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Transcription factor
Transcription factor II E (TFIIE) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It is a tetramer
Transcription_factor_II_E
Protein complex
Transcription factor II H (TFIIH) is a multi-subunit protein complex involved in both the transcription of protein-coding genes and the nucleotide excision
Transcription_factor_II_H
General transcription factors
Transcription factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase
Transcription_factor_II_D
Mammalian protein found in Homo sapiens
Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)
Transcription_factor_II_B
Protein that regulates the rate of DNA transcription
molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information
Transcription_factor
Nuclear protein
Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. TFIIA is one of several general (basal)
Transcription_factor_II_A
General transcription initiation factor
Transcription factor II F (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. TFIIF is encoded
Transcription_factor_II_F
Proteins that bind DNA
WRKY transcription factors (pronounced ‘worky’) are proteins that bind DNA. They are transcription factors that regulate many processes in plants and
WRKY_transcription_factor
Class of protein transcription factors
General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific
General_transcription_factor
Topics referred to by the same term
Series by Aptera Motors Oflag II-E, a prisoner of war camp in Germany 2nd arrondissement of Paris Transcription Factor II E Twice exceptional, an individual
2E
Transcription is heterocatalytic function of DNA
and Pol III relative to Pol II, are homologous to Pol II transcription factors. Crystal structures of RNA polymerases I and II provide an opportunity to
Eukaryotic_transcription
Transcription factor
finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor effector-domains
Zinc finger transcription factor
Zinc_finger_transcription_factor
Form of eukaryotic RNA polymerase II
polymerase II, a subset of general transcription factors, and regulatory proteins known as SRB proteins[clarification needed]. RNA polymerase II (also called
RNA_polymerase_II_holoenzyme
Protein
elongation factor) is a four-subunit protein complex (NELF-A, NELF-B, NELF-C/NELF-D, and NELF-E) that negatively impacts transcription by RNA polymerase II (Pol
Negative_elongation_factor
Complex of proteins necessary for gene transcription in eukaryotes and archaea
the RNA polymerase II active site for transcription. The minimal PIC includes RNA polymerase II and six general transcription factors: TFIIA, TFIIB, TFIID
Transcription preinitiation complex
Transcription_preinitiation_complex
Protein-coding gene in the species Homo sapiens
Transcription factor Sp3 is a protein that in humans is encoded by the SP3 gene. This gene belongs to a family of Sp1 related genes that encode transcription
Transcription_factor_Sp3
Protein needed for initiation of transcription in prokaryotes
sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation
Sigma_factor
Control of DNA to RNA conversion in cells
biology. The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working
Transcriptional_regulation
Class of DNA-binding proteins that regulate gene transcription
Activating transcription factor, ATF, is a group of bZIP transcription factors, which act as homodimers or heterodimers with a range of other bZIP factors. First
Activating transcription factor
Activating_transcription_factor
Protein-coding gene in the species Homo sapiens
Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene
Transcription_factor_Sp1
Protein-coding gene in the species Homo sapiens
Transcription factor Sp2 is a protein that in humans is encoded by the SP2 gene. This gene encodes a member of the Sp subfamily of Sp/XKLF transcription
Sp2_transcription_factor
Protein-coding gene in the species Homo sapiens
Transcription factor MafA is a protein that in humans is encoded by the MAFA gene. It is a member of the Maf family of transcription factors. In addition
Transcription_factor_MafA
Transcription factor
The GATA transcription factor family consists of six DNA-binding proteins (GATA1-6) that regulate transcription of DNA due to their ability to bind to
GATA_transcription_factor
Family of proteins
A winged-helix transcription factor is a type of transcription factor that binds to DNA using a protein domain called a winged-helix domain. In some cases
Winged-helix transcription factors
Winged-helix_transcription_factors
Prokaryotic protein
A ρ factor (Rho factor) is a bacterial protein involved in the termination of transcription. Rho factor binds to the transcription terminator pause site
Rho_factor
Protein-coding gene in the species Homo sapiens
T-box transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription
T-box_transcription_factor_T
Protein-coding gene in the species Homo sapiens
Transcription factor Sp7, also called Osterix (Osx), is a protein that in humans is encoded by the SP7 gene. It is a member of the Sp family of zinc-finger
Sp7_transcription_factor
Enzyme that transcribes DNA to small RNAs
initiation of transcription by Pol III, unlike bacterial σ factors and most of the basal transcription factors for Pol II transcription. This leads to
RNA_polymerase_III
Family of intracellular transcription factors
the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects of cellular
STAT_protein
Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)
(AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and
AP-1_transcription_factor
Protein-coding gene in the species Homo sapiens
Transcription factor 15 (TCF-15) also known as Paraxis, is a protein that in humans is encoded by the TCF15 gene. Transcription factor 15 is found in the
Transcription_factor_15
Chemical compound
transcription elongation by RNA Polymerase II. Sensitivity to DRB is dependent on DRB sensitivity inducing factor (DSIF), negative elongation factor (NELF)
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole
Protein-coding gene in the species Homo sapiens
Transcription factor Sp8 also known as specificity protein 8 (SP-8) or Btd transcription factor (buttonhead) is a protein that in humans is encoded by
Sp8_transcription_factor
Molecular structure formed in DNA transcription
sequence, and transcription factor, including H3K27ac histone acetylation marks, SWI/SNF nucleosome remodeling, and TFIIH and sigma (σ) factors. While the
Transcription_bubble
Protein found in humans
ETS-related transcription factor Elf-3 is a protein that in humans is encoded by the ELF3 gene. It is a member of the ETS transcription factor family and
E74 like ETS transcription factor 3
E74_like_ETS_transcription_factor_3
Mammalian protein found in Homo sapiens
Transcription factor Jun, also known as c-Jun, is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms
Transcription_factor_Jun
Process of copying a segment of DNA into RNA
regulatory signals from enhancer DNA-bound transcription factors directly to the RNA polymerase II (pol II) enzyme bound to the promoter. Enhancers, when
Transcription_(biology)
Protein family
transformation-specific) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, 27 in the
ETS transcription factor family
ETS_transcription_factor_family
Protein-coding gene in the species Homo sapiens
Histone H4 transcription factor (or HiNF-P) is a protein that in humans is encoded by the HINFP gene (previously MIZF). HiNF-P/HINFP stand for "histone
Histone H4 transcription factor
Histone_H4_transcription_factor
Protein that controls rate of transcription of GH genes
positive transcription factor 1 (PIT1), POU domain, class 1, transcription factor 1 (POU1F1) and growth hormone factor 1 (GHF1), is a transcription factor for
Pituitary-specific positive transcription factor 1
Pituitary-specific_positive_transcription_factor_1
Section of nucleic acid sequence
termination factors. Release of the transcriptional complex frees RNA polymerase and related transcriptional machinery to begin transcription of new mRNAs
Terminator_(genetics)
Protein-coding gene in the species Homo sapiens
(TFIIE-beta), is a protein that in humans is encoded by the GTF2E2 gene. Transcription factor II E GRCh38: Ensembl release 89: ENSG00000197265 – Ensembl, May 2017
GTF2E2
Protein-coding gene in the species Homo sapiens
polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID)
TAF2
Type of non-coding RNA molecule
directly recruit RNA Pol II and general transcription factors and form the pre-initiation complex (PIC) prior to the transcription start site at the promoter
Enhancer_RNA
Protein signal which causes the release of transcribed RNA at a stop codon
biology, a termination factor is a protein that mediates the termination of RNA transcription by recognizing a transcription terminator and causing the
Termination_factor
Protein-coding gene in the species Homo sapiens
Transcription factor Sp4 is a protein that in humans is encoded by the SP4 gene. Sp4 transcription factor has been shown to interact with E2F1. GRCh38:
Sp4_transcription_factor
Region of non-coding DNA that regulates the transcription of neighboring genes
regulate. CREs typically regulate gene transcription by binding to transcription factors. A single transcription factor may bind to many CREs, and hence control
Cis-regulatory_element
Protein found in humans
COUP-TFII (COUP transcription factor 2), also known as NR2F2 (nuclear receptor subfamily 2, group F, member 2) is a protein that in humans is encoded by
COUP-TFII
Mammalian protein found in humans
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded
Microphthalmia-associated transcription factor
Microphthalmia-associated_transcription_factor
Mammalian protein found in Homo sapiens
Serum response factor, also known as SRF, is a transcription factor protein. Serum response factor is a member of the MADS (MCM1, Agamous, Deficiens,
Serum_response_factor
Protein-coding gene in the species Homo sapiens
transcription factor that binds to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start
TATA-binding_protein
Protein complex regulating transcription in eukaryotes
positive transcription elongation factor, P-TEFb, is a multiprotein complex that plays an essential role in the regulation of transcription by RNA polymerase
P-TEFb
Protein-coding gene in the species Homo sapiens
Calcium-responsive transcription factor (CaRF) is a protein that in humans is encoded by the CARF gene (formerly ALS2CR8). Knocking out the Carf (Als2cr8)
Calcium-responsive transcription factor
Calcium-responsive_transcription_factor
Protein-coding gene in the species Homo sapiens
Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 protein is a transcription factor that plays a role
ZEB2
Protein complex for mRNA transcription
kDa complex of 12 subunits, RNAP II is the most studied type of RNA polymerase. A wide range of transcription factors are required for it to bind to upstream
RNA_polymerase_II
Protein-coding gene in the species Homo sapiens
Transcription factor 4 (TCF-4) also known as immunoglobulin transcription factor 2 (ITF-2) is a protein that in humans is encoded by the TCF4 gene located
TCF4
DNA sequence that binds activators to increase the likelihood of gene transcription
the likelihood that transcription of a particular gene will occur. These proteins are usually referred to as transcription factors. Enhancers are cis-acting
Enhancer_(genetics)
Human protein-coding gene
TCEA1 gene. In other organisms, this gene is better known as transcription elongation factor II S (TFIIS). It mainly helps to resolve backtracked elongation
TCEA1
Group of proteins
Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA-binding domain is a POU domain
Octamer_transcription_factor
polymerase associated factor (PAF1) complex, which is involved in the transcription of DNA into mRNA through interaction with RNA Polymerase II. PAF1 is necessary
PAF1
Proteins that help regulate transcription
genetics, transcription coregulators are proteins that interact with transcription factors to either activate or repress the transcription of specific
Transcription_coregulator
Human protein and coding gene
(NRF2) or nuclear factor erythroid-derived 2-like 2 (NFE2L2), is a transcription factor that in humans is encoded by the NFE2L2 gene. NRF2 is a basic leucine
NFE2L2
Protein found in humans
RE1-Silencing Transcription factor (REST), also known as Neuron-Restrictive Silencer Factor (NRSF), is a protein which in humans is encoded by the REST
RE1-silencing transcription factor
RE1-silencing_transcription_factor
Protein domains
TBP-associated factors (TAF) are proteins that associate with the TATA-binding protein in transcription initiation. It is a part of the transcription initiation
TBP-associated_factor
Protein-coding gene in the species Homo sapiens
has been shown to interact with DLX5, CREB binding protein, Sp1 transcription factor, DLX2, TATA binding protein and Msh homeobox 2. LHX2, a LIMtype homeoprotein
Homeobox_protein_MSX-1
Protein-coding gene in the species Homo sapiens
Mitochondrial transcription factor A, abbreviated as TFAM or mtTFA, is a protein that in humans is encoded by the TFAM gene. This gene encodes a mitochondrial
TFAM
Protein-coding gene in the species Homo sapiens
kinase 7, E2F1, ERCC2, Estrogen receptor alpha, TCEA1, and XPB. Transcription Factor II H ENSG00000288114 GRCh38: Ensembl release 89: ENSG00000110768,
GTF2H1
Protein-coding gene in the species Homo sapiens
TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene. Initiation of transcription by RNA polymerase II requires the
TAF1
Protein-coding gene in the species Homo sapiens
PMID 26727489. S2CID 684842. "Entrez Gene: HSF1 heat shock transcription factor 1". Shamovsky I, Nudler E (March 2008). "New insights into the mechanism of heat
Heat_shock_factor_protein_1
Protein-coding gene in the species Homo sapiens
Upstream binding transcription factor (UBTF), or upstream binding factor (UBF), is a protein that in humans is encoded by the UBTF gene. In humans, the
UBTF
Antagonists of a youth's slang
Anti-sigma factors are small proteins that bind to sigma factors and inhibit transcriptional activity in regulating prokaryote gene expression. Anti-sigma
Anti-sigma_factors
DNA response element in some eukaryotes
recognized and bound by transcription factors to initiate gene transcription. Once the transcription factors bind to the promoters through the E-box, other enzymes
E-box
Enzyme in eukaryotes
RNA polymerase II RNA polymerase III Selective factor 1 Russell, Jackie; Zomerdijk, Joost C B M (2006). "The RNA polymerase I transcription machinery". Biochemical
RNA_polymerase_I
Transcription factor
Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the
CTCF
Transcriptional repressor protein
1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene. YY1 is a ubiquitously distributed transcription factor belonging
YY1
Protein-coding gene in the species Homo sapiens
polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID)
TAF9B
David Suter, Swiss cell biologist
chromatin accessibility by pluripotency transcription factors across the cell cycle". eLife. 8. doi:10.7554/eLife.50087. PMC 6890464. PMID 31794382. Strebinger
David_Suter_(biologist)
Protein that responds to low oxygen
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. They
Hypoxia-inducible_factor
Form of localized cell signaling
the SMAD family, which function as transcription factors. Specifically, the type I receptor, activated by the type II receptor, phosphorylates R-SMADs that
Paracrine_signaling
Protein-coding gene in humans
P300/CBP-associated factor (PCAF), also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and transcriptional coactivator associated with
PCAF
Protein-coding gene in the species Homo sapiens
Transcription initiation factor TFIID subunit 11 also known as TAFII28, is a protein that in humans is encoded by the TAF11 gene. Initiation of transcription
TAF11
Protein-coding gene found in humans
gene. It is a paired-type homeobox transcription factor weighing 27 kDa with 232 amino acids. Mixl1 transcription factor preferentially binds to the DNA
MIXL1
Transcription factor scaffold domain
trans-activating domain (TAD) is a transcription factor scaffold domain which contains binding sites for other proteins such as transcription coregulators. These binding
Transactivation_domain
Protein family
of Medicine Medical Subject Headings (MeSH) COUP+Transcription+Factor+II at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e
Chicken ovalbumin upstream promoter-transcription factor
Chicken_ovalbumin_upstream_promoter-transcription_factor
Protein-coding gene in the species Homo sapiens
Activating transcription factor 2, also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene. This gene encodes a transcription factor that
Activating transcription factor 2
Activating_transcription_factor_2
Protein-coding gene in the species Homo sapiens
S, Handa H (February 1998). "DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and
POLR2A
Protein-coding gene in the species Homo sapiens
MED21, POLR2A, Serum response factor TAF11, TAF1, TATA binding protein, and Transcription Factor II B. Transcription factor II F GRCh38: Ensembl release 89:
GTF2F1
Protein-coding gene in the species Homo sapiens
E74-like factor 1 (ets domain transcription factor) is a protein that in humans is encoded by the ELF1 gene. It was named for its similarity to E74, an
ELF1
Transcription factors
Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of
Hepatocyte_nuclear_factors
Type of CRISPR tool
spacer region can become possible targets. See: Transcriptional Activator, Transcription Factor Transcriptional Activators are protein domains or whole proteins
CRISPR_activation
Protein family
field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are
Mef2
Protein domain
a transcription factor Jun-B transcription factor CREB cAMP response element transcription factor OPAQUE2 (O2) transcription factor of the 22-kD zein
BZIP_domain
Nuclear receptors that bind to retinoids
receptors are type II nuclear receptors (a class of proteins) that bind to retinoids. When bound to a retinoid, they act as transcription factors, altering the
Retinoid_receptor
Protein-coding gene in the species Homo sapiens
functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes
TCEA2
Immune system messenger protein which induces inflammation
transcription is activated by a variety of signaling pathways and transcription factors, depending on the cell type and stimulus. TNF transcription does
Tumor_necrosis_factor
Protein-coding gene in humans
AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription factor, which
ATF1
Protein-coding gene in humans
Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the
RUNX2
Protein-coding gene in the species Homo sapiens
polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID)
TAF5
Protein-coding gene in the species Homo sapiens
has been shown to interact with TATA binding protein and TBPL1. Transcription Factor II A GRCh38: Ensembl release 89: ENSG00000165417 – Ensembl, May 2017
GTF2A1
recognized by the transcription factor II D (TFIID) subunits TAF6 and TAF9. It has been shown that DPE-dependent basal transcription depends highly on
Downstream_promoter_element
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TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
TRANSCRIPTION FACTOR-II-E
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