Searches , social queries for WINGED HELIX-REPAIR-FACTOR-1
Search references for WINGED HELIX-REPAIR-FACTOR-1. Phrases containing WINGED HELIX-REPAIR-FACTOR-1
See searches and references containing WINGED HELIX-REPAIR-FACTOR-1!
Search references for WINGED HELIX-REPAIR-FACTOR-1. Phrases containing WINGED HELIX-REPAIR-FACTOR-1
See searches and references containing WINGED HELIX-REPAIR-FACTOR-1!WINGED HELIX-REPAIR-FACTOR-1
Protein-coding gene in humans
Winged helix repair factor 1 is a protein that in humans is encoded by the WHR1 gene (previously STK19) and is involved in DNA repair, specifically the
Winged_helix_repair_factor_1
Human genetic cluster on chromosome 6
more modules each having a series of genes close to each other: winged helix repair factor 1 (WHR1), complement 4 (C4), steroid 21-hydroxylase (CYP21), and
RCCX
Self-stabilizing region of a protein that binds to specific DNA sequences
about 110 amino acids, the winged helix (WH) domain has four helices and a two-strand beta-sheet. The winged helix-turn-helix (wHTH) domain SCOP 46785 is
DNA-binding_domain
Transcription factor protein
Twist-related protein 1 (TWIST1) also known as class A basic helix–loop–helix protein 38 (bHLHa38) is a basic helix-loop-helix transcription factor that in humans
Twist-related_protein_1
Mammalian protein found in humans
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded
Microphthalmia-associated transcription factor
Microphthalmia-associated_transcription_factor
Protein-coding gene in the species Homo sapiens
consists of a series of modules with genes close to each other: winged helix repair factor 1 (WHR1), complement 4 (C4), steroid 21-hydroxylase (CYP21), and
Tenascin_X
Mammalian protein found in Homo sapiens
proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation
MyoD
Protein complex
factor II H (TFIIH) is a multi-subunit protein complex involved in both the transcription of protein-coding genes and the nucleotide excision repair (NER)
Transcription_factor_II_H
Medical condition
composed of the names of the genes RP (a former name for WHR1 Winged helix repair factor 1), C4, CYP21 and TNX), which is the most complex gene cluster
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency
Protein-coding gene in the species Homo sapiens
myogenesis and muscle regeneration. Myogenic factors are basic helix-loop-helix (bHLH) transcription factors. MYF6 is a gene that encodes a protein involved
MYF6
Protein-coding gene in the species Homo sapiens
ETS genes in humans and 27 in mice. They bind the DNA via their winged-helix-turn-helix DNA binding motif known as the Ets domain that specifically recognizes
ETS1
Human enzyme that hydroxylates steroids
composed of the names of the genes RP (a former name for WHR1 Winged helix repair factor 1), C4, CYP21 and TNX), which is the most complex gene cluster
21-Hydroxylase
Protein that responds to low oxygen
translocator (ARNT). HIF-1 belongs to the PER-ARNT-SIM (PAS) subfamily of the basic helix-loop-helix (bHLH) family of transcription factors. The alpha and beta
Hypoxia-inducible_factor
Protein-coding gene in humans
"Basic helix-loop-helix family, member e41", or BHLHE41, is a gene that encodes a basic helix-loop-helix transcription factor repressor protein in various
BHLHE41
DNA pattern affecting anatomy development
following shows the consensus homeodomain (~60 amino acid chain): Helix 1 Helix 2 Helix 3/4 ______________ __________ _________________
Homeobox
Protein-coding gene in humans
myc-associated factor X) is a gene that in humans encodes the MAX transcription factor. The protein product of MAX contains the basic helix-loop-helix and leucine
MAX_(gene)
Family of transcription factors involved in anatomical development
a winged helix, due to the butterfly-like appearance of the loops in the protein structure of the domain. FOX proteins are a subgroup of the helix-turn-helix
FOX_proteins
Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)
protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress
AP-1_transcription_factor
Protein found in humans
Oligodendrocyte transcription factor (OLIG2) is a basic helix-loop-helix (bHLH) transcription factor encoded by the OLIG2 gene. The protein is of 329 amino
OLIG2
Family of transcription factors
analysis has shown that the E2F family of transcription factors has a fold similar to the winged-helix DNA-binding motif. E2F family members play a major role
E2F
Molecule that carries genetic information
two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning
DNA
Mammalian protein found in humans
muscle-specific basic-helix-loop-helix (bHLH) transcription factor involved in the coordination of skeletal muscle development or myogenesis and repair. Myogenin
Myogenin
Group of proteins
etc. TCF/LEF family (T cell factor/lymphoid enhancer factor family) LEF1 (Lymphoid enhancer-binding factor 1) TCF7 (TCF-1) TCF7L1 (TCF-3) TCF7L2 (TCF-4)
High-mobility_group
Mammalian protein found in Homo sapiens
Liang H, et al. (June 2016). "A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks". Nucleic Acids Research
Proliferating cell nuclear antigen
Proliferating_cell_nuclear_antigen
Protein-coding gene in the species Homo sapiens
Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded
HIF1A
Transcriptional repressor protein
Yang 1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene. YY1 is a ubiquitously distributed transcription factor belonging
YY1
Sequence in a genome
and winged-helix folds and co-assemble into a pentameric ring that encircles DNA. In budding yeast ORC, DNA binding elements in the ATPase and winged-helix
Origin_of_replication
Protein family
early steps in DNA repair. Other earlier proteins may be recruited with a t1/2 of 40 seconds for UV damage and a t1/2 of about 1 second in response to
Heterochromatin_protein_1
Protein-coding gene in the species Homo sapiens
a member of the MYC family of transcription factors and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the
N-Myc
Protein-coding gene in the species Homo sapiens
stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene. The upstream stimulatory factor (USF) gene encodes a transcription factor USF that
USF1
Mammalian protein found in humans
in DNA repair pathways. This includes components of base excision repair (BER) such as OGG1 and MUTYH, nucleotide excision repair (NER) factors like DDB2
P53
Small structural protein motif found mostly in transcriptional proteins
DNA-binding proteins that bind DNA through the 2-fold symmetry of the double helix, instead zinc fingers are linked linearly in tandem to bind nucleic acid
Zinc_finger
Protein-coding gene in the species Homo sapiens
Transcription factor Sp7, also called Osterix (Osx), is a protein that in humans is encoded by the SP7 gene. It is a member of the Sp family of zinc-finger
Sp7_transcription_factor
Protein-coding gene in the species Homo sapiens
chromosome 1 at 17.98 centimorgans and is 169,505 bases long. The NPAS2 protein is a member of the basic helix-loop-helix (bHLH)-PAS transcription factor family
NPAS2
Protein family
activity for neural repair and regeneration. Neurogenin 1 (Ngn1) is a Class-A basic-helix-loop-helix (bHLH) transcription factor that acts as a regulator
Neurogenins
Protein-coding gene in the species Homo sapiens
Heat shock factor protein 1 (HSF 1) is a protein that in humans is encoded by the HSF1 gene. HSF1 is highly conserved in eukaryotes and is the primary
Heat_shock_factor_protein_1
Family of regulator genes
genes all belong to the Myc family of transcription factors, which contain bHLH (basic helix-loop-helix) and LZ (leucine zipper) structural motifs. The bHLH
Myc
Protein-coding gene in the species Homo sapiens
K, Vandekerckhove L, Christ F, Debyser Z (Feb 2006). "Cellular co-factors of HIV-1 integration". Trends in Biochemical Sciences. 31 (2): 98–105. doi:10
HMGA1
Protein-coding gene in the species Homo sapiens
Colmenares SU, Kobayashi R, Hernandez N (Apr 1999). "FBI-1, a factor that binds to the HIV-1 inducer of short transcripts (IST), is a POZ domain protein"
ZBTB7A
Protein-coding gene in the species Homo sapiens
cell growth, differentiation, DNA repair, and thereby aging". Annals of the New York Academy of Sciences. 1100 (1): 299–305. Bibcode:2007NYASA1100..299P
KAT6B
Protein found in humans
"Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair". The Journal of Biological Chemistry. 291
Homeobox_protein_cut-like_1
Group of proteins
involved in regulation of transcription, replication, recombination, and DNA repair. HMGN1 and HMGN2 (initially designated HMG-14 and HMG-17 respectively) were
HMGN
Protein-coding gene in humans
(January 2025). "Pan-Cancer Upregulation of the FOXM1 Transcription Factor". Genes. 16 (1): 56–66. doi:10.3390/genes16010056. PMC 11765198. PMID 39858603
FOXM1
Protein-coding gene
Carbon P (2007). "Transcription factor hStaf/ZNF143 is required for expression of the human TFAM gene". Gene. 401 (1–2): 145–53. doi:10.1016/j.gene.2007
ZNF143
Protein-coding gene in the species Homo sapiens
transcription factor 1". Zhou Q, Wang S, Anderson DJ (Feb 2000). "Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription
OLIG1
Protein-coding gene in the species Homo sapiens
2B RAX SHOX SHOX2 VSX1 VSX2 Bicoid GSC BICD2 OTX 1 2 PITX 1 2 3 (3.3) Fork head / winged helix E2F 1 2 3 4 5 FOX proteins A1 A2 A3 B1 B2 C1 C2 D1 D2 D3
ZNF365
Protein-coding gene in the species Homo sapiens
(PRRs) can activate BLIMP-1, both as a direct target and through downstream activation. BLIMP-1 is a transcription factor that triggers expression of
PRDM1
Protein-coding gene in the species Homo sapiens
ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. GRCh38: Ensembl release 89: ENSG00000164104 – Ensembl
HMGB2
Mammalian protein found in humans
TATA-binding protein-associated factor TAFII250". Molecular and Cellular Biology. 19 (1): 846–54. doi:10.1128/MCB.19.1.846. PMC 83941. PMID 9858607. Shao
Retinoblastoma_protein
Protein-coding gene in the species Homo sapiens
growth family, member 1". Cheung KJ, Mitchell D, Lin P, Li G (July 2001). "The tumor suppressor candidate p33(ING1) mediates repair of UV-damaged DNA".
ING1
TBX1 deficiency CHARGE syndrome (CHD7 deficiency or SEMA3E deficiency) Winged helix/FOXN1 deficiency Chromosome 10p13-p14 deletion Immuno-osseous dysplasias
List of primary immunodeficiencies
List_of_primary_immunodeficiencies
Protein-coding gene in the species Homo sapiens
Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL genes were identified based
SALL4
Protein-coding gene in the species Homo sapiens
ETV6 (i.e. translocation-Ets-leukemia virus) protein is a transcription factor that in humans is encoded by the ETV6 (previously known as TEL) gene. The
ETV6
Protein-coding gene in the species Homo sapiens
transcription factor TBX3 is a protein that in humans is encoded by the TBX3 gene. T-box 3 (TBX3) is a member of the T-box gene family of transcription factors which
TBX3
Human protein and coding gene
transcription factor that is encoded by the DDIT3 gene. It is a member of the CCAAT/enhancer-binding protein (C/EBP) family of DNA-binding transcription factors. The
DNA damage-inducible transcript 3
DNA_damage-inducible_transcript_3
Protein-coding gene in the species Homo sapiens
heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome
Structure specific recognition protein 1
Structure_specific_recognition_protein_1
Nuclear receptor protein found in humans
transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics".
Peroxisome proliferator-activated receptor delta
Peroxisome_proliferator-activated_receptor_delta
Protein found in humans
to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell
Cullin-4A
Protein-coding gene in the species Homo sapiens
Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known
RELA
Protein-coding gene in the species Homo sapiens
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein
BACH1
Protein needed for initiation of transcription in prokaryotes
proteases and DNA-repair enzymes. σ38 (RpoS) – the starvation/stationary phase sigma factor σ54 (RpoN) – the nitrogen-limitation sigma factor There are also
Sigma_factor
Protein-coding gene in the species Homo sapiens
enhancer-binding factor 1 (LEF1) is a protein that in humans is encoded by the LEF1 gene. It is a member of T cell factor/lymphoid enhancer factor (TCF/LEF)
Lymphoid enhancer-binding factor 1
Lymphoid_enhancer-binding_factor_1
Protein-coding gene in the species Homo sapiens
name LIM was derived from the first letter of the transcription factors LIN-11, ISL-1 and MEC-3, from which the domain was originally characterized. No
FHL2
Protein-coding gene in the species Homo sapiens
(2005). "Regulation of LSD1 histone demethylase activity by its associated factors". Mol. Cell. 19 (6): 857–64. doi:10.1016/j.molcel.2005.08.027. PMID 16140033
PHF21A
Protein-coding gene in the species Homo sapiens
in the cellular stress response. The X-box binding protein 1 (XBP1) is a transcription factor containing a bZIP domain. It was first identified by its ability
XBP1
Protein-coding gene in the species Homo sapiens
Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene. The protein encoded by this gene is a member of the E2F family of transcription
E2F1
Proteins activated by the hormone estrogen
transcription factors regulating protein production. The receptor also interacts with transcription factors such as activator protein 1 and Sp-1 to promote
Estrogen_receptor
Mammalian protein found in Homo sapiens
(1–2): 149–56. doi:10.1016/j.bbagrm.2009.11.019. PMC 4533842. PMID 19948257. Pazzaglia S, Pioli C (2019). "Multifaceted Role of PARP-1 in DNA Repair and
HMGB1
Protein-coding gene in the species Homo sapiens
evolved. Tumor protein p63 is a member of the p53 family of transcription factors. p63 -/- mice have several developmental defects which include the lack
TP63
Protein-coding gene in the species Homo sapiens
Krüppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a member of the KLF family of zinc finger transcription factors, which belongs
KLF4
Protein found in humans
DDB1 adaptor protein which interacts with numerous DDB1-CUL4-Associated Factors (DCAFs). This interaction is crucial for the recruitment of substrates
Cullin-4B
Protein-coding gene in humans
transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene
CEBPB
Protein-coding gene in the species Homo sapiens
transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription factor within
T-box_transcription_factor_T
Protein-coding gene in the species Homo sapiens
Y, Willey JC (October 2005). "CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not
CEBPG
Protein-coding gene in humans
Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) and it
RUNX1
Protein-coding gene in the species Homo sapiens
"Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1". The EMBO Journal. 25 (6):
MTA1
Comic book character
Sabretooth's back and leaves him for dead. It takes weeks for his healing factor to repair his spine, during which he sustains himself on sewer water and passing
Sabretooth_(character)
Protein found in humans
endonuclease 1 and HMGA2 in cancer cells has been demonstrated indicating that HMGA2 can be incorporated into the cellular base excision repair (BER) machinery
HMGA2
Protein-coding gene in the species Homo sapiens
condensin to have dynamic properties. The C terminus end of NCAPH assumes a winged-helix conformation, which then associates with either head group of the SMC
NCAPH
Protein-coding gene in the species Homo sapiens
Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription
E2F3
Immune system protein
chromosome 21q22.3 that encodes 545 amino acids. AIRE is a transcription factor expressed in the medulla (inner part) of the thymus. It is part of the mechanism
Autoimmune_regulator
Protein-coding gene in the species Homo sapiens
characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH". EMBO J. 16 (5): 1093–102. doi:10.1093/emboj/16.5.1093. PMC 1169708
GTF2H4
Protein-coding gene in the species Homo sapiens
acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. GRCh38: Ensembl release 89: ENSG00000168556 – Ensembl, May
ING2
Protein-coding gene in the species Homo sapiens
polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene
GTF2H2
Protein-coding gene in the species Homo sapiens
Y box binding protein 1 (YB-1), also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1, is a protein that in humans is
Y_box_binding_protein_1
Protein-coding gene in the species Homo sapiens
T-box transcription factor TBX1 also known as T-box protein 1 and testis-specific T-box protein is a protein that in humans is encoded by the TBX1 gene
TBX1
Protein-coding gene in humans
the ETS (erythroblast transformation-specific) family of transcription factors. Genes in the ETS family regulate embryonic development, cell proliferation
ERG_(gene)
Protein-coding gene in the species Homo sapiens
encoded by the gene ESR1 (EStrogen Receptor 1). The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important
Estrogen_receptor_alpha
Protein-coding gene in the species Homo sapiens
General transcription factor IIH subunit 1 is a protein that in humans is encoded by the GTF2H1 gene. GTF2H1 has been shown to interact with: Cyclin-dependent
GTF2H1
DNA replication in eukaryotic organisms
while a winged helix domain of Orc4 contacts the methyl groups of the invariant Ts in the major groove of the A element via an insertion helix (IH). The
Eukaryotic_DNA_replication
1948, Pauling discovered that many proteins included helical (see alpha helix) shapes. Pauling had deduced this structure from X-ray patterns and from
History_of_molecular_biology
Type of wind turbine
Darrieus wind turbine. The Darrieus rotor comes in various subforms, including helix-shaped, disc-like, and the H-rotor with straight blades. These turbines
Vertical-axis_wind_turbine
Protein-coding gene in humans
shows active sites within the JmjC domains, a dimerization domain, and a winged-helix domain. The crystal structure of RIOX1 folds into a functional tetrameric
RIOX1
Protein-coding gene in humans
bound by PDS5A, PDS5B or NIPBL. The C-terminal domain of RAD21 forms a winged helix that binds two β-sheets in the Smc1 head domain. WAPL releases cohesin
RAD21
Suspension bridge between New Jersey and New York
be replaced, at an expected cost of more than $1 billion paid for by toll revenue. In August 2013, repair crews began an $82 million effort to fix cracks
George_Washington_Bridge
Gene family
function in non-transport-related processes such as translation of RNA and DNA repair. ABC transporters are considered to be an ABC superfamily based on the similarities
ABC_transporter
Protein complex that regulates the separation of sister chromatids during cell division
bound by PDS5A, PDS5B or NIPBL. The C-terminal domain of RAD21 forms a winged helix that binds two β-sheets in the Smc1 head domain. Once RAD21 binds the
Cohesin
Class of enzymes
protein contains a Toprim fold and a DNA-binding core that contains a winged helix domain (WHD), often referred to as a CAP domain, since it was first identified
Type_II_topoisomerase
hypoxia-inducible factor 1, alpha subunit MeSH D12.776.260.103.750.590 – myod protein MeSH D12.776.260.103.750.595 – myogenic regulatory factor 5 MeSH D12.776
List of MeSH codes (D12.776.260)
List_of_MeSH_codes_(D12.776.260)
(similar to Sabretooth), a healing factor, and enhanced physical capabilities. [volume and issue needed] His healing factor allows him to rapidly regenerate
List of Marvel Comics characters: S
List_of_Marvel_Comics_characters:_S
travel, tourism, insurance
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
WINGED HELIX-REPAIR-FACTOR-1
travel, tourism, insurance