AI & ChatGPT searches , social queries for NATURE METHODS
Search references for NATURE METHODS. Phrases containing NATURE METHODS
See searches and references containing NATURE METHODS!
Search references for NATURE METHODS. Phrases containing NATURE METHODS
See searches and references containing NATURE METHODS!NATURE METHODS
Academic journal
Methods". Nature Protocols Bioinformatics List of scientific journals in biology ISCB Bioinformatics Core Competencies "For Authors : Nature Methods"
Nature_Methods
Scientific journal
October 28, 2025. "Nature Reviews Methods Primers: About the Editors". nature.com. Retrieved October 28, 2025. "Nature Reviews Methods Primers". MIAR: Information
Nature Reviews Methods Primers
Nature_Reviews_Methods_Primers
Lab technique in cellular biology
sequencing-based methods. These progressed from Sanger sequencing of Expressed sequence tag libraries, to chemical tag-based methods (e.g., serial analysis
RNA-Seq
Examines sequence information from individual cells
sequencing". Nature Methods. 11 (1): 18. doi:10.1038/nmeth.2771. PMID 24524131. S2CID 5252333. "Method of the year 2013". Nature Methods. 11 (1): 1. January
Single-cell_sequencing
Range of methods designed for assigning cell types
Visible Embryo Project Spatial biology "Method of the Year 2020: spatially resolved transcriptomics". Nature Methods. 18 (1): 1. January 2021. doi:10
Spatial_transcriptomics
Proposed hypothetical arcology
ultra-modern and technological living and interaction with wildlife and nature. Methods of transportation within the X-Seed would most likely include Maglev
X-Seed_4000
Controlling biological cells with light
with light". Nature Methods. 8 (1): 24–25. doi:10.1038/nmeth.f.323. S2CID 5808517. Editorial: "Method of the Year 2010". Nature Methods. 8 (1): 1. 2010
Optogenetics
British scientific journal
journals, including Nature Neuroscience, Nature Biotechnology, Nature Methods, the Nature Clinical Practice series of journals, Nature Structural & Molecular
Nature_(journal)
Electron microscopy technique
structure determination of biomolecules in solution." Nature Methods also named cryo-EM as the "Method of the Year" in 2015. In the 1960s, transmission electron
Cryo-electron_microscopy
Biological analysis approach
cells in the tissue. The number of Spatial Omics methods published still lags behind the number of methods published for Single-Cell multiomics, but the
Multiomics
Artificial intelligence program by DeepMind
numerous computational methods to predict the 3D structures of proteins from their amino acid sequences, accuracy of such methods in best possible scenario
AlphaFold
Fluorescence microscopy technique
1155/2012/206238. PMC 3335623. PMID 22567307. Editorial: "Method of the Year 2014". Nature Methods. 12 (1): 1. 30 December 2014. doi:10.1038/nmeth.3251. PMID 25699311
Light sheet fluorescence microscopy
Light_sheet_fluorescence_microscopy
Open-source image-processing software
lineages in larval Drosophila brains. Fiji was prominently featured in Nature Methods review supplement on visualization. The lattice fringe spacing of CdSe
Fiji_(software)
Series of techniques in optical microscopy
resolvable in time. These methods include super-resolution optical fluctuation imaging (SOFI) and all single-molecule localization methods (SMLM), such as SPDM
Super-resolution_microscopy
Subfield
imaging methods include multiple techniques combining spatial information with omics data. They include spatial transcriptomics (Nature Method of the Year
Spatial_biology
Study of biochemical processes in an individual cell
proteomics: antibody-based methods, fluorescent protein-based methods, and mass spectroscopy-based methods. The antibody based methods use designed antibodies
Single-cell_analysis
Study of RNA transcripts
arrays, and later reverse transcriptase quantitative PCR (RT-qPCR) methods, but these methods are laborious and can only capture a tiny subsection of a transcriptome
Transcriptomics_technologies
Biomolecule consisting of chains of amino acid residues
under a light microscope, other methods have to be employed to determine their structure. Common experimental methods include X-ray crystallography and
Protein
Subset of artificial intelligence
uninformed (unsupervised) method will easily be outperformed by other supervised methods, while in a typical KDD task, supervised methods cannot be used due
Machine_learning
Interplay between observation, experiment, and theory in science
including Nature and Science, have a policy that researchers must archive their data and methods so that other researchers can test the data and methods and
Scientific_method
Molecular biology technique
profiling of open chromatin, DNA-binding proteins and nucleosome position". Nature Methods. 10 (12): 1213–8. Bibcode:2013NatCB..10.1213B. doi:10.1038/nmeth.2688
ATAC-seq
Methodology for biomedical research
S.; Zhuang, X. (2022-02-10). "High-content CRISPR screening". Nature Reviews Methods Primers. 2 (1) 9. doi:10.1038/s43586-022-00098-7. ISSN 2662-8449
Optical_pooled_screening
Type of genetic engineering
nucleases (TALENs) and engineered meganucleases—were selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science
Genome_editing
Scientific method
concentrations. Light field microscopy methods extend functional readout of neural activity capabilities in 3D volumes. Methods such as fiber photometry, miniscopes
Calcium_imaging
Large-scale study of proteins
common in molecular biology, other methods have been developed as well, that do not rely on an antibody. These methods offer various advantages, for instance
Proteomics
Class of transport proteins
2006). "Channelrhodopsin-2 and optical control of excitable cells". Nature Methods. 3 (10): 785–792. doi:10.1038/nmeth936. PMID 16990810. S2CID 15096826
Channelrhodopsin
Immunology Nature India Nature Italy Nature Machine Intelligence Nature Materials Nature Medicine Nature Metabolism Nature Methods Nature Microbiology Nature Nanotechnology
List of Nature Research journals
List_of_Nature_Research_journals
Chinese-American computational biologist
and translocations — from paired-end sequencing data, published in Nature Methods in 2009. The tool was used in large-scale cancer genome sequencing projects
Ken Chen (computational biologist)
Ken_Chen_(computational_biologist)
DNA sequencing
generation sequencing, also known as next-generation sequencing methods. These methods emerged in 2008, characterized by technologies such as nanopore
Third-generation_sequencing
Fluorescence microscopy imaging method
optical super-resolution microscopy methods, and were featured as Methods of the Year for 2008 by the Nature Methods journal. The development of PALM as
Photoactivated localization microscopy
Photoactivated_localization_microscopy
Calcium imaging technique
of circuit dynamics at multiple sites across the mammalian brain". Nature Methods. 13 (4): 325–328. doi:10.1038/nmeth.3770. ISSN 1548-7105. PMC 5717315
Fiber_photometry
Protein that exhibits bright green fluorescence when exposed to ultraviolet light
Tsien RY (Dec 2005). "A guide to choosing fluorescent proteins" (PDF). Nature Methods. 2 (12): 905–9. doi:10.1038/nmeth819. PMID 16299475. S2CID 10024284
Green_fluorescent_protein
Lineage of cells that evades senescence and continues dividing
"Cell-line authentication demystified". Technology Feature. Nature Methods (Paper "Nature Reprint Collection, Technology Features" (Nov 2014)). 11 (5):
Immortalised_cell_line
Chemically-induced skin irritation following exposure to light
(July 2017). "Assessing phototoxicity in live fluorescence imaging". Nature Methods. 14 (7): 657–661. doi:10.1038/nmeth.4344. hdl:21.11116/0000-0002-8B80-0
Phototoxicity
Microbial protein found in Streptococcus pyogenes M1 GAS
(October 2013). "Cas9 as a versatile tool for engineering biology". Nature Methods. 10 (10): 957–963. doi:10.1038/nmeth.2649. PMC 4051438. PMID 24076990
Cas9
Antibody fragment
(June 2012). "A simple, versatile method for GFP-based super-resolution microscopy via nanobodies". Nature Methods. 9 (6): 582–584. doi:10.1038/nmeth
Single-domain_antibody
Genomic analysis technique
Silvio (July 2017). "Comparison of computational methods for Hi-C data analysis". Nature Methods. 14 (7): 679–685. doi:10.1038/nmeth.4325. ISSN 1548-7105
Hi-C (genomic analysis technique)
Hi-C_(genomic_analysis_technique)
Complete set of molecular interactions in a biological cell
using computational methods (see section above). There have been several efforts to map eukaryotic interactomes through HTP methods. While no biological
Interactome
Taiwanese-American biochemist and bioengineer
Vogt, Nina (January 2020). "RAMPing up voltage indicator imaging". Nature Methods. 17 (1): 25. doi:10.1038/s41592-019-0720-4. PMID 31907465. S2CID 209897141
Michael_Z._Lin
Sequencing of all the exons of a genome
Anne M. Bowcock; Michael Lovett (2005). "Direct Genomic Selection". Nature Methods. 1 (2): 63–69. doi:10.1038/nmeth0105-63. PMID 16152676. S2CID 667227
Exome_sequencing
Field of study
"epiGBS: reference-free reduced representation bisulfite sequencing". Nature Methods. 13 (4): 322–324. doi:10.1038/nmeth.3763. PMID 26855363. S2CID 10457615
Epigenomics
Type of base-pair DNA sequence
Church GM (2013). "Cas9 as a versatile tool for engineering biology". Nature Methods. 10 (10): 957–963. doi:10.1038/nmeth.2649. PMC 4051438. PMID 24076990
Protospacer_adjacent_motif
Group of methods in synthetic biology
long-overlap-based assembly methods developed in recent years. One of the most commonly used methods, the Gibson assembly method, was developed in 2009, and
Artificial_gene_synthesis
Analysis technique of genes
correction methods developed for bulk sequencing data were observed to perform poorly. Consequently, researchers developed statistical methods to correct
Single-cell_transcriptomics
Type of CRISPR tool
"RNA-guided gene activation by CRISPR-Cas9-based transcription factors". Nature Methods. 10 (10): 973–6. doi:10.1038/nmeth.2600. PMC 3911785. PMID 23892895
CRISPR_activation
Method in molecular biology
or 3C-based methods) are a set of molecular biology methods used to analyze the spatial organization of chromatin in a cell. These methods quantify the
Chromosome conformation capture
Chromosome_conformation_capture
American computer scientist and software engineer
lawsuit. Academic researchers raised criticisms of the Nature paper's results and disclosure of methods. In 2023, Professors Chung-Kuan Cheng and Andrew Kahng
Jeff_Dean
Utilizing polymers to examine small biological samples
microscopy with conventional antibodies and fluorescent proteins". Nature Methods. 13 (6): 485–8. doi:10.1038/nmeth.3833. PMC 4929147. PMID 27064647.
Expansion_microscopy
Study of genes found in the environment
biology". Nature Methods. 5 (1): 16–8. doi:10.1038/nmeth1156. PMID 18165802. S2CID 1465786. "Metagenomics versus Moore's law". Nature Methods. 6 (9): 623
Metagenomics
American neuroscientist (born 1979)
2014). "Independent optical excitation of distinct neural populations". Nature Methods. 11 (3): 338–346. Bibcode:2014NatCB..11..338K. doi:10.1038/nmeth.2836
Edward_Boyden
100 different single cell sequencing (omics) methods have been published. The large majority of methods are paired with short-read sequencing technologies
List of single cell omics methods
List_of_single_cell_omics_methods
American chemist and academic
Allison Doerr is the chief editor of the academic journal Nature Methods and an American chemist. She began working there in 2005 and was elevated to chief
Allison_Doerr
Ultrasound technique
Tanter M (July 2011). "Functional ultrasound imaging of the brain". Nature Methods. 8 (8): 662–664. doi:10.1038/nmeth.1641. PMID 21725300. Tanter M, Fink
Functional_ultrasound_imaging
Study of general and fundamental questions
that promote different principles, theories, or methods. Philosophers use a great variety of methods to arrive at philosophical knowledge. They include
Philosophy
Romanian-American scientist
doi:10.1016/j.stem.2016.02.011. PMID 26942851. "Method of the Year 2017: Organoids". Nature Methods. 15: 1. 3 January 2018. doi:10.1038/nmeth.4575. Paşca
Sergiu_P._Pașca
Neuroimaging technique to differentiate neurons
W.; Sanes, J. R. (2013). "Improved tools for the Brainbow toolbox". Nature Methods. 10 (6): 540–547. doi:10.1038/nmeth.2450. PMC 3713494. PMID 23817127
Brainbow
1739–40 book by David Hume
A Treatise of Human Nature: Being an Attempt to Introduce the Experimental Method of Reasoning into Moral Subjects (1739–40) is a book by Scottish philosopher
A_Treatise_of_Human_Nature
DNA / RNA sequencing technique
Watson M (April 2015). "Successful test launch for nanopore sequencing". Nature Methods. 12 (4): 303–4. doi:10.1038/nmeth.3327. PMID 25825834. S2CID 5604121
Nanopore_sequencing
Type of mass spectrometry
Mass Spectrometry-Based Proteomics: An Overview". Quantitative Methods in Proteomics. Methods in Molecular Biology. Vol. 893. pp. 85–100. doi:10.1007/978-1-61779-885-6_7
Tandem_mass_spectrometry
American chemist (born 1959)
within". Nature Methods. 7 (10): 780–781. doi:10.1038/nmeth1010-780a. PMID 20936771. S2CID 31249789. "Nanobiotechnology: Tiny cell transistor". Nature. 466
Charles_M._Lieber
Study of living cells using time-lapse microscopy
(2012-01-01). "Methods for Cell and Particle Tracking". Imaging and Spectroscopic Analysis of Living Cells - Optical and Spectroscopic Techniques. Methods in Enzymology
Live-cell_imaging
Method of species identification using a short section of DNA
DNA barcode for identifying species. Molecular methods are especially useful when traditional methods are not applicable. DNA barcoding has great applicability
DNA_barcoding
Artificial biochemical receptors only responsive to predesigned drugs
BL (August 2008). "Engineering GPCR signaling pathways with RASSLs". Nature Methods. 5 (8): 673–8. doi:10.1038/nmeth.1232. PMC 2703467. PMID 18668035. Armbruster
Receptor activated solely by a synthetic ligand
Receptor_activated_solely_by_a_synthetic_ligand
Nano-scale semiconductor particles
reduced-size quantum dots for imaging receptors on living cells". Nature Methods. 5 (5): 397–399. doi:10.1038/nmeth.1206. PMC 2637151. PMID 18425138
Quantum_dot
Genetically encoded calcium indicator
activity in worms, flies and mice with improved GCaMP calcium indicators". Nature Methods. 6 (12): 875–81. doi:10.1038/nmeth.1398. PMC 2858873. PMID 19898485
GCaMP
Type of unintended effects of genetic modification techniques
Currently there are plenty of biased and unbiased methods for such a screen and only two in vitro methods. All of these are listed below: In case of normal
Off-target_genome_editing
Concept in inferential statistics
2013). "Points of significance: Significance, P values and t-tests". Nature Methods. 10 (11): 1041–1042. doi:10.1038/nmeth.2698. PMID 24344377. Sham, Pak
Statistical_significance
Approach to finding numerical solutions of ordinary differential equations
This makes the Euler method less accurate than higher-order techniques such as Runge–Kutta methods and linear multistep methods, for which the local truncation
Euler_method
Repository of experimental tandem mass spectrometry data
molecular standards database: a broad chemical and biological resource". Nature Methods. 17 (10): 953–954. doi:10.1038/s41592-020-0942-5. ISSN 1548-7105. PMC 8802982
METLIN
Mathematical program specifications
systems, and type theory. Formal methods can be applied at various points through the development process. Formal methods may be used to give a formal description
Formal_methods
Process of determining the nucleic acid sequence
using laborious methods based on two-dimensional chromatography. Following the development of fluorescence-based sequencing methods with a DNA sequencer
DNA_sequencing
American chemist
evolution of APEX2 for electron microscopy and proximity labeling". Nature Methods. 12 (1): 51–4. doi:10.1038/nmeth.3179. PMC 4296904. PMID 25419960. Rhee
Alice_Y._Ting
Patented molecular cloning method
"Enzymatic assembly of DNA molecules up to several hundred kilobases". Nature Methods. 6 (5): 343–345. doi:10.1038/nmeth.1318. PMID 19363495. S2CID 1351008
Gibson_assembly
DNA sequencing method
exploration and discovery, the editors of Nature Methods named long-read sequencing technology its method of the year for 2022. CCS can be useful to
Circular_consensus_sequencing
by multiple-point constraints. Similar to penalty methods, mortar methods are explicit in their nature, i.e. they require the contacting surfaces to be
Mortar_methods
Genus of fishes
as a genetically tractable vertebrate brain model" (PDF). Nature Methods. 15 (11). Nature Publishing Group US New York: 977–983. doi:10.1038/s41592-018-0144-6
Danionella
Computational analysis of large, complex sets of biological data
) is an interdisciplinary field of science that develops computational methods and software tools for understanding biological data, especially when the
Bioinformatics
Kind of single molecule imaging
Several data analysis methods have been developed to analyze the data, such as thresholding methods, Hidden Markov Model (HMM) methods, and transition point
Single-molecule_FRET
Molecular biology techniques
interaction networks using methods of graph theory or statistical methods. The goal of these studies is to understand the nature of interactions in the context
Methods to investigate protein–protein interactions
Methods_to_investigate_protein–protein_interactions
Academic journal
Nature Protocols, published by the Nature Publishing Group, is an on-line scientific journal publishing methods in a recipe-style format. The journal
Nature_Protocols
Single cell RNA sequencing method
CROP-seq (CRISPR droplet sequencing) method as a preprint on bioRxiv, which was subsequently published in Nature Methods in 2017. CROP-seq introduced a key
Perturb-seq
Technique used for light microscopy
LD (March 2015). "A general method to improve fluorophores for live-cell and single-molecule microscopy". Nature Methods. 12 (3): 244–250. doi:10.1038/nmeth
Immunofluorescence
Research tool in genomics
(February 2012). "A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens". Nature Methods. 9 (4): 363–6. doi:10.1038/nmeth
Genome-wide CRISPR-Cas9 knockout screens
Genome-wide_CRISPR-Cas9_knockout_screens
American cardiothoracic surgeon
Tissue-Engineered Blood Vessels for Adult Arterial Revascularization". Nature Methods. 12: 361–365. doi:10.1038/nm1364. PMC 1513140. Jia, Fangjun (2010).
Robert_C._Robbins
Laboratory technique
(February 2018). "Biotinylation by antibody recognition - A method for proximity labeling". Nature Methods. 15 (2): 127–133. doi:10.1038/nmeth.4533. ISSN 1548-7091
Proximity_labeling
expression of data from DNA sequencing methods, like RNA-Seq, SAGE or ChIP-Seq data. edgeR employs statistical methods supported on negative binomial distribution
List of RNA-Seq bioinformatics tools
List_of_RNA-Seq_bioinformatics_tools
Biologist and microscopist
2017 ERC Starting Grant - 3DCellPhase- 2021 Profiled in "Author File," Nature Methods 2021 Chan Zuckerberg Initiative Visual Proteomics Imaging Grant 2023
Julia_Mahamid
Techniques used by historians
of the nature, and the possibility, of a sound historical method is raised within the sub-field of epistemology. The study of historical method and of
Historical_method
different methods used to align reads on reference genome depending on how many mismatches and indels are being allowed. Roughly speaking, the methods can be
Read_(biology)
Material world and its phenomena
method in the last several centuries, nature became the passive reality, organized and moved by divine laws. With the Industrial Revolution, nature increasingly
Nature
Study of biological and neural mechanisma in behaviour
properties to ChR2. Optical techniques – Optical methods for recording neuronal activity rely on methods that modify the optical properties of neurons in
Behavioral_neuroscience
Genetics, Nature Geoscience, Nature Immunology, Nature Materials, Nature Medicine, Nature Methods, Nature Nanotechnology, Nature Neuroscience, Nature Photonics
List of cities by scientific output
List_of_cities_by_scientific_output
(November 2018). "A call for public archives for biological image data". Nature Methods. 15 (11): 849–854. doi:10.1038/s41592-018-0195-8. PMC 6884425. PMID 30377375
List_of_biological_databases
Protein which acts as a fluorophore
"mScarlet: a bright monomeric red fluorescent protein for cellular imaging". Nature Methods. 14 (1): 53–56. doi:10.1038/nmeth.4074. ISSN 1548-7105. PMID 27869816
Red_fluorescent_protein
New Zealand biophysicist (1969–2026)
Biophysics Society in 2012. Marx, Vivien (28 August 2014). "Richard Neutze". Nature Methods. 11 (9): 877. doi:10.1038/nmeth.3074. ISSN 1548-7091. PMID 25317451
Richard_Neutze
Comprehensive map of neural connections in the brain
histological dissection and staining, by degeneration methods, and by axonal tracing. Axonal tracing methods form the primary basis for the systematic charting
Connectome
Method used in molecular biology
Jernej; Zavolan, Mihaela (2021-03-04). "CLIP and complementary methods". Nature Reviews Methods Primers. 1 (1) 20: 1–23. doi:10.1038/s43586-021-00018-1. ISSN 2662-8449
Cross-linking immunoprecipitation
Cross-linking_immunoprecipitation
Inflammatory disease involving a buildup of lesions in the walls of arteries
they may use gene-transfer methods to pass the ability to synthesize the Apo-A1 Milano HDLipoprotein.[citation needed] Methods to increase HDL particle
Atherosclerosis
Huson (2015). "Fast and sensitive protein alignment using DIAMOND". Nature Methods. 12 (1): 59–60. doi:10.1038/nmeth.3176. PMID 25402007. S2CID 5346781
List of sequence alignment software
List_of_sequence_alignment_software
Study of fundamental reality
theories. Due to the abstract nature of its topic, metaphysics has received criticisms questioning the reliability of its methods and the meaningfulness of
Metaphysics
NATURE METHODS
NATURE METHODS
Female
French
French form of Latin Laura, LAURE means "laurel."
Girl/Female
Indian
Sacrifice
Girl/Female
Muslim
Guardian
Male
Turkish
Turkish form of Mongolian Baatar, BATUR means "warrior."
Female
English
English color name AZURE means "sky blue."
Girl/Female
Muslim
Sacrifice
Girl/Female
Hindu, Indian, Kannada, Marathi, Tamil, Telugu
Feature; Future
Girl/Female
Arabic, Muslim
Nature; Natural Disposition
Female
Italian
Italian form of Latin Natalia, NATALE means "birthday," or in Church Latin "Christmas day."
Girl/Female
Muslim
Nature, Natural disposition
Boy/Male
Indian, Punjabi, Sikh
Eyes
Girl/Female
Indian, Tamil
An Expert in Dances
Boy/Male
African, Hindu, Indian
Of the Natine Tribe
Girl/Female
French
Born at Christmas.
Male
Swedish
Danish and Swedish form of Scandinavian Tore, TURE means "thunder."
Boy/Male
Indian, Sanskrit
Clever' Skilful; Beautiful; Charming
Male
Swedish
Swedish name derived from Old Norse stúra, STURE means "obstinate."
Boy/Male
British, English
A Planet
Girl/Female
Indian
Guardian
Boy/Male
Sikh
Warner, Eyes
NATURE METHODS
NATURE METHODS
Boy/Male
Indian
Prem Swarup
Girl/Female
Tamil
Kalpitha | கலà¯à®ªà®¿à®¤à®¾
Imagined, Creative
Girl/Female
Muslim/Islamic
Beautiful girl
Surname or Lastname
English
English : variant spelling of Fillmore.
Male
Swedish
Old Swedish form of Scandinavian Birger, BYRGHIR means "rescuer, saver."
Surname or Lastname
English
English : habitational name from any of the many places in southern England (including nine in Devon) named Buckland, from Old English bÅc ‘book’ + land ‘land’, i.e. land held by right of a written charter, as opposed to folcland, land held by right of custom.
Boy/Male
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Tamil
God of Victory
Surname or Lastname
English
English : habitational name from places in Lancashire and Gloucestershire called Cowhill, from Old English cū ‘cow’ + hyll ‘hill’.possibly also an Americanized form of Polish, Jewish, and Sorbian Kowal.
Girl/Female
Gujarati, Indian
Its One Kind of Rice Type
Surname or Lastname
English
English : variant of or patronymic from Pipe.Greek (PipÄ“s) : from a pet form, Pipis, of the personal name SpyridÅn (see Spiro), borne by a bishop and saint venerated in the Eastern Church. He is the patron saint of Corfu.
NATURE METHODS
NATURE METHODS
NATURE METHODS
NATURE METHODS
NATURE METHODS
imp. & p. p.
of Mature
n.
Physical constitution or existence; the vital powers; the natural life.
a.
Found in nature uncombined with other elements; as, native silver.
a.
Good-natured; kind.
a.
Connected by nature; united in nature; inborn; inherent; natural.
superl.
Of or pertaining to a condition of full development; as, a man of mature years.
a.
Conformed to the order, laws, or actual facts, of nature; consonant to the methods of nature; according to the stated course of things, or in accordance with the laws which govern events, feelings, etc.; not exceptional or violent; legitimate; normal; regular; as, the natural consequence of crime; a natural death.
n.
Conformity to that which is natural, as distinguished from that which is artifical, or forced, or remote from actual experience.
v. t.
To endow with a nature or qualities; to refer to nature.
a.
Resembling the object imitated; true to nature; according to the life; -- said of anything copied or imitated; as, a portrait is natural.
n.
The contrary of nature; that which is unnatural.
v. t.
To endow with natural qualities.
n.
Natural affection or reverence.
a.
Fixed or determined by nature; pertaining to the constitution of a thing; belonging to native character; according to nature; essential; characteristic; not artifical, foreign, assumed, put on, or acquired; as, the natural growth of animals or plants; the natural motion of a gravitating body; natural strength or disposition; the natural heat of the body; natural color.
superl.
Characteristic of the species; belonging to one's nature; natural; native.
a.
Found in nature; not artificial; as native sodium chloride.
a.
Dictated by, or indicating, ill nature; spiteful.
a.
Having (such) a nature, temper, or disposition; disposed; -- used in composition; as, good-natured, ill-natured, etc.
v. t.
To change the nature of; to invest with a different or contrary nature.
v. i.
To advance toward maturity; to become ripe; as, wine matures by age; the judgment matures by age and experience.