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Protein found in humans
invader, the complement system becomes activated. This activation process involves complement component 2 protein attaching to complement component 4 protein
Complement_component_2
Protein involved in the immune system
the human leukocyte antigen (HLA) system, which when paired with complement component 2 (C2) is imperative in generating an immune response. C4 serves a
Complement_component_4
Protein complex
The complement component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together
Complement_component_1q
Protein found in humans
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved
Complement_component_5
Protein-coding gene in humans
with C1q and C1s form the C1 complex, which is the first component of the serum complement system. C1r is an enzyme that activates C1s to its active
Complement_component_1r
Protein found in humans
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system
Complement_component_1s
Protein fragment
cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an
Complement_component_5a
Protein-coding gene in the species Homo sapiens
Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes
Complement_component_4B
Protein found in humans
Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It
Complement_component_6
Medical condition
Complement 2 deficiency is a type of complement deficiency caused by any one of several different alterations in the structure of complement component
Complement_2_deficiency
Protein-coding gene in the species Homo sapiens
component of the alternative pathway of complement activation. It is directly paralogous to complement component 2 (C2) of the classical pathway, occupying
Complement_factor_B
Topics referred to by the same term
2, the axis, one of the cervical vertebrae of the vertebral column Cervical spinal nerve 2 Chlorophyll c2, a form of chlorophyll Complement component
C2
Part of the immune system that enhances the ability of antibodies and phagocytic cells
component of fresh serum. Ehrlich, therefore, named this heat-labile component "complement," because it is something in the blood that "complements"
Complement_system
Autoimmune disease in which the immune system attacks healthy tissue
Complement component 1qA, Complement component 1qB, Complement component 1r, Complement component 1s, Complement component 2, Complement component 3
Lupus
Protein found in humans
Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein–Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein
Complement_receptor_2
Vision loss due to damage to the macula of the eye
location 10q26 Complement factor B/complement component 2 (CFB/CC2) on chromosome 6 at 6p21.3[citation needed] Polymorphisms in genes for complement system proteins:
Macular_degeneration
(2022-07-07). "Insights Into the Pathogenesis of Bullous Pemphigoid: The Role of Complement-Independent Mechanisms". Frontiers in Immunology. 13. Frontiers Media
List_of_autoimmune_diseases
Protein involved in the complement system
Complement component 8 is a protein involved in the complement system. It is part of the membrane attack complex (MAC). A hereditary deficiency of C8 can
C8_complex
Protein complex
complex (complement component 1, C1) is a protein complex involved in the complement system. It is the first component of the classical complement pathway
C1_complex
Protein-coding gene in the species Homo sapiens
Complement component 5a receptor 2 is a protein of the complement system that in humans is encoded by the C5AR2 gene. It is highly expressed in the blood
C5AR2
Medical condition
Complement component 1qA, Complement component 1qB, Complement component 1r, Complement component 1s, Complement component 2, Complement component 3
Childhood-onset systemic lupus erythematosus
Childhood-onset_systemic_lupus_erythematosus
Medical condition
Deficiencies of the terminal complement components increases susceptibility to infections by Neisseria. The cause of complement deficiency is genetics (though
Complement_deficiency
C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue anaphylatoxin that binds to the C3a
C3a_(complement)
Protein-coding gene in the species Homo sapiens
Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene. This gene encodes the acidic form of complement
C4A
Medical condition
proteins in the complement cascade are activated, including complement component 2 (C2), complement component 3 (C3), and complement component 4 (C4). When
Acquired C1 esterase inhibitor deficiency
Acquired_C1_esterase_inhibitor_deficiency
Aspect of the immune system
classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway
Classical_complement_pathway
variable immunodeficiency Compartment syndrome Complement component 2 deficiency Complement component receptor 1 Complete atrioventricular canal Complex
List_of_diseases_(C)
Mammalian protein found in Homo sapiens
The C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a
C5a_receptor
Protein complex
cells, leading to cell lysis and death. The MAC is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. A number of proteins participate
Complement membrane attack complex
Complement_membrane_attack_complex
Protein family
express complement receptors on their surface. All four complement receptors can bind to fragments of complement component 3 or complement component 4 coated
Complement_receptor
Type of cascade reaction of the complement system
alternative pathway is a type of cascade reaction of the complement system and is a component of the innate immune system, a natural defense against infections
Alternative complement pathway
Alternative_complement_pathway
Protein found in humans
of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes". Annals of Human Genetics. 52 (2): 117–122
Complement_receptor_1
Protein domain
or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement components C3
Anaphylatoxin
Complement control proteins are proteins that interact with components of the complement system. The complement system is tightly regulated by a network
Complement_control_protein
Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3". J. Immunol. 144 (7): 2771–80. doi:10.4049/jimmunol
Macrophage-1_antigen
Two tame knots with homeomorphic complements are the same or mirror images
complements are all homeomorphic to the complement of the Whitehead link. His construction is to twist along a disc spanning an unknotted component (as
Gordon–Luecke_theorem
Protein-coding gene in humans
receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system. The receptor
C3a_receptor
Medical condition
Gewurz H (November 1980). "Inherited deficiency of the ninth component of complement in man". J. Immunol. 125 (5): 2252–7. doi:10.4049/jimmunol.125
Terminal complement pathway deficiency
Terminal_complement_pathway_deficiency
Pronunciation guide accompanying logographic writing
A phonetic complement is a phonetic symbol used to disambiguate word characters (logograms) that have multiple readings, in mixed logographic-phonetic
Phonetic_complement
Type of cascade reaction in the complement system
residues on the surface of a pathogen, MASP-1 and MASP-2 are activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b. In addition
Lectin_pathway
Form of musical chord
subject to timbral variation. The notes the performers sing are harmonics 2, 3, 4, 5, 7, and 9 of the implied but absent fundamental—the B flat below
Ninth_chord
Second mode of the melodic minor scale
The Dorian ♭2 scale (pronounced "Dorian flat two"), also known as the Phrygian ♮6 scale (Phrygian sharp six), or the Javanese scale is the second mode
Dorian_flat_2_scale
Protein complex involved in the complement system
C4b-binding protein (C4BP) is a protein complex involved in the complement system where it acts as inhibitor. C4BP has an octopus-like structure with a
C4b-binding_protein
Lack of or compromised immune system
spleen Complement deficiency is where the function of the complement system is deficient In reality, immunodeficiency often affects multiple components, with
Immunodeficiency
Medical condition
Complement 3 deficiency is a genetic condition affecting complement component 3 (C3). People can suffer from either primary or secondary C3 deficiency
Complement_3_deficiency
Aspect of immunity
microorganisms. Alexins, later redefined as "complements" by Paul Ehrlich, were shown to be the soluble components of the innate response that leads to a combination
Humoral_immunity
Protein
purification and measurement of nine components of hemolytic complement in guinea-pig serum". Immunochemistry. 3 (2): 111–35. doi:10.1016/0019-2791(66)90292-8
Complement_factor_I
Pharmaceutical drug
(NMOSD). It is designed to bind to and prevent the activation of complement component 5 (C5). Paroxysmal nocturnal hemoglobinuria is characterized by red
Ravulizumab
Term for several kidney diseases
hence the name, but not all diseases necessarily have an inflammatory component.[citation needed] As it is not strictly a single disease, its presentation
Glomerulonephritis
Partition of vertices of a directed graph
In graph theory, the weak components of a directed graph partition the vertices of the graph into subsets that are totally ordered by reachability. They
Weak_component
Clumping of abnormal cold-sensitive proteins in blood
are abnormal proteins composed of immunoglobulins and sometimes complement components. Cryoglobulins specifically form gel-like solids by clumping together
Cryoglobulinemia
Class of proteins involved in inflammation
growth of microbes, e.g., C-reactive protein, mannose-binding protein, complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin. Others
Acute-phase_protein
Type of hexachord
the augmented triad. Its only five-note subset is 5-21 (0,1,4,5,8), the complement of which is 7-21 (0,1,2,4,5,8,9), the only superset of 6-20. The only
"Ode-to-Napoleon"_hexachord
Protein found in humans
regulate the alternative pathway of the complement system, a key component of innate immunity. It ensures that complement activation is directed against pathogens
Factor_H
Largest structure in the nucleus of eukaryotic cells
Three major components of the nucleolus are recognized: the fibrillar center (FC), the dense fibrillar component (DFC), and the granular component (GC). Transcription
Nucleolus
Link formed from a finite number of twisted sections
cyclicly, and the first component of the first tangle is connected to the second component of the second tangle, the first component of the second tangle
Pretzel_link
Link that consists of finitely many unlinked unknots
in the plane. The two-component unlink, consisting of two non-interlinked unknots, is the simplest possible unlink. An n-component link L ⊂ S3 is an unlink
Unlink
Protein found in humans
cleavage after Arg223 in complement component C2 (-Ser-Leu-Gly-Arg-Lys-Ile-Gln-Ile) and after Arg76 in complement component C4 (-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ile)
Mannan-binding lectin-associated serine protease-2
Mannan-binding_lectin-associated_serine_protease-2
Interlinked multi-loop construction where cutting one loop frees all the others
link complement – of the n-component unlink, since by Brunnianness removing the last link unlinks the others. The link group of the n-component unlink
Brunnian_link
Mammalian protein found in Homo sapiens
cellular activation. It is involved in the complement system due to its capacity to bind inactivated complement component 3b (iC3b). The ITGAM (alpha) subunit
Integrin_alpha_M
Study of mathematical knots
picture of the complement of the Borromean rings. The inhabitant of this link complement is viewing the space from near the red component. The balls in
Knot_theory
Decentralized digital cryptocurrency
reaches $50 billion as of 2025. Alternative currency – Medium of exchange complementing national currenciesPages displaying short descriptions of redirect targets
Bitcoin
Monoclonal antibody
disease (CAD). It is given by intravenous infusion. Sutimlimab prevents complement-enhanced activation of autoimmune human B cells in vitro. The most common
Sutimlimab
Sixth mode of the melodic minor scale
is a seven-note musical scale. It is more commonly known as the Locrian ♮2 scale or the Aeolian ♭5 scale, names that avoid confusion with the diminished
Half_diminished_scale
Genetic disease causing anemia, birth defects, and cancers
of complementation group D1, N, and S, are embryonically lethal in most cases, which might account for the rare observation of these complementation groups
Fanconi_anemia
Heptatonic music scale
♯2 scale is a heptatonic scale subset of the octatonic scale with an omitted ♭2 degree. It has the following interval structure in semitones: 3, 1, 2,
Hungarian_major_scale
Seventh mode of the melodic minor scale
parsimony in the music of Alexander Scriabin", Journal of Music Theory 42, no. 2 ("Neo-Riemannian Theory", Autumn): 219–233. Tymoczko, Dmitri. 1997. "The
Altered_scale
Mammalian protein found in humans
inhibitory complement receptor. CD46 is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At
Membrane_cofactor_protein
Protein-coding gene in the species Homo sapiens
recognition immune clearance, SAP binds in a calcium dependent manner to complement component C1q and the antibody binding region of immunoglobulins (Fab). SAP
Serum_amyloid_P_component
US military transportable X-band surveillance radar
provide the system to Israel, complementing their two-tier Arrow 2 missile and Patriot PAC-3 missile defense. The TPY-2 complements the fixed AN/FPS-129 HAVE
AN/TPY-2_transportable_radar
Topics referred to by the same term
Singapore, station code CR2 Complement receptor 2, an immunological cell surface receptor for a complement component Conserved Region 2, the second conserved
CR2
Mathematical set formed from two given sets
\\X_{1}&X_{2}&\cdots &A_{n-1}^{\complement }&X_{n}\\X_{1}&X_{2}&\cdots &X_{n-1}&A_{n}^{\complement }\end{array}}\right].} The diagonal components of this matrix A i
Cartesian_product
Sixth-generation strike fighter program
and complement the F-35C beginning in the 2030s. A requirement was first identified in June 2008. The F/A-XX is the crewed combat aircraft component and
Boeing_F/A-XX
Set associated with a complex-valued polynomial
component of the complement of the amoeba of p ( z ) {\displaystyle p(z)} . As an example, the Ronkin function of a monomial p ( z ) = a z 1 k 1 z 2 k
Amoeba_(mathematics)
Protein-coding gene in the species Homo sapiens
regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple
V-set and immunoglobulin domain containing 4
V-set_and_immunoglobulin_domain_containing_4
Chemical compound
complement inhibitor that is injected subcutaneously (under the skin). Zilucoplan is a cyclic peptide that binds to the protein complement component 5
Zilucoplan
alignment, component pick-up, component centering/vision inspection, component placement and board indexing. Component pick-up, component centering/vision
Component_placement
Protein domain
calcium. Mammalian complement-activating component of Ra-reactive factor (RARF), a protease that cleaves the C4 component of complement. Vertebrate enteropeptidase
CUB_domain
Type of mathematical knot
knot that contains an incompressible, non boundary-parallel torus in its complement. Every knot is either hyperbolic, a torus, or a satellite knot. The class
Satellite_knot
Royal Navy mobile logistics support for the Fleet Air Arm
details). An MSR unit had its own complement of 3 Officers, 29 CPOs & POs and 99 ratings. Mobile Personnel (MP) - This component was made up of maintenance personnel
Mobile_Naval_Air_Base
Monoclonal antibody
treatment of people with paroxysmal nocturnal hemoglobinuria. It is a complement component 5 (C5) inhibitor. Crovalimab was approved for use in China in February
Crovalimab
Mammalian protein found in humans
Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. DAF regulates the complement
Decay-accelerating_factor
Analog of the knot group
fundamental group of the link complement. The link group of an n-component link is essentially the set of (n + 1)-component links extending this link, up
Link_group
Mammalian protein found in Homo sapiens
identified as a receptor for Chikungunya Virus (CHIKV) and Dengue Virus 2 (DENV-2). Little else is known about the activity of the prohibitins in viral
Prohibitin
Medical condition
can be used to detect certain diseases. C1q is an integral component within the complement pathway – a complicated cascade of protein interactions, culminating
Urticarial_vasculitis
Standard for miniature computer expansion cards
double-sided component population. Consequently, M.2 SSD modules can provide double the storage capacity within the footprint of an mSATA device. M.2 modules
M.2
Pathological embedding of the sphere in 3D space
R n {\displaystyle \mathbb {R} ^{n}} such that the unbounded component of its complement is not simply connected. These are often referred to as higher-dimensional
Alexander_horned_sphere
Life-threatening immune-related blood disease
that frequently has a genetic component. In most cases, it can be effectively controlled by interruption of the complement cascade. Particular monoclonal
Atypical hemolytic uremic syndrome
Atypical_hemolytic_uremic_syndrome
Family of proteins
the complement cascade. Specifically, ficolins bind to acetyl groups present in certain bacterial molecules, such as N-acetylglucosamine, a component of
Ficolin
Subset which is both open and closed
exclusive. A set is closed if its complement is open, which leaves the possibility of an open set whose complement is also open, making both sets both
Clopen_set
Scientific study of how the component parts of fish function together in the living fish
fish anatomy and physiology complement each other, the former dealing with the structure of a fish, its organs or component parts and how they are put
Fish_physiology
Proteins present in blood serum
functioning of the immune system. Other blood proteins act as enzymes, complement, components, protease inhibitors or kinin precursors. Contrary to popular belief
Plasma_protein
Class of enzymes
adipocytes into the bloodstream. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression
Factor_D
American video streaming service
that its control of Hulu was the third major component of its direct-to-consumer strategy, complementing its sports streaming service ESPN+, and its then-forthcoming
Hulu
Largest independent set of paired elements
a dependent set in the cographic matroid. In any connected graph, the complement of a maximum non-separating independent set is a minimum connected vertex
Matroid_parity_problem
Antibody that plays a crucial role in the immune function of mucous membranes
the component of IgA can associate with the mucus layer that sits atop epithelial cells. Since sIgA is a poor opsonin and activator of complement, simply
Immunoglobulin_A
Third mode of the melodic minor scale
augmented scale Modes I, II, III, IV, V, VI, VII Component pitches C, D, E, F♯, G♯, A, B Qualities Number of pitch classes 7 Forte number 7-34 Complement 5-34
Lydian_augmented_scale
Psychological theory
environments that complement their heredity. For example, extroverts may deliberately engage with others like themselves. Niche picking is a component of gene-environment
Niche_picking
Early mechanical calculator
d is 9-d. So the 9's complement of 4 is 5 and the 9's complement of 7 is 2. In a decimal machine with n dials, the 9's complement of a number A is: C 9
Pascaline
Electric pickup truck
up about Hawkins, Andrew J. (November 21, 2019). "Tesla made an ATV to complement its futuristic Cybertruck". The Verge. Archived from the original on November
Tesla_Cybertruck
travel, tourism, insurance
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