, Sean M. (1 August 2010). "Ectopic expression of hetP can partially bypass the need for hetR in heterocyst differentiation
Heterocyst
Protein found in humans
placenta. Ectopic expression of CDX2 was reported in more than 85% of the human patients with acute myeloid leukemia (AML). Ectopic expression of Cdx2 in
Homeobox_protein_CDX-2
Mammalian protein found in Homo sapiens
(January 2013). "The manipulation of neural and cellular activities by ectopic expression of melanopsin". Neuroscience Research. 75 (1): 3–5. doi:10.1016/j
Melanopsin
Negative regulation (or limiting) of body weight and cell proliferation
the injection, these bladder carcinoma cells did not express H19. Ectopic H19 expression in vivo enhances the tumorigenic potential of carcinoma cells c-Myc
H19_(gene)
Sex-linked mutation
they experience a reduced rate of sexual arousal during daylight. Ectopic expression of white+ induces male-male courtship in Drosophila. White+ controls
White_(mutation)
Structure formed early in vertebrate limb development
Although excess retinoic acid can alter limb patterning by ectopically activating Shh expression, genetic studies in mouse that eliminate retinoic acid synthesis
Limb_bud
Protein-coding gene in the species Homo sapiens
elevated medium chain phospholipids in tissues and in blood. Conversely, ectopic expression of ABHD3 prevents the accumulation of oxidized phospholipids in cells
ABHD3
Hox gene
R, Gehring WJ (1987). "Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia". Nature. 325 (6107): 816–8. Bibcode:1987Natur
Antennapedia
Protein-coding gene in the species Homo sapiens
duplications of tunnel of Corti and inner hair cells, as well as ectopic expression of patches of vestibular-like hair cells in Kolliker's organ. The
SOBP
Ability of a cell to differentiate into other cell types
"The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression". Development. 139 (13): 2288–2298. doi:10.1242/dev.078071. PMC 3367440
Cell_potency
Dyad symmetry Dystonia E (exit site) Ecdysone Ecological genetics Ectopic expression Electrophoresis Electroporation ELSI Endomitosis Endonuclease Endopolyploidy
Index_of_genetics_articles
Gene responsible for color variations in many species
PMID 8202545. Klebig ML, Wilkinson JE, Geisler JG, Woychik RP (May 1995). "Ectopic expression of the agouti gene in transgenic mice causes obesity, features of
Agouti_coloration_genetics
Reversible biological process
suggested that ectopic expression of Klf4 in iPS cell reprogramming may be specifically responsible for inducing E-cadherin expression by binding to promoter
Mesenchymal–epithelial transition
Mesenchymal–epithelial_transition
Group of chicken breeds
Ning Li (2012). The Crest Phenotype in Chicken Is Associated with Ectopic Expression of HOXC8 in Cranial Skin. PLOS ONE. 7 (4): e34012. doi:10.1371/journal
Crested_chickens
Mammalian protein found in Homo sapiens
domains: Oct-4 has been implicated in tumorigenesis of adult germ cells. Ectopic expression of the factor in adult mice has been found to cause the formation
Oct-4
Genus of grass cultivated for grain
Nikolai M.; Simmonds, James; Brinton, Jemima F.; et al. (1 May 2021). "Ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains
Wheat
RNA family
pattern of expression, but this is unlikely to be a dominant effect since the 744 base-pair ftz zebra stripe element can drive the ectopic expression of a reporter
FIE3 (ftz instability element 3′) element
FIE3_(ftz_instability_element_3′)_element
Anti-apoptotic viral protein
virus. Although baculoviruses infect only invertebrates in nature, ectopic expression of P35 in vertebrate animals and cells also results in inhibition
Early_35_kDa_protein
American immunologist (born 1951)
differentiation and shown to activate IFN-γ expression while repressing the opposing TH2 cytokine program. Ectopic expression of T-bet could redirect polarized
Laurie_Glimcher
Family of oncogenic microRNAs
Altered expression of the miR-569 gene has been demonstrated to affect growth and proliferation of breast epithelial cells. Ectopic expression of miR-569
Oncomir
RNA binding protein
Acloque H, Bachelard E, Nieto MA, Samarut J, Pain B (June 2009). "Ectopic expression of Cvh (Chicken Vasa homologue) mediates the reprogramming of chicken
Vasa_gene
Artificial peptide attached to protein for marking purpose
291–300. doi:10.1016/0092-8674(86)90746-4. McMahon AP, Moon RT (1989). "Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication
Protein_tag
Non-coding RNA in the species Homo sapiens
FAS-AS1 expression. EZH2-mediated repression of FAS-AS1 promoter can be released by DZNeP (3-Deazaneplanocin A) or overcome by ectopic expression of FAS-AS1
FAS-AS1
Myles; Doonan, John H; Nibau, Candida; Uauy, Cristobal (2021-05-01). "Ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains
Tunica_(biology)
Mammalian protein found in humans
expression of NANOG stimulates Rex1 expression. Besides the effects of NANOG in the embryonic stages of life, ectopic expression of NANOG in the adult stem cells
Homeobox_protein_NANOG
Agricultural developments in 1950s–1960s
"Decreased shoot stature and grain alpha-amylase activity following ectopic expression of a gibberellin 2-oxidase gene in transgenic wheat". J. Exp. Bot
Green_Revolution
Protein-coding gene in the species Homo sapiens
The expression of the KLF15 gene is markedly up-regulated during the differentiation of 3T3-L1 preadipocytes into adipocytes. Ectopic expression of KLF15
KLF15
Protein-coding gene in the species Homo sapiens
Weinberg RA (1992). "Regulation of retinoblastoma protein functions by ectopic expression of human cyclins". Cell. 70 (6): 993–1006. doi:10.1016/0092-8674(92)90249-C
Cyclin_E1
Non-protein coding transcripts longer than 200 nucleotides
depends on the expression of an antisense transcript that complements the intronic 5' splice site. Therefore, the ectopic expression of the antisense
Long_non-coding_RNA
Protein complex that regulates the separation of sister chromatids during cell division
cellular phenotype of Roberts syndrome fibroblasts as revealed by ectopic expression of ESCO2". PLOS ONE. 4 (9) e6936. Bibcode:2009PLoSO...4.6936V. doi:10
Cohesin
Protein encoding gene in humans
oncogene-induced senescence (OIS) and diminishes the DNA-damage response. Also, ectopic expression of CXCR2 results in premature senescence via a p53-dependent mechanism
CXCR2
Gehring, Walter J. (1987). "Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia". Nature. 325 (6107): 816–818.
Homeosis
Protein-coding gene in the species Homo sapiens
Bavelloni A, Marin O, Lattanzi G, Blalock W, Cenni V (January 2021). "Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential
ANKRD2
American optogeneticist (born 1971)
Bi A; Cui J; Ma Y; Olshevskaya E; Pu M; Dizhoor A; Pan Z (2006). "Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with
Karl_Deisseroth
Mammalian protein found in humans
domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis". The Journal of Biological
Adipose_triglyceride_lipase
Protein-coding gene in the species Homo sapiens
when injected in vivo in the vitreous body. - In ectopic tumour in vivo models, induced expression of TNMD in mouse melanoma cells resulted in suppression
Tenomodulin
Small non-coding ribonucleic acid molecule
that they act as negative regulators of differentiation. Conversely, ectopic expression of the miRNAs 155, 221, and 222 significantly inhibited adipogenesis
MicroRNA
Induction of a significant reduction of size or stature in biological organisms
"Decreased shoot stature and grain alpha-amylase activity following ectopic expression of a gibberellin 2-oxidase gene in transgenic wheat". J. Exp. Bot
Dwarfing
Chemical compound
gene expression modulation, this return to wild-type phenotype is further evidence of Morpholino specificity. In some cases, ectopic expression of the
Morpholino_nucleic_acid
Scientific discipline
can be expressed in live cells, but present major limitations in ectopic expression and might cause a loss of function. Fluorescent techniques have been
Chemical_biology
Protein found in humans
on IRS-1 independent MAPK activation. When treated with insulin, ectopic expression of PTEN in MCF-7 suppresses IRS-1/Grb-2/Sos complex formation due
Insulin_receptor_substrate_1
Protein family
SA. Increased resistance to SA through WAK1 expression can only be conferred through ectopic expression of an entire WAK1 protein or kinase domain. This
Wall-associated_kinase
Transformation of large areas of cells into cancerous forms
Pitari GM, Schulz S, Waldman SA (April 2006). "Bile acids induce ectopic expression of intestinal guanylyl cyclase C through nuclear factor-kappaB and
Field_cancerization
Chemical entity which can be bound by an antibody
1126/science.1648265. PMID 1648265. McMahon AP, Moon RT (1989). "Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication
Epitope
Species of grass
(ORCID); Nibau, Candida (ORCID); Uauy, Cristobal (ORCID) (2021-05-01). "Ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains
Triticum_polonicum
Lab technique
adenine methylation exclusively in the palindromic sequence GATC. Ectopic expression of Dam in eukaryotic cells leads to methylation of adenine in GATC
DNA adenine methyltransferase identification
DNA_adenine_methyltransferase_identification
DNA pattern affecting anatomy development
R, Gehring WJ (1987). "Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia". Nature. 325 (6107): 816–8. Bibcode:1987Natur
Homeobox
Family of proteins
S2CID 10805017. Lee HG, Ueda M, Zhu X, Perry G, Smith MA (December 2006). "Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming
SMAD_(protein)
Modification in mRNA, DNA
inhibition on the circadian period in mouse cells can be prevented by ectopic expression of an enzyme from the bacterial methyl metabolism. Mouse cells expressing
N6-Methyladenosine
loss of stiffness-controlled transcription factor Cdx leads to the ectopic expression of inner cell mass markers in the trophectoderm, and the pluripotent
Mechanobiology
Mammalian protein found in Homo sapiens
osteosarcomas due to increased proliferation of osteoblasts whereas ectopic expression of the other Jun and Fos proteins does not induce any malignant tumors
Protein_c-Fos
Protein family
the SHORT VEGETATIVE PHASE gene family. ZMM19 can be ectopically expressed. Such ectopic expression of ZMM19 in A. thaliana enlarges sepals, suggesting
MADS-box
Protein-coding gene in the species Homo sapiens
muscle cells, human uterine myometrial cells, and leiomyoma cells. Ectopic expression of WISP-2 also inhibits the motility and invasiveness of breast carcinoma
CCN_family_member_5
Controlling biological cells with light
J, Ma YP, Olshevskaya E, Pu M, Dizhoor AM, Pan ZH (April 2006). "Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with
Optogenetics
Protein-coding gene in humans
expression". J. Biol. Chem. 277 (6): 3979–84. doi:10.1074/jbc.M106587200. PMID 11726653. Seko A, Nagata K, Yonezawa S, Yamashita K (2003). "Ectopic expression
CHST4
German scientist (born 1953)
K; Lim, K C; Plank, C; Beug, H; Engel, J D; Zenke, M (June 1993). "Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid
Martin_Zenke
Derivative of cholesterol obtained by oxidation
serum. 26-HC is elevated both in CSF and serum. In AD, CYP46A1 shows ectopic expression in astrocytes. It's thought that CYP46A1/24-HC is reflective of a
Oxysterol
Cell line
laboratory studies such as KSHV reactivation from latency with TPA or ectopic expression of KSHV ORF 50. BCP-1 has been deposited to ATCC by the creators for
BCP-1_cells
Protein-coding gene in the species Homo sapiens
M109728200. PMID 11959851. Kobayashi M, Taniura H, Yoshikawa K (2003). "Ectopic expression of necdin induces differentiation of mouse neuroblastoma cells". J
NDN_(gene)
Shuhui; Chen, Zheng; Xu, Guanghui; Nie, Yongzhan (2012-06-29). "Ectopic Expression of MiR-125a Inhibits the Proliferation and Metastasis of Hepatocellular
MiR-125
CCR-06-0865. PMID 16899600. Park J, Schulz S, Haaf J, et al. (2002). "Ectopic expression of guanylyl cyclase C in adenocarcinomas of the esophagus and stomach"
Guanylate_cyclase_2C
Proteins which remove GDP from GTPases
Fonseca R, Smyrk TC, Chari ST, Urrutia R, Billadeau DD (January 2005). "Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis"
Guanine nucleotide exchange factor
Guanine_nucleotide_exchange_factor
that SK-OV-3 were platinum sensitive. It was subsequently shown that ectopic expression of the MUC16 C-terminal domain in SK-OV-3 cells decreases their sensitivity
SK-OV-3
neuronal differentiation and self-renewal. A 2016 study found that ectopic expression of miR-9 in the mouse cortex prematurely activates NEUROD1 (a pro-neuronal
Epigenetic regulation of neurogenesis
Epigenetic_regulation_of_neurogenesis
Protein-coding gene in the species Homo sapiens
caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl". Carcinogenesis. 23 (1): 143–50. doi:10.1093/carcin/23
BH3 interacting-domain death agonist
BH3_interacting-domain_death_agonist
Protein-coding gene in the species Homo sapiens
researched under induced ectopic expression in cancerous conditions. The discovered association between apoptosis and an over expression of galectin-7 has been
Galectin-7
1998). "Correlation of wing-leg identity in ectopic FGF-induced chimeric limbs with the differential expression of chick Tbx5 and Tbx4". Development. 125
Apical_ectodermal_ridge
Protein found in mammals
"Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase". Nature Genetics. 2 (1): 66–74. doi:10.1038/ng0992-66
Steroid_11β-hydroxylase
Immune system protein
proteins that are normally restricted to peripheral tissues. This ectopic expression creates an "immunological self-shadow" that exposes developing T cells
Autoimmune_regulator
Protein-coding gene in humans
PMID 11956189. Tian YL, Liu FR, Liu J, Jiang L, Luo Y, Zhang X (2002). "[Ectopic expression of cyclin G2 inhibits cell proliferation in HeLa cancer cell line]"
CCNG2
Member of the cyclin family
(September 1992). "Regulation of retinoblastoma protein functions by ectopic expression of human cyclins". Cell. 70 (6): 993–1006. doi:10.1016/0092-8674(92)90249-c
Cyclin_E
Protein-coding gene in the species Homo sapiens
Muñoz-Galindo L, Ceballos-Cancino G, Maldonado V, Melendez-Zajgla J (2014). "Ectopic expression of new alternative splice variant of Smac/DIABLO increases mammospheres
Diablo_homolog
suppressors in human cancers, and NAT expression may be increased and decreased in cancer cells. Ectopic expression of hNaa10p increased cell proliferation
Protein_acetylation
Chinese neuroscientist (born 1956)
Ma, Y.-P., Olshevskaya, E., Pu, M., Dizhoor, A.M., and Pan Z.-H. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with
Zhuo-Hua_Pan
Protein-coding gene in the species Homo sapiens
response element in 3' long terminal repeat (LTR) of all viral RNAs. Ectopic expression of hnRNP A1 antagonizes post-transcriptional activity of Rex via competitive
HNRNPA1
Protein-coding gene in humans
Dawson TL, Schell MJ, Anwar AA, Snodgrass HR, Earp HS (May 2006). "Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic
MERTK
Protein-coding gene in the species Homo sapiens
T, French DM (2002). "A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice"
FGF19
Transcription factor gene of the SOX family
Sox2 expression is also found in high gleason grade prostate cancer, and promotes castration-resistant prostate cancer growth. The ectopic expression of
SOX2
Protein-coding gene in the species Homo sapiens
1563–8. PMID 11245466. Musiyenko A, Bitko V, Barik S (March 2008). "Ectopic expression of miR-126*, an intronic product of the vascular endothelial EGF-like
SLC45A3
Plant root which grows aboveground primarily for anchorage
Lafitte, H. Renee; Schussler, Jeffrey R.; Mo, Hua (2018-10-16). "Ectopic expression of ARGOS 8 reveals a role for ethylene in root-lodging resistance
Brace_roots
Protein family
ectopic expression of C/EBPα in various fibroblast cell lines promotes adipogenesis. C/EBPα probably promotes adipogenesis by inducing the expression
CCAAT-enhancer-binding proteins
CCAAT-enhancer-binding_proteins
Protein family
monitored with ectopic expression of pdf, which in this case is concentrated in the dorsal central brain. These alterations in expression caused severely
Pigment_dispersing_factor
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ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
ECTOPIC EXPRESSION
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