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Chemical compound
Trehalose is a sugar derived from two molecules of glucose. Trehalose is a disaccharide formed by a 1,1-glycosidic bond between two α-glucose units. It
Trehalose
Index of enzymes associated with the same name
Trehalose Synthase may refer to: Alpha,alpha-trehalose synthase, an enzyme Maltose alpha-D-glucosyltransferase, an enzyme This set index page lists enzyme
Trehalose_synthase
Class of enzymes
The enzyme trehalose-phosphatase (EC 3.1.3.12) catalyzes the reversible reaction α,α-trehalose 6-phosphate H2O Pi H2O Pi trehalose The enzyme characterised
Trehalose-phosphatase
\rightleftharpoons } alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate Hence, this enzyme has one substrate( alpha,alpha'-trehalose 6-mycolate) and two
Trehalose O-mycolyltransferase
Trehalose_O-mycolyltransferase
Class of enzymes
Trehalose 6-phosphate phosphorylase (EC 2.4.1.216) is an enzyme that catalyzes the chemical reaction trehalose 6-phosphate Pi glucose 6-phosphate
Trehalose 6-phosphate phosphorylase
Trehalose_6-phosphate_phosphorylase
Chemical compound
Cord factor, or trehalose dimycolate (TDM), is a glycolipid molecule found in the cell wall of Mycobacterium tuberculosis and similar species. It is the
Cord_factor
Index of enzymes associated with the same name
Alpha,alpha-trehalose-phosphate synthase may refer to the following: Alpha,alpha-trehalose-phosphate synthase (GDP-forming) Alpha,alpha-trehalose-phosphate
Alpha,alpha-trehalose-phosphate synthase
Alpha,alpha-trehalose-phosphate_synthase
InterPro Family
4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141, malto-oligosyltrehalose trehalohydrolase) is an enzyme with systematic name
4-alpha-D-((1-4)-alpha-D-glucano)trehalose trehalohydrolase
4-alpha-D-((1-4)-alpha-D-glucano)trehalose_trehalohydrolase
Complex sugar
hemiacetal unit that is free to act as a reducing agent. Sucrose and trehalose are examples of non-reducing disaccharides because their glycosidic bond
Disaccharide
Protein-coding gene in the species Homo sapiens
been shown to interact with: Bcl-2 BCL2L2 GOPC MAP1LC3A Rubicon UVRAG Trehalose reduces p62/Beclin-1 ratio and increases autophagy in the frontal cortex
BECN1
Class of enzymes
alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) is an enzyme that catalyzes the chemical reaction trehalose Pi Pi β-D-glucose-1-phosphate +
Alpha,alpha-trehalose phosphorylase
Alpha,alpha-trehalose_phosphorylase
Enzyme family
Alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) is an enzyme that catalyzes the chemical reaction trehalose Pi Pi
Alpha,alpha-trehalose phosphorylase (configuration-retaining)
Alpha,alpha-trehalose_phosphorylase_(configuration-retaining)
Class of enzymes
most forms of life (except mammals), which catalyze the reduction of trehalose (α-D-glucopyranosyl-1,1-α-D-glucopyranoside) - a non-reducing sugar and
Trehalase
Class of enzymes
In enzymology, an alpha,alpha-trehalose-phosphate synthase (GDP-forming) (EC 2.4.1.36) is an enzyme that catalyzes the chemical reaction GDP-glucose +
Alpha,alpha-trehalose-phosphate synthase (GDP-forming)
Alpha,alpha-trehalose-phosphate_synthase_(GDP-forming)
the non-toxic sugar trehalose that is found in the hemolymph of insects to cope with changes in environmental conditions. Trehalose levels can spike up
Enantiostasis
Class of enzymes
Alpha,alpha-trehalose synthase (EC 2.4.1.245, trehalose synthase, trehalose synthetase, UDP-glucose:glucose 1-glucosyltransferase, TreT, PhGT) is an enzyme
Alpha,alpha-trehalose synthase
Alpha,alpha-trehalose_synthase
Class of enzymes
In enzymology, an alpha,alpha-trehalose-phosphate synthase (UDP-forming) (EC 2.4.1.15) is an enzyme that catalyzes the chemical reaction UDP-glucose +
Alpha,alpha-trehalose-phosphate synthase (UDP-forming)
Alpha,alpha-trehalose-phosphate_synthase_(UDP-forming)
Sugars that contain free OH group at the anomeric carbon atom
either reducing or nonreducing. Nonreducing disaccharides like sucrose and trehalose have glycosidic bonds between their anomeric carbons and thus cannot convert
Reducing_sugar
Chemical compound
metabolite. It was synthesized as a sugar-based surfactant containing a trehalose substructure from the condensation of 4-trehalosamine and tetradecanal
IMCTA-C14
Class of enzymes
an enzyme with systematic name α,α-trehalose glucohydrolase. This enzyme catalyzes the chemical reaction trehalose H2O 2 glucose The reaction
Α,α-Trehalase
State of extreme dryness or process of thorough drying
desiccation and that the basis of this ability is founded in the metabolism of trehalose. Several bacterial species have been shown to accumulate DNA damage upon
Desiccation
Polysaccharide gum used as a food additive and thickener
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Xanthan_gum
Long carbohydrate polymers such as starch, glycogen, cellulose, and chitin
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Polysaccharide
Bioactive Natural Product
Lentztrehaloses are a group of trehalose derivatives found in an actinomycete Lentzea sp. ML457-mF8. There are three members of the class, named lentztrehalose
Lentztrehalose
Organic compound that consists only of carbon, hydrogen, and oxygen
xylose, ribose Disaccharides Sucrose, lactose, maltose, isomaltulose, trehalose Polyols Sorbitol, mannitol Oligosaccharides (3–9) Malto-oligosaccharides
Carbohydrate
Species of fungus
goods such as cookies. The sweet taste may be due to the presence of trehalose, a type of sugar that allows the mushroom to resist death by desiccation
Marasmius_oreades
Chemical compound
Trehalosamines are amino sugars in which a hydroxyl group of trehalose is replaced with an amino group. While 2-, 3-, and 4-trehalosamine derived from
Trehalosamine
Glucose polymer used as energy store in plants
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Starch
Index of chemical compounds with the same molecular formula
3α-Mannobiose Melibiose Melibiulose Nigerose Sophorose Sucrose (table sugar) Trehalose Trehalulose Turanose This set index page lists chemical structure articles
C12H22O11
Hormones regulating blood sugar levels
disaccharide trehalose. Trehalose is the major carbohydrate used by insects for flight. The concentrations of the carbohydrates trehalose and glucose in
Blood_sugar_regulation
Substance used to protect biological tissue from freezing damage
cryoprotectants to store genetic material with the intention of future revival. Trehalose is non-reducing sugar produced by yeasts and insects in copious amounts
Cryoprotectant
Polysaccharide of glucose
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Maltodextrin
Natural plant polysaccharides
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Inulin
Covalent bond joining a sugar molecule to another group
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Glycosidic_bond
Sorbose Sedoheptulose Talose Tagatose Xylose Xylulose Disaccharides Lactose Trehalose Turanose Maltose Neohesperidose Robinose Rutinose Sucrose (also called
List_of_sugars
Species of bacterium
evidence of urease activity and the ability to use sucrose, mannose, and trehalose. S. felis has been isolated from and is associated with skin infections
Staphylococcus_felis
Simple sugars such as glucose and fructose
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Monosaccharide
Long-chain polymer of a N-acetylglucosamine
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Chitin
Basic taste
Sweetness Lactose Disaccharide 0.16 Maltose Disaccharide 0.33 – 0.45 Trehalose (α,α-trehalose) Disaccharide max. 0.45 Isomaltulose Disaccharide 0.40 - 0.50 L-serine
Sweetness
Transformation of a substance into a glass
vitrification solutions Formula Tg (Mid, °C) 1M sucrose -30.9 1M glucose -41.3 1M trehalose -68.0 50% sucrose + 50% glycerol (PVS3) -90.7 50% sucrose + 50% (ethylene
Vitrification
Class of enzymes
α-trehalose 6-phosphate H2O glucose 6-phosphate + D-glucose The enzyme characterised from Bacillus popilliae hydrolyses α,α-trehalose 6-phosphate
Α,α-phosphotrehalase
Metabolic state of life
contract into a smaller shape and some proceed to form a sugar called trehalose, a disaccharide consisting of two molecules of glucose with high water
Cryptobiosis
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Galactan
Chemical property of substances
proceed. Enzyme function at higher temperatures may be enhanced with trehalose, which opens up the possibility of using normally thermolabile enzymes
Thermolabile
Phylum of microscopic animals
levels of the sugar trehalose, common in organisms that survive desiccation. However, tardigrades do not synthesize enough trehalose for this function.
Tardigrade
Species of spore-bearing plant
water, avoiding tissue and cell damage during drying by synthesizing trehalose, a crystallized sugar that acts as a compatible solute. Dissolved salts
Selaginella_lepidophylla
Bloodlike fluid in arthropods
urea. Arthropod hormones are present, most notably the juvenile hormone. Trehalose can be present and sometimes in great amounts along with glucose. These
Hemolymph
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Allulose
American physiologist
tardigrades. His work included the discovery of trehalose as a cryoprotectant for cell membranes and the use of trehalose and other cryoprotectants for the preservation
John_H._Crowe
Chemical compound
data sheet (SDS) External MSDS Related compounds Related Sucrose Lactose Trehalose Cellobiose Except where otherwise noted, data are given for materials
Maltose
Sweet-tasting, water-soluble carbohydrates
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Sugar
Species of bacterium
Galactose + D-Glucose + D-Fructose V D-Mannose V Mannitol V N-Acetylglucosamine + Amygdalin – Maltose + D-Melibiose – D-Trehalose – Glycogen + D-Turanose +
Vibrio_natriegens
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Chitin-glucan_complex
Genus of flowering plants
The ability of the plant to do this is attributed to the presence of trehalose, a disaccharide sugar involved in several mechanisms of cryptobiosis.
Anastatica
Disaccharide made of glucose and fructose
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Sucrose
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Galactose-α-1,3-galactose
Mixture of short-chain carbohydrates
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Isomaltooligosaccharide
Glucose polymer used as energy store in animals
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Glycogen
Species of fly
Slow desiccation (0.22 ml per day) enabled larvae to synthesize 38 μg trehalose/individual, and all of them recovered after rehydration, whereas larvae
Polypedilum_vanderplanki
Legume grown for its edible bean
humans and other monogastric animals, comparable to the disaccharide trehalose. Undigested oligosaccharides are broken down in the intestine by native
Soybean
Oligosaccharide fructans
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Fructooligosaccharide
Species of fly
hardening. To adapt to the cold temperatures, B. antarctica accumulates trehalose, glucose, and erythritol. These compounds help the insect survive freezing
Belgica_antarctica
Species of plant
of organism and thus conserve energy. Trehalose synthesis genes were also found to be overexpressed; trehalose is a sugar that in high concentrations
Phaseolus_acutifolius
Fructose polymer
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Fructan
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Sinistrin
Chemical compound
Noiles, E., Thompson, K. (1998). "Comparison of Glycerol, Other Polyols, Trehalose, and Raffinose to Provide a Defined Cryoprotectant Medium for Mouse Sperm
Raffinose
Class of chemical compounds
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Beta-glucan
Species of bacterium
α-Galactosidase – + β-Galactosidase – + β-Glucuronidase + – Acid produced from trehalose + – Acid produced from lactose +/- + Methyl-D-glucopyranoside +/- +
Streptococcus_canis
Naming system for building blocks of carbohydrate
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Monosaccharide_nomenclature
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Dextran
Species of fungus
mycelium is formed. It differs from other species by the assimilation of trehalose, melezitose, and xylitol, and is reproductively isolated. Its type strain
Kodamaea_kakaduensis
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Amylose
Genus of bacteria
D-melibiose, D-cellobiose, D-mannitol, D-mannose, L-rhamnose, L-arabinose, D-trehalose, galacturonate and D-maltose. Cronobacter spp. are also generally positive
Cronobacter
Phylum of pseudocoelomate invertebrates
linked to the production of trehalose, a non-reducing disaccharide (sugar), bdelloids apparently cannot synthesise trehalose. In bdelloids, a major cause
Rotifer
Species of bacterium
hominis, which is also sensitive. In this case, the production of acid from trehalose by S. hominis can be used to tell the two species apart.[citation needed]
Staphylococcus_epidermidis
Carbohydrate
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Lactose
Monosaccharide sugar
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Galactose
receptor that can recognize glycolipids including mycobacterial cord factor, trehalose-6,6'-dimycolate (TDM). The mincle receptor binds a range of carbohydrate
Mincle_receptor
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Amylopectin
Naturally produced monosaccharide
5-lactone. Glucose is used in some bacteria as a building block in the trehalose or the dextran biosynthesis and in animals as a building block of glycogen
Glucose
Human body core temperature below 35 °C (95 °F)
temperatures by replacing most of their internal water with the sugar trehalose solution, preventing the crystallization that otherwise damages cell membranes
Hypothermia
Group of low-molecular-weight carbohydrates
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Dextrin
Genetic neurodegenerative disease
and their issues with swallowing. Some experimental treatments using trehalose have been suggested. In 2021, the FDA accepted an Investigational New
Machado–Joseph_disease
Predatory order of arachnids
ability to withstand the cold may be related to the increase in the sugar trehalose when the temperature drops. Some species hibernate. Scorpions have immunity
Scorpion
Species of fungus
is a gray area. N. glabratus ferments and assimilates only glucose and trehalose, opposing to Candida species and this repertoire of sugar utilization
Nakaseomyces_glabratus
Colonial flying insect
fructose and glucose but the most common circulating sugar in hemolymph is trehalose which is a disaccharide consisting of two glucose molecules. Adult worker
Honey_bee
Genus of bacteria
acids in their cell wall. Majority of strains possess the cord factor (trehalose 6-6' dimycolate), an important virulence factor. They are catalase positive
Nocardia
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Fucose
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Tagatose
Chemical compound
; Hong, S. K.; Seo, Y. G.; Kim, C. J. (2011). "Enhanced production of trehalose in Escherichia coli by homologous expression of otsBA in the presence
Validamycin
Class of saccharide compounds structured as a 5-carbon, 1-oxygen ring
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Pyranose
Progressive neurological disease
announced completion of Phase 2a clinical trials of their medication, trehalose, in the treatment of SCA3. BioBlast has received FDA Fast Track status
Spinocerebellar_ataxia
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Levan_polysaccharide
\rightleftharpoons } alpha,alpha-trehalose Hence, this enzyme has one substrate, maltose, and one product, alpha,alpha-trehalose. This enzyme belongs to the
Maltose alpha-D-glucosyltransferase
Maltose_alpha-D-glucosyltransferase
Chemical compound
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Idose
Species of bacterium
Streptococcus anginosus strains produce acetoin from glucose, ferment lactose, trehalose, salicin, and sucrose, and hydrolyze esculin and arginine. Carbon dioxide
Streptococcus_anginosus
Species of fungus
Glucose and trehalose are fermented by H. nectarophila; trehalose fermentation is uncommon among its closest relatives, making trehalose fermentation
Hanseniaspora_nectarophila
Species of fungus
accumulate a sugar named trehalose (this sugar is usually found in insects) as thermo-protective compound. It was shown that trehalose synthesis is not required
Ogataea_polymorpha
Catalase-positive bacterium
Galactose + D-Glucose + D-Fructose + D-Mannose + Mannitol + N-Acetylglucosamine + Amygdalin + Maltose + D-Melibiose + D-Trehalose + Glycogen + D-Turanose +
Bacillus_subtilis
Structures of cyclohexane
Cellobiose Isomaltose Isomaltulose Lactose Lactulose Maltose Sucrose Trehalose Turanose Trisaccharides Maltotriose Melezitose Raffinose Tetrasaccharides
Cyclohexane_conformation
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TREHALOSE
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