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Metabolic reaction
Substrate-level phosphorylation is a metabolic reaction that results in the production of ATP or GTP supported by the energy released from another high-energy
Substrate-level phosphorylation
Substrate-level_phosphorylation
Process of releasing energy from nutrients using inorganic electron acceptors
third phosphate group to form ATP (adenosine triphosphate), by substrate-level phosphorylation, NADH and FADH2.[citation needed] The negative ΔG indicates
Cellular_respiration
Energy-carrying molecule in living cells
monophosphate (AMP). Other processes, such as oxidative phosphorylation or substrate-level phosphorylation, regenerate ATP. ATP is also a precursor to DNA and
Adenosine_triphosphate
Chemical process of introducing a phosphate
substrate-level phosphorylation during glycolysis and the Krebs cycle. By photophosphorylation in the chloroplasts of plant cells. Phosphorylation of
Phosphorylation
Chemical compound
ATP is achieved throughout processes such as substrate-level phosphorylation, oxidative phosphorylation, and photophosphorylation, all of which facilitate
Adenosine_diphosphate
Biochemical production of ethanol by yeast
appreciable amounts of ATP through substrate-level phosphorylation. This reduces the need of oxidative phosphorylation done by the TCA cycle via the electron
Crabtree_effect
Biochemical conversion of six-carbon sugars into acids in bacteria
molecules per molecule of glucose converted. ATP is generated by substrate-level phosphorylation. NADH is formed from the reduction of NAD. In the second stage
Mixed_acid_fermentation
Interconnected biochemical reactions releasing energy
membrane, reducing it to ubiquinol (QH2) which is a substrate of the electron transfer chain at the level of Complex III. For every NADH and FADH2 that are
Citric_acid_cycle
Metabolic redox process producing energy in the absence of oxygen
forms ATP which was catabolism that forms ATP through only substrate-level phosphorylation. Industrial fermentation is another type of fermentation that
Fermentation
Chemical compound
suggest that the substrate-level phosphorylation could potentially take place in aqueous prebiotic conditions. Acetyl Phosphate's phosphorylation process could
Acetyl_phosphate
Series of interconnected biochemical reactions
carboxylate group of the substrate, and one "catalytic" ion that participates in the dehydration. A final substrate-level phosphorylation now forms a molecule
Glycolysis
Salt formed from acetic acid and a base
converted into acetate in E. coli, whilst producing ATP by substrate-level phosphorylation. Acetate formation requires two enzymes: phosphate acetyltransferase
Acetate
Giant tube worm (species of annelid)
ATP (oxidative phosphorylation). Thus, ATP generated from oxidative phosphorylation and ATP produced by substrate-level phosphorylation become available
Riftia
Chemical compound
pyruvate kinase (PK) generates adenosine triphosphate (ATP) via substrate-level phosphorylation. ATP is one of the major currencies of chemical energy within
Phosphoenolpyruvic_acid
Group of organisms
aerobic respiration, anaerobic respiration, and fermentation (substrate-level phosphorylation) do not refer to primary nutritional groups, but simply reflect
Primary_nutritional_groups
Biochemical process involving the production of fats
activation by SREBP-1 through MAP-kinase-dependent phosphorylation regardless of changes in the mRNA levels. Along with insulin glucose also have been shown
Lipogenesis
Measure of energy in cells
produced by phosphorylation of ADP by the ATP synthase. ATP can also be produced by "substrate level phosphorylation" reactions (ADP phosphorylation by (1
Energy_charge
Biochemical pathways used by microbes to satisfy energy needs
respiration, ATP in fermentative organisms is produced by substrate-level phosphorylation where a phosphate group is transferred from a high-energy organic
Microbial_metabolism
Organism that ingests organic carbon for nutrition
with substrate-level phosphorylation and the production of end products (e.g. alcohol, CO2, sulfide). These products can then serve as the substrates for
Heterotroph
Naturally produced monosaccharide
(four ATP molecules are produced during glycolysis through substrate-level phosphorylation, but two are required by enzymes used during the process).
Glucose
Linked series of chemical reactions occurring within a cell
downregulating the movement of electrons through the ETC. The substrate-level phosphorylation that occurs at ATP synthase can also be directly inhibited
Metabolic_pathway
Respiration using electron acceptors other than oxygen
not use an electrochemical gradient but instead uses only substrate-level phosphorylation to produce ATP. The electron acceptor NAD+ is regenerated from
Anaerobic_respiration
Species of bacterium
ratio, accelerate fermentation, generate more ATP through the substrate-level phosphorylation, and accumulate more biomass. Lactiplantibacillus plantarum
Lactiplantibacillus_plantarum
Organic compound with a C=C–OH group
pyruvate kinase (PK) generates adenosine triphosphate (ATP) via substrate-level phosphorylation. Enediols are alkenes with a hydroxyl group on each carbon
Enol
Biological process that produces ethanol and carbon dioxide as by-products
are also converted to two ATP and two water molecules via substrate-level phosphorylation. Fermentation of sugar to ethanol and CO2 can also be done
Ethanol_fermentation
Protein found in humans
"Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2". Diabetologia. 55 (10): 2565–82
Insulin_receptor_substrate_1
Species of bacterium
acid cycle and oxidative phosphorylation by using different efficient strategies including redox balancing and substrate-level to survive the nutrient-limited
Treponema_pallidum
Species of bacterium
are absent, it is able to ferment arginine and pyruvate by substrate-level phosphorylation. Additionally, phenazines produced by P. aeruginosa can act
Pseudomonas_aeruginosa
Metabolic pathway
Oxidative phosphorylation or electron transport-linked phosphorylation or terminal oxidation, is the metabolic pathway in which cells use enzymes to oxidize
Oxidative_phosphorylation
Protein-coding gene in the species Homo sapiens
succinyl-CoA to succinate and Acetoacetyl CoA, accompanied by the substrate-level phosphorylation of ADP to ATP, as a step in the tricarboxylic acid (TCA) cycle
SUCLA2
Series of interconnected biochemical reactions
two molecules of lactate and use this reaction to perform substrate-level phosphorylation to make two molecules of ATP: Glucose + 2 ADP + 2 Pi → 2 Lactate
Lactic_acid_fermentation
Enzyme
diabetes similarly increases gluconeogenesis through enhanced uptake of substrate and increased flux through liver PC in mice and rats. Similarly to other
Pyruvate_carboxylase
Series of interconnected biochemical reactions
carboxylate group of the substrate, and one "catalytic" ion that participates in the dehydration. A final substrate-level phosphorylation now forms a molecule
Entner–Doudoroff_pathway
Chemical compound
3-phosphoglyceric acid in a coupled reaction producing two ATP via substrate-level phosphorylation. The single phosphate group left on the 3-PGA molecule then
3-Phosphoglyceric_acid
Process of introducing a phosphate group on to a protein
Protein phosphorylation is a reversible post-translational modification of proteins in which an amino acid residue is phosphorylated by a protein kinase
Protein_phosphorylation
British biochemist
substrate-level phosphorylation. Mitchell's chemiosmotic hypothesis was the basis for understanding the actual process of oxidative phosphorylation.
Peter_D._Mitchell
Protein-coding gene in the species Homo sapiens
succinyl-CoA to succinate and acetoacetyl CoA, accompanied by the substrate-level phosphorylation of GDP to GTP, as a step in the tricarboxylic acid (TCA) cycle
SUCLG2
streptomycin – structural biology – structural gene – substrate – substrate-level phosphorylation – surface area-to-volume ratio – symbiosis – symbiogenesis
Index_of_biology_articles
Species of bacterium
The conversion of acetyl-CoA to acetate mentioned above has substrate-level phosphorylation take place, giving another form of energy production without
Campylobacter_jejuni
Protein-coding gene in the species Homo sapiens
Wallberg-Henriksson H (June 2005). "Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects"
TBC1D4
Class of enzymes
which a nucleotide triphosphate (GTP or ATP) is formed by substrate-level phosphorylation. Research studies have shown that E. coli SCSs can catalyze
Succinyl coenzyme A synthetase
Succinyl_coenzyme_A_synthetase
Species of bacterium
sticklandii is achieved through substrate level phosphorylation, it can be achieved via electron-transport phosphorylation as well. The Rnf complex, a Na+-dependent
Acetoanaerobium_sticklandii
shifting of conformational states of the binding affinity to substrate. Phosphorylation is the addition of phosphate groups to proteins, which is the
Regulatory_enzyme
Genus of protists
also encodes for an elaborate anaerobic metabolism such as substrate-level phosphorylation and an ability to use fumarate as the terminal electron acceptor
Naegleria
Class of transport proteins
translocase during FOF1-ATPase reversal: critical role of matrix substrate-level phosphorylation". FASEB Journal. 24 (7): 2405–16. doi:10.1096/fj.09-149898
Adenine nucleotide translocator
Adenine_nucleotide_translocator
Species of fish parasite
prevalent in the genus Spironucleus. Hydrogenosomes produce ATP by substrate-level phosphorylation with hydrogen as a byproduct. Jørgensen A, Sterud E (2006)
Spironucleus_salmonicida
Protein-coding gene in humans
non-canonical (GST-β-catenin1-181) substrates (Xu et al., 2019). TV3 shows an increase of phosphorylation of both substrates compared to TV1 and TV2, which
CSNK1D
Family of enzymes
phosphates to protein substrates at serine, or threonine residues. This phosphorylation usually results in a change in activity of the substrate. Since PKAs are
Protein_kinase_A
Metabolic pathway involving both catabolism and anabolism
a net of only one NADPH produced and one ATP result (from substrate-level phosphorylation), and the former requires two ATP molecules to yield four ATP
Amphibolic
Protein-coding gene in the species Homo sapiens
glutamine. Mitochondrial succinyl-CoA is also essential for substrate-level phosphorylation in the TCA cycle, heme biosynthesis, ketone body utilization
ACSF3
Means by which some organisms create energy
different mechanisms: substrate-level phosphorylation, which is dependent on adenosine monophosphate (AMP), and oxidative phosphorylation independent of AMP
Microbial_oxidation_of_sulfur
Concept in genetics
the capacity for anaerobic metabolism through glycolysis and substrate-level phosphorylation, transamination of glutamyl-tRNA to glutaminyl-tRNA, lipid
Minimal_genome
Rare metabolic disease
glutamine. Mitochondrial succinyl-CoA is also essential for substrate-level phosphorylation in the TCA cycle, heme biosynthesis, ketone body utilization
Combined malonic and methylmalonic aciduria
Combined_malonic_and_methylmalonic_aciduria
Catabolic process in wide variety of organisms
later stages through the 'pay-off' phase of glycolysis through substrate-level phosphorylation to produce ATP and NADH. A range of bacteria can grow on sulfoquinovose
Sulfoglycolysis
Chemical compound (organic coenzyme)
bacteria and archaea so that electron transport phosphorylation and substrate-level phosphorylation can occur with increased efficiency. Butyryl-CoA
Butyryl-CoA
American neuroscientist
that succinyl phosphate is a transient intermediate in the substrate-level phosphorylation reaction, catalyzed by the enzyme succinyl-CoA synthetase,
John_Hildebrand
Post-translational carbohydrate modification of proteins
to protein phosphorylation in some respects. While there are roughly 500 kinases and 150 phosphatases that regulate protein phosphorylation in humans,
O-GlcNAc
Activation of a protein by exposure to its substrate
autophosphorylation, which triggers a subsequent phosphorylation cascade. This is a specific case where the substrate and the enzyme are the same molecule.[citation
Substrate_presentation
Response of fish to environmental hypoxia
metabolism occurs at the onset of hypoxia. Glycolysis and substrate-level phosphorylation are used as alternative pathways for ATP production. However
Hypoxia_in_fish
Large biological molecule that acts as a catalyst
consumed in the process. The molecules on which enzymes act are called substrates, which are converted into products. Nearly all metabolic processes within
Enzyme
Class of enzymes
C-terminal lobe (C-lobe) contains the phosphorylation site (T160 in CDK2) and serves as a binding platform for substrate proteins. The active site of a CDK
Cyclin-dependent_kinase
Branch of proteomics
containing a phosphate group as a posttranslational modification. Phosphorylation is a key reversible modification that regulates protein function, subcellular
Phosphoproteomics
Study of this residue has shown that phosphorylation promotes a conformational change that prevents ATP and substrate binding by steric interference with
Cyclin-dependent kinase complex
Cyclin-dependent_kinase_complex
Cell-cycle regulatory complex
into the ligase complex, instead of substrate phosphorylation. i.e.: The subunit, CDC20 allows APC to degrade substrates such as anaphase inhibitors (Pdsp1)
Anaphase-promoting_complex
Protein-coding gene in the species Homo sapiens
cap-dependent translation by binding to translation initiation factor eIF4E. Phosphorylation of 4E-BP1 results in its release from eIF4E, thereby allows cap-dependent
EIF4EBP1
P38 mitogen-activated protein kinases
as the activation dependent on two phosphorylation events, a three-tiered pathway architecture and similar substrate recognition sites. These are the "classical"
Mitogen-activated protein kinase
Mitogen-activated_protein_kinase
Biochemical process in which a phosphate group is removed from a molecule
to increase or reduce its activity. Phosphorylation and dephosphorylation can be used on all types of substrates, such as structural proteins, enzymes
Dephosphorylation
Series of biochemical reactions
domain of Akt, blocking its phosphorylation and activation. When the pathway is activated by insulin, insulin receptor substrate 1 (IRS-1) transcription is
Akt/PKB_signaling_pathway
Biosynthesis of glucose molecules
results in the biosynthesis of glucose from certain non-carbohydrate carbon substrates. It is a ubiquitous process, present in plants, animals, fungi, bacteria
Gluconeogenesis
Enzyme which catalyzes the removal of a phosphate group from a molecule
of its substrate, it is a subcategory of hydrolases. Phosphatase enzymes are essential to many biological functions, because phosphorylation (e.g. by
Phosphatase
Class of protein kinase enzymes
threonine side chain in proteins. This process is called phosphorylation. Protein phosphorylation in particular plays a significant role in a wide range
Serine/threonine-specific protein kinase
Serine/threonine-specific_protein_kinase
Protein-coding gene in the species Homo sapiens
its target substrate is the S6 ribosomal protein. Phosphorylation of S6 induces protein synthesis at the ribosome. The phosphorylation of p70S6K at
P70-S6_Kinase_1
Enzyme catalyzing transfer of phosphate groups onto specific substrates
that catalyzes the transfer of phosphate groups to substrates. This process is known as phosphorylation. Typically ATP is the phosphate donor. Kinases are
Kinase
Organelle-like structure in bacteria with a protein shell containing enzymes
phosphorylated acyl compound that can readily be a source of substrate-level phosphorylation or enter central metabolism, depending on if the organism is
Bacterial_microcompartment
Family of enzymes
proteins and subsequent NF-κB activation. However, the substrate proteins present for phosphorylation vary, since protein expression is different between
Protein_kinase_C
Class of enzymes
forming hexose phosphate. In most organisms, glucose is the most important substrate for hexokinases, and glucose-6-phosphate is the most important product
Hexokinase
Non-receptor tyrosine kinase and coding gene in humans
transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation". The Journal of Experimental Medicine. 193 (2): 263–9. doi:10
Janus_kinase_2
Family of heat shock proteins
is closed, and peptides are tightly bound to the substrate binding domain. Protein phosphorylation, a post-translational modification, helps to regulate
Hsp70
Defensive mechanism of cells against glycation
process involving the cross inhibition of glucose and fatty acids for substrates. It is theorized to play a role in explaining type 2 diabetes and insulin
Randle_cycle
Regulatory protein found in most eukaryotic tissues
ubiquitin: UBB, UBC, UBA52 and RPS27A. The addition of ubiquitin to a substrate protein is called ubiquitylation (or ubiquitination or ubiquitinylation)
Ubiquitin
Enzyme participating to the regulation of carbohydrate metabolism
Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. In medicine, the term is often used to refer
Glucokinase
Mammalian protein found in Homo sapiens
that phosphorylate a variety of target substrates (over 75 have been identified in budding yeast); phosphorylation of these proteins leads to cell cycle
Cyclin-dependent_kinase_1
Cell receptor found in humans
a binding site for the insulin receptor substrate (IRS-1), which is subsequently activated via phosphorylation. The activated IRS-1 initiates the signal
Insulin_receptor
Class of enzymes
Schiff base. Upon substrate binding, Lys-303 is displaced by the substrate's amine. This positions the carboxylate of the substrate within the active
Aromatic L-amino acid decarboxylase
Aromatic_L-amino_acid_decarboxylase
Set of three serine threonine-specific protein kinases
"SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity". Cell. 127 (1): 125–37. doi:10.1016/j.cell.2006
Protein_kinase_B
Protein found in humans
presence or absence of manganese (Mn2+). Autophosphorylation and substrate phosphorylation occurred when exposed to both Mn2+ and Mg2+. Mn2+ and was dose
Integrin-linked_kinase
Class of enzymes
GSK-3 phosphorylation is regulated by several factors. Phosphorylation of certain GSK-3 residues can increase or decrease its ability to bind substrate. Phosphorylation
GSK-3
Cdk1 phosphorylation site or only phosphoserines present, Cks1 is unable to properly bind to the substrate and promote Sic1 multi-phosphorylation. This
Sic1
priming of substrates by Plk itself or other kinases such as Cdk1 to create a docking site. However, there could also be phosphorylation-independent
Polo-like_kinase
Protein-coding gene in the species Homo sapiens
Dual specificity tyrosine-phosphorylation-regulated kinase 1A is an enzyme that in humans is encoded by the DYRK1A gene. Alternative splicing of this
DYRK1A
Class of enzymes
group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein
Protein_phosphatase
Chemical compound
phosphatase domains of PFK-2/FBPase-2 are active or inactive depends on the phosphorylation state of the enzyme. Fructose-6-p-phosphate is phosphorylated by the
Fructose_2,6-bisphosphate
Ability of biomolecules to bind specific ligands
ability of an enzyme to catalyze a given reaction, with the ligand as a substrate. If a given enzyme has a high chemical specificity, this means that the
Chemical_specificity
Signaling pathway involving transforming growth factor beta proteins
receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. Each class of ligand binds to a specific type
TGF_beta_signaling_pathway
Enzyme involved in glycogenolysis
the phosphorylation of glycogen phosphorylase by PhK involves the direct transfer of phosphate from adenosine triphosphate (ATP) to the substrate serine
Phosphorylase_kinase
Enzyme that regulates the metabolism of fatty acids
provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ACC can be controlled at the transcriptional level as well as by small
Acetyl-CoA_carboxylase
Bacterial metabolic pathway
phosphotransferase system (PTS) transports and phosphorylates its sugar substrates in a single energy-coupled step. This transport process is dependent on
PEP_group_translocation
Human biochemical pathway
"Molecular Mechanisms of Insulin Resistance: Serine Phosphorylation of Insulin Receptor Substrate-1 and Increased Expression of p85α: The Two Sides of
Insulin signal transduction pathway
Insulin_signal_transduction_pathway
is cholesterol dependent and regulates the proteins' function (e.g., substrate presentation). Cholesterol regulates the function of several membrane
Cholesterol_signaling
Set of chemical reactions in organisms
multiple levels of metabolic regulation. In intrinsic regulation, the metabolic pathway self-regulates to respond to changes in the levels of substrates or
Metabolism
SUBSTRATE LEVEL-PHOSPHORYLATION
SUBSTRATE LEVEL-PHOSPHORYLATION
Male
Yiddish
(לֶעמְל) Yiddish name LEMEL means "little lamb; meek."
Surname or Lastname
Jewish (Ashkenazic)
Jewish (Ashkenazic) : variant spelling of Levin.English, North German, and Dutch : from the Germanic personal name represented by Old English Lēofwine, Saxon Liafwin, composed of the elements lēof ‘dear’, ‘beloved’ + wine ‘friend’.English and Scottish : habitational name from places called Leven in East Yorkshire, Fife, and Renfrew. The first is probably from a stream name, possibly derived from a Celtic word meaning smooth (as in Welsh llyfyn). The Scottish place name is from a Gaelic river name meaning ‘elm river’.Dutch and North German : from a Flemish saint’s name, Lefwin (Lieven), the patron saint of Ghent (see Lewin 2).
Surname or Lastname
Jewish
Jewish : variant spelling of Levy.English : variant spelling of Leavey.
Surname or Lastname
English
English : variant spelling of Revell.French : habitational name from any of the places so named, for example in Isère and Haute-Garonne.French and southern French : nickname from Old French, Occitan reveau ‘rebel’.
Girl/Female
Muslim
Intelligent, Level headed
Surname or Lastname
English
English : from a late Old English personal name Lēofweald, composed of the elements lēof ‘dear’, ‘beloved’ + weald ‘power’, ‘rule’.French : variant spelling of Level.
Boy/Male
Muslim
Instrument to level something
Boy/Male
Japanese
Flat and level field.
Male
English
Variant spelling of English Lovell, LOVEL means "little wolf."
Boy/Male
Hebrew
United.
Boy/Male
Yiddish
Dearly loved.
Female
Greek
(ΣωστÏάτη) Feminine form of Greek Sostratos, SOSTRATE means "safe army."
Surname or Lastname
English
English : variant of Bevill.
Boy/Male
British, Christian, English, French
Little Wolf; Young Wolf
Girl/Female
Indian
Intelligent, Level headed
Boy/Male
Shakespearean
King Richard III' Lord Lovel.
Girl/Female
Arabic, Australian, Muslim
Level Headed; Intelligent
Surname or Lastname
English
English : variant spelling of Lovell.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : nickname for a fleet-footed or timid person, from Old French levre ‘hare’ (Latin lepus, genitive leporis). It may also have been a metonymic occupational name for a hunter of hares.English (of Norman origin) : topographic name for someone who lived in a place thickly grown with rushes, from Old English lǣfer ‘rush’, ‘reed’, ‘iris’. Compare Laver 3. Great and Little Lever in Greater Manchester (formerly in Lancashire) are named with this word (in a collective sense) and in some cases the surname may also be derived from these places.English (of Norman origin) : possibly from an unrecorded Middle English survival of an Old English personal name, Lēofhere, composed of the elements lēof ‘dear’, ‘beloved’ + here ‘army’.
Boy/Male
Indian, Tamil
High Level
SUBSTRATE LEVEL-PHOSPHORYLATION
SUBSTRATE LEVEL-PHOSPHORYLATION
Girl/Female
Hebrew
Joyous melody.
Surname or Lastname
English
English : variant of Saker.North German : habitational name for someone who lived in a damp place, a derivative of Seck 1.Jewish (Ashkenazic) : from Sack 1, with the agent suffix -er.
Boy/Male
Arabic
Justice
Girl/Female
Tamil
Tholakshi | தோலாகà¯à®·à¯€
Goddess Parvati (Wife of Lord Shiva)
Girl/Female
Hindu, Indian, Kannada, Telugu
Equal; One who Poses All Best Qualities
Boy/Male
Muslim
Intimacy. Companionship.
Male
Croatian
, twin.
Boy/Male
Tamil
Ebony, Strong, To worship, A sage
Girl/Female
Tamil
The earth
Female
English
From a French word used as a term of endearment, BIBI means "bauble, toy."
SUBSTRATE LEVEL-PHOSPHORYLATION
SUBSTRATE LEVEL-PHOSPHORYLATION
SUBSTRATE LEVEL-PHOSPHORYLATION
SUBSTRATE LEVEL-PHOSPHORYLATION
SUBSTRATE LEVEL-PHOSPHORYLATION
n.
A horizontal line or plane; that is, a straight line or a plane which is tangent to a true level at a given point and hence parallel to the horizon at that point; -- this is the apparent level at the given point.
a.
Coinciding or parallel with the plane of the horizon; horizontal; as, the telescope is now level.
pl.
of Substratum
n.
An approximately horizontal line or surface at a certain degree of altitude, or distance from the center of the earth; as, to climb from the level of the coast to the level of the plateau and then descend to the level of the valley or of the sea.
n.
A substratum.
n.
A uniform or average height; a normal plane or altitude; a condition conformable to natural law or which will secure a level surface; as, moving fluids seek a level.
n.
A measurement of the difference of altitude of two points, by means of a level; as, to take a level.
a.
Even; flat; having no part higher than another; having, or conforming to, the curvature which belongs to the undisturbed liquid parts of the earth's surface; as, a level field; level ground; the level surface of a pond or lake.
v. t.
To adjust or adapt to a certain level; as, to level remarks to the capacity of children.
a.
Well balanced; even; just; steady; impartial; as, a level head; a level understanding. [Colloq.]
v. i.
To be level; to be on a level with, or on an equality with, something; hence, to accord; to agree; to suit.
v. t.
To make level; to make horizontal; to bring to the condition of a level line or surface; hence, to make flat or even; as, to level a road, a walk, or a garden.
a.
Having the slant of a bevel; slanting.
v. t.
To bring to a lower level; to overthrow; to topple down; to reduce to a flat surface; to lower.
v. t.
Figuratively, to bring to a common level or plane, in respect of rank, condition, character, privilege, etc.; as, to level all the ranks and conditions of men.
v. t.
To attend the levee or levees of.