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Small-scale two-dimensional array of samples on a solid support
carbohydrate microarrays is expanding. Types of microarrays include: DNA microarrays, such as cDNA microarrays, oligonucleotide microarrays, BAC microarrays and
Microarray
Form of protein microarray
An antibody microarray (also known as antibody array) is a specific form of protein microarray. In this technology, a collection of captured antibodies
Antibody_microarray
Tissue arrangement technique
Tissue microarrays (also TMAs) consist of paraffin blocks in which up to 1000 separate tissue cores are assembled in array fashion to allow multiplex
Tissue_microarray
Collection of microscopic DNA spots attached to a solid surface
A DNA microarray (also commonly known as a DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA
DNA_microarray
Technology for phenotyping of cells
The phenotype microarray approach is a technology for high-throughput phenotyping of cells. A phenotype microarray system enables one to monitor simultaneously
Phenotype_microarray
Device for tracking proteins
A protein microarray (or protein chip) is a high-throughput method used to track the interactions and activities of proteins, and to determine their function
Protein_microarray
A cellular microarray (or cell microarray) is a laboratory tool that allows for the multiplex interrogation of living cells on the surface of a solid support
Cellular_microarray
PMHC cellular microarrays are a type of cellular microarray that has been spotted with pMHC complexes peptide-MHC class I or peptide-MHC class II. These
PMHC_cellular_microarray
Microarray analysis techniques are used in interpreting the data generated from experiments on DNA (Gene chip analysis), RNA, and protein microarrays
Microarray analysis techniques
Microarray_analysis_techniques
A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed on a solid surface, usually
Peptide_microarray
A microarray database is a repository containing microarray gene expression data. The key uses of a microarray database are to store the measurement data
Microarray_databases
Representational oligonucleotide microarray analysis (ROMA) is a technique that was developed by Michael Wigler and Rob Lucito at the Cold Spring Harbor
Representational oligonucleotide microarray analysis
Representational_oligonucleotide_microarray_analysis
Set of all RNA molecules in one cell or a population of cells
The first transcriptome studies were based on microarray techniques (also known as DNA chips). Microarrays consist of thin glass layers with spots on which
Transcriptome
This microarray format is very similar to DNA microarray, protein microarray and antibody microarray. In chemical genetics research, they are routinely
Chemical_compound_microarray
Process in machine learning and statistics
search and binary particle swarm optimization for feature selection using microarray data". Journal of Computational Biology. 16 (12): 1689–1703. doi:10.1089/cmb
Feature_selection
Minimum information about a microarray experiment (MIAME) is a standard created by the FGED Society for reporting microarray experiments. MIAME is intended
Minimum information about a microarray experiment
Minimum_information_about_a_microarray_experiment
Medical condition
1q21.1 microdeletion was first identified in 2008 through a chromosomal microarray studies published in Nature Genetics and the New England Journal of Medicine
1q21.1_deletion_syndrome
A reverse phase protein lysate microarray (RPMA) is a protein microarray designed as a dot-blot platform that allows measurement of protein expression
Reverse phase protein lysate microarray
Reverse_phase_protein_lysate_microarray
Branch of biology that studies biological systems at the molecular level
membrane are probed for modifications using specific substrates. A DNA microarray is a collection of spots attached to a solid support such as a microscope
Molecular_biology
Study of RNA transcripts
biological sciences. There are two key contemporary techniques in the field: microarrays, which quantify a set of predetermined sequences, and RNA-Seq, which
Transcriptomics_technologies
Computational analysis of large, complex sets of biological data
arrays identifying point mutations that cause cancer, oligonucleotide microarrays can be used to identify chromosomal gains and losses (called comparative
Bioinformatics
DNA reverse transcribed from RNA
profiles in bulk tissue, single cells, or single nuclei in assays such as microarrays, qPCR, and RNA-seq. In natural forms, cDNA is produced by retroviruses
Complementary_DNA
Class of short biopolymers
DNA microarrays are a useful analytical application of oligonucleotides. Compared to standard cDNA microarrays, oligonucleotide based microarrays have
Oligonucleotide
Method to evaluate biological samples
further explored by other cytological techniques. Through the use of DNA microarrays in conjunction with CGH techniques, the more specific form of array CGH
Comparative genomic hybridization
Comparative_genomic_hybridization
Substrates performing biochemical reactions
differentiated. Microarrays are not limited to DNA analysis; protein microarrays, antibody microarray, chemical compound microarray can also be produced
Biochip
Gene expression data repository
are derived from microarray or RNA-Seq experimental data. These data need to conform to the minimum information about a microarray experiment (MIAME)
Gene_Expression_Omnibus
used to calibrate measurements in RNA hybridization assays, such as DNA microarray experiments, RT-qPCR, and RNA-Seq. A spike-in is designed to bind to a
RNA_spike-in
Microtechnology
such, peptide microarrays have been used to complement protein microarrays in proteomics research and diagnostics. Protein microarrays usually use Escherichia
Bio-MEMS
Bioinformatics association
the life sciences and biomedical communities. Founded in 1999 as the "Microarray Gene Expression Data (MGED) Society", this organization changed its name
FGED_Society
Genomic study of immune system regulation and pathogen response
benefit from cDNA microarray analysis of gene expression,” and, thus, heralded the rise of immunomics. Limited by available microarrays and a non-complete
Immunomics
steps in protocols for Southern blotting, in situ hybridization, DNA Microarray or Northern blotting. 20X SSC may be used to prevent drying of agarose
SSC_buffer
Technique used to map epigenetic methylations in cancer DNA
Methylation specific oligonucleotide microarray, also known as MSO microarray, was developed as a technique to map epigenetic methylation changes in DNA
Methylation specific oligonucleotide microarray
Methylation_specific_oligonucleotide_microarray
Collection of techniques used to analyze biological markers in the genome and proteome
The detection of the marker might use real time PCR, direct sequencing, microarray chips—prefabricated chips that test many markers at once, or MALDI-TOF
Molecular_diagnostics
Medical condition
abnormality found in a recent study using ultra-high resolution chromosomal microarray analysis optimized for neurodevelopmental disorders of 10,351 consecutive
Burnside–Butler_syndrome
English molecular biologist
schools. These charities are financed using royalty income from licensing microarray technology. The Southern blot is used for DNA analysis and was routinely
Edwin_Southern
Glass colored with uranium oxide
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Uranium_glass
Symbols and abbreviations used in cytogenetics
bands (cytogenic coordinates). Microarray format, which is originally designed for copy number change detected by a microarray using the × (times) symbol
Cytogenetic_notation
Diagram in computational biology
two channel DNA microarray gene expression data, MA plots are also used to visualise high-throughput sequencing analysis. Microarray data is often normalized
MA_plot
Use of knowledge for practical goals
pharmaceutical drugs), and research (like interferon cloning and DNA microarrays). Complex manufacturing and construction techniques and organizations
Technology
Glass object created by dripping molten glass into cold water
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Prince_Rupert's_drop
American biochemist and immunologist
Director of the UCI Vaccine Research & Development Center and the Protein Microarray Laboratory and Training Facility. Felgner's work on cationic lipid-based
Philip_Felgner
selected wavelength. The beam of light hits the analyte in the spots of the microarrays and refracts. The mass of the analyte causes the angle of reflected light
CD/DVD_based_immunoassay
Chromosomal deletion syndrome
is confirmed by the detection of a deletion in the WHSCR. Chromosomal microarray and Cytogenetic analysis.D4S96 or D4Z1 chromosome band 4p16.3–specific
Wolf–Hirschhorn_syndrome
Lowering the temperature of a liquid below its freezing point without it becoming a solid
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Supercooling
Technology for screening small molecule compounds
using a fluorescent primer and hybridized onto the DNA-microarray slide. Afterwards, microarrays are analyzed using a laser scan and spot intensities detected
DNA-encoded_chemical_library
Melting points of chemical mixtures
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Liquidus_and_solidus
DNA technology
protein microarrays by performing in vitro synthesis of the target proteins from their DNA templates. This method of synthesizing protein microarrays overcomes
Cell-free_protein_array
American scientist and businessman
Brown is co-founder of the Public Library of Science, inventor of the DNA microarray, and a former investigator at Howard Hughes Medical Institute. Brown received
Patrick_O._Brown
Gene expression database
that provides information on gene expression patterns from RNA-Seq and Microarray studies, and protein expression from Proteomics studies. The Expression
Expression_Atlas
Australian statistician & academic
Australian statistician known for her work on variance reduction for microarrays, and for inferring proteins from mass spectrometry data. Yang is a Professor
Jean_Yang
DNA microarray (2008) allows for assay of approximately 500,000 polymorphisms in a single genome.
History_of_Tay–Sachs_disease
Iranian-American physician-scientist
microenvironments. Alizadeh is recognized for developing the Lymphochip microarray and for his early cancer molecular taxonomy work defining the molecular
Ash_Alizadeh
Software project for the analysis of genomic data
that are mainly, but not solely, oriented towards different types of microarrays. The project was started in the Fall of 2001 and is overseen by the Bioconductor
Bioconductor
Field of molecular biology
prior knowledge of what transcripts to study (as microarrays do). RNA sequencing has taken over microarray and SAGE technology in recent years, as noted
Functional_genomics
Defect in the structure of the heart that is present at birth
syndrome) Array comparative genomic hybridization (also known as chromosomal microarray analysis) Inherited protein-coding single nucleotide variant (SNV) or
Congenital_heart_defect
Material made by fusing powdered glass to a substrate by firing
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Vitreous_enamel
Molecular biology technique
of organisms. The general goal of the technique is similar to the DNA microarray. However, SAGE sampling is based on sequencing mRNA output, not on hybridization
Serial analysis of gene expression
Serial_analysis_of_gene_expression
Class of glasses based on fluorides rather than oxides
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Fluoride_glass
Protein found in humans
C4orf54 mRNA expression using microarray data on patients with normal tissues. The tissues with highest expression are from the cervix, lymph nodes, skin
Chromosome 4 open reading frame 54
Chromosome_4_open_reading_frame_54
Type of glass
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Soda–lime_glass
Sequencing of all the exons of a genome
financial factors. Two such technologies are microarrays and whole-genome sequencing.[citation needed] Microarrays use hybridization probes to test the prevalence
Exome_sequencing
Statistical method
analysis can be used for summarizing high-density oligonucleotide DNA microarrays data at probe level for Affymetrix GeneChips. In this case, the latent
Factor_analysis
Medical condition
dilation of the ascending aorta. The diagnosis is established by chromosomal microarray analysis detecting the duplication. There is no cure; treatment involves
7q11.23_duplication_syndrome
Process of compacting DNA molecules
Fluorescence, Pigment & Radioactivity High-throughput technique ("-omics") DNA microarray Mass spectrometry Lab-on-a-chip Gene regulation Epigenetic Genetic Post-transcriptional
DNA_condensation
Medical condition
diagnosis 48,XXXY is by chromosomal microarray showing the presence of extra X chromosomes. Chromosomal microarray (CMA) is used to detect extra or missing
XXXY_syndrome
Non-biological variation in the results of biological experiments
types of high-throughput sequencing experiments, including those using microarrays, mass spectrometers, and single-cell RNA-sequencing data. They are most
Batch_effect
Model organism database on Xenopus frogs
amenability to microinjection also makes them extremely well suited to microarray approaches. Furthermore, these same characteristics make Xenopus, one
Xenbase
Canadian statistician
penalization in regression and related problems, and Significance Analysis of Microarrays. Tibshirani was born on 10 July 1956 in Niagara Falls, Ontario, Canada
Robert_Tibshirani
Optical lenses that darken on exposure to certain wavelengths of light
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Photochromic_lens
Biostatistician
supervised and unsupervised machine learning, and related issues in microarray analysis". Tseng is leading a research group of Bioinformatics and Statistical
George_Tseng
Detection of mRNA molecules
technologies can be used to generate the necessary data to analyse. DNA microarrays measure the relative activity of previously identified target genes.
Gene_expression_profiling
American biostatistician
Kellie Jo Archer (born 1969) is a biostatistician specializing in microarray analysis techniques. She is a professor of biostatistics and chair of the
Kellie_Archer
are used in post-labeling of nucleic acids by fluorescence detection in microarray. They are reactive with N-Hydroxysuccinimide ester group which helps attach
Aminoallyl_nucleotide
Part of the genome still active in the time immediately following death
the concentration of a large number of different types of mRNA include microarrays and high-throughput sequencing via RNA-Seq. Analysis from a serology
Thanatotranscriptome
Brand of dish and other cookware pieces
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
CorningWare
Molecule that carries genetic information
study of crystal structures DNA Day – Holiday celebrated on April 25 DNA microarray – Collection of microscopic DNA spots attached to a solid surface DNA
DNA
Quantity divided by its original amount
larger". Fold change is often used in analysis of gene expression data from microarray and RNA-Seq experiments for measuring change in the expression level of
Fold_change
Molecular biology method
technology that combines chromatin immunoprecipitation ('ChIP') with DNA microarray ("chip"). Like regular ChIP, ChIP-on-chip is used to investigate interactions
ChIP-on-chip
Type of scatter plot
plots are also used to graphically display a significance analysis of microarrays (SAM) gene selection criterion, an example of regularization. The concept
Volcano_plot_(statistics)
Statistical method
recording into stratigraphic zones), in genetics (the problem of separating microarray data into similar copy-number regimes), and in biophysics (detecting state
Step_detection
Type of glass
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Crown_glass_(optics)
Data visualization technique
r-project.org. Retrieved 2025-04-23. "Using R to draw a heat map from Microarray Data". Molecular Organisation and Assembly in Cells. 26 Nov 2009. "Draw
Heat_map
World Community Grid volunteer computing subproject
project worked by identifying visual patterns in large numbers of tissue microarrays taken from archived tissue samples. By correlating the pattern data with
Help_Defeat_Cancer
American life sciences company
‹ The template below (Cite check) is being considered for merging with Verify sources. See templates for discussion to help reach a consensus. › Sequenom
Sequenom
Biotechnology company
Rodney Turner was succeeded by Albrecht Läufer. Ayoxxa's protein chip or microarray technology enables the detection of large number of diseases through the
Ayoxxa_Biosystems
Software for understanding biological data
computational biology and bioinformatics, including genomics, proteomics, microarrays, systems biology, evolution, and text mining. Prior to the emergence
Machine_learning_in_biology
Rare neurodevelopmental disorder
involves exome or genome sequencing, a targeted gene panel, or a chromosome microarray capable of detecting single‑nucleotide variants and larger deletions encompassing
Chopra–Amiel–Gordon_syndrome
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Chemically_strengthened_glass
American bioinformatician
focus began to shift to post-genomic applications, with an emphasis on microarray analysis. Using a combination of laboratory and computational approaches
John_Quackenbush
American biotech company
Affymetrix is now Applied Biosystems, a brand of DNA microarray products sold by Thermo Fisher Scientific that originated with an American biotechnology
Affymetrix
American academic
(2003). Improving the specificity of biological signal detection from microarray data (PhD thesis). Stanford University. ProQuest 305300710. Fogg, Christiana
Olga_Troyanskaya
Lab procedure detecting 5-methylcytosines in DNA
(PCR) performed under non-methylation-specific conditions (Figure 3). Microarray-based methods use PCR based on non-methylation-specific conditions also
Bisulfite_sequencing
Rare genetic disorder
syndrome is suspected, genetic testing typically includes chromosomal microarray analysis using SNP array or oligonucleotide—able to detect 1q42 microdeletions
Skraban–Deardorff_syndrome
Australian statistician at the Walter and Eliza Hall Institute of Medical Research
of variance and bioinformatics, and in particular to the analysis of microarray data. Terry Speed was born in Victor Harbor, in South Australia, and grew
Terry_Speed
Multinational biotechnology research organization
private companies and research institutes. It is a manufacturer of DNA microarrays and a provider of gene expression profiling and microRNA profiling services
Phalanx_Biotech_Group
American businessman and biotechnology entrepreneur
birth control pill, the nicotine patch, corticosteroids, and the DNA microarray. Zaffaroni was born on February 27, 1923, in Montevideo. Zaffaroni was
Alejandro_Zaffaroni
American biochemist (born 1946)
method for pulsed-field gel electrophoresis, and methods for analyzing microarray data. Chu received the Clinical Scientist Award for Translational Research
Gilbert_Chu
Rare genetic syndrome
terminal and interstitial deletions are too small. The availability of DNA microarray technology for revealing multiple genetic problems simultaneously has
22q13_deletion_syndrome
Opaque or translucent, milk white or colored glass
Anti-reflective coating Chemically strengthened glass Corrosion Dealkalization DNA microarray Hydrogen darkening Insulated glazing Porous glass Self-cleaning glass
Milk_glass
Oligo-designing software
species specific and taxa specific qPCR assays Microarrays: Designs species specific and taxa specific microarrays xMAP: Designs oligos for Direct Hybridization
AlleleID
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