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Hypothesis in cognitive neuroscience
The neuronal recycling hypothesis was proposed by Stanislas Dehaene in the field of cognitive neuroscience in an attempt to explain the underlying neural
Neuronal_recycling_hypothesis
Evolution-related timelines
cognitive neuroscientist Stanislas Dehaene, who proposed the neuronal recycling hypothesis as an explanation for the VWFA and the associations between
Evolution of human intelligence
Evolution_of_human_intelligence
adversity, such as the loss of a loved one. According to the psychic pain hypothesis, depression is analogous to physical pain in that it informs them that
Evolutionary approaches to depression
Evolutionary_approaches_to_depression
2000 book by Randy Thornhill and Craig T. Palmer
attachment Cinderella effect Cognitive development Education Neuronal recycling hypothesis Science of reading Language acquisition Personality development
A_Natural_History_of_Rape
Branch of psychology
intelligence Cooperative eye hypothesis Origin of language Origin of speech Social exchange theory Ovulatory shift hypothesis Neuroethology r/K selection
Evolutionary_psychology
Theories on the development of personality
attachment Cinderella effect Cognitive development Education Neuronal recycling hypothesis Science of reading Language acquisition Personality development
Personality_development
American psychologist
attachment Cinderella effect Cognitive development Education Neuronal recycling hypothesis Science of reading Language acquisition Personality development
David_P._Barash
Memetics – Study of self-replicating units of culture Multiple discovery – Hypothesis about scientific discoveries and inventions Universal Darwinism – Application
History of evolutionary psychology
History_of_evolutionary_psychology
Field of study
attachment Cinderella effect Cognitive development Education Neuronal recycling hypothesis Science of reading Language acquisition Personality development
Evolutionary educational psychology
Evolutionary_educational_psychology
Process of synapse elimination
believed that the purpose of synaptic pruning is to remove unnecessary neuronal structures from the brain; as the human brain develops, the need to understand
Synaptic_pruning
Protein found in humans
(aSyn) is a protein that in humans is encoded by the SNCA gene. It is a neuronal protein involved in the regulation of synaptic vesicle trafficking and
Alpha-synuclein
Chemical element with atomic number 82 (Pb)
be skipped depending on the material recycled and its potential contamination. Of the sources of lead for recycling, lead–acid batteries are the most important;
Lead
Form of neural negative feedback
neurotransmitters in the synapse, generally produced by persistent high frequency neuronal stimulation. The neurotransmitters are released by the synapse to propagate
Short-term synaptic depression
Short-term_synaptic_depression
Protein family
release of synaptic vesicles containing neurotransmitters in neurons. These neuronal SNAREs are the targets of the neurotoxins responsible for botulism and
SNARE_protein
Reabsorption of a neurotransmitter by a neurotransmitter transporter
is necessary for normal synaptic physiology because it allows for the recycling of neurotransmitters and regulates the level of neurotransmitter present
Reuptake
Mammalian protein found in humans
with certain isoforms preferentially expressed in neurons; changes in the neuronal ratio of these isoforms have been associated with Alzheimer's disease.
Amyloid-beta precursor protein
Amyloid-beta_precursor_protein
Dicarboxylic acid with pyridine backbone
microglia and macrophages. High levels of quinolinic acid can lead to hindered neuronal function or even apoptotic death. Quinolinic acid produces its toxic effect
Quinolinic_acid
Biological junctions through which neurons' signals can be sent
junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons
Chemical_synapse
Modifying synaptic strength via cell adhesion molecules
alignment of pre- and post-synaptic signal transduction pathways, vesicular recycling in regards to endocytosis and exocytosis, integration of postsynaptic
Synaptic_stabilization
Release of neurotransmitters in a synapse
has over full fusion: 1) kiss-and-run enables more efficient vesicle recycling, as the secretory vesicle's form remains stable and 2) kiss-and-run can
Kiss-and-run_fusion
Sterol biosynthesized by all animal cells
Hansen SB, Wang H (September 2023). "The shared role of cholesterol in neuronal and peripheral inflammation". Pharmacology & Therapeutics. 249 108486.
Cholesterol
Degradation of functioning of the brain
in the organism's abilities to handle calcium will ultimately influence neuronal firing and the ability to propagate action potentials, which in turn would
Aging_brain
Class of enzymes
information processing in neuronal cells. Overall, diacylglycerol and inositol triphosphate signaling has implications for neuronal plasticity, impacting
Inositol-phosphate phosphatase
Inositol-phosphate_phosphatase
Glycoprotein involved in neuronal migration
secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell
Reelin
Protein-coding gene in Homo sapiens
not function in recycling of vesicles but rather functions in the act of fusing vesicles with the plasma membrane. Because neuronal function depends
N-ethylmaleimide sensitive fusion protein
N-ethylmaleimide_sensitive_fusion_protein
Health crisis in 1990s
PrPRes, PrPD, or PrPBSE) accumulates in the brain, eventually leading to neuronal death and the formation of amyloid plaques. As a protein, the prion has
Mad_cow_crisis
Protein family
cytoskeleton rearrangement, cell motility, membrane protein trafficking and recycling, signal transduction and tissue compartmentalization have been explored
Fructose-bisphosphate aldolase
Fructose-bisphosphate_aldolase
Glutametergic neuronal junction that is typically inactive
hypotheses for the mechanisms of synapse silence: The "whispering synapse" hypothesis: A synapse that releases glutamate more slowly than normal, thus activating
Silent_synapse
Species of mushroom
metabotropic glutamate receptors which are involved in the control of neuronal activity. It is these interactions which are thought to cause the psychoactive
Amanita_muscaria
The ribbon synapse is a type of neuronal synapse characterized by the presence of an electron-dense structure, the synaptic ribbon, that holds vesicles
Ribbon_synapse
Chemical substance that enables neurotransmission
synaptic communication through astrocytic diffusion or gliotransmission. Neuronal activity triggers an increase in astrocytic calcium levels, prompting the
Neurotransmitter
Tropane alkaloid and stimulant drug
"Cocaine Blocks Effects of Hunger Hormone, Ghrelin, Via Interaction with Neuronal Sigma-1 Receptors". Molecular Neurobiology. 56 (2): 1196–1210. doi:10
Cocaine
Protein family
than would be possible by the SNARE-recycling model alone. Figure 1 summarizes the updated model of the SNARE hypothesis. The 20S complex is a known target
Soluble NSF attachment protein
Soluble_NSF_attachment_protein
Effects of pollution on the brain
increase oxidative stress and inflammation in the brain, resulting in neuronal damage. Meta-analysis suggests that NO2 is also related to depression,
Brain_health_and_pollution
Protein complexes which degrade ubiquitin-tagged proteins by proteolysis
Baumeister W, Fernández-Busnadiego R (8 February 2018). "In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment". Cell. 172 (4):
Proteasome
Protein-coding gene in the species Homo sapiens
monophosphate. These structural features underpin IMPA1's role in inositol recycling and its sensitivity to lithium inhibition, which occurs through competitive
Inositol_monophosphatase_1
Cell surface receptor found in humans
disease. In the brain, TLR4 is expressed by neurons as well as the non-neuronal glial cells, which include microglia, astrocytes, and oligodendrocytes
Toll-like_receptor_4
Enzyme
"Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease". PLOS Biology. 22 (7) e3002727. doi:10
Beta-secretase_1
Poisoning caused by lead in the body
the numbers of neurons, interferes with neurotransmission, and decreases neuronal growth. Lead ions (Pb2+), like magnesium ions (Mg2+), block NMDA receptors
Lead_poisoning
brain activity is a result of the neuronal usage that occurred during the previous waking hours. Essentially it is neuronal regeneration, activity that occurs
Sleep_and_memory
benefits. 9 January Scientists report studies that seem to support the hypothesis that life may have begun in a shallow lake rather than otherwise – perhaps
2024_in_science
Microscopic solid or liquid matter suspended in the Earth's atmosphere
neuroinflammation, oxidative stress, buildup of misfolded proteins, and neuronal cell death. In the gastrointestinal system, particulate matter is linked
Particulate_matter
Red pigment of the bile
particularly important in the brain, where it prevents excitotoxicity and neuronal death by scavenging superoxide during N-methyl-D-aspartic acid neurotransmission
Bilirubin
Chemical compound
be mimicked by IP3 and cADPR. For example, NAADP selectively stimulates neuronal differentiation, or exocytosis in cytotoxic T-cells. In contrast to IP3
Nicotinic acid adenine dinucleotide phosphate
Nicotinic_acid_adenine_dinucleotide_phosphate
Concept about individuals' intent and actions influencing those individuals' future
results in better emotional hygiene and reduced karmic impacts. Permanent neuronal changes within the amygdala and left prefrontal cortex of the human brain
Karma
Protein-coding gene in the species Homo sapiens, named for ketazocine
(MOR) contains a C-terminal LENL recycling motif that engages retromer complexes for rapid plasma membrane recycling, and the δ-opioid receptor (DOR)
Κ-opioid_receptor
Biological signaling using lipid molecules
"Distinct roles for ceramide and glucosylceramide at different stages of neuronal growth". J. Neurosci. 17 (9): 2929–2938. doi:10.1523/JNEUROSCI.17-09-02929
Lipid_signaling
Medical condition
including changes in the receptor conformation, changes in turnover, recycling, or production rates, degree of phosphorylation and receptor gene expression
Benzodiazepine withdrawal syndrome
Benzodiazepine_withdrawal_syndrome
Protein
transcription. This hypothesis is supported by the fact that SNX8 mainly colocalizes with Rab5 at early endosomes and partially with Rab4 at recycling endosomes
SNX8
Coenzyme
Shuttleworth CW, Yamboliev IA, Mutafova-Yambolieva VN (2012). "Release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide
Nicotinamide_adenine_dinucleotide
Study of organisms and their environment
ecology focuses on the ecology and evolution of "cognition" defined as the neuronal processes concerned with the acquisition, retention, and use of information
Ecology
Protein family
Aldahmesh MA, Al-Hassnan ZN, Aldosari M, Alkuraya FS (October 2009). "Neuronal ceroid lipofuscinosis caused by MFSD8 mutations: a common theme emerging"
Major_facilitator_superfamily
emissions reduction from increased adoption of metals recycling". Resources, Conservation and Recycling. 184 106424. Bibcode:2022RCR...18406424G. doi:10.1016/j
2022_in_science
Chemical compound
within the cell that contribute to dysfunction of neurons and eventual neuronal death. As a method of protein degradation within the cell, autophagy can
Bafilomycin
Cancer cells with features of normal cells
glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Cancer stem cells isolated from adult human gliomas were
Cancer_stem_cell
Overview of the events of 2020 in science
astronauts – on the lunar surface. Scientists report that carrion crows show a neuronal response that correlates with their perception of a stimulus, which they
July–September 2020 in science
July–September_2020_in_science
RNA species present outside of the cells in which they were transcribed
reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells". Nucleic Acids Research. 40 (21): 10937–49. doi:10.1093/nar/gks832
Extracellular_RNA
Human blood group classification
ligand binding and this led to the hypothesis that expression of DARC on the surface of erythrocytes, endothelial, neuronal cells and epithelial cells may
Duffy_antigen_system
Minogue G, Gill NP, Shepard RA, et al. (November 2022). "Integrity of Neuronal Size in the Entorhinal Cortex Is a Biological Substrate of Exceptional
Timeline_of_aging_research
"SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity". Science Advances. 9 (23) eadg2248. Bibcode:2023SciA
2023_in_science
Theories in cognitive psychology
to cognitive development. For example, increases in the myelination of neuronal axons, which protect the transmission of electrical signalling along the
Neo-Piagetian theories of cognitive development
Neo-Piagetian_theories_of_cognitive_development
report the direct visualization of neuronal tissue of extraordinarily well-preserved ≈2,000 years-old human neuronal tissue – whose discovery was reported
2020_in_science
"Immune cross-reactivity in celiac disease: anti-gliadin antibodies bind to neuronal synapsin I". J. Immunol. 178 (10): 6590–5. doi:10.4049/jimmunol.178.10
Gluten_immunochemistry
Enzyme found in humans
increasing Aβ degradation, preventing aggregation, and, ideally, preventing the neuronal loss that leads to disease symptoms. IDE was first identified by its ability
Insulin-degrading_enzyme
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NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
NEURONAL RECYCLING-HYPOTHESIS
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