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EGF LIKE-DOMAIN

  • EGF-like domain
  • Protein domain

    The EGF-like domain is an evolutionary conserved protein domain, which derives its name from the epidermal growth factor where it was first described

    EGF-like domain

    EGF-like domain

    EGF-like_domain

  • Laminin
  • Protein in the extracellular matrix

    EGF LAG seven-pass G-type receptors (CELSR1, CELSR2, CELSR3), cysteine-rich with EGF-like domain proteins (CRELD1, CRELD2), multiple EGF-like domain proteins

    Laminin

    Laminin

    Laminin

  • Epidermal growth factor
  • Protein that stimulates cell division and differentiation

    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has 53

    Epidermal growth factor

    Epidermal growth factor

    Epidermal_growth_factor

  • Heparin-binding EGF-like growth factor
  • Protein-coding gene in the species Homo sapiens

    Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor

    Heparin-binding EGF-like growth factor

    Heparin-binding EGF-like growth factor

    Heparin-binding_EGF-like_growth_factor

  • Calcium-binding EGF domain
  • Protein domain

    calcium-binding EGF domain is an EGF-like domain of about forty amino-acid residues found in epidermal growth factor (EGF). This domain is present in a

    Calcium-binding EGF domain

    Calcium-binding EGF domain

    Calcium-binding_EGF_domain

  • MEGF6
  • Protein-coding gene in humans

    Multiple EGF like domains 6 is a protein that in humans is encoded by the MEGF6 gene. GRCh38: Ensembl release 89: ENSG00000162591 – Ensembl, May 2017 GRCm38:

    MEGF6

    MEGF6

    MEGF6

  • CRELD2
  • Protein-coding gene in the species Homo sapiens

    Cysteine-rich with EGF-like domain protein 2 is a protein that in humans is encoded by the CRELD2 gene found on chromosome 22q13. It is a known homolog

    CRELD2

    CRELD2

    CRELD2

  • SNED1
  • Extracellular matrix protein

    SNED1 (Sushi, Nidogen, and EGF-like Domains) is an extracellular matrix (ECM) protein expressed at low levels in a wide range of tissues. The gene encoding

    SNED1

    SNED1

  • Fibronectin type I domain
  • Protein family

    of the domain. In human tissue plasminogen activator chain A the FN1 domain together with the following epidermal growth factor (EGF)-like domain are involved

    Fibronectin type I domain

    Fibronectin type I domain

    Fibronectin_type_I_domain

  • Thrombomodulin
  • Mammalian protein found in humans

    tandemly repeated EGF-like domains, a Serine/Threonine-rich spacer and a transmembrane domain. It is a member of the C-type lectin domain (CTLD) group 14

    Thrombomodulin

    Thrombomodulin

    Thrombomodulin

  • EGF module-containing mucin-like hormone receptor
  • G protein-coupled receptor

    an extracellular epidermal growth factor (EGF)-like domain is fused to a GPCR domain through a mucin-like stalk. There are four variants of EMR labeled

    EGF module-containing mucin-like hormone receptor

    EGF_module-containing_mucin-like_hormone_receptor

  • Limulus clotting factor C
  • C-terminus, the domains are: EGF-like domain 3 Sushi domains one LCCL domain and one C-type lectin domain 2 more Sushi domains a trypsin domain This enzyme

    Limulus clotting factor C

    Limulus_clotting_factor_C

  • Factor VII
  • Mammalian protein found in humans

    of millions of times more fibrin molecules. Factor VII shares a common domain architecture with factors IX and X.[citation needed] The gene for factor

    Factor VII

    Factor VII

    Factor_VII

  • Protein S
  • Vitamin K-dependent plasma glycoprotein synthesized in the liver

    has a peptide between the Gla domain and the EGF-like domain, that is cleaved by thrombin. The Gla and EGF-like domains stay connected after the cleavage

    Protein S

    Protein S

    Protein_S

  • ADAM20
  • receptors. Disintegrin domains in ADAM proteins are approximately 90 amino acids in length. Cysteine-rich and EGF-like domains are extracellular modules

    ADAM20

    ADAM20

    ADAM20

  • Alliinase
  • Class of enzyme

    alliinases contain a novel N-terminal epidermal growth factor-like domain (EGF-like domain). Allyl (CH2=CH−CH2−S−) is prop-1-ene-2-yl, also known as propene-3-yl

    Alliinase

    Alliinase

    Alliinase

  • SCUBE1
  • Protein-coding gene in the species Homo sapiens

    Signal peptide, CUB domain and EGF like domain containing 1 is a protein that in humans is encoded by the SCUBE1 gene. This gene encodes a cell surface

    SCUBE1

    SCUBE1

    SCUBE1

  • EMR2
  • Protein-coding gene in the species Homo sapiens

    encoding EGF-like molecule containing mucin-like hormone receptor 3 EMR3 on chromosome 19. Like the related CD97 protein, the fourth EGF-like domain of EMR2

    EMR2

    EMR2

    EMR2

  • Diphtheria
  • Bacterial disease

    gains entry of DT into the host cell by binding to the EGF-like domain of heparin-binding EGF-like growth factor on the cell surface. This signals the cell

    Diphtheria

    Diphtheria

    Diphtheria

  • EMR1
  • Protein-coding gene in the species Homo sapiens

    family characterized by an extended extracellular region containing EGF-like domains. EMR1 is predominantly expressed on the surface of macrophages and

    EMR1

    EMR1

    EMR1

  • Pikachurin
  • Protein-coding gene in the species Homo sapiens

    Pikachurin, also known as AGRINL (AGRINL) and EGF-like, fibronectin type-III and laminin G-like domain-containing protein (EGFLAM), is a protein that in

    Pikachurin

    Pikachurin

    Pikachurin

  • CRELD1
  • Protein-coding gene in humans

    Cysteine-rich with EGF-like domain protein 1 is a protein that in humans is encoded by the CRELD1 gene. Epidermal growth factor (EGF)-like repeats are a class

    CRELD1

    CRELD1

    CRELD1

  • CD97
  • Mammalian protein found in humans

    EGF-like domains of CD97; chondroitin sulfate B with the fourth EGF-like domain; α5β1 and αvβ3 integrins with an RGD downstream the EGF-like domains;

    CD97

    CD97

    CD97

  • EGFL7
  • Protein-coding gene in the species Homo sapiens

    EGF-like domain-containing protein 7 is a protein that in humans is encoded by the EGFL7 gene. Intron 7 of EGFL7 hosts the miR-126 microRNA gene. Epidermal

    EGFL7

    EGFL7

    EGFL7

  • TIE1
  • Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 also known as TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1

    TIE1

    TIE1

    TIE1

  • MATH domain
  • Binding domain of TRAFs

    composed of five structural domains: an N-terminal endopeptidase domain, a MAM domain, a MATH domain, an EGF-like domain and a C-terminal transmembrane

    MATH domain

    MATH domain

    MATH_domain

  • Receptor tyrosine kinase
  • Class of enzymes

    transmembrane domain, as well as the non-receptor tyrosine kinases which do not possess transmembrane domains. The first RTKs to be discovered were the EGF and

    Receptor tyrosine kinase

    Receptor tyrosine kinase

    Receptor_tyrosine_kinase

  • NBPF26
  • Human gene

    560-1,581. Five EGF-like domains and one calcium-binding EGF-like domain are encoded in NBPF26. NBPF26 also encodes 13 Olduvai domains. Positions and sequences

    NBPF26

    NBPF26

    NBPF26

  • UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase
  • Class of enzymes

    Glcbeta-Ser53-EGF-like domain of bovine factor IX(45-87) ⇌ {\displaystyle \rightleftharpoons } UDP + Xylalpha(1-3)Glcbeta-Ser53-EGF-like domain of bovine

    UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase

    UDP-D-xylose:beta-D-glucoside_alpha-1,3-D-xylosyltransferase

  • Fibrillin-1
  • Protein found in humans

    The sequence of fibrillin-1 includes 47 six-cysteine EGF-like domains, 7 eight-cysteine domains homologous with latent TGF-beta binding protein, and a

    Fibrillin-1

    Fibrillin-1

    Fibrillin-1

  • TMEFF2
  • Protein-coding gene in the species Homo sapiens

    The Transmembrane protein with an EGF-like and two follistatin-like domains 2 (TMEFF2) gene is located on chromosome 2q32-q33 and encodes a 374-residue

    TMEFF2

    TMEFF2

    TMEFF2

  • Calcium-induced calcium release
  • Biological process

    sialophosphoprotein Osteopontin Secreted hormones Osteocalcin Calcium-binding domains C2 domain Cadherin C-type lectin EF hand EGF-like domain Gla domain

    Calcium-induced calcium release

    Calcium-induced_calcium_release

  • Neuregulin 1
  • Protein-coding gene in the species Homo sapiens

    factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like

    Neuregulin 1

    Neuregulin 1

    Neuregulin_1

  • Multiple epidermal growth factor-like domains 8
  • Protein-coding gene in the species Homo sapiens

    location and protein; not specified for MEGF8. Calcium EGF-like domain: Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular

    Multiple epidermal growth factor-like domains 8

    Multiple epidermal growth factor-like domains 8

    Multiple_epidermal_growth_factor-like_domains_8

  • Mucin
  • Glycoprotein

    11p15.5 in humans). The EGF-like domain containing mucins. These include MUC3(A,B), MUC4, MUC12, MUC13, and MUC17. Some EGF-like mucins, plus MUC1 and MUC16

    Mucin

    Mucin

    Mucin

  • EMI domain
  • Protein domain

    association with other domains, such as C1q, laminin-type EGF-like, collagen-like, FN3, WAP, ZP or FAS1. It has been suggested that the EMI domain could be a protein-protein

    EMI domain

    EMI_domain

  • Synaptotagmin
  • Protein family

    two C-terminal C2 domains - C2A and C2B. There are 17 isoforms in the mammalian synaptotagmin family. There are several C2-domain containing protein

    Synaptotagmin

    Synaptotagmin

    Synaptotagmin

  • Inositol trisphosphate
  • Chemical compound

    sialophosphoprotein Osteopontin Secreted hormones Osteocalcin Calcium-binding domains C2 domain Cadherin C-type lectin EF hand EGF-like domain Gla domain

    Inositol trisphosphate

    Inositol_trisphosphate

  • Cyclooxygenase
  • Class of enzymes

    proteins have three domains: an N-terminal EGF-like domain, a small 4-helical membrane anchor, and a core heme-peroxidase catalytic domain. Both form dimers

    Cyclooxygenase

    Cyclooxygenase

    Cyclooxygenase

  • Urokinase
  • Human protein

    three domains: the serine protease domain (consisting of residues 159–411), the kringle domain (consisting of residues 50-131), and the EGF-like domain (consisting

    Urokinase

    Urokinase

    Urokinase

  • Chromosome 22
  • Human chromosome

    Catechol-O-methyltransferase CRELD2: cysteine-rich with EGF-like domain protein 2 CSDC2: cold shock domain-containing protein D2 CSNK1E: encoding enzyme casein

    Chromosome 22

    Chromosome 22

    Chromosome_22

  • Cyclic ADP-ribose
  • Chemical compound

    cADPR, is a cyclic adenine nucleotide (like cAMP) with two phosphate groups present on 5' OH of the adenosine (like ADP), further connected to another ribose

    Cyclic ADP-ribose

    Cyclic ADP-ribose

    Cyclic_ADP-ribose

  • CRM197
  • Pharmaceutical compound

    "Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits

    CRM197

    CRM197

  • Complement component 1r
  • Protein-coding gene in humans

    (September 1987). "Identification of erythro-beta-hydroxyasparagine in the EGF-like domain of human C1r". FEBS Letters. 222 (1): 129–34. Bibcode:1987FEBSL.222

    Complement component 1r

    Complement component 1r

    Complement_component_1r

  • 3-Hydroxyasparagine
  • Chemical compound

    asparagine amino acid. It appears in posttranslational modification of cbEGF-like domains which can occur in humans and other Eukaryotes. The amino acid code

    3-Hydroxyasparagine

    3-Hydroxyasparagine

    3-Hydroxyasparagine

  • S100 protein
  • Family of vertebrate proteins involved in cell division and inflammation

    Chin (2014-08-01). "Structural Insights into Calcium-Bound S100P and the V Domain of the RAGE Complex". PLOS ONE. 9 (8) e103947. Bibcode:2014PLoSO...9j3947P

    S100 protein

    S100 protein

    S100_protein

  • Calreticulin
  • Soluble protein

    the DNA-binding domain of the superfamily of nuclear receptors. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid

    Calreticulin

    Calreticulin

    Calreticulin

  • Fibulin
  • Protein domain

    bulk of the remaining portion of the fibulin molecule is a series of nine EGF-like repeats. FBLN1, FBLN2, FBLN3, FBLN4, FBLN5, FBLN7 and HMCN1 is also known

    Fibulin

    Fibulin

    Fibulin

  • Protein domain
  • Self-stable region of a protein's chain that folds independently from the rest

    a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and folds independently from the rest. Each domain forms a compact

    Protein domain

    Protein domain

    Protein_domain

  • Animal model of schizophrenia
  • Area of study for clinical research

    knockout. One such mouse model is the heterozygous removal of the EGF-like domain on neuregulin 1, these models are called Nrg1(ΔEGF)+/− mice. Nrg1(ΔEGF)+/−

    Animal model of schizophrenia

    Animal model of schizophrenia

    Animal_model_of_schizophrenia

  • STAB1
  • Protein-coding gene in the species Homo sapiens

    fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The

    STAB1

    STAB1

    STAB1

  • Calmodulin
  • Messenger protein

    "Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains". Nature Structural Biology. 8 (11): 990–7. doi:10.1038/nsb1101-990

    Calmodulin

    Calmodulin

    Calmodulin

  • Annexin
  • Protein family

    consist of annexin with other domains like gelsolin. The basic structure of an annexin is composed of two major domains. The first is located at the COOH-terminal

    Annexin

    Annexin

    Annexin

  • Wall-associated kinase
  • Protein family

    kinase domain OsWAK-RLPs (receptor-like proteins)- Contain only the extracellular EGF-like domains OsWAK short genes- lacking both the domains but has

    Wall-associated kinase

    Wall-associated kinase

    Wall-associated_kinase

  • Selectin
  • Family of cell adhesion molecules

    structure: an N-terminal, calcium-dependent lectin domain, an epidermal growth factor (EGF)-like domain, a variable number of consensus repeat units (2,

    Selectin

    Selectin

    Selectin

  • CELSR3
  • Protein-coding gene in the species Homo sapiens

    contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand

    CELSR3

    CELSR3

    CELSR3

  • Ryanodine receptor
  • Class of intracellular transport proteins

    receptors, approximately 80% of the mass, are present in the cytosolic domain, which accounts for the many regulatory interactions. The cytosolic portion

    Ryanodine receptor

    Ryanodine receptor

    Ryanodine_receptor

  • Factor X
  • Mammalian protein found in Homo sapiens

    frequent mutation (Ser334Pro) in the catalytic domain and a substitution (Glu102Lys) in the second EGF-like domain". British Journal of Haematology. 90 (4):

    Factor X

    Factor X

    Factor_X

  • Calsequestrin
  • Calcium-binding protein

    for its high-capacity to bind Ca2+. In addition, the hydrophobic core of domain II appears to be necessary for CASQ2's function, because a single amino

    Calsequestrin

    Calsequestrin

    Calsequestrin

  • Neuregulin 3
  • Protein-coding gene in Homo sapiens

    superfamily of epidermal growth factor, EGF like polypeptide growth factor. These groups of proteins possess an 'EGF-like domain' that consists of six cysteine

    Neuregulin 3

    Neuregulin 3

    Neuregulin_3

  • Low-density lipoprotein receptor-related protein 8
  • Cell surface receptor found in humans

    binding domain of eight ligand binding regions, an EGF-like domain containing three cysteine-rich repeats, an O-linked glycosylation domain of 89 amino

    Low-density lipoprotein receptor-related protein 8

    Low-density lipoprotein receptor-related protein 8

    Low-density_lipoprotein_receptor-related_protein_8

  • Calcium signaling
  • Intracellular communication process

    channels for short term changes (like changes to electrochemical gradients) in the cell. For longer-term changes (like changes in gene transcription),

    Calcium signaling

    Calcium signaling

    Calcium_signaling

  • Tissue-type plasminogen activator
  • Protein involved in the breakdown of blood clots

    of novel tPA- and plasminogen-binding sites within fibrin(ogen) alpha C-domains". Biochemistry. 40 (3): 801–8. doi:10.1021/bi001789t. PMID 11170397. Ichinose

    Tissue-type plasminogen activator

    Tissue-type plasminogen activator

    Tissue-type_plasminogen_activator

  • Factor IX
  • Protein involved in coagulation

    structure of the two EGF domains and the trypsin-like domain was determined for the pig protein. The structure of the Gla domain, which is responsible

    Factor IX

    Factor IX

    Factor_IX

  • CELSR2
  • Protein-coding gene in humans

    contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand

    CELSR2

    CELSR2

    CELSR2

  • Protein C
  • Mammalian protein found in Homo sapiens

    in multiple domains: one Gla domain (residues 43–88); a helical aromatic segment (89–96); two epidermal growth factor (EGF)-like domains (97–132 and 136–176);

    Protein C

    Protein C

    Protein_C

  • Calcium-binding protein
  • role in many cellular processes. Calcium-binding proteins have specific domains that bind to calcium and are known to be heterogeneous. One of the functions

    Calcium-binding protein

    Calcium-binding protein

    Calcium-binding_protein

  • EMR3
  • Protein-coding gene in the species Homo sapiens

    EGF-like module-containing mucin-like hormone receptor-like 3 is a protein encoded by the ADGRE3 gene. EMR3 is a member of the adhesion GPCR family. Adhesion

    EMR3

    EMR3

    EMR3

  • Adhesion G protein-coupled receptor
  • Class of 33 human protein receptors

    Adhesion GPCRs get their name from their N-terminal domains that have adhesion-like domains, such as EGF, and the belief that they interact cell to cell and

    Adhesion G protein-coupled receptor

    Adhesion G protein-coupled receptor

    Adhesion_G_protein-coupled_receptor

  • FBLN5
  • Protein-coding gene in the species Homo sapiens

    protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins

    FBLN5

    FBLN5

    FBLN5

  • FBLN1
  • Protein-coding gene in the species Homo sapiens

    to fibrinogen. Fibulin-1 has modular domain structure and includes a series of nine epidermal growth factor-like modules followed by a fibulin-type module

    FBLN1

    FBLN1

    FBLN1

  • P-selectin
  • Type-1 transmembrane protein

    different domains like other selectin types; a C-type lectin-like domain in the N-terminus, an EGF-like domain and a complement-binding protein-like domains (same

    P-selectin

    P-selectin

    P-selectin

  • Calpain
  • Protease enzyme present in mammals and other organisms

    sialophosphoprotein Osteopontin Secreted hormones Osteocalcin Calcium-binding domains C2 domain Cadherin C-type lectin EF hand EGF-like domain Gla domain

    Calpain

    Calpain

    Calpain

  • Annexin A1
  • Protein-coding gene in the species Homo sapiens

    DD (January 1996). "Calcium-dependent binding of S100C to the N-terminal domain of annexin I". The Journal of Biological Chemistry. 271 (2): 719–725. doi:10

    Annexin A1

    Annexin A1

    Annexin_A1

  • LDL receptor
  • Mammalian protein found in Homo sapiens

    functionally distinct domains, including 3 EGF-like domains, 7 LDL-R class A domains, and 6 LDL-R class B repeats. The N-terminal domain of the LDL receptor

    LDL receptor

    LDL receptor

    LDL_receptor

  • Calbindin
  • Protein

    the CALB1 gene. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that have lost their calcium-binding capacity. Calbindin acts

    Calbindin

    Calbindin

    Calbindin

  • Osteocalcin
  • Mammalian protein found in humans

    first identified as a calcium-binding protein. Because osteocalcin has gla domains, its synthesis is vitamin K2–dependent. In humans, osteocalcin is encoded

    Osteocalcin

    Osteocalcin

    Osteocalcin

  • Phospholamban
  • Mammalian protein found in Homo sapiens

    NM, Kurzydlowski K, Tada M, MacLennan DH (August 2001). "Phospholamban domain IB forms an interaction site with the loop between transmembrane helices

    Phospholamban

    Phospholamban

    Phospholamban

  • MEGF10
  • Protein-coding gene in the species Homo sapiens

    Multiple EGF-like-domains 10 is a protein that in humans is encoded by the MEGF10 gene. MEGF10 is a regulator of satellite cell myogenesis and interacts

    MEGF10

    MEGF10

    MEGF10

  • PGAP6
  • Protein-coding gene in the species Homo sapiens

    contains an EGF-like domain, which is a sequence of about thirty to forty amino-acid residues, found in the sequence of epidermal growth factor (EGF), that

    PGAP6

    PGAP6

    PGAP6

  • C-type lectin
  • Protein domain

    PMID 24032031. Zelensky AN, Gready JE (December 2005). "The C-type lectin-like domain superfamily". FEBS J. 272 (24): 6179–217. doi:10.1111/j.1742-4658.2005

    C-type lectin

    C-type lectin

    C-type_lectin

  • ADAM17
  • Protein found in humans

    includes a pro-domain, a metallo-protease domain, a disintegrin domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic

    ADAM17

    ADAM17

    ADAM17

  • FBLN2
  • Protein-coding gene in the species Homo sapiens

    expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding". The Journal of Cell

    FBLN2

    FBLN2

    FBLN2

  • Borrelia burgdorferi
  • Species of bacteria

    Sonenshine, Daniel E.; Pal, Utpal (17 March 2021). "Antibodies against EGF-like domains in Ixodes scapularis BM86 orthologs impact tick feeding and survival

    Borrelia burgdorferi

    Borrelia burgdorferi

    Borrelia_burgdorferi

  • Hippocalcin
  • Protein found in humans

    sialophosphoprotein Osteopontin Secreted hormones Osteocalcin Calcium-binding domains C2 domain Cadherin C-type lectin EF hand EGF-like domain Gla domain

    Hippocalcin

    Hippocalcin

    Hippocalcin

  • Neuronal calcium sensor
  • which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin, GCAP, neurocalcin, visinin etc. All the members

    Neuronal calcium sensor

    Neuronal_calcium_sensor

  • Osteonectin
  • Mammalian protein found in Homo sapiens

    broken into 4 domains: 1) a Ca2+ binding domain near the glutamic acid-rich region at the amino terminus (domain I), 2) a cysteine-rich domain (II), 3) a

    Osteonectin

    Osteonectin

    Osteonectin

  • Calretinin
  • Protein found in humans

    troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions

    Calretinin

    Calretinin

    Calretinin

  • Calnexin
  • Mammalian protein found in humans

    (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic

    Calnexin

    Calnexin

    Calnexin

  • S100G
  • Protein-coding gene in the species Homo sapiens

    sialophosphoprotein Osteopontin Secreted hormones Osteocalcin Calcium-binding domains C2 domain Cadherin C-type lectin EF hand EGF-like domain Gla domain

    S100G

    S100G

    S100G

  • Aggrecan
  • Protein that in humans is encoded by the ACAN gene

    structural motifs, such as EGF-like domains, carbohydrate recognition domains (CRD), complement binding protein (CBP)-like domains, immunoglobulin folds and

    Aggrecan

    Aggrecan

    Aggrecan

  • Reelin
  • Glycoprotein involved in neuronal migration

    repeat into two subrepeats, A (the BNR/Asp-box repeat) and B (the EGF-like domain). Despite this interruption, the two subdomains make direct contact

    Reelin

    Reelin

    Reelin

  • EFEMP2
  • Protein-coding gene in the species Homo sapiens

    have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation

    EFEMP2

    EFEMP2

    EFEMP2

  • Temptin
  • Aplysia californica has sequence homology to epidermal growth factor (EGF)-like domains of higher organisms that mediate protein surface contact with cells

    Temptin

    Temptin

  • ADAM15
  • Protein-coding gene in humans

    functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as an EGF-like domain. Through its disintegrin-like domain

    ADAM15

    ADAM15

    ADAM15

  • Annexin A5
  • Protein-coding gene in the species Homo sapiens

    fluorescence microscope. Annexin A5 has been shown to interact with Kinase insert domain receptor and Integrin, beta 5. GRCh38: Ensembl release 89: ENSG00000164111

    Annexin A5

    Annexin A5

    Annexin_A5

  • Nicotinic acid adenine dinucleotide phosphate
  • Chemical compound

    two domains (an N-terminus LSm domain and a C-terminus anticodon-binding [AD] domain), LSm12 mediates NAADP activation of TPCs via its LSm domain. This

    Nicotinic acid adenine dinucleotide phosphate

    Nicotinic acid adenine dinucleotide phosphate

    Nicotinic_acid_adenine_dinucleotide_phosphate

  • Betacellulin
  • Protein-coding gene in humans

    the 65-105 amino acids are responsible for the EGF-like domain (Figure 2, exon 3), the transmembrane domain is from amino acids 119-139 (Figure 2, exon 4)

    Betacellulin

    Betacellulin

    Betacellulin

  • VWA2
  • Protein

    factor A-like (VWA) domain containing protein superfamily and consists of three VWA-like domains, two EGF-like domains, a cysteine-rich domain and a unique

    VWA2

    VWA2

    VWA2

  • Sarcalumenin
  • Protein-coding gene in the species Homo sapiens

    sialophosphoprotein Osteopontin Secreted hormones Osteocalcin Calcium-binding domains C2 domain Cadherin C-type lectin EF hand EGF-like domain Gla domain

    Sarcalumenin

    Sarcalumenin

    Sarcalumenin

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EGF LIKE-DOMAIN

  • Mike
  • Boy/Male

    Hebrew American English

    Mike

    Who is like God? Gift from God. In the Bible, St. Michael was the conqueror of Satan and patron...

    Mike

  • SIKE
  • Male

    Native American

    SIKE

    Native American Navajo name SIKE means "he sits at home."

    SIKE

  • MIKE
  • Male

    English

    MIKE

    Pet form of English Michael, MIKE means "who is like God?"

    MIKE

  • LIBE
  • Female

    Yiddish

    LIBE

    (לִיבֶּע) Yiddish form of German liebe, LIBE means "love." Compare with another form of Libe.

    LIBE

  • LISE
  • Female

    Norwegian

    LISE

    Danish and Norwegian form of German Liese, LISE means "God is my oath." Compare with masculine Lise.

    LISE

  • LAKE
  • Male

    English

    LAKE

    English name derived from the vocabulary word, from Latin lacus, LAKE means "pond, lake."

    LAKE

  • ÉVIKE
  • Female

    Hungarian

    ÉVIKE

    Hungarian pet form of Greek Eva, ÉVIKE means "life."

    ÉVIKE

  • RIKE
  • Female

    German

    RIKE

    Short form of German Friederike, RIKE means "peaceful ruler."

    RIKE

  • Lime
  • Surname or Lastname

    English

    Lime

    English : metonymic occupational name for a lime burner or for a whitewasher, from Old English līm ‘lime’.

    Lime

  • Jansi
  • Girl/Female

    Assamese, Bengali, Gujarati, Hindu, Indian, Kannada, Sindhi, Tamil, Telugu

    Jansi

    Life-like

    Jansi

  • Line
  • Surname or Lastname

    English

    Line

    English : from the medieval female personal name Line, a reduced form of Cateline (see Catlin) and of various other names, such as Emmeline and Adeline, containing the Anglo-Norman French diminutive suffix -line (originally a double diminutive, composed of the elements -el and -in).French (Liné) : metonymic occupational name for a linen weaver or a linen merchant, from an Old French adjective liné ‘made of linen’.

    Line

  • IKE
  • Male

    English

    IKE

    Pet form of English Isaac, IKE means "he will laugh."

    IKE

  • Nike
  • Girl/Female

    Greek

    Nike

    In Greek mythology Nike was the goddess of victory.

    Nike

  • Lake
  • Surname or Lastname

    English (chiefly West Country)

    Lake

    English (chiefly West Country) : topographic name for someone who lived by a stream, Old English lacu, or a habitational name from a place named with this word, for example in Wiltshire and Devon. Modern English lake (Middle English lake) is only distantly related, if at all; it comes via Old French from Latin lacus. This meaning, which ousted the native sense, came too late to be found as a place name element, but may lie behind some examples of the surname.Part translation of French Beaulac.

    Lake

  • LISE
  • Male

    Native American

    LISE

    Native American Miwok name LISE means "salmon head rising above water." Compare with feminine Lise.

    LISE

  • LUKE
  • Male

    English

    LUKE

    Anglicized form of Greek Loukas (Latin Lucas), LUKE means "from Lucania," a region of southern Italy. Lucania probably comes from the word lux, meaning "light." In the bible, this is the name of a Gentile Christian who was a companion of Paul. 

    LUKE

  • LIKO
  • Male

    Hawaiian

    LIKO

    Hawaiian name LIKO means "bud."

    LIKO

  • LIBE
  • Female

    Hebrew

    LIBE

    (לִיבֶּע) Hebrew name derived from the word lev, LIBE means "heart." Compare with another form of Libe.

    LIBE

  • Mike
  • Boy/Male

    American, Australian, British, Chinese, Christian, Danish, Dutch, English, French, German, Hebrew, Irish, Italian, Jamaican, Swedish, Swiss

    Mike

    Who is Like God; Form of Michael

    Mike

  • Lake
  • Boy/Male

    Australian, British, Christian, English

    Lake

    Pond; Lake

    Lake

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Online names & meanings

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EGF LIKE-DOMAIN

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EGF LIKE-DOMAIN

  • Like
  • a.

    To liken; to compare.

  • Liken
  • a.

    To make or cause to be like.

  • Liked
  • imp. & p. p.

    of Like

  • Like
  • a.

    In a manner like that of; in a manner similar to; as, do not act like him.

  • Liken
  • a.

    To allege, or think, to be like; to represent as like; to compare; as, to liken life to a pilgrimage.

  • Like
  • n.

    A liking; a preference; inclination; -- usually in pl.; as, we all have likes and dislikes.

  • Like
  • v. i.

    To come near; to avoid with difficulty; to escape narrowly; as, he liked to have been too late. Cf. Had like, under Like, a.

  • Like
  • a.

    In a like or similar manner.

  • Elf
  • v. t.

    To entangle mischievously, as an elf might do.

  • Line
  • v. t.

    To read or repeat line by line; as, to line out a hymn.

  • Snail-like
  • a.

    Like or suiting a snail; as, snail-like progress.

  • Live
  • v. i.

    To be maintained in life; to acquire a livelihood; to subsist; -- with on or by; as, to live on spoils.

  • Live
  • v. t.

    To spend, as one's life; to pass; to maintain; to continue in, constantly or habitually; as, to live an idle or a useful life.

  • Ylike
  • a. & adv.

    Like; alike.

  • Like
  • superl.

    Equal, or nearly equal; as, fields of like extent.

  • Like
  • superl.

    Inclined toward; disposed to; as, to feel like taking a walk.

  • Live
  • n.

    Life.

  • Ooidal
  • a.

    Shaped like an egg.

  • Egg
  • n.

    Anything resembling an egg in form.

  • Like
  • superl.

    Having the same, or nearly the same, appearance, qualities, or characteristics; resembling; similar to; similar; alike; -- often with in and the particulars of the resemblance; as, they are like each other in features, complexion, and many traits of character.