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Vesicles released from the outer membranes of Gram-negative bacteria
Outer membrane vesicles (OMVs) are vesicles released from the outer membranes of Gram-negative bacteria. While Gram-positive bacteria release vesicles
Outer_membrane_vesicle
cells, membrane vesicle trafficking is mediated through bacterial outer membrane bounded nano-sized vesicles, called outer membrane vesicles (OMVs).
Membrane_vesicle_trafficking
Any small, fluid-filled, spherical organelle enclosed by a membrane
of the plasma membrane, and intracellular vesicles can fuse with the plasma membrane to release their contents outside the cell. Vesicles can also fuse
Vesicle (biology and chemistry)
Vesicle_(biology_and_chemistry)
Biological process of breaking down food
method for release of material: the formation of outer membrane vesicles. Portions of the outer membrane pinch off, forming spherical structures made of
Digestion
Biological membrane structure
the revelation that nanovesicles, popularly known as bacterial outer membrane vesicles, released by gram-negative microbes, translocate bacterial signal
Lipid_bilayer
Membranes in the cytoplasm of a eukaryotic cell
include: the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, endosomes, and cell membrane among others. The system
Endomembrane_system
Active transport and bulk transport in which a cell transports molecules out of the cell
finding in exocytosis. The periplasm is pinched off as bacterial outer membrane vesicles (OMVs) for translocating microbial biochemical signals into eukaryotic
Exocytosis
Controlled release of substances by cells or tissues
plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structures embedded in the cell membrane, where secretory vesicles transiently
Secretion
Preparation for acquired immunity to disease
approach is used in the Haemophilus influenzae type B vaccine. Outer membrane vesicles (OMVs) are naturally immunogenic and can be manipulated to produce
Vaccine
Biological membrane that separates the interior of a cell from its outside environment
surface of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve
Cell_membrane
Plasma membrane found in gram-negative bacteria
which may be fatal. The bacterial outer membrane is physiologically shed as the bounding membrane of outer membrane vesicles in cultures, as well as in animal
Bacterial_outer_membrane
Species of bacterium
extracellular vesicles(EVs), also referred to as outer membrane vesicles (OMVs). A 2023 study characterized DNA associated with purified extracellular vesicles from
Parabacteroides_goldsteinii
Species of bacterium
have unique outer membrane vesicles. L. pneumophila uses these outer membrane vesicles as a mode of infection. The outer membrane vesicles of the bacteria
Legionella_pneumophila
Species of bacteria
bacterial outer membrane, which gives protection against the gastric acidity. The sheath is also the origin of the outer membrane vesicles that protect
Helicobacter_pylori
in the secretome section. Bacterial outer membrane vesicles Exocytosis Host–pathogen interaction Membrane vesicle trafficking Secretion Secretome Secretomics
Secretory_protein
Nuclear membrane surrounding the nucleus in eukaryotic cells
consists of two lipid bilayer membranes: an inner nuclear membrane and an outer nuclear membrane. The space between the membranes is called the perinuclear
Nuclear_envelope
Toxin from bacteria that destroys or disrupts cells
pathogens may secrete outer membrane vesicles containing lipopolysaccharide endotoxin and some virulence proteins in the bounding membrane along with some other
Exotoxin
Class of molecules found in the outer membrane of Gram-negative bacteria
the normal physiological activity of membrane vesicle trafficking in the form of bacterial outer membrane vesicles (OMVs), which may also contain other
Lipopolysaccharide
Bulge in the plasma membrane of a cell
In cell biology, a bleb (or snout) is a bulge of the plasma membrane of a cell, characterized by a spherical, "blister-like", bulky morphology. It is characterized
Bleb_(cell_biology)
Investigative procedure in microbiology
Avila-Calderón ED, Ruiz-Palma MD, Contreras-Rodríguez A (2021). "Outer Membrane Vesicles of Gram-Negative Bacteria: An Outlook on Biogenesis". Frontiers
Gram_stain
Bacterial diseases
during the 1980s. This vaccine was based on artificially produced outer membrane vesicles of the bacterium. The VA-MENGOC-BC vaccine proved safe and effective
Meningitis_B
Amnion and chorion which surround and protect a developing fetus
fetal membranes surround the developing embryo and form the fetal-maternal interface. The fetal membranes are derived from the trophoblast layer (outer layer
Fetal_membranes
Type of molecules produced by a pathogen that might cause potential harmful effects
virulence factors at host–pathogen interface, via membrane vesicle trafficking as bacterial outer membrane vesicles for invasion, nutrition and other cell-cell
Virulence_factor
Bile acid
characterization and control of MenB-vaccine "Folkehelsa": an outer membrane vesicle vaccine against group B meningococcal disease". NIPH Annals. 14
Deoxycholic_acid
Protein family
the fusion of vesicles with the target membrane; this notably mediates exocytosis, but can also mediate the fusion of vesicles with membrane-bound compartments
SNARE_protein
Vesicles found outside cells
the same manuscript, such as "shedding vesicles," "membrane fragments," "plasma membrane vesicles," "micro-vesicles/microvesicles," "exosomes," (previously
Extracellular_vesicle
Species of bacterium
across a bilipid membrane in a folded state. M. catarrhalis produces and secretes beta-lactamase containing outer-membrane vesicles that can function
Moraxella_catarrhalis
Enclosing or separating membrane in organisms acting as selective semi-permeable barrier
mitochondrion (inner and outer membranes); nucleus (inner and outer membranes); peroxisome; vacuole; cytoplasmic granules; cell vesicles (phagosome, autophagosome
Biological_membrane
Species of bacterium
mechanism of S. maltophilia infection. S. maltophilia secretes outer membrane vesicles (OMVs), which cause an inflammatory response. OMVs from S. maltophilia
Stenotrophomonas_maltophilia
DNA molecules linked to cancer
replicate and retain the cssDNA. The cssDNA derive from bacteria in an outer membrane vesicle OMV and in vitro cross into human tissue culture cells, demonstrating
Bovine_Meat_and_Milk_Factors
Class of peptides that have antimicrobial activity
may degrade antimicrobial peptides leading to their resistance. Outer membrane vesicles produced by Gram-negative bacteria bind the antimicrobial peptides
Antimicrobial_peptides
Species of bacterium
tolerance and preventing excessive inflammatory response. The outer membrane vesicles (OMVs) not only aid in protecting B. thetaiotaomicron from degradation
Bacteroides_thetaiotaomicron
Meningococcal vaccine in New Zealand
meningococcal disease. Each dose is 0.5 ml and contains: 25 mcg of outer membrane vesicles from the Neisseria meningitidis group B strain NZ98/254. The vaccine
MeNZB
suspected to deploy bacterial outer membrane vesicles to translocate effector proteins and virulence factors via a membrane vesicle trafficking secretory pathway
Bacterial_effector_protein
Basic unit of life forms
organelle-like microcompartments such as gas vesicles, and carboxysomes, and encapsulin nanocompartments. Certain membrane-bound prokaryotic organelles have also
Cell_(biology)
Ability of cell membranes to deform elastically
Deformation of a Spherical Vesicle by Pressure, Phys. Rev. Lett. 59 (1987) 2486-2488. [3] O.-Y. Zhong-Can, Anchor Ring-Vesicle Membranes, Phys. Rev. A 41 (1990)
Elasticity_of_cell_membranes
Component of citrus pulp
the weight of an average orange is made up of the membranes of the juice vesicles. Juice vesicles of the endocarp contain the components that provide
Juice_vesicles
Organelle in eukaryotic cells responsible for respiration
functions. These compartments or regions include the outer membrane, intermembrane space, inner membrane, cristae, and matrix. In addition to supplying cellular
Mitochondria
State of being insusceptible or resistant to a noxious agent or process
there are some newer types of vaccines in use: Outer Membrane Vesicle (OMV) vaccines contain the outer membrane of a bacterium without any of its internal
Immunity_(medicine)
American Microbiologist
; Whiteley, Marvin (2012). "A bilayer-couple model of bacterial outer membrane vesicle biogenesis". mBio. 3 (2): e00297–11. Bibcode:2012mBio....397.11S
Marvin_Whiteley
Cell structure involved in protein transport
an outer lattice of Sec13 and Sec31. The COPII coat is responsible for the formation of vesicles from the endoplasmic reticulum (ER). These vesicles transport
COPII
Cell biology structure
autophagosomes deliver cytoplasmic components to the lysosomes. The outer membrane of an autophagosome fuses with a lysosome to form an autolysosome. The
Autophagosome
Specialized subunit within a cell
CoRR hypothesis Ejectosome Endosymbiotic theory Organelle biogenesis Membrane vesicle trafficking Host–pathogen interaction Vesiculo-vacuolar organelle Kerfeld
Organelle
Innermost part of the vertebrate ear
spaces between the outer hair cells. Hardesty's membrane is the layer of the tectoria closest to the reticular lamina and overlying the outer hair cell region
Inner_ear
Protein family
Vitelline membrane outer layer protein I (VMO-I) is a protein domain found on the outside of an egg, in the vitelline membrane. The major role of the vitelline
Vitelline membrane outer layer protein I (VMO-I)
Vitelline_membrane_outer_layer_protein_I_(VMO-I)
Sexually transmitted infection
Goodyear-Smith F, Black S (September 2017). "Effectiveness of a group B outer membrane vesicle meningococcal vaccine against gonorrhoea in New Zealand: a retrospective
Gonorrhea
Species of bacterium
are several N. gonorrhoeae vaccines in development, including an outer membrane vesicle vaccine. This includes the NGoXIM, the native OMV, and Bexsero/4CMenB
Neisseria_gonorrhoeae
Cell organelle that processes proteins
Integral membrane proteins that stay embedded in the membrane as vesicles exit and bind to new membranes. Rab proteins are key in targeting the membrane; SNAP
Endoplasmic_reticulum
membrane curvature and vesicles with high membrane curvature can promote membrane fusion faster than vesicles with lower membrane curvature such as GUVs
Unilamellar_liposome
have been vaccinated against Pasteurella anatis using bacterial outer membrane vesicles purified by hydrostatic filtration dialysis. Several such vaccines
Animal_vaccination
Topics referred to by the same term
Catholic Church Omotic languages (ISO 639-5 language code) Outer membrane vesicles, lipid vesicles released by Gram-negative bacteria OpenMediaVault, a free
OMV_(disambiguation)
Protein-coding gene in the species Homo sapiens
calcium-stimulated dense core vesicle (DCV) exocytosis in a neuroendocrine cell line BON cells. DCV membrane proteins are lost to the plasma membrane during exocytosis
RAB11FIP5
Protein-coding gene in the species Homo sapiens
Synaptic vesicle membrane protein VAT-1 homolog is a protein that in humans is encoded by the VAT1 gene. Synaptic vesicles are responsible for regulating
VAT1
Membrane enclosed compartments in chloroplasts and cyanobacteria
endoplasmic reticulum and inner membrane of the plastid envelope and transported from the inner membrane to the thylakoids via vesicles. The thylakoid lumen is
Thylakoid
RNA family
in an increase in outer membrane vesicles secreted. From these studies it has been suggested that VrrA acts to relieve outer membrane stress by limiting
Vibrio_regulatory_RNA_of_OmpA
Area within computer science
behind the notion of a membrane is a three-dimensional vesicle from biology. However the concept itself is more general, and a membrane is seen as a separator
Membrane_computing
Biological process that prevents polyspermy
secretory vesicles located within the egg's cortex (the region directly below the plasma membrane), are fused with the egg's plasma membrane. This releases
Cortical_reaction
Development and formation of the human embryo
the fetal part of the placenta will form from the outer trophoblast layer. The embryo plus its membranes is called the conceptus, and by this stage the conceptus
Human_embryonic_development
Species of bacterium
complex series of surface proteins, lipopolysaccharide chains, and outer membrane vesicles to help survive the volatile intestinal micro-environment. B. fragilis
Bacteroides_fragilis
mechanism of membrane fusion: Kinetics of calcium ion induced fusion of phosphatidylserine vesicles followed by a new assay for mixing of aqueous vesicle contents"
Lipid_bilayer_fusion
Genus of Protozoa
into the vesicles. This builds an osmotic gradient across the vesicle membrane, leading to influx of water from the cytosol into the vesicles by osmosis
Amoeba_(genus)
Species of bacterium
Juan A.; Schinnerling, Katina (2025-04-11). "Segatella copri Outer-Membrane Vesicles Are Internalized by Human Macrophages and Promote a Pro-Inflammatory
Prevotella_copri
nanoparticles Pigments, paints and sun creams Exosomes, microvesicles, outer membrane vesicles, and other small biological particles Pharmaceutical particles
NanoSight
Lipid globule proposed as a precursor of living cells
resulting in the formation of membrane structures such as bilayers, vesicles, and micelles. In modern cells, vesicles are involved in metabolism, transport
Protocell
Protein found in humans
small vesicles. Alpha-synuclein has been shown to bend membranes of negatively charged phospholipid vesicles and form tubules from large lipid vesicles. Using
Alpha-synuclein
Organ of hearing and balance
the ear canal, and the outer layer of the eardrum the tympanic membrane. Since the outer ear is the only visible portion of the ear, the word "ear" often
Ear
Antibiotic-resistant bacteria
plasmid and insertion-sequence contexts among Enterobacterales. Outer membrane vesicles (OMVs), that can transfer DNA between bacterial cells, are produced
Carbapenem-resistant enterobacteriaceae
Carbapenem-resistant_enterobacteriaceae
Species of bacterium
bacteria in both in vivo and in vitro experiments. P. gingivalis outer membrane vesicles were found to be necessary for the invasion of epithelial cells
Porphyromonas_gingivalis
Plant organelle that conducts photosynthesis
interpreted as meaning the outer chloroplast membrane is the product of the host's cell membrane infolding to form a vesicle to surround the ancestral
Chloroplast
Specialized anatomy and physiology of bacteria
dyes methylene blue or toluidine blue. Gas vacuoles are membrane-bound, spindle-shaped vesicles, found in some planktonic bacteria and Cyanobacteria, that
Bacterial_cell_structure
American physician-scientist
(2005). "Protective antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed genome-derived neisserial antigen 1870"
Dan_M._Granoff
active forms: a free, soluble form and another form associated with outer membrane vesicles (OMVs) released by the bacteria. The OMV-associated form is more
Enterohemolysin
Protein complex that coats membrane-bound transport vesicles
The coatomer is a protein complex that coats membrane-bound transport vesicles. Two types of coatomers are known: COPI (retrograde transport from trans-Golgi
Coatomer
Evolutionary theory
network like eukaryotes, but they could produce extracellular vesicles from their outer membrane. After the early prokaryote was consumed by a proto-eukaryote
Symbiogenesis
Species of bacterium
mortality. Vaccines for chickens have been developed using bacterial outer membrane vesicles purified by hydrostatic filtration dialysis. Several of these have
Gallibacterium_anatis
Composite structure formed by phospholipids
A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility
Liposome
Formation of the eye during embryonic development
develop as a pair of optic vesicles on each side of the forebrain at the end of the fourth week of pregnancy. Optic vesicles are outgrowings of the brain
Eye_development
and lifetimes of several hours will become feasible. Unlike a vesicle or a cell membrane in which the lipid bilayer is rolled into an enclosed shell, a
Model_lipid_bilayer
Species of bacterium
peptides, V. cholera uses its outer membrane vesicles (OMVs). Upon entry, the bacteria sheds its OMVs, containing all the membrane modifications that make it
Vibrio_cholerae
Type of programmed cell death
injury associated with chronic inflammation will occur. Moreover, Outer Membrane Vesicles (OMVs) released from some Gram-negative bacteria are sufficient
Pyroptosis
System of communication
Molecular cellular cognition Crosstalk (biology) Bacterial outer membrane vesicles Membrane vesicle trafficking Host–pathogen interaction Retinoic acid JAK-STAT
Cell_signaling
British vaccinologist
modules for membrane antigens (GMMA). Vaccine 2014; 32: 2688–95. 2018 Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate
Calman_MacLennan
Inner part of a cell's cytoplasm
flux through intracellular transport, as vesicles are shuttled between organelles and to/from the plasma membrane. Materials are regularly both degraded
Endoplasm
Membrane proteins that adhere temporarily to membranes with which they are associated
Peripheral membrane proteins, or extrinsic membrane proteins, are membrane proteins that adhere only temporarily to the biological membrane with which
Peripheral_membrane_protein
Genus of archaea
to 400 nm, containing membrane-bound vesicles), and an outer membrane (approximately 10 nm wide, resembling the outer membrane of gram-negative bacteria)
Ignicoccus
Auditory sensory receptor nerve cells
the auditory cortex. The tectorial membrane (TM) overlying the sensory inner hair cells and electrically-motile outer hair cells stimulates IHCs through
Hair_cell
Static membrane potential in biology
membrane potential across synaptic vesicle membranes).[citation needed] In most quantitative treatments of membrane potential, such as the derivation of
Resting_potential
Class of chemical compounds
embedded in the surface of a vesicle which is then transported to the cell membrane. The vesicle merges with the cell membrane so that the glycolipid can
Glycolipid
Ability of lipids to aggregate into a variety of structured phases
crystal Membrane lipids Negative staining Stuart, Marc & Boekema, Egbert. (2007). Two distinct mechanisms of vesicle-to-micelle and micelle-to-vesicle transition
Lipid_polymorphism
Eye structure
below the basement membrane surrounding the lens. As a result, the vertebrate lens grows throughout life. The surrounding lens membrane referred to as the
Lens_(vertebrate_anatomy)
Species of bacteria
by the presences of outer membrane vesicles (OMVs). OMVs are produced via vesiculation, which is the bulging of the outer membrane followed by the constriction
Acinetobacter_baylyi
Cavity in the cochlea of the inner ear
the basilar membrane. It also contains endolymph, which contains high concentrations of K+ for the function of inner hair cells and outer hair cells in
Cochlear_duct
Genus of bacteria
ISBN 978-2-88919-576-3. Grenier, Daniel (2013). "Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and
Lachnoanaerobaculum
Bacterial virulence factor
proposed to rivet gram negative bacterial outer and inner membranes to help release outer membrane vesicles targeted to deliver bacterial secretions to
Type_III_secretion_system
Gut bacteria found in mice
able to see it and analyze it. This procedure revealed multiple outer membrane vesicles which are small sacs that carry various bacterial components. In
Tomasiella_immunophila
Indian academic
His research supported new methods of gene transfer through the outer membrane vesicle of Acinetobacter baylyi. Research by him also helped establish Acinetobacter
Balu_Ananda_Chopade
Electrochemical principle that enables cellular respiration
They would release electrons across the lipid membrane by diffusion to ferricyanide within the vesicles and release protons which produces gradients above
Chemiosmosis
Biomedical engineer
Recombinant Subunit Vaccines Delivered by Probiotic Bacteria-Derived Outer Membrane Vesicles. PLoS ONE 9(11): e112802. University, Carnegie Mellon. "Elizabeth
Elizabeth_Wayne
Vesicle formed around a particle engulfed by a phagocyte via phagocytosis
In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis. Professional phagocytes include macrophages
Phagosome
Biological mechanism for routing proteins
prokaryotes lack membrane-bound organelles as found in eukaryotes, but they may assemble proteins onto various types of inclusions such as gas vesicles and storage
Protein_targeting
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