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ANTENNAPEDIA

• Antennapedia

Hox gene

Antennapedia (abbreviated Antp) is a Hox gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function

Antennapedia



Antennapedia

• Homeobox

DNA pattern affecting anatomy development

outright replacement of a discrete body part with another body part, e.g. antennapedia—replacement of the antenna on the head of a fruit fly with legs. The

Homeobox



Homeobox

• Hox gene

Group of genes

complement of Hox genes in Drosophila is made up of two clusters, the Antennapedia complex and the Bithorax complex, which together were historically referred

Hox gene

Hox_gene

• Homeotic gene

Genes regulating the development of anatomical structures in various organisms

genes, a subset of the ANTP class (named after the Drosophila gene, Antennapedia). They also include the MADS-box-containing genes involved in the ABC

Homeotic gene

Homeotic_gene

• Imaginal disc

One of the parts of a holometabolous insect larva

Drosophila melanogaster led to the discovery of homeotic mutations such as antennapedia, where the developmental fate of a disc could sometimes change. It is

Imaginal disc



Imaginal_disc

• Eyespot (mimicry)

Eye-like marking used for mimicry or distraction

development, including the genes called Engrailed, Distal-less, Hedgehog, Antennapedia, and the Notch signaling pathway. Artificial eyespots have been shown

Eyespot (mimicry)



Eyespot_(mimicry)

• Mutant

Phenotypically-different organism resulting from a mutation

Mol. Cell. 62 (5): 712–27. doi:10.1016/j.molcel.2016.04.006. PMC 5476208. PMID 27259203. Wikiquote has quotations related to Mutant. Antennapedia mutant

Mutant



Mutant

• Walter Jakob Gehring

Swiss developmental biologist (1939–2014)

1984). "A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes". Nature. 308 (5958): 428–433. Bibcode:1984Natur

Walter Jakob Gehring



Walter_Jakob_Gehring

• Homeosis

segments become mesothoracic segments. Another well-known example is Antennapedia: a gain-of-function allele causes legs to develop in the place of antennae

Homeosis



Homeosis

• Appendage

External body part or natural prolongation

2004). "Spatial and temporal regulation of the homeotic selector gene Antennapedia is required for the establishment of leg identity in Drosophila". Developmental

Appendage



Appendage

• Drosophila embryogenesis

Embryogenesis of the fruit fly Drosophila, a popular model system

anterior-posterior axis of the developing embryo. The Antennapedia group of homeotic selector genes includes labial, antennapedia, sex combs reduced, deformed, and proboscipedia

Drosophila embryogenesis



Drosophila_embryogenesis

• Michael Levine (biologist)

American biologist

of wings, showed a localized pattern of expression similar to that of Antennapedia, they decided to revisit the classic papers of Ed Lewis. In 1978, Lewis

Michael Levine (biologist)

Michael_Levine_(biologist)

• Peroxisome proliferator-activated receptor alpha

Nuclear receptor protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Peroxisome proliferator-activated receptor alpha



Peroxisome_proliferator-activated_receptor_alpha

• Receptor (biochemistry)

Protein molecule receiving signals for a cell

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Receptor (biochemistry)



Receptor_(biochemistry)

• Thomas Kaufman

American geneticist

where he remains. It was during this time that Kaufman defined the antennapedia gene complex. He discovered that this cluster of genes controlled the

Thomas Kaufman

Thomas_Kaufman

• Tulle Hazelrigg

American biologist

supervision of Thomas Kaufman. She elucidated the fine structure of the Antennapedia complex. She was a postdoctoral researcher at the Carnegie Institution

Tulle Hazelrigg

Tulle_Hazelrigg

• CREB

Class of proteins

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

CREB



CREB

• Heterochromatin protein 1

Protein family

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Heterochromatin protein 1

Heterochromatin_protein_1

• Estrogen receptor

Proteins activated by the hormone estrogen

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Estrogen receptor



Estrogen_receptor

• Alain Prochiantz

French professor and neurobiologist

Glowinski J, Prochiantz A. dans Nature du 16 février 1984;307(5952):641-3. Antennapedia homeobox peptide regulates neural morphogenesis.[link removed] par Joliot

Alain Prochiantz



Alain_Prochiantz

• Estrogen receptor beta

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Estrogen receptor beta



Estrogen_receptor_beta

• Retinoic acid receptor alpha

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Retinoic acid receptor alpha



Retinoic_acid_receptor_alpha

• WRKY transcription factor

Proteins that bind DNA

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

WRKY transcription factor

WRKY_transcription_factor

• Microphthalmia-associated transcription factor

Mammalian protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Microphthalmia-associated transcription factor



Microphthalmia-associated_transcription_factor

• GATA3

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

GATA3



GATA3

• NF-κB

Family of transcription factor protein complexes

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

NF-κB



NF-κB

• PROX2

Protein

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

PROX2

PROX2

• HES4

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

HES4



HES4

• Bithorax complex

right arm of chromosome 3 alongside the other homeotic gene complex, the Antennapedia (Antp) complex. It is over 300 kb long and contains nine distinct cis-regulatory

Bithorax complex



Bithorax_complex

• Morphogen

Biological substance that guides development by non-uniform distribution

AH, Chassaing G, Prochiantz A (April 1994). "The third helix of the Antennapedia homeodomain translocates through biological membranes". J. Biol. Chem

Morphogen



Morphogen

• Critical period

Maturational stage in the lifespan of an organism

Joliot A, Pernelle C, Deagostini-Bazin H, Prochiantz A (March 1991). "Antennapedia homeobox peptide regulates neural morphogenesis". Proceedings of the

Critical period

Critical_period

• P53

Mammalian protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

P53



P53

• Cynthia Kenyon

US molecular biologist

mab-5 contains a homeobox homologous to that of the Drosophila Hox gene Antennapedia. These findings contributed to the recognition that Hox genes form an

Cynthia Kenyon



Cynthia_Kenyon

• NFE2L2

Human protein and coding gene

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

NFE2L2



NFE2L2

• BARX homeobox 1

Human protein

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

BARX homeobox 1



BARX_homeobox_1

• Brain-specific homeobox

Protein encoded by the BSX gene

highly-conserved homeodomain-containing transcription factor that belongs to the [[Antennapedia |ANTP]]-class. In the hypothalamic arcuate nucleus, Bsx has been demonstrated

Brain-specific homeobox



Brain-specific_homeobox

• Transcription factor

Protein that regulates the rate of DNA transcription

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Transcription factor



Transcription_factor

• Zerknüllt

Protein family

Zerknüllt (zen, German for "crumpled") is a gene in the Antennapedia complex of Drosophila (fruit flies) and other insects, where it operates very differently

Zerknüllt

Zerknüllt

• Aryl hydrocarbon receptor

Vertebrate receptor protein and transcription factor

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Aryl hydrocarbon receptor



Aryl_hydrocarbon_receptor

• Androgen receptor

Mammalian protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Androgen receptor



Androgen_receptor

• Steroid hormone receptor

Group of protein families

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Steroid hormone receptor

Steroid_hormone_receptor

• REPIN1

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

REPIN1



REPIN1

• Glucocorticoid receptor

Receptor to which cortisol and other glucocorticoids bind

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Glucocorticoid receptor



Glucocorticoid_receptor

• Pair-rule gene

Gene involved in the development of segmented embryos of insects

"Analysis of larval segmentation in lethal genotypes associated with the antennapedia gene complex in Drosophila melanogaster". Dev. Biol. 81 (1): 51–64. doi:10

Pair-rule gene



Pair-rule_gene

• Myc

Family of regulator genes

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Myc

Myc

• Proboscipedia (fly gene)

palp, tarsus and proboscis identities. Proboscipedia belongs to the Antennapedia (Antp) homeobox family and the Proboscipedia subfamily. A homeobox gene

Proboscipedia (fly gene)

Proboscipedia_(fly_gene)

• Peroxisome proliferator-activated receptor

Group of nuclear receptor proteins

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Peroxisome proliferator-activated receptor



Peroxisome_proliferator-activated_receptor

• MYC

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

MYC



MYC

• Protein c-Fos

Mammalian protein found in Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Protein c-Fos



Protein_c-Fos

• Peroxisome proliferator-activated receptor gamma

Nuclear receptor protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Peroxisome proliferator-activated receptor gamma



Peroxisome_proliferator-activated_receptor_gamma

• T-box

Genes that affect limb and heart development

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

T-box



T-box

• Retinoid receptor

Nuclear receptors that bind to retinoids

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Retinoid receptor

Retinoid_receptor

• SPI1

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

SPI1



SPI1

• Sex-determining region Y protein

Protein that initiates male sex determination in therian mammals

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Sex-determining region Y protein



Sex-determining_region_Y_protein

• Retinoblastoma protein

Mammalian protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Retinoblastoma protein



Retinoblastoma_protein

• Wilms tumor protein

Transcription factor gene involved in the urogenital system

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Wilms tumor protein



Wilms_tumor_protein

• GATA2

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

GATA2



GATA2

• HOXA6

Protein-coding gene in the species Homo sapiens

SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX 1hom: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA

HOXA6



HOXA6

• Zbtb7

Mammalian protein found in Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Zbtb7

Zbtb7

• HOXB5

Protein-coding gene in humans

the PDB for UniProt: P02833 (Drosophila melanogaster Homeotic protein antennapedia) at the PDBe-KB. This article incorporates text from the United States

HOXB5



HOXB5

• HOXA7

Protein-coding gene in the species Homo sapiens

overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. Homeobox GRCh38: Ensembl release 89: ENSG00000122592

HOXA7



HOXA7

• Internal ribosome entry site

RNA element

IRES), Insulin-like growth factor 2 (IGF-II IRES) Transcription factors Antennapedia, Ultrabithorax, MYT-2, NF-κB repressing factor NRF, AML1/RUNX1, Gtx homeodomain

Internal ribosome entry site

Internal_ribosome_entry_site

• Retinoid X receptor

Genes on human chromosome 9

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Retinoid X receptor

Retinoid_X_receptor

• GSX2

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

GSX2



GSX2

• KMT2A

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

KMT2A



KMT2A

• FOXI3

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

FOXI3



FOXI3

• KLF2

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

KLF2



KLF2

• MAFK

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

MAFK



MAFK

• HOXB7

Protein-coding gene in humans

"Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain". Blood. 78 (4): 1047–1055. doi:10.1182/blood.V78.4.1047

HOXB7



HOXB7

• IRF9

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

IRF9



IRF9

• BAZ1B

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

BAZ1B



BAZ1B

• CLOCK

Human protein and coding gene

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

CLOCK



CLOCK

• PRDM16

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

PRDM16



PRDM16

• FOXP2

Transcription factor gene of the forkhead box family

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

FOXP2



FOXP2

• SMAD4

Mammalian protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

SMAD4



SMAD4

• CAMP responsive element modulator

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

CAMP responsive element modulator



CAMP_responsive_element_modulator

• Aryl hydrocarbon receptor nuclear translocator

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Aryl hydrocarbon receptor nuclear translocator



Aryl_hydrocarbon_receptor_nuclear_translocator

• COUP-TFII

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

COUP-TFII



COUP-TFII

• Small Maf

Class of proteins

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Small Maf

Small_Maf

• Pregnane X receptor

Mammalian protein found in Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Pregnane X receptor



Pregnane_X_receptor

• FOX proteins

Family of transcription factors involved in anatomical development

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

FOX proteins



FOX_proteins

• MNDA

Protein-coding gene in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

MNDA



MNDA

• MAFG

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

MAFG



MAFG

• Hypoxia-inducible factor

Protein that responds to low oxygen

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Hypoxia-inducible factor

Hypoxia-inducible_factor

• SMAD1

Protein found in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

SMAD1



SMAD1

• NRF1

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

NRF1



NRF1

• TBX3

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

TBX3



TBX3

• Vitamin D receptor

Transcription factor activated by vitamin D

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Vitamin D receptor



Vitamin_D_receptor

• PAX5

Protein-coding gene in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

PAX5



PAX5

• IKZF2

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

IKZF2



IKZF2

• Anti-sigma factors

Antagonists of a youth's slang

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Anti-sigma factors

Anti-sigma_factors

• Retinoic acid receptor

Type of nuclear receptor

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Retinoic acid receptor



Retinoic_acid_receptor

• ZNF143

Protein-coding gene

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

ZNF143



ZNF143

• KDM3B

Protein-coding gene in the species Homo sapiens

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

KDM3B



KDM3B

• HOXD13

Protein

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

HOXD13



HOXD13

• PAX6

Protein-coding gene in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

PAX6



PAX6

• NKX 2-9

Transcription factor

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

NKX 2-9

NKX_2-9

• RUNX2

Protein-coding gene in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

RUNX2



RUNX2

• NFKB1

Protein-coding gene in humans

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

NFKB1



NFKB1

• Basic helix–loop–helix

Protein structural motif

JMJD1B (2.6) WRKY WRKY (3) Helix-turn-helix domains (3.1) Homeodomain Antennapedia ANTP class protoHOX Hox-like ParaHox Gsx 1 2 Xlox PDX1 Cdx 1 2 4 extended

Basic helix–loop–helix



Basic_helix–loop–helix

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Affordable travel, tourism, home and auto insurance, legal services

travel, tourism, insurance

• Travel & tourism
• Home Insurance
• Auto Insurance
• Online Shopping
• Personal Injury Lawyer
• Dui Attorney
• Mesothelioma Lawsuit
• Car Insurance Quotes
• Mortgage Rates
• Life Insurance Comparison
• Insurance Policy
• Bankruptcy Lawyer
• Injury Lawyers
• Consolidate-personal-loans
• Loans
• personal-loans
• Weightloss Medication
• Check Credit Score
• Accident Lawyers
• Cheap Insurance
• Private Jet Charter Rates
• Cheap Flights
• Structured Settlements
• Rehab Facilities
• Video Conferencing
• Loans & Mortgages
• Charter Flights
• Health & Fitness
• Digital Marketing
• Wrongful Death Lawyers
• Mortgage Refinancing
• Best Online Advertising
• Online Degrees
• Shop Online
• Flight Deals
• Enterprise CRM
• Cyber Security Software
• Life Insurance Comparison
• Best Credit Cards
• Forex Trading Platform
• Crypto Trading
• Cloud Hosting
• Enterprise AI Platforms
• VPN Apps
• Online MBA Programs
• Coding Bootcamps
• Online College Business Degree